LT3444268T - Staphylococcus aureus leukocidinai, terapinės kompozicijos ir jų panaudojimo būdai - Google Patents

Staphylococcus aureus leukocidinai, terapinės kompozicijos ir jų panaudojimo būdai

Info

Publication number
LT3444268T
LT3444268T LTEP18196549.2T LT18196549T LT3444268T LT 3444268 T LT3444268 T LT 3444268T LT 18196549 T LT18196549 T LT 18196549T LT 3444268 T LT3444268 T LT 3444268T
Authority
LT
Lithuania
Prior art keywords
leukocidines
staphylococcus aureus
therapeutic compositions
therapeutic
compositions
Prior art date
Application number
LTEP18196549.2T
Other languages
English (en)
Inventor
Victor J Torres
Ashley L DUMONT
Original Assignee
New York University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York University filed Critical New York University
Publication of LT3444268T publication Critical patent/LT3444268T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Gram-positive bacteria
    • C07K16/1271Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5035Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on sub-cellular localization
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56938Staphylococcus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/305Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F)
    • G01N2333/31Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F) from Staphylococcus (G)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
LTEP18196549.2T 2010-05-05 2011-05-05 Staphylococcus aureus leukocidinai, terapinės kompozicijos ir jų panaudojimo būdai LT3444268T (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33155010P 2010-05-05 2010-05-05

Publications (1)

Publication Number Publication Date
LT3444268T true LT3444268T (lt) 2022-04-11

Family

ID=44902083

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP18196549.2T LT3444268T (lt) 2010-05-05 2011-05-05 Staphylococcus aureus leukocidinai, terapinės kompozicijos ir jų panaudojimo būdai

Country Status (21)

Country Link
US (5) US9783582B2 (lt)
EP (4) EP3444268B1 (lt)
JP (4) JP6031029B2 (lt)
KR (3) KR20190133290A (lt)
CN (2) CN103025352B (lt)
AU (5) AU2011247989C1 (lt)
BR (1) BR112012029521A2 (lt)
CA (2) CA3088918A1 (lt)
DK (1) DK3444268T3 (lt)
ES (2) ES2904314T3 (lt)
HR (1) HRP20220068T1 (lt)
HU (1) HUE058787T2 (lt)
IL (2) IL274109B2 (lt)
LT (1) LT3444268T (lt)
MX (4) MX2012012859A (lt)
MY (1) MY165618A (lt)
PL (1) PL3444268T3 (lt)
RU (2) RU2677140C1 (lt)
SI (1) SI3444268T1 (lt)
WO (1) WO2011140337A2 (lt)
ZA (4) ZA201208455B (lt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2677140C1 (ru) 2010-05-05 2019-01-15 Нью-Йорк Юниверсити Лейкоцидины staphylococcus aureus, терапевтические композиции и их применение
MX357938B (es) * 2011-06-19 2018-07-31 Univ New York Metodos para tratar y prevenir infecciones por staphylococcus aureus y afecciones asociadas.
AU2013251165B2 (en) 2012-04-17 2017-08-24 Arsanis Biosciences Gmbh Cross-reactive Staphylococcus aureus antibody
US9657103B2 (en) 2012-05-02 2017-05-23 New York University Methods of treating and preventing Staphylococcus aureus infections and associated conditions
KR101826538B1 (ko) * 2012-05-30 2018-02-07 현대자동차 주식회사 차량용 글래스 몰딩 부착 장치 및 그 방법
US20160108106A1 (en) * 2013-05-21 2016-04-21 Arsanis Biosciences Gmbh Generation of highly potent antibodies neutralizing the lukgh (lukab) toxin of staphylococcus aureus
WO2014205127A2 (en) 2013-06-18 2014-12-24 New York University Cellular factors involved in the cytotoxicity of staphylococcus aureus leukocidins: novel therapeutic targets
EP3057989A1 (en) * 2013-10-17 2016-08-24 ARSANIS Biosciences GmbH Cross-reactive staphylococcus aureus antibody sequences
MX2016007533A (es) 2013-12-09 2016-12-14 Univ New York Composiciones y metodos para el suministro fagocitico de agentes anti-estafilococicos.
MX2016007212A (es) * 2013-12-19 2016-09-07 Arsanis Biosciences Gmbh Anticuerpos dirigidos contra la toxina lukgh (lukab) de staphylococcus aureus y secuencias de anticuerpos.
WO2016197071A1 (en) * 2015-06-05 2016-12-08 New York University Compositions and methods for anti-staphylococcal biologic agents
WO2018165089A1 (en) * 2017-03-06 2018-09-13 Vanderbilt University Human monoclonal antibodies to staphylococcus aureus lukab toxin
EP3638286A4 (en) * 2017-06-13 2021-03-10 Integrated Biotherapeutic Vaccines, Inc. IMMUNOGENIC COMPOSITIONS CONTAINING POLYPEPTIDES DERIVED FROM LEUCOCIDINS LUKA AND LUKB OF STAPHYLOCOCCUS AUREUS
US20220241390A1 (en) * 2018-06-08 2022-08-04 Republic Of Korea (Animal And Plant Quarantine Agency) Vaccine composition comprising recombinant protein of staphylococcus aureus attenuated enterotoxin and cytotoxin
KR102061735B1 (ko) * 2018-06-08 2020-01-02 대한민국(농림축산식품부 농림축산검역본부장) 황색포도알균 약독화 장독소 및 세포독소 재조합 단백질을 포함하는 백신 조성물
TWI902669B (zh) 2018-07-24 2025-11-01 美商麥迪紐有限責任公司 抗金黃色葡萄球菌凝集因子a(clfa)之抗體
CN113164602A (zh) 2018-10-09 2021-07-23 免疫医疗有限责任公司 抗金黄色葡萄球菌抗体的组合
MX2021004114A (es) 2018-10-09 2021-07-16 Medimmune Llc Anticuerpos dirigidos contra leucotoxinas de staphylococcus aureus.
MX2021013833A (es) 2019-05-14 2022-03-17 Univ Chicago Metodos y composiciones que comprenden variantes de la proteina a de estafilococos (spa).
MX2022004061A (es) * 2019-10-02 2022-07-19 Janssen Vaccines & Prevention Bv Peptidos de estafilococo y metodos de uso.
KR20230091911A (ko) * 2020-09-28 2023-06-23 얀센 파마슈티칼즈, 인코포레이티드 변이체 스태필로코쿠스 아우레우스 LukA 및 LukB 폴리펩티드 및 백신 조성물
EP4313303A4 (en) * 2021-04-02 2025-02-26 Janssen Pharmaceuticals, Inc. VACCINE COMPOSITIONS FROM STAPHYLOCOCCUS AUREUS
ES3002583A1 (es) * 2023-09-05 2025-03-07 Lopez Juan Luis Recio Procedimiento de procesamiento de muestras biologicas para inmunoensayos

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US400A (en) 1837-09-25 Mode of causing puppet valves to work lights
US300A (en) 1837-07-29 Machine foe spinning woolen roving
RU2122862C1 (ru) * 1995-12-08 1998-12-10 Научно-исследовательский институт вакцин и сывороток им.И.И.Мечникова Бесклеточная антистафилококковая вакцина для лечения хронической стафилококковой инфекции
AU6033299A (en) 1998-09-14 2000-04-03 Nabi Compositions of beta-glucans and specific igiv
US20020061569A1 (en) 2000-03-21 2002-05-23 Robert Haselbeck Identification of essential genes in prokaryotes
US6849259B2 (en) 2000-06-16 2005-02-01 Symphogen A/S Polyclonal antibody composition for treating allergy
AT410798B (de) * 2001-01-26 2003-07-25 Cistem Biotechnologies Gmbh Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen
GB0107661D0 (en) * 2001-03-27 2001-05-16 Chiron Spa Staphylococcus aureus
CA2484604C (en) 2002-05-03 2011-08-02 Massachusetts Institute Of Technology .delta. 4,5 glycuronidase and uses thereof
TWI374892B (en) * 2005-06-13 2012-10-21 Glaxosmithkline Biolog Sa Use of panton-valentine leukocidin for treating and preventing staphylococcus infections
CN100485038C (zh) * 2005-09-13 2009-05-06 四川大学华西医院 小型化抗耐药金黄色葡萄球菌多肽及其应用与制备方法
WO2007100580A2 (en) * 2006-02-22 2007-09-07 The Texas A & M University System Antibodies recognizing a highly expressed putative antigen of ca-mrsa and methods of use
EP2043690A1 (en) * 2006-06-12 2009-04-08 Nabi Biopharmaceuticals Use of alpha-toxin for treating and preventing staphylococcus infections
CN101535811B (zh) * 2006-10-18 2016-05-04 生物梅里埃公司 用于体外诊断产pvl金黄色葡萄球菌的方法
GB0624340D0 (en) * 2006-12-06 2007-01-17 Nature Therapeutics Ltd Antimicrobial composition
EP2185190B1 (en) * 2007-08-31 2015-06-24 University Of Chicago Methods and compositions related to immunizing against staphylococcal lung diseases and conditions
EP2215231A4 (en) 2007-10-15 2010-12-01 Univ Queensland EXPRESSION SYSTEM FOR MODULATING AN IMMUNE RESPONSE
CN101182350A (zh) * 2007-11-02 2008-05-21 山东省农业科学院奶牛研究中心 金黄色葡萄球菌α-溶血素及其编码序列
WO2009111177A2 (en) * 2008-03-05 2009-09-11 Mount Sinai School Of Medicine Of New York University Compositions and methods comprising genetically enhanced obligate and facultative anaerobic bacteria for oncopathic cancer therapy
WO2009140236A2 (en) * 2008-05-12 2009-11-19 Strox Biopharmaceuticals, Llc Staphylococcus aureus-specific antibody preparations
WO2010098788A2 (en) 2008-08-25 2010-09-02 Amplimmune, Inc. Pd-i antagonists and methods for treating infectious disease
CN103002911B (zh) 2008-09-26 2015-08-26 昂考梅德药品有限公司 卷曲蛋白结合药剂及其应用
MX2011010735A (es) * 2009-04-14 2012-01-25 Novartis Ag Composiciones para inmunizacion contra staphylococcus aureus.
RU2677140C1 (ru) * 2010-05-05 2019-01-15 Нью-Йорк Юниверсити Лейкоцидины staphylococcus aureus, терапевтические композиции и их применение

