LT3390358T - Kristalinis eravaciklino bis-hidrochloridas - Google Patents
Kristalinis eravaciklino bis-hidrochloridasInfo
- Publication number
- LT3390358T LT3390358T LTEP17701668.0T LT17701668T LT3390358T LT 3390358 T LT3390358 T LT 3390358T LT 17701668 T LT17701668 T LT 17701668T LT 3390358 T LT3390358 T LT 3390358T
- Authority
- LT
- Lithuania
- Prior art keywords
- hydrochloride
- eravacycline bis
- crystalline eravacycline
- crystalline
- bis
- Prior art date
Links
- HLFSMUUOKPBTSM-ISIOAQNYSA-N chembl1951095 Chemical compound C([C@H]1C[C@H]2[C@@H](C(=C(C(N)=O)C(=O)[C@@]2(O)C(O)=C1C(=O)C1=C2O)O)N(C)C)C1=C(F)C=C2NC(=O)CN1CCCC1 HLFSMUUOKPBTSM-ISIOAQNYSA-N 0.000 title 1
- 229950004877 eravacycline Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16152468 | 2016-01-22 | ||
| PCT/EP2017/051203 WO2017125557A1 (en) | 2016-01-22 | 2017-01-20 | Crystalline eravacycline bis-hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3390358T true LT3390358T (lt) | 2020-11-25 |
Family
ID=55272232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP17701668.0T LT3390358T (lt) | 2016-01-22 | 2017-01-20 | Kristalinis eravaciklino bis-hidrochloridas |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10975029B2 (lt) |
| EP (2) | EP3778567A1 (lt) |
| JP (2) | JP7046815B2 (lt) |
| CN (1) | CN108495844B (lt) |
| AU (1) | AU2017208574B2 (lt) |
| CA (1) | CA3011323A1 (lt) |
| ES (1) | ES2834049T3 (lt) |
| LT (1) | LT3390358T (lt) |
| PT (1) | PT3390358T (lt) |
| WO (1) | WO2017125557A1 (lt) |
| ZA (1) | ZA201804685B (lt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2883238C (en) | 2012-08-31 | 2021-11-23 | Tetraphase Pharmaceuticals, Inc. | Tetracycline compounds |
| EP3778567A1 (en) * | 2016-01-22 | 2021-02-17 | Sandoz Ag | Crystalline eravacycline bis-hydrochloride |
| HUE066360T2 (hu) | 2016-10-19 | 2024-07-28 | Tetraphase Pharmaceuticals Inc | Eravaciklin kristályformái |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE758350A (fr) * | 1969-12-30 | 1971-05-03 | Pfizer | Procede de fabrication des sels mono- et bi-metalliques alcalins de l'alpha-carboxybenzylpenicilline |
| US4432987A (en) * | 1982-04-23 | 1984-02-21 | Pfizer Inc. | Crystalline benzenesulfonate salts of sultamicillin |
| US5721359A (en) * | 1993-03-12 | 1998-02-24 | Pharmacia & Upjohn Company | Crystalline ceftiofur free acid |
| US7145002B2 (en) * | 2001-09-26 | 2006-12-05 | Merck & Co. Inc. | Crystalline forms of carbapenem antibiotics and methods of preparation |
| KR101746795B1 (ko) | 2008-08-08 | 2017-06-13 | 테트라페이즈 파마슈티컬스, 인코포레이티드 | C7-플루오로 치환된 테트라시클린 화합물 |
| WO2010129057A2 (en) * | 2009-05-08 | 2010-11-11 | Tetraphase Pharmaceuticals, Inc. | Tetracycline compounds |
| WO2012021829A1 (en) | 2010-08-12 | 2012-02-16 | Tetraphase Pharmaceuticals, Inc. | Methods of treating bacterial infections |
| EP3778567A1 (en) * | 2016-01-22 | 2021-02-17 | Sandoz Ag | Crystalline eravacycline bis-hydrochloride |
| HUE066360T2 (hu) | 2016-10-19 | 2024-07-28 | Tetraphase Pharmaceuticals Inc | Eravaciklin kristályformái |
-
2017
- 2017-01-20 EP EP20195549.9A patent/EP3778567A1/en not_active Withdrawn
- 2017-01-20 ES ES17701668T patent/ES2834049T3/es active Active
- 2017-01-20 CA CA3011323A patent/CA3011323A1/en active Pending
- 2017-01-20 CN CN201780007660.4A patent/CN108495844B/zh active Active
- 2017-01-20 WO PCT/EP2017/051203 patent/WO2017125557A1/en not_active Ceased
- 2017-01-20 US US16/071,170 patent/US10975029B2/en active Active
- 2017-01-20 PT PT177016680T patent/PT3390358T/pt unknown
- 2017-01-20 JP JP2018538082A patent/JP7046815B2/ja active Active
- 2017-01-20 EP EP17701668.0A patent/EP3390358B1/en active Active
- 2017-01-20 LT LTEP17701668.0T patent/LT3390358T/lt unknown
- 2017-01-20 AU AU2017208574A patent/AU2017208574B2/en active Active
-
2018
- 2018-07-13 ZA ZA2018/04685A patent/ZA201804685B/en unknown
-
2021
- 2021-04-09 US US17/226,367 patent/US20210253521A1/en not_active Abandoned
- 2021-12-03 JP JP2021196691A patent/JP2022046485A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN108495844B (zh) | 2022-12-02 |
| JP2019502730A (ja) | 2019-01-31 |
| AU2017208574B2 (en) | 2022-09-22 |
| US20200199070A1 (en) | 2020-06-25 |
| ZA201804685B (en) | 2019-04-24 |
| CA3011323A1 (en) | 2017-07-27 |
| EP3778567A1 (en) | 2021-02-17 |
| JP2022046485A (ja) | 2022-03-23 |
| PT3390358T (pt) | 2020-11-09 |
| WO2017125557A1 (en) | 2017-07-27 |
| US10975029B2 (en) | 2021-04-13 |
| JP7046815B2 (ja) | 2022-04-04 |
| US20210253521A1 (en) | 2021-08-19 |
| ES2834049T3 (es) | 2021-06-16 |
| EP3390358A1 (en) | 2018-10-24 |
| EP3390358B1 (en) | 2020-09-23 |
| CN108495844A (zh) | 2018-09-04 |
| AU2017208574A1 (en) | 2018-08-02 |
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