LTC2365972I2 - ATF surišančios kasetės transporterių moduliatoriai - Google Patents

ATF surišančios kasetės transporterių moduliatoriai

Info

Publication number: LTC2365972I2
Authority: LT; Lithuania
Prior art keywords: cartridge conveyor; binding cartridge; modulators; atf binding; atf
Prior art date: 2008-11-06

Application number

Other languages

Original Assignee

Vertex Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-11-06

Filing date

2019-03-21

Publication date

2019-12-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40933810&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LTC2365972(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2019-03-21 Application filed by Vertex Pharma filed Critical Vertex Pharma

2019-04-10 Publication of LTPA2019505I1 publication Critical patent/LTPA2019505I1/lt

2019-12-10 Publication of LTC2365972I2 publication Critical patent/LTC2365972I2/lt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Neurology (AREA)
Endocrinology (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Obesity (AREA)
Ophthalmology & Optometry (AREA)
Psychology (AREA)
Dermatology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Emergency Medicine (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

LTPA2019505 2008-11-06 2019-03-21 ATF surišančios kasetės transporterių moduliatoriai LTC2365972I2 (lt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US11215208P	2008-11-06	2008-11-06
US11214508P	2008-11-06	2008-11-06
PCT/US2008/012689 WO2010053471A1 (en)	2008-11-06	2008-11-12	Modulators of atp-binding cassette transporters

Publications (2)

Publication Number	Publication Date
LTPA2019505I1 LTPA2019505I1 (lt)	2019-04-10
LTC2365972I2 true LTC2365972I2 (lt)	2019-12-10

Family

ID=40933810

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LTPA2019505 LTC2365972I2 (lt)	2008-11-06	2019-03-21	ATF surišančios kasetės transporterių moduliatoriai

Country Status (31)

Country	Link
EP (2)	EP2365972B1 (lt)
JP (4)	JP5600322B2 (lt)
KR (3)	KR20160013251A (lt)
CN (2)	CN108117546A (lt)
AU (1)	AU2008363828B2 (lt)
BR (1)	BRPI0823228B8 (lt)
CA (1)	CA2742821C (lt)
CL (1)	CL2011001027A1 (lt)
CY (2)	CY1116067T1 (lt)
DK (1)	DK2365972T3 (lt)
ES (1)	ES2532753T3 (lt)
FR (1)	FR19C1017I2 (lt)
HK (1)	HK1216526A1 (lt)
HR (1)	HRP20150288T1 (lt)
HU (1)	HUS1900015I1 (lt)
IL (3)	IL212737A (lt)
LT (1)	LTC2365972I2 (lt)
LU (1)	LUC00110I2 (lt)
ME (1)	ME02105B (lt)
MX (2)	MX2011004832A (lt)
NL (1)	NL300984I9 (lt)
NO (1)	NO2019015I1 (lt)
NZ (2)	NZ609962A (lt)
PL (1)	PL2365972T3 (lt)
PT (1)	PT2365972E (lt)
RS (1)	RS53868B1 (lt)
RU (1)	RU2013157877A (lt)
SI (1)	SI2365972T1 (lt)
UA (1)	UA121188C2 (lt)
WO (1)	WO2010053471A1 (lt)
ZA (1)	ZA201103883B (lt)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
LT2502911T (lt)	2004-06-24	2017-09-11	Vertex Pharmaceuticals Incorporated	Atp surišančios kasetės transporterių moduliatoriai
EP1945632B1 (en)	2005-11-08	2013-09-18	Vertex Pharmaceuticals Incorporated	Heterocyclic modulators of atp-binding cassette transporters
WO2007079139A2 (en)	2005-12-28	2007-07-12	Vertex Pharmaceuticals, Inc.	Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
US10022352B2 (en)	2006-04-07	2018-07-17	Vertex Pharmaceuticals Incorporated	Modulators of ATP-binding cassette transporters
NZ571803A (en)	2006-04-07	2011-12-22	Vertex Pharma	Amide indole derivatives as modulators of ATP-binding cassette transporters
US7645789B2 (en)	2006-04-07	2010-01-12	Vertex Pharmaceuticals Incorporated	Indole derivatives as CFTR modulators
USRE50453E1 (en)	2006-04-07	2025-06-10	Vertex Pharmaceuticals Incorporated	Indole derivatives as CFTR modulators
US8563573B2 (en)	2007-11-02	2013-10-22	Vertex Pharmaceuticals Incorporated	Azaindole derivatives as CFTR modulators
US8969386B2 (en)	2007-05-09	2015-03-03	Vertex Pharmaceuticals Incorporated	Modulators of CFTR
EP2639224B1 (en)	2007-12-07	2016-08-24	Vertex Pharmaceuticals Incorporated	Process for producing cycloalkylcarboxiamido-pyridine benzoic acids
SI2225230T1 (sl)	2007-12-07	2017-03-31	Vertex Pharmaceuticals Incorporated	Trdne oblike 3-(6-(1-2,2-difluorobenzo(d)(1,3)dioxol-5-il)ciklopropan- karboksamido)-3-metilpiridin-2-il) benzojske kisline
NZ720282A (en)	2008-02-28	2017-12-22	Vertex Pharma	Heteroaryl derivatives as cftr modulators
US12458635B2 (en)	2008-08-13	2025-11-04	Vertex Pharmaceuticals Incorporated	Pharmaceutical composition and administrations thereof
US20100074949A1 (en)	2008-08-13	2010-03-25	William Rowe	Pharmaceutical composition and administration thereof
EP2365972B1 (en) *	2008-11-06	2014-12-17	Vertex Pharmaceuticals Incorporated	Modulators of atp-binding cassette transporters
UA104876C2 (uk) *	2008-11-06	2014-03-25	Вертекс Фармасьютікалз Інкорпорейтед	Модулятори atф-зв'язувальних касетних транспортерів
SI2408750T1 (sl)	2009-03-20	2015-11-30	Vertex Pharmaceuticals Incorporated	Postopek za izdelavo modulatorjev cistično-fibroznega transmembranskega regulatorja prevodnosti
US8802868B2 (en)	2010-03-25	2014-08-12	Vertex Pharmaceuticals Incorporated	Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide
US20110251253A1 (en) *	2010-03-25	2011-10-13	Vertex Pharmaceuticals Incorporated	Solid forms of (r)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1h-indol-5-yl) cyclopropanecarboxamide
HRP20211752T1 (hr)	2010-04-07	2022-02-18	Vertex Pharmaceuticals Incorporated	Farmaceutski pripravci 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioksol-5-il)ciklopropankarboksamido)-3-metilpiridin-2-il)benzojeve kiseline i njihova primjena
AU2011242454A1 (en) *	2010-04-22	2012-11-08	Vertex Pharmaceuticals Incorporated	Pharmaceutical compositions and administrations thereof
NZ603044A (en) *	2010-04-22	2015-08-28	Vertex Pharma	Pharmaceutical compositions comprising cftr modulators and administrations thereof
ES2608474T3 (es)	2010-04-22	2017-04-11	Vertex Pharmaceuticals Incorporated	Proceso de producción de compuestos indol cycloalkylcarboxamido
CA2796642A1 (en) *	2010-04-22	2011-10-27	Vertex Pharmaceuticals Incorporated	Pharmaceutical compositions and administrations thereof
CA2808501A1 (en) *	2010-08-23	2012-03-01	Vertex Pharmaceuticals Incorporated	Pharmaceutical composition of (r)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihydroxy propyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1h-indol-5-yl) cyclopropanecarboxamide and administration therof
IN2014KN00885A (lt) *	2011-11-08	2015-10-02	Vertex Pharma
WO2013112804A1 (en)	2012-01-25	2013-08-01	Vertex Pharmaceuticals Incorporated	Formulations of 3-(6-(1-(2.2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
EP2819670A1 (en)	2012-02-27	2015-01-07	Vertex Pharmaceuticals Incorporated	Pharmaceutical composition and administration thereof
WO2014014841A1 (en)	2012-07-16	2014-01-23	Vertex Pharmaceuticals Incorporated	Pharmaceutical compositions of (r)-1-(2,2-diflurorbenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1h-indol-5-yl) cyclopropanecarboxamide and administration thereof
EP2970468B1 (en)	2013-03-13	2021-07-07	Novartis AG	Notch2 binding molecules for treating respiratory diseases
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Publication number	Publication date
CN108117546A (zh)	2018-06-05
HK1216526A1 (en)	2016-11-18
ZA201103883B (en)	2012-02-29
AU2008363828B2 (en)	2016-09-08
JP2016147887A (ja)	2016-08-18
NZ609962A (en)	2014-11-28
NZ592694A (en)	2013-05-31
CA2742821C (en)	2018-10-23
CY2019023I2 (el)	2019-11-27
MX357497B (es)	2018-07-11
JP5600322B2 (ja)	2014-10-01
KR20150036819A (ko)	2015-04-07
RS53868B1 (sr)	2015-08-31
CA2742821A1 (en)	2010-05-14
CN102272127A (zh)	2011-12-07
DK2365972T3 (en)	2015-01-19
JP2014208719A (ja)	2014-11-06
KR20110082188A (ko)	2011-07-18
NL300984I9 (nl)	2019-05-15
ES2532753T3 (es)	2015-03-31
KR101587389B1 (ko)	2016-01-28
IL239713A (en)	2017-10-31
CY1116067T1 (el)	2017-02-08
EP2365972A1 (en)	2011-09-21
CL2011001027A1 (es)	2012-03-02
IL212737A (en)	2014-08-31
IL212737A0 (en)	2011-07-31
JP2012507580A (ja)	2012-03-29
HRP20150288T1 (hr)	2015-04-24
WO2010053471A8 (en)	2011-09-22
UA121188C2 (uk)	2020-04-27
EP2365972B1 (en)	2014-12-17
LTPA2019505I1 (lt)	2019-04-10
PL2365972T3 (pl)	2015-05-29
CY2019023I1 (el)	2019-11-27
LUC00110I1 (lt)	2019-03-25
HUS1900015I1 (hu)	2019-05-28
JP5728611B2 (ja)	2015-06-03
RU2013157877A (ru)	2015-06-27
FR19C1017I1 (fr)	2019-05-03
RU2011122461A (ru)	2012-12-20
IL239713A0 (en)	2015-08-31
EP2940016A1 (en)	2015-11-04
NO2019015I1 (no)	2019-04-04
SI2365972T1 (sl)	2015-04-30
IL233837A (en)	2015-07-30
JP5905620B2 (ja)	2016-04-20
WO2010053471A1 (en)	2010-05-14
IL233837A0 (en)	2014-09-30
PT2365972E (pt)	2015-03-31
BRPI0823228B1 (pt)	2020-10-20
FR19C1017I2 (fr)	2019-07-19
KR20160013251A (ko)	2016-02-03
LUC00110I2 (lt)	2020-07-10
JP2015127345A (ja)	2015-07-09
ME02105B (me)	2015-10-20
KR101559963B1 (ko)	2015-10-26
RU2512682C2 (ru)	2014-04-10
BRPI0823228A2 (pt)	2016-10-11
NL300984I2 (nl)	2019-05-02
BRPI0823228B8 (pt)	2021-05-25
HK1162477A1 (en)	2012-08-31
MX2011004832A (es)	2011-07-28
AU2008363828A1 (en)	2010-05-14

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BRPI0918734A2 (pt)	2015-12-01	material polimérico
UA19086S (uk)	2009-06-25	Чорнильний картридж
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