LTIP839A - Kietos farmacinės dozuotos vaistų formos su memantinu, turinčios prailgintą dviejų stadijų atpalaidavimo profilį, ir jų gavimas - Google Patents

Kietos farmacinės dozuotos vaistų formos su memantinu, turinčios prailgintą dviejų stadijų atpalaidavimo profilį, ir jų gavimas

Info

Publication number
LTIP839A
LTIP839A LTIP839A LTIP839A LTIP839A LT IP839 A LTIP839 A LT IP839A LT IP839 A LTIP839 A LT IP839A LT IP839 A LTIP839 A LT IP839A LT IP839 A LTIP839 A LT IP839A
Authority
LT
Lithuania
Prior art keywords
memantine
solid pharmaceutical
extended
production
dosage forms
Prior art date
Application number
LTIP839A
Other languages
English (en)
Inventor
Eberhard Nurnberg
Erhard Seiller
Stefan Ritsert
Original Assignee
Merz Pharma Gmbh & Co. Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co. Kgaa filed Critical Merz Pharma Gmbh & Co. Kgaa
Publication of LTIP839A publication Critical patent/LTIP839A/lt
Publication of LT3201B publication Critical patent/LT3201B/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2063Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1658Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Šis išradimas apima kietas farmacines kompozicijas dozuotoje formoje, turinčias aktyvų ingredientą arba pagrindą, ypač memantiną, kurios įgyvendinta prailgintą dviejų fazių vaisto išskyrimą, ir kurios yra charakterizuojamos buvimu matricoje dviejų - vandenyje tirpios ir vandenyje netirpios kazeino druskos, ypač natrio ir kalcio kazeinatų plačiose proporcijų ribose , o jų bendras kiekis kompozicijoje yra tarp 5 ir 98 masės %, ir jų gavimo būdą.
LTIP839A 1992-08-04 1993-08-04 Memantine-containing solid pharmaceutical dosage forms having an extended two-stage release profile and production thereof LT3201B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4225730A DE4225730C2 (de) 1992-08-04 1992-08-04 Verfahren zur Herstellung von festen Arzneiformkörpern mit protrahierter 2-Stufen-Freisetzung

Publications (2)

Publication Number Publication Date
LTIP839A true LTIP839A (lt) 1994-08-25
LT3201B LT3201B (en) 1995-03-27

Family

ID=6464804

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP839A LT3201B (en) 1992-08-04 1993-08-04 Memantine-containing solid pharmaceutical dosage forms having an extended two-stage release profile and production thereof

Country Status (17)

Country Link
US (1) US5382601A (lt)
EP (1) EP0582186B1 (lt)
JP (1) JP3560244B2 (lt)
CN (1) CN1086708A (lt)
AT (1) ATE176866T1 (lt)
AU (1) AU669731B2 (lt)
CA (1) CA2141691C (lt)
DE (2) DE4225730C2 (lt)
DK (1) DK0582186T3 (lt)
ES (1) ES2128369T3 (lt)
GR (1) GR3030227T3 (lt)
IL (1) IL106580A (lt)
LT (1) LT3201B (lt)
LV (1) LV10182B (lt)
MX (1) MX9304675A (lt)
WO (1) WO1994003158A1 (lt)
ZA (1) ZA935614B (lt)

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US6294583B1 (en) 1998-01-13 2001-09-25 Synchroneuron, Llc Methods of treating tardive dyskinesia and other movement disorders
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US8481565B2 (en) * 2004-12-27 2013-07-09 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
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JP5666087B2 (ja) 2005-04-06 2015-02-12 アダマス・ファーマシューティカルズ・インコーポレーテッド Cns関連疾患の治療のための方法及び組成物
JP5597343B2 (ja) * 2005-04-28 2014-10-01 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗痴呆薬を含有する組成物
US20060270742A1 (en) * 2005-05-02 2006-11-30 Jane Staunton Compositions and methods for the treatment of neurodegenerative diseases
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WO2009084017A2 (en) 2007-10-10 2009-07-09 Rubicon Research Private Limited Taste-masked orally disintegrating tablets of memantine hydrochloride
US20090247644A1 (en) * 2008-03-28 2009-10-01 Forest Laboratories Holdings Limited Memantine formulations
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AU2010325960C1 (en) 2009-12-02 2015-08-06 Adamas Pharma, Llc Amantadine compositions and methods of use
EP2363119A1 (fr) * 2010-03-05 2011-09-07 Centre Hospitalier Universitaire d'Angers Nouvelle composition pharmaceutique utile pour le traitement des personnes affectées par des maladies neurodégénératives ou neurovasculaires
US20140004189A1 (en) 2011-01-25 2014-01-02 Cadila Healthcare Limited Modified release pharmaceutical compositions memantine
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Also Published As

Publication number Publication date
CN1086708A (zh) 1994-05-18
EP0582186B1 (de) 1999-02-24
US5382601A (en) 1995-01-17
EP0582186A1 (de) 1994-02-09
IL106580A0 (en) 1993-12-08
CA2141691A1 (en) 1994-02-17
JPH07509479A (ja) 1995-10-19
LT3201B (en) 1995-03-27
DE4225730C2 (de) 2003-04-30
WO1994003158A1 (en) 1994-02-17
AU669731B2 (en) 1996-06-20
DK0582186T3 (da) 1999-09-27
IL106580A (en) 1998-02-08
DE59309388D1 (de) 1999-04-01
LV10182A (lv) 1994-10-20
ATE176866T1 (de) 1999-03-15
ZA935614B (en) 1995-02-03
LV10182B (en) 1995-04-20
DE4225730A1 (de) 1994-02-10
MX9304675A (es) 1994-03-31
GR3030227T3 (en) 1999-08-31
AU4706993A (en) 1994-03-03
ES2128369T3 (es) 1999-05-16
JP3560244B2 (ja) 2004-09-02
CA2141691C (en) 2002-04-09

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Legal Events

Date Code Title Description
TK9A Rectifications: patents

Free format text: MERZ + CO. GMBH & CO., ECKENHEIMER LANDSTRASSE 100-104, D-6000 FRANKFURT AM MAIN 1, DE, 19951128

PD9A Change of patent owner

Owner name: MERZ PHARMA GMBH & CO. KGAA,DE

Effective date: 20021017

MK9A Expiry of a patent

Effective date: 20130804