LU81352A1 - Medicament constitue par un derive de cyclopentyl-addehyde et composition le renfermant - Google Patents

Medicament constitue par un derive de cyclopentyl-addehyde et composition le renfermant Download PDF

Info

Publication number: LU81352A1
Authority: LU; Luxembourg
Prior art keywords: cyclopentyl; cis; trans; formula; product
Prior art date: 1978-06-03

Application number

LU81352A

Other languages

English (en)

French (fr)

Inventor

J Lemoine

J Debat

J Riffaud

Original Assignee

Inst Rech Chim Biolog

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-06-03

Filing date

1979-06-01

Publication date

1980-01-22

1979-06-01 Application filed by Inst Rech Chim Biolog filed Critical Inst Rech Chim Biolog

1980-01-22 Publication of LU81352A1 publication Critical patent/LU81352A1/fr

Links

239000000203 mixture Substances 0.000 title claims abstract description 12
VELDYOPRLMJFIK-UHFFFAOYSA-N cyclopentanecarbaldehyde Chemical class O=CC1CCCC1 VELDYOPRLMJFIK-UHFFFAOYSA-N 0.000 claims abstract description 10
230000001225 therapeutic effect Effects 0.000 claims abstract description 5
125000000896 monocarboxylic acid group Chemical group 0.000 claims abstract description 4
238000002560 therapeutic procedure Methods 0.000 claims abstract description 3
239000004480 active ingredient Substances 0.000 claims description 4
239000003814 drug Substances 0.000 claims description 4
239000000546 pharmaceutical excipient Substances 0.000 claims description 3
208000035285 Allergic Seasonal Rhinitis Diseases 0.000 claims description 2
208000035473 Communicable disease Diseases 0.000 claims description 2
206010020751 Hypersensitivity Diseases 0.000 claims description 2
230000007815 allergy Effects 0.000 claims description 2
125000000008 (C1-C10) alkyl group Chemical group 0.000 claims 1
206010061218 Inflammation Diseases 0.000 claims 1
208000002193 Pain Diseases 0.000 claims 1
150000001299 aldehydes Chemical class 0.000 claims 1
230000004054 inflammatory process Effects 0.000 claims 1
229940126601 medicinal product Drugs 0.000 claims 1
230000036407 pain Effects 0.000 claims 1
125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract description 5
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract description 2
CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 12
NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 description 12
241001465754 Metazoa Species 0.000 description 12
239000000443 aerosol Substances 0.000 description 10
150000001875 compounds Chemical class 0.000 description 10
229960001340 histamine Drugs 0.000 description 6
VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 6
108010058846 Ovalbumin Proteins 0.000 description 5
241000191967 Staphylococcus aureus Species 0.000 description 5
241000083821 Teucrium marum Species 0.000 description 5
230000008602 contraction Effects 0.000 description 5
230000000694 effects Effects 0.000 description 5
238000007912 intraperitoneal administration Methods 0.000 description 5
238000000034 method Methods 0.000 description 5
229940092253 ovalbumin Drugs 0.000 description 5
239000000243 solution Substances 0.000 description 5
-1 2-formyl-3-methyl-cyclopentyl Chemical group 0.000 description 4
241000700198 Cavia Species 0.000 description 4
PWWVAXIEGOYWEE-UHFFFAOYSA-N Isophenergan Chemical compound C1=CC=C2N(CC(C)N(C)C)C3=CC=CC=C3SC2=C1 PWWVAXIEGOYWEE-UHFFFAOYSA-N 0.000 description 4
241000700159 Rattus Species 0.000 description 4
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
230000002921 anti-spasmodic effect Effects 0.000 description 4
CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 description 4
239000003921 oil Substances 0.000 description 4
235000019198 oils Nutrition 0.000 description 4
229960003910 promethazine Drugs 0.000 description 4
206010002199 Anaphylactic shock Diseases 0.000 description 3
241000894006 Bacteria Species 0.000 description 3
206010013975 Dyspnoeas Diseases 0.000 description 3
241000588724 Escherichia coli Species 0.000 description 3
240000002218 Teucrium polium Species 0.000 description 3
235000019041 Teucrium polium Nutrition 0.000 description 3
208000003455 anaphylaxis Diseases 0.000 description 3
230000002804 anti-anaphylactic effect Effects 0.000 description 3
230000000844 anti-bacterial effect Effects 0.000 description 3
230000003385 bacteriostatic effect Effects 0.000 description 3
210000003405 ileum Anatomy 0.000 description 3
238000000338 in vitro Methods 0.000 description 3
238000002347 injection Methods 0.000 description 3
239000007924 injection Substances 0.000 description 3
238000002360 preparation method Methods 0.000 description 3
108010088751 Albumins Proteins 0.000 description 2
102000009027 Albumins Human genes 0.000 description 2
241000193830 Bacillus <bacterium> Species 0.000 description 2
241000700199 Cavia porcellus Species 0.000 description 2
208000000059 Dyspnea Diseases 0.000 description 2
241000196324 Embryophyta Species 0.000 description 2
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
241000588747 Klebsiella pneumoniae Species 0.000 description 2
241000588767 Proteus vulgaris Species 0.000 description 2
241000293869 Salmonella enterica subsp. enterica serovar Typhimurium Species 0.000 description 2
241000194017 Streptococcus Species 0.000 description 2
241001508780 Teucrium montanum Species 0.000 description 2
230000003110 anti-inflammatory effect Effects 0.000 description 2
208000008784 apnea Diseases 0.000 description 2
239000012736 aqueous medium Substances 0.000 description 2
244000052616 bacterial pathogen Species 0.000 description 2
230000015572 biosynthetic process Effects 0.000 description 2
239000002775 capsule Substances 0.000 description 2
239000002026 chloroform extract Substances 0.000 description 2
IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 2
229960000905 indomethacin Drugs 0.000 description 2
230000005764 inhibitory process Effects 0.000 description 2
229940007042 proteus vulgaris Drugs 0.000 description 2
229920006395 saturated elastomer Polymers 0.000 description 2
239000011780 sodium chloride Substances 0.000 description 2
239000002904 solvent Substances 0.000 description 2
238000003786 synthesis reaction Methods 0.000 description 2
DYLIWHYUXAJDOJ-OWOJBTEDSA-N (e)-4-(6-aminopurin-9-yl)but-2-en-1-ol Chemical compound NC1=NC=NC2=C1N=CN2C\C=C\CO DYLIWHYUXAJDOJ-OWOJBTEDSA-N 0.000 description 1
OIQOAYVCKAHSEJ-UHFFFAOYSA-N 2-[2,3-bis(2-hydroxyethoxy)propoxy]ethanol;hexadecanoic acid;octadecanoic acid Chemical compound OCCOCC(OCCO)COCCO.CCCCCCCCCCCCCCCC(O)=O.CCCCCCCCCCCCCCCCCC(O)=O OIQOAYVCKAHSEJ-UHFFFAOYSA-N 0.000 description 1
OFQCQIGMURIECL-UHFFFAOYSA-N 2-[2-(diethylamino)ethyl]-2',6'-dimethylspiro[isoquinoline-4,4'-oxane]-1,3-dione;phosphoric acid Chemical compound OP(O)(O)=O.O=C1N(CCN(CC)CC)C(=O)C2=CC=CC=C2C21CC(C)OC(C)C2 OFQCQIGMURIECL-UHFFFAOYSA-N 0.000 description 1
MZPIHWYCJUPOFB-UHFFFAOYSA-N 2-[2-(hydroxymethyl)-3-methylcyclopentyl]propan-1-ol Chemical compound OCC(C)C1CCC(C)C1CO MZPIHWYCJUPOFB-UHFFFAOYSA-N 0.000 description 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N EtOH Substances CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
241000699670 Mus sp. Species 0.000 description 1
239000007832 Na2SO4 Substances 0.000 description 1
241001274216 Naso Species 0.000 description 1
206010030113 Oedema Diseases 0.000 description 1
229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
241000588769 Proteus <enterobacteria> Species 0.000 description 1
PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
241001072888 Teucrium Species 0.000 description 1
OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 description 1
229960004266 acetylcholine chloride Drugs 0.000 description 1
239000002253 acid Substances 0.000 description 1
NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
239000002671 adjuvant Substances 0.000 description 1
238000006136 alcoholysis reaction Methods 0.000 description 1
229940121363 anti-inflammatory agent Drugs 0.000 description 1
239000002260 anti-inflammatory agent Substances 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
208000006673 asthma Diseases 0.000 description 1
WDIHJSXYQDMJHN-UHFFFAOYSA-L barium chloride Chemical compound [Cl-].[Cl-].[Ba+2] WDIHJSXYQDMJHN-UHFFFAOYSA-L 0.000 description 1
229910001626 barium chloride Inorganic materials 0.000 description 1
239000004044 bronchoconstricting agent Substances 0.000 description 1
230000003435 bronchoconstrictive effect Effects 0.000 description 1
229940124630 bronchodilator Drugs 0.000 description 1
235000010418 carrageenan Nutrition 0.000 description 1
229940113118 carrageenan Drugs 0.000 description 1
229920001525 carrageenan Polymers 0.000 description 1
239000000679 carrageenan Substances 0.000 description 1
238000009903 catalytic hydrogenation reaction Methods 0.000 description 1
239000000812 cholinergic antagonist Substances 0.000 description 1
230000007423 decrease Effects 0.000 description 1
238000004821 distillation Methods 0.000 description 1
BORBLDJNKYHVJP-UHFFFAOYSA-N dolichodial Chemical compound CC1CCC(C(=C)C=O)C1C=O BORBLDJNKYHVJP-UHFFFAOYSA-N 0.000 description 1
239000008298 dragée Substances 0.000 description 1
229940079593 drug Drugs 0.000 description 1
238000001035 drying Methods 0.000 description 1
238000002474 experimental method Methods 0.000 description 1
239000000284 extract Substances 0.000 description 1
238000000605 extraction Methods 0.000 description 1
239000012530 fluid Substances 0.000 description 1
239000011521 glass Substances 0.000 description 1
125000005456 glyceride group Chemical group 0.000 description 1
235000011187 glycerol Nutrition 0.000 description 1
239000002035 hexane extract Substances 0.000 description 1
238000005984 hydrogenation reaction Methods 0.000 description 1
238000001727 in vivo Methods 0.000 description 1
230000002401 inhibitory effect Effects 0.000 description 1
238000001990 intravenous administration Methods 0.000 description 1
238000010253 intravenous injection Methods 0.000 description 1
238000002386 leaching Methods 0.000 description 1
239000002609 medium Substances 0.000 description 1
239000002547 new drug Substances 0.000 description 1
230000003647 oxidation Effects 0.000 description 1
238000007254 oxidation reaction Methods 0.000 description 1
238000003359 percent control normalization Methods 0.000 description 1
208000023504 respiratory system disease Diseases 0.000 description 1
229910052938 sodium sulfate Inorganic materials 0.000 description 1
235000011152 sodium sulphate Nutrition 0.000 description 1
239000007901 soft capsule Substances 0.000 description 1
239000007787 solid Substances 0.000 description 1
239000012439 solid excipient Substances 0.000 description 1
241000894007 species Species 0.000 description 1
239000000126 substance Substances 0.000 description 1
230000004083 survival effect Effects 0.000 description 1
239000000725 suspension Substances 0.000 description 1
239000006188 syrup Substances 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
239000003826 tablet Substances 0.000 description 1
230000001988 toxicity Effects 0.000 description 1
231100000419 toxicity Toxicity 0.000 description 1
235000015112 vegetable and seed oil Nutrition 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
238000005303 weighing Methods 0.000 description 1
UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/05—Alcohols containing rings other than six-membered aromatic rings
- C07C33/12—Alcohols containing rings other than six-membered aromatic rings containing five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/14—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of a —CHO group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/17—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds
- C07C29/172—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds with the obtention of a fully saturated alcohol
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C31/27—Polyhydroxylic alcohols containing saturated rings
- C07C31/272—Monocyclic
- C07C31/274—Monocyclic with a three to five-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/28—Saturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings
- C07C47/30—Saturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings with a five-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/38—Unsaturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings
- C07C47/45—Unsaturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings having unsaturation outside the rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/06—Saturated compounds having a carboxyl group bound to a five-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/16—Unsaturated compounds
- C07C61/35—Unsaturated compounds having unsaturation outside the rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Oncology (AREA)
Pulmonology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Rheumatology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicinal Preparation (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

LU81352A 1978-06-03 1979-06-01 Medicament constitue par un derive de cyclopentyl-addehyde et composition le renfermant LU81352A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB7826316		1978-06-03
GB7826316		1978-06-03

Publications (1)

Publication Number	Publication Date
LU81352A1 true LU81352A1 (fr)	1980-01-22

Family

ID=10497850

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LU81352A LU81352A1 (fr)	1978-06-03	1979-06-01	Medicament constitue par un derive de cyclopentyl-addehyde et composition le renfermant

Country Status (16)

Country	Link
EP (1)	EP0006061B1 (it)
JP (1)	JPS5513269A (it)
AT (1)	ATE715T1 (it)
AU (1)	AU4760079A (it)
BE (1)	BE876713A (it)
CA (1)	CA1107761A (it)
CH (1)	CH639929A5 (it)
DE (1)	DE2962180D1 (it)
FR (1)	FR2427094B1 (it)
GB (1)	GB2022413B (it)
IE (1)	IE48343B1 (it)
IL (1)	IL57433A (it)
IT (1)	IT1120984B (it)
LU (1)	LU81352A1 (it)
NZ (1)	NZ190628A (it)
ZA (1)	ZA792678B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0505572A4 (en) *	1990-10-09	1993-03-10	Tsumura & Co.	Iridoide derivative and its use as medicine
CN102942605B (zh) *	2012-11-30	2016-06-15	沈阳药科大学	清香藤中环烯醚萜类化合物的制备方法及其应用
BR102017003318A2 (pt) *	2017-02-17	2018-10-30	Aché Laboratórios Farmacêuticos S.A.	compostos, processo de produção de compostos, extrato enriquecido, frações ativas de extrato enriquecido, processo de produção de extrato enriquecido, método de seleção de biomassa vegetal para produção de extrato enriquecido, composição e uso para tratamento de desordens imunológicas
IL296029A (en) *	2020-04-14	2022-10-01	Firmenich & Cie	Lily of the valley odorant

1979
- 1979-05-29 CH CH500979A patent/CH639929A5/fr not_active IP Right Cessation
- 1979-05-29 EP EP79400340A patent/EP0006061B1/fr not_active Expired
- 1979-05-29 DE DE7979400340T patent/DE2962180D1/de not_active Expired
- 1979-05-29 AT AT79400340T patent/ATE715T1/de not_active IP Right Cessation
- 1979-05-29 IL IL57433A patent/IL57433A/xx unknown
- 1979-05-30 ZA ZA792678A patent/ZA792678B/xx unknown
- 1979-05-30 CA CA328,873A patent/CA1107761A/en not_active Expired
- 1979-05-30 AU AU47600/79A patent/AU4760079A/en not_active Abandoned
- 1979-05-31 FR FR7914041A patent/FR2427094B1/fr not_active Expired
- 1979-06-01 NZ NZ190628A patent/NZ190628A/en unknown
- 1979-06-01 IT IT68189/79A patent/IT1120984B/it active
- 1979-06-01 BE BE2/57846A patent/BE876713A/xx not_active IP Right Cessation
- 1979-06-01 LU LU81352A patent/LU81352A1/fr unknown
- 1979-06-04 JP JP6980179A patent/JPS5513269A/ja active Pending
- 1979-06-04 GB GB7919435A patent/GB2022413B/en not_active Expired
- 1979-08-08 IE IE1087/79A patent/IE48343B1/en unknown

Also Published As

Publication number	Publication date
IE48343B1 (en)	1984-12-12
FR2427094A1 (fr)	1979-12-28
GB2022413B (en)	1983-02-16
CH639929A5 (fr)	1983-12-15
IE791087L (en)	1979-12-03
IL57433A0 (en)	1979-09-30
JPS5513269A (en)	1980-01-30
DE2962180D1 (en)	1982-03-25
CA1107761A (en)	1981-08-25
EP0006061B1 (fr)	1982-02-24
BE876713A (fr)	1979-12-03
NZ190628A (en)	1984-11-09
AU4760079A (en)	1979-12-13
IT1120984B (it)	1986-03-26
IT7968189A0 (it)	1979-06-01
FR2427094B1 (fr)	1986-07-25
ZA792678B (en)	1980-08-27
IL57433A (en)	1982-08-31
GB2022413A (en)	1979-12-19
EP0006061A1 (fr)	1979-12-12
ATE715T1 (de)	1982-03-15

Publication	Publication Date	Title
US4988733A (en)	1991-01-29	N-[1-(3-phenoxyphenyl)ethyl]acetohydroxamic acid compounds which are useful anti-inflammatory agents
FR2491060A1 (fr)	1982-04-02	Esters d'acides cyclopropanes carboxyliques apparentes a l'acide pyrethrique, leur procede de preparation et leur application a la lutte contre les parasites
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EP1014927B1 (fr)	2003-06-25	Utilisation des shogaols et des gingerols pour la preparation de compositions deodorantes
EP0006061B1 (fr)	1982-02-24	Médicament constitué par un dérivé de cyclopentyl-aldéhyde
FR2481271A1 (fr)	1981-10-30	Derives de la nonaprenylamine, leurs sels acides d'addition et leur utilisation dans des compositions pharmaceutiques
CH621325A5 (it)	1981-01-30
FR2559771A1 (fr)	1985-08-23	Derives de la 3-pyrrolidinopropiophenone et procede pour leur preparation
US20050203180A1 (en)	2005-09-15	Cinnamic acid dimers, their preparation and the use thereof for treating neurodegenerative disease
EP0135510B1 (fr)	1986-08-20	Nouveaux medicaments appartenant a la famille des derives d'halo genobenzophenone-oxime
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