LT5215B - Matricines metalproteinazes inhibuojanti kompozicija neoplazinėms ligoms gydyti - Google Patents

Matricines metalproteinazes inhibuojanti kompozicija neoplazinėms ligoms gydyti Download PDF

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Publication number
LT5215B
LT5215B LT2004074A LT2004074A LT5215B LT 5215 B LT5215 B LT 5215B LT 2004074 A LT2004074 A LT 2004074A LT 2004074 A LT2004074 A LT 2004074A LT 5215 B LT5215 B LT 5215B
Authority
LT
Lithuania
Prior art keywords
composition
matrix metalloproteinases
matrix
diseases
ascorbic acid
Prior art date
Application number
LT2004074A
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English (en)
Lithuanian (lt)
Other versions
LT2004074A (en
Inventor
Matthias Rath
Shrirang Netke
Vadim Ivanov
Waheed Roomi
Aleksandra Niedzwiecki
Original Assignee
Matthias Rath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matthias Rath filed Critical Matthias Rath
Publication of LT2004074A publication Critical patent/LT2004074A/xx
Publication of LT5215B publication Critical patent/LT5215B/lt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
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    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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    • A61P31/12—Antivirals
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    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Biotechnology (AREA)
  • Vascular Medicine (AREA)
  • AIDS & HIV (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
LT2004074A 2002-01-08 2004-08-05 Matricines metalproteinazes inhibuojanti kompozicija neoplazinėms ligoms gydyti LT5215B (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/041,427 US6939860B2 (en) 2002-01-08 2002-01-08 Composition and method for treatment of neoplastic diseases associated with elevated matrix metalloproteinase activities using catechin compounds

Publications (2)

Publication Number Publication Date
LT2004074A LT2004074A (en) 2004-12-27
LT5215B true LT5215B (lt) 2005-05-25

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LT2004074A LT5215B (lt) 2002-01-08 2004-08-05 Matricines metalproteinazes inhibuojanti kompozicija neoplazinėms ligoms gydyti

Country Status (29)

Country Link
US (3) US6939860B2 (de)
EP (1) EP1463498B1 (de)
JP (1) JP4144800B2 (de)
KR (1) KR20050005408A (de)
CN (1) CN1612731A (de)
AT (1) ATE439833T1 (de)
AU (2) AU2002244690A1 (de)
BR (1) BR0208052A (de)
CA (1) CA2469162A1 (de)
CZ (1) CZ2004853A3 (de)
DE (1) DE60233433D1 (de)
EE (1) EE200400031A (de)
ES (1) ES2332126T3 (de)
HR (1) HRP20040705A2 (de)
HU (1) HUP0402421A3 (de)
IL (1) IL162384A0 (de)
LT (1) LT5215B (de)
LV (1) LV13249B (de)
MX (1) MXPA04006627A (de)
NO (1) NO20033949L (de)
NZ (1) NZ533353A (de)
PL (1) PL371205A1 (de)
RU (1) RU2284185C2 (de)
SI (1) SI21871A (de)
SK (1) SK2772004A3 (de)
TR (1) TR200401669T1 (de)
UA (1) UA78979C2 (de)
WO (1) WO2003057211A1 (de)
ZA (1) ZA200404915B (de)

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US20070265211A1 (en) * 2006-05-12 2007-11-15 Matthias Rath Novel composition and method effective in inhibiting the atherogenic process
US20100055205A1 (en) * 2008-08-29 2010-03-04 Kristina Mains Functional consumable compositions for promoting skin health and methods for using the same
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MX2011004678A (es) 2008-11-04 2011-10-11 Vymedic Llc Formulaciones complementarias antivirales.
JP4786000B2 (ja) * 2009-10-16 2011-10-05 株式会社カネカ 還元型補酵素q10の製造方法、安定化方法及びそれを含有する組成物
ES2694582T3 (es) * 2011-01-31 2018-12-21 Lucolas-M.D. Ltd. Combinaciones de inhibidores de aromatasa y antioxidantes
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CN104096058A (zh) * 2014-07-02 2014-10-15 胥玲 一种治疗扩张型心肌病的中药药丸
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UA78979C2 (en) 2007-05-10
SK2772004A3 (en) 2004-12-01
RU2284185C2 (ru) 2006-09-27
NO20033949D0 (no) 2003-09-05
ZA200404915B (en) 2006-07-26
ES2332126T3 (es) 2010-01-27
US20050032715A1 (en) 2005-02-10
EP1463498A1 (de) 2004-10-06
US20030130201A1 (en) 2003-07-10
JP4144800B2 (ja) 2008-09-03
DE60233433D1 (de) 2009-10-01
TR200401669T1 (tr) 2007-01-22
AU2008203157A1 (en) 2008-08-07
CZ2004853A3 (cs) 2004-12-15
EP1463498B1 (de) 2009-08-19
LT2004074A (en) 2004-12-27
CN1612731A (zh) 2005-05-04
NZ533353A (en) 2007-04-27
JP2005513166A (ja) 2005-05-12
CA2469162A1 (en) 2003-07-17
RU2004124047A (ru) 2005-04-20
LV13249B (en) 2005-07-20
BR0208052A (pt) 2005-01-04
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IL162384A0 (en) 2005-11-20
MXPA04006627A (es) 2004-11-10
WO2003057211A1 (en) 2003-07-17
US20050281794A1 (en) 2005-12-22
HUP0402421A2 (hu) 2005-07-28
ATE439833T1 (de) 2009-09-15
KR20050005408A (ko) 2005-01-13
EE200400031A (et) 2004-04-15
PL371205A1 (en) 2005-06-13
HRP20040705A2 (en) 2004-10-31
SI21871A (sl) 2006-04-30
US6939860B2 (en) 2005-09-06
AU2002244690A1 (en) 2003-07-24
NO20033949L (no) 2003-11-04

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