LT3397622T - Hidroksipropiltiazolidino karboksamido darinio alfa-amino esterio ir tokolitinio agento įvedimas kartu - Google Patents

Hidroksipropiltiazolidino karboksamido darinio alfa-amino esterio ir tokolitinio agento įvedimas kartu

Info

Publication number: LT3397622T
Authority: LT; Lithuania
Prior art keywords: alpha; administration; amino ester; carboxamide derivative; tocolytic agent
Prior art date: 2016-01-04

Application number

LTEPPCT/EP2017/050099T

Other languages

English (en)

Inventor

Patrick NAXOS PAGE

Matthias Schwarz

Catherine Jorand-Lebrun

Anna Quattropani

Vincent Pomel

Ernest Loumaye

Oliver Pohl

Jean-Pierre Gotteland

Original Assignee

ObsEva S.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-01-04

Filing date

2017-01-04

Publication date

2022-06-27

2016-01-04 Priority claimed from US14/987,586 external-priority patent/US9447055B1/en

2017-01-04 Application filed by ObsEva S.A. filed Critical ObsEva S.A.

2022-06-27 Publication of LT3397622T publication Critical patent/LT3397622T/lt

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pregnancy & Childbirth (AREA)
Gynecology & Obstetrics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Thiazole And Isothizaole Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Cephalosporin Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Rheumatology (AREA)
Pyrrole Compounds (AREA)
Pain & Pain Management (AREA)
Medicinal Preparation (AREA)
Emergency Medicine (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Investigating Or Analysing Biological Materials (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

LTEPPCT/EP2017/050099T 2016-01-04 2017-01-04 Hidroksipropiltiazolidino karboksamido darinio alfa-amino esterio ir tokolitinio agento įvedimas kartu LT3397622T (lt)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US201662274674P	2016-01-04	2016-01-04
US14/987,586 US9447055B1 (en)	2016-01-04	2016-01-04	α-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof
US201662395664P	2016-09-16	2016-09-16
US201662407918P	2016-10-13	2016-10-13
PCT/EP2017/050099 WO2017118639A1 (en)	2016-01-04	2017-01-04	Alpha-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof

Publications (1)

Publication Number	Publication Date
LT3397622T true LT3397622T (lt)	2022-06-27

Family

ID=57799697

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
LTEPPCT/EP2017/050099T LT3397622T (lt)	2016-01-04	2017-01-04	Hidroksipropiltiazolidino karboksamido darinio alfa-amino esterio ir tokolitinio agento įvedimas kartu
LTEPPCT/EP2017/050101T LT3400217T (lt)	2016-01-04	2017-01-04	Hidroksipropiltiazolidino karboksamido l-valinato darinys, jo druska ir jo kristalinė forma

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
LTEPPCT/EP2017/050101T LT3400217T (lt)	2016-01-04	2017-01-04	Hidroksipropiltiazolidino karboksamido l-valinato darinys, jo druska ir jo kristalinė forma

Country Status (25)

Country	Link
EP (4)	EP3397622B1 (lt)
JP (6)	JP6933322B2 (lt)
KR (3)	KR20180100120A (lt)
CN (1)	CN108779087A (lt)
AU (5)	AU2017205254B2 (lt)
CA (2)	CA3009576A1 (lt)
CY (2)	CY1125223T1 (lt)
DK (2)	DK3397622T3 (lt)
EA (1)	EA036990B1 (lt)
ES (2)	ES2915948T3 (lt)
HR (2)	HRP20220673T1 (lt)
HU (2)	HUE058872T2 (lt)
IL (5)	IL318222A (lt)
LT (2)	LT3397622T (lt)
MA (2)	MA43580A (lt)
MX (3)	MX379544B (lt)
PL (2)	PL3397622T3 (lt)
PT (2)	PT3397622T (lt)
RS (2)	RS63285B1 (lt)
SG (4)	SG10202009723PA (lt)
SI (2)	SI3397622T1 (lt)
SM (2)	SMT202200248T1 (lt)
UA (2)	UA125118C2 (lt)
WO (2)	WO2017118641A1 (lt)
ZA (1)	ZA201903769B (lt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2915948T3 (es) *	2016-01-04	2022-06-27	ObsEva SA	Administración conjunta de alfa-aminoéster de derivado de hidroxipropiltiazolidin-carboxamida y un agente tocolítico
RU2711615C1 (ru) *	2019-09-12	2020-01-17	Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт акушерства, гинекологии и репродуктологии имени Д.О. Отта"	Способ лечения эндометриоза на основании экспериментальной модели у крыс
US20220339176A1 (en) *	2019-09-23	2022-10-27	The Board Of Trustees Of The Leland Stanford Junior University	Methods of Treatments to Prolong Gestation and Complications of Menstruation or Gestation
US12426782B2 (en)	2020-11-06	2025-09-30	The Board Of Trustees Of The Leland Stanford Junior University	Systems and temporal alignment methods for evaluation of gestational age and time to delivery
US20240024295A1 (en) *	2020-12-11	2024-01-25	Elise A. Olsen	Compositions and methods for inhibiting hair growth

