LU92114I2 - Ferumoxytol - Google Patents
FerumoxytolInfo
- Publication number
- LU92114I2 LU92114I2 LU92114C LU92114C LU92114I2 LU 92114 I2 LU92114 I2 LU 92114I2 LU 92114 C LU92114 C LU 92114C LU 92114 C LU92114 C LU 92114C LU 92114 I2 LU92114 I2 LU 92114I2
- Authority
- LU
- Luxembourg
- Prior art keywords
- compositions
- methods
- agent
- ferumoxytol
- agents
- Prior art date
Links
- 229940102709 ferumoxytol Drugs 0.000 title 1
- UCNNJGDEJXIUCC-UHFFFAOYSA-L hydroxy(oxo)iron;iron Chemical compound [Fe].O[Fe]=O.O[Fe]=O UCNNJGDEJXIUCC-UHFFFAOYSA-L 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 