Also Published As

Publication number Publication date
RU2644237C2 (ru) 2018-02-08
AU2016262661B2 (en) 2019-07-25
EP2566519A2 (en) 2013-03-13
IL274109A (en) 2020-06-30
IL274109B1 (en) 2025-08-01
EP3121191A1 (en) 2017-01-25
CA2798355A1 (en) 2011-11-10
AU2011247989C1 (en) 2015-05-14
JP7001661B2 (ja) 2022-02-21
ES2605476T3 (es) 2017-03-14
JP6031029B2 (ja) 2016-11-24
WO2011140337A3 (en) 2012-03-15
KR20190133290A (ko) 2019-12-02
KR101933226B1 (ko) 2018-12-28
KR102050078B1 (ko) 2019-11-28
AU2021236457A1 (en) 2021-10-14
CN103025352A (zh) 2013-04-03
US20230295248A1 (en) 2023-09-21
SI3444268T1 (sl) 2022-05-31
IL222874B (en) 2020-05-31
MY165618A (en) 2018-04-18
WO2011140337A2 (en) 2011-11-10
ZA202002470B (en) 2022-12-21
US11584782B2 (en) 2023-02-21
JP6253742B2 (ja) 2017-12-27
EP3444268A1 (en) 2019-02-20
ES2904314T3 (es) 2022-04-04
US20180099998A1 (en) 2018-04-12
IL222874A0 (en) 2012-12-31
JP2018076324A (ja) 2018-05-17
RU2677140C1 (ru) 2019-01-15
MX364642B (es) 2019-05-03
US20130095115A1 (en) 2013-04-18
RU2012152086A (ru) 2014-06-10
HRP20220068T1 (hr) 2022-04-15
EP3444268B1 (en) 2021-12-15
AU2015200901B2 (en) 2016-12-15
US20190330284A1 (en) 2019-10-31
JP2017048206A (ja) 2017-03-09
BR112012029521A2 (pt) 2018-03-06
MX386545B (es) 2025-03-19
EP2566519A4 (en) 2014-01-15
KR20180137612A (ko) 2018-12-27
AU2016262661A1 (en) 2016-12-08
AU2011247989B2 (en) 2014-11-27
JP6678634B2 (ja) 2020-04-08
HUE058787T2 (hu) 2022-09-28
ZA201208455B (en) 2016-07-27
US20110274693A1 (en) 2011-11-10
ZA201603107B (en) 2018-09-26
CN107286224A (zh) 2017-10-24
AU2015200901A1 (en) 2015-03-12
IL274109B2 (en) 2025-12-01
ZA201802995B (en) 2020-12-23
JP2013531620A (ja) 2013-08-08
US8431687B2 (en) 2013-04-30
RU2018146933A (ru) 2020-06-29
KR20130060230A (ko) 2013-06-07
MX2019005156A (es) 2019-08-05
AU2021236457B2 (en) 2024-05-02
MX2021003906A (es) 2021-09-30
EP2566519B1 (en) 2016-09-07
DK3444268T3 (da) 2022-01-31
US10316067B2 (en) 2019-06-11
CN103025352B (zh) 2017-07-11
CA2798355C (en) 2020-09-15
EP4015523A1 (en) 2022-06-22
JP2020055835A (ja) 2020-04-09
AU2019222824A1 (en) 2019-09-19
AU2011247989A1 (en) 2012-12-06
US9783582B2 (en) 2017-10-10
CA3088918A1 (en) 2011-11-10
PL3444268T3 (pl) 2022-04-19
MX2012012859A (es) 2013-03-20
EP3121191B1 (en) 2018-09-26

Similar Documents

Publication Publication Date Title
ZA202002470B (en) Staphylococcus aureus leukocidins, therapeutic compositions, and uses thereof
LT3202460T (lt) Arilmetoksi izoindolino dariniai ir kompozicijos, apimantys ir jų panaudojimo būdus
EP2611310A4 (en) ANTIMICROBIAL FORMULATION
EP2549993A4 (en) ANTIMICROBIAL COMPOSITIONS
BR112013011844A2 (pt) composições pesticidas agrícolas
EP2941128C0 (en) ANTIMICROBIAL COMPOSITIONS
LT3061454T (lt) Paraziticidinės peroralinės veterinarinės kompozicijos, apimančios sistemiškai veikiančius veikliuosius agentus, būdai ir jų panaudojimas
EP2725900A4 (en) ANTIMICROBIAL COMPOSITION
EP2558132A4 (en) ANTIMICROBIAL GEL
EP2911507A4 (en) AGRICULTURAL PESTICIDE COMPOSITIONS
PL3043769T3 (pl) Hipertoniczne, terapeutyczne kompozycje przeciwdrobnoustrojowe
EP2934121A4 (en) IMPROVED ANTIMICROBIAL COMPOSITIONS
EP2755476A4 (en) AGRICULTURAL PESTICIDE COMPOSITIONS
PL2547361T3 (pl) Bakteryjne składniki szczepionek pochodzące ze staphylococcus aureus i ich zastosowania
EP2627172A4 (en) ANTIMICROBIAL COMPOSITION
BR112014005254A2 (pt) composições antimicrobianas e usos das mesmas
BR112012013182A2 (pt) composições tópicas germicidas
IL225495B (en) Antimicrobial protein
EP2605654A4 (en) ANTIMICROBIAL COMPOSITIONS
EP2593134A4 (en) PROTECTION BASED ON THE STAPHYLOCOCCUS AUREUS PROTEIN SA2412
HK1182925A (en) Staphylococcus aureus leukocidins, therapeutic compositions, and uses thereof
FI20105517A0 (fi) Antimikrobinen koostumus
DK2558132T3 (da) Antimikrobiel gel
TH149336B (th) "องค์ประกอบต้านจุลชีพ"
TH149319B (th) "องค์ประกอบต้านจุลชีพ"