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US4108846A (en)	1977-02-01	1978-08-22	Hoffmann-La Roche Inc.	Solid phase synthesis with base N alpha-protecting group cleavage
SE430885B (sv)	1980-03-24	1983-12-19	Ferring Ab	Oxytocin-derivat
US4508657A (en)	1982-01-19	1985-04-02	Research Corporation	Peptide synthesis and amino acid blocking agents
US4581167A (en)	1982-01-19	1986-04-08	Research Corporation	Peptide synthesis and amino acid blocking agents
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ES2360882T3 (es)	2002-03-28	2011-06-10	Merck Serono Sa	Derivados de tiazolidina carboxamida como moduladores del receptor de prostaglandina f.
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US7521530B2 (en) *	2002-06-11	2009-04-21	Universite De Montreal	Peptides and peptidomimetics useful for inhibiting the activity of prostaglandin F2α receptor
UA78058C2 (en)	2002-07-05	2007-02-15	Applied Research Systems	Pyrrolidine derivative as oxitocin antagonists
PL377287A1 (pl) *	2002-12-12	2006-01-23	Idenix (Cayman) Limited	Sposób wytwarzania 2'-rozgałęzionych nukleozydów
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EP2886107A1 (en)	2013-12-17	2015-06-24	ObsEva S.A.	Oral formulations of pyrrolydine derivatives
AU2014397706A1 (en) *	2014-06-16	2016-12-22	Glaxosmithkline Intellectual Property Development Limited	Retosiban for the treatment of pre-term labour
EP3753921A1 (en)	2014-07-02	2020-12-23	ObsEva S.A.	Crystalline (3z,5s)-5-(hydroxymethyl)-1-[(2'-methyl-1,1'-biphenyl-4-yl)carbonyl]pyrrolidin-3-one o-methyloxime useful in methods of treating conditions related to the ot-r activity
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ES2915948T3 (es) *	2016-01-04	2022-06-27	ObsEva SA	Administración conjunta de alfa-aminoéster de derivado de hidroxipropiltiazolidin-carboxamida y un agente tocolítico
US9447055B1 (en) *	2016-01-04	2016-09-20	Merck Serono S.A.	α-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof

2017
- 2017-01-04 ES ES17700391T patent/ES2915948T3/es active Active
- 2017-01-04 LT LTEPPCT/EP2017/050099T patent/LT3397622T/lt unknown
- 2017-01-04 AU AU2017205254A patent/AU2017205254B2/en active Active
- 2017-01-04 EP EP17700391.0A patent/EP3397622B1/en active Active
- 2017-01-04 EP EP22153566.9A patent/EP4144351A1/en active Pending
- 2017-01-04 IL IL318222A patent/IL318222A/en unknown
- 2017-01-04 SI SI201731162T patent/SI3397622T1/sl unknown
- 2017-01-04 PL PL17700391T patent/PL3397622T3/pl unknown
- 2017-01-04 RS RS20220547A patent/RS63285B1/sr unknown
- 2017-01-04 AU AU2017205670A patent/AU2017205670B2/en active Active
- 2017-01-04 CA CA3009576A patent/CA3009576A1/en active Pending
- 2017-01-04 JP JP2018529634A patent/JP6933322B2/ja active Active
- 2017-01-04 ES ES17700392T patent/ES2916835T3/es active Active
- 2017-01-04 LT LTEPPCT/EP2017/050101T patent/LT3400217T/lt unknown
- 2017-01-04 HR HRP20220673TT patent/HRP20220673T1/hr unknown
- 2017-01-04 WO PCT/EP2017/050101 patent/WO2017118641A1/en not_active Ceased
- 2017-01-04 KR KR1020187018312A patent/KR20180100120A/ko not_active Ceased
- 2017-01-04 PL PL17700392T patent/PL3400217T3/pl unknown
- 2017-01-04 SG SG10202009723PA patent/SG10202009723PA/en unknown
- 2017-01-04 MA MA043580A patent/MA43580A/fr unknown
- 2017-01-04 EP EP22152238.6A patent/EP4140988A1/en active Pending
- 2017-01-04 UA UAA201806830A patent/UA125118C2/uk unknown
- 2017-01-04 DK DK17700391.0T patent/DK3397622T3/da active
- 2017-01-04 WO PCT/EP2017/050099 patent/WO2017118639A1/en not_active Ceased
- 2017-01-04 IL IL284912A patent/IL284912B/en unknown
- 2017-01-04 CN CN201780015011.9A patent/CN108779087A/zh active Pending
- 2017-01-04 KR KR1020257022032A patent/KR20250107965A/ko active Pending
- 2017-01-04 MX MX2018008304A patent/MX379544B/es unknown
- 2017-01-04 JP JP2018529284A patent/JP7169573B2/ja active Active
- 2017-01-04 HU HUE17700391A patent/HUE058872T2/hu unknown
- 2017-01-04 UA UAA201806074A patent/UA125377C2/uk unknown
- 2017-01-04 SI SI201731161T patent/SI3400217T1/sl unknown
- 2017-01-04 PT PT177003910T patent/PT3397622T/pt unknown
- 2017-01-04 SG SG11201804594YA patent/SG11201804594YA/en unknown
- 2017-01-04 SG SG10202009769WA patent/SG10202009769WA/en unknown
- 2017-01-04 DK DK17700392.8T patent/DK3400217T3/da active
- 2017-01-04 SM SM20220248T patent/SMT202200248T1/it unknown
- 2017-01-04 HR HRP20220674TT patent/HRP20220674T1/hr unknown
- 2017-01-04 CA CA3009573A patent/CA3009573A1/en active Pending
- 2017-01-04 HU HUE17700392A patent/HUE058871T2/hu unknown
- 2017-01-04 SM SM20220249T patent/SMT202200249T1/it unknown
- 2017-01-04 SG SG11201804789QA patent/SG11201804789QA/en unknown
- 2017-01-04 PT PT177003928T patent/PT3400217T/pt unknown
- 2017-01-04 EA EA201891095A patent/EA036990B1/ru unknown
- 2017-01-04 KR KR1020187018929A patent/KR102795275B1/ko active Active
- 2017-01-04 RS RS20220548A patent/RS63286B1/sr unknown
- 2017-01-04 MA MA043549A patent/MA43549A/fr unknown
- 2017-01-04 MX MX2018008157A patent/MX389261B/es unknown
- 2017-01-04 EP EP17700392.8A patent/EP3400217B1/en active Active
2018
- 2018-05-31 IL IL259742A patent/IL259742B/en unknown
- 2018-06-26 IL IL260286A patent/IL260286B/en unknown
- 2018-06-29 MX MX2022000154A patent/MX2022000154A/es unknown
2019
- 2019-05-24 ZA ZA2019/03769A patent/ZA201903769B/en unknown
2021
- 2021-08-05 JP JP2021129297A patent/JP7432284B2/ja active Active
- 2021-08-16 AU AU2021218009A patent/AU2021218009B2/en active Active
- 2021-12-22 IL IL289256A patent/IL289256A/en unknown
2022
- 2022-06-01 CY CY20221100383T patent/CY1125223T1/el unknown
- 2022-06-01 CY CY20221100384T patent/CY1125231T1/el unknown
- 2022-10-18 JP JP2022166814A patent/JP7377588B2/ja active Active
2023
- 2023-09-21 AU AU2023233151A patent/AU2023233151A1/en not_active Abandoned
- 2023-10-25 JP JP2023183345A patent/JP2024012376A/ja active Pending
2025
- 2025-09-04 JP JP2025147215A patent/JP2026000959A/ja active Pending
- 2025-10-22 AU AU2025256134A patent/AU2025256134A1/en active Pending

Also Published As

Publication number	Publication date
UA125377C2 (uk)	2022-03-02
DK3400217T3 (da)	2022-06-07
JP2024012376A (ja)	2024-01-30
SI3397622T1 (sl)	2022-07-29
IL284912A (en)	2021-08-31
WO2017118639A1 (en)	2017-07-13
SG11201804789QA (en)	2018-07-30
IL284912B (en)	2022-07-01
ES2915948T3 (es)	2022-06-27
EP3400217B1 (en)	2022-03-09
SMT202200249T1 (it)	2022-07-21
KR20180099708A (ko)	2018-09-05
MX2018008304A (es)	2019-01-24
AU2017205254A1 (en)	2018-08-16
IL259742B (en)	2021-08-31
MX379544B (es)	2025-03-11
KR102795275B1 (ko)	2025-04-11
IL289256A (en)	2022-02-01
WO2017118641A1 (en)	2017-07-13
AU2021218003A1 (en)	2021-09-02
PL3400217T3 (pl)	2022-07-04
PT3400217T (pt)	2022-06-15
IL259742A (en)	2018-07-31
IL260286A (en)	2018-07-31
SG10202009769WA (en)	2020-11-27
MA43580A (fr)	2021-05-26
CY1125231T1 (el)	2025-03-28
AU2025256134A1 (en)	2025-11-13
MX2022000154A (es)	2022-02-21
IL318222A (en)	2025-03-01
AU2017205670A1 (en)	2018-08-16
RS63286B1 (sr)	2022-06-30
AU2021218009A1 (en)	2021-09-09
SMT202200248T1 (it)	2022-07-21
CA3009573A1 (en)	2017-07-13
EP3397622A1 (en)	2018-11-07
DK3397622T3 (en)	2022-06-07
UA125118C2 (uk)	2022-01-12
JP7169573B2 (ja)	2022-11-11
SG10202009723PA (en)	2020-11-27
EA201891095A1 (ru)	2019-01-31
CA3009576A1 (en)	2017-07-13
HUE058871T2 (hu)	2022-09-28
AU2017205254B2 (en)	2021-05-20
LT3400217T (lt)	2022-06-27
JP2023002668A (ja)	2023-01-10
PT3397622T (pt)	2022-06-15
CN108779087A (zh)	2018-11-09
CY1125223T1 (el)	2025-03-28
ES2916835T3 (es)	2022-07-06
EP4140988A1 (en)	2023-03-01
SG11201804594YA (en)	2018-06-28
AU2017205670B2 (en)	2021-05-20
PL3397622T3 (pl)	2022-07-04
AU2023233151A1 (en)	2023-10-12
HRP20220674T1 (hr)	2022-07-22
EP4144351A1 (en)	2023-03-08
JP2019500351A (ja)	2019-01-10
EA036990B1 (ru)	2021-01-25
JP2019501897A (ja)	2019-01-24
SI3400217T1 (sl)	2022-07-29
EP3397622B1 (en)	2022-03-09
KR20180100120A (ko)	2018-09-07
JP7377588B2 (ja)	2023-11-10
JP2026000959A (ja)	2026-01-06
IL260286B (en)	2022-02-01
HUE058872T2 (hu)	2022-09-28
AU2021218009B2 (en)	2023-06-22
JP6933322B2 (ja)	2021-09-08
KR20250107965A (ko)	2025-07-14
JP7432284B2 (ja)	2024-02-16
MA43549A (fr)	2021-05-26
MX2018008157A (es)	2018-09-03
ZA201903769B (en)	2023-03-29
MX389261B (es)	2025-03-20
HRP20220673T1 (hr)	2022-07-08
RS63285B1 (sr)	2022-06-30
JP2021178858A (ja)	2021-11-18
EP3400217A1 (en)	2018-11-14

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