LT4989B - Apolipoproteino b-100 epitopo mimeziniai peptidai, jų konkatemerai ir modifikuotieji peptidai, ir juos turinti vakcinos kompozicija - Google Patents

Apolipoproteino b-100 epitopo mimeziniai peptidai, jų konkatemerai ir modifikuotieji peptidai, ir juos turinti vakcinos kompozicija Download PDF

Info

Publication number
LT4989B
LT4989B LT2002051A LT2002051A LT4989B LT 4989 B LT4989 B LT 4989B LT 2002051 A LT2002051 A LT 2002051A LT 2002051 A LT2002051 A LT 2002051A LT 4989 B LT4989 B LT 4989B
Authority
LT
Lithuania
Prior art keywords
peptide
mimetic
concatemer
peptides
apoliprotein
Prior art date
Application number
LT2002051A
Other languages
English (en)
Lithuanian (lt)
Other versions
LT2002051A (en
Inventor
Hyo Joon Kim
Original Assignee
Hyo Joon Kim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR10-2001-0054005A external-priority patent/KR100472841B1/ko
Application filed by Hyo Joon Kim filed Critical Hyo Joon Kim
Publication of LT2002051A publication Critical patent/LT2002051A/xx
Publication of LT4989B publication Critical patent/LT4989B/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775Apolipopeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
LT2002051A 2000-09-04 2002-04-29 Apolipoproteino b-100 epitopo mimeziniai peptidai, jų konkatemerai ir modifikuotieji peptidai, ir juos turinti vakcinos kompozicija LT4989B (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20000052055 2000-09-04
KR10-2001-0054005A KR100472841B1 (ko) 2000-09-04 2001-09-04 아포지단백질 비-100의 에피토프에 대한 모조 펩타이드,그들의 연쇄물 또는 변형체와 이들을 함유하는 백신 조성물

Publications (2)

Publication Number Publication Date
LT2002051A LT2002051A (en) 2002-09-25
LT4989B true LT4989B (lt) 2003-01-27

Family

ID=26638363

Family Applications (1)

Application Number Title Priority Date Filing Date
LT2002051A LT4989B (lt) 2000-09-04 2002-04-29 Apolipoproteino b-100 epitopo mimeziniai peptidai, jų konkatemerai ir modifikuotieji peptidai, ir juos turinti vakcinos kompozicija

Country Status (18)

Country Link
US (1) US6825318B2 (cs)
EP (1) EP1315517B1 (cs)
JP (1) JP2004508029A (cs)
CN (1) CN1231262C (cs)
AU (1) AU8628601A (cs)
BG (1) BG106655A (cs)
BR (1) BR0107175A (cs)
CA (1) CA2389739A1 (cs)
CZ (1) CZ20021571A3 (cs)
EE (1) EE200200238A (cs)
HU (1) HUP0203251A2 (cs)
IL (1) IL149379A0 (cs)
LT (1) LT4989B (cs)
MX (1) MXPA02004505A (cs)
NO (1) NO20022147L (cs)
RU (1) RU2313536C2 (cs)
SK (1) SK6312002A3 (cs)
WO (1) WO2002020040A1 (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL379196A1 (pl) * 2003-06-11 2006-07-24 Schering Aktiengesellschaft Nowe zmodyfikowane cząsteczki koryny posiadające substytut sekwencji aktywacji i ich zastosowanie
KR100639397B1 (ko) * 2004-03-18 2006-10-26 (주)에스제이바이오메드 항비만용 면역원성 하이브리드 폴리펩타이드 및 이를포함하는 항비만 백신 조성물
US20070054298A1 (en) * 2005-08-12 2007-03-08 Kent Kirshenbaum Methods for enzyme-mediated coupling of oligomers
WO2007075335A2 (en) * 2005-12-16 2007-07-05 The Regents Of The University Of California Modulation of in utero immune programming
US8961982B2 (en) * 2005-12-16 2015-02-24 The Regents Of The University Of California Modulation of developmental immune programming and protection against cardiovascular disease, diabetes, infectious diseases, and cancer
RU2418005C2 (ru) * 2006-09-25 2011-05-10 ЭсДжей БАЙОМЕД ИНК. Иммуногенные гибридные полипептиды против ожирения и композиция вакцин против ожирения, содержащая эти полипептиды
CN103520713B (zh) * 2013-10-16 2015-10-28 西北农林科技大学 一种ApoB100酵母重组疫苗及其制备方法和应用
EP3463416A1 (en) 2016-05-31 2019-04-10 CardioVax, LLC Methods for diagnosing and treating systemic lupus erythematosus
US10858422B2 (en) 2016-05-31 2020-12-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3215310A1 (de) * 1982-04-23 1983-10-27 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur bestimmung der low density lipoproteine (ldl) und reagenz zu seiner durchfuehrung
US6309853B1 (en) * 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
CA2283474A1 (en) * 1997-03-04 1998-09-11 Bio-Technology General Corp. Isolation of tissue specific peptide ligands and their use for targeting pharmaceuticals to organs
AU2801299A (en) * 1998-03-04 1999-09-20 Bio-Technology General Corporation Isolation of tissue specific peptide ligands and their use for targeting pharmaceuticals to organs
EP1267908B1 (en) * 2000-03-03 2004-05-06 GlaxoSmithKline Biologicals S.A. Vaccine for the treatment of atherosclerosis

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
ALVING CR, WASSEF NM, POTTER M.: "Antibodies to cholesterol: biological implications of antibodies to lipids", CURR TOP MICROBIOL IMMUNOL., 1996, pages 181 - 186, XP002923267
BRECHER G, WAXLER SH.: "Obesity in albino mice due to single injections of goldthioglucose", PROC SOC EXP BIOL MED., 1949, pages 498 - 501
BROWN MS, GOLDSTEIN JL: "Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis", ANNU REV BIOCHEM., 1983, pages 223 - 261
CARL R. ALVING ET AL.: "Immunization with cholesterol-rich liposomes induces anti-cholesterol antibodies and reduces diet-induced hypercholesterolemia and plaque formation", JOURNAL OF LABORATORY AND CLINICAL MEDICINE, 1996, pages 40 - 49, XP001095396, DOI: doi:10.1016/S0022-2143(96)90164-X
CARL R. ALVING ET AL.: "Naturally occurring autoantibodies to cholesterol in humans", BIOCHEMICAL SOCIETY TRANSACTIONS, 1989, pages 637 - 639
DALUM I ET AL.: "Induction of cross-reactive antibodies against a self protein by immunization with a modified self protein containing a foreign T helper epitope", MOL IMMUNOL., 1997, pages 1113 - 1120, XP002920190, DOI: doi:10.1016/S0161-5890(97)00147-8
JM BAILEY: "Cholesterol vaccines", SCIENCE, 1994, pages 1067 - 1068, XP002310090
W PALINSKI ET AL.: "Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis", PROC NATL ACAD SCI USA., 1995, pages 821 - 825, XP002951783, DOI: doi:10.1073/pnas.92.3.821

Also Published As

Publication number Publication date
EP1315517B1 (en) 2010-10-20
CA2389739A1 (en) 2002-03-14
SK6312002A3 (en) 2002-09-10
JP2004508029A (ja) 2004-03-18
BR0107175A (pt) 2002-07-02
RU2003109439A (ru) 2004-07-20
BG106655A (bg) 2004-08-31
CN1392798A (zh) 2003-01-22
US6825318B2 (en) 2004-11-30
US20030211997A1 (en) 2003-11-13
MXPA02004505A (es) 2004-09-10
CZ20021571A3 (cs) 2002-09-11
IL149379A0 (en) 2002-11-10
WO2002020040A1 (en) 2002-03-14
EP1315517A1 (en) 2003-06-04
LT2002051A (en) 2002-09-25
NO20022147D0 (no) 2002-05-03
AU8628601A (en) 2002-03-22
HUP0203251A2 (hu) 2003-01-28
NO20022147L (no) 2002-05-03
CN1231262C (zh) 2005-12-14
RU2313536C2 (ru) 2007-12-27
EE200200238A (et) 2003-06-16
EP1315517A4 (en) 2005-02-09

Similar Documents

Publication Publication Date Title
US6410022B1 (en) Modulation of cholesteryl ester transfer protein (CETP) activity
US6699973B1 (en) Antibodies to peptides that target GIT receptors and related methods
LT4989B (lt) Apolipoproteino b-100 epitopo mimeziniai peptidai, jų konkatemerai ir modifikuotieji peptidai, ir juos turinti vakcinos kompozicija
EP0672136B1 (en) Polypeptides, derived from endonexin 2, having hepatitis b virus receptor activity and their use in diagnostic and pharmaceutical compositions
KR100956893B1 (ko) 항비만용 면역원성 하이브리드 폴리펩타이드 및 이를포함하는 항비만 백신 조성물
TW200911282A (en) Pharmaceutical compound
AU2004262472A1 (en) Targeted therapeutic vaccine against P-glycoprotein 170 for inhibiting multi-drug resistance in the treatment of cancers
JP2010504094A5 (cs)
KR100639397B1 (ko) 항비만용 면역원성 하이브리드 폴리펩타이드 및 이를포함하는 항비만 백신 조성물
KR100472841B1 (ko) 아포지단백질 비-100의 에피토프에 대한 모조 펩타이드,그들의 연쇄물 또는 변형체와 이들을 함유하는 백신 조성물
JP2003511061A (ja) 変更された化学結合体化特性を有するab5毒素bサブユニット変異体
AU2007200834B2 (en) Mimetic peptides for epitope of apolipoprotein B-100, concatemer and modified peptides thereof, and the vaccine composition comprising the same
US5871739A (en) Pharmaceutical composition
HK1050857A (en) Mimetic peptides for epitope of apolipoprotein b-100, concatemer and modified peptides thereof, and the vaccine composition comprising the same
JP2000505645A (ja) カルシウム結合プロテオリピド組成物および方法
HK1026119A (en) Mammalian nonhuman transgenic animal having a constitutive or inducible expression of the human endonexin ii gene or its muteins or its fragments

Legal Events

Date Code Title Description
MM9A Lapsed patents

Effective date: 20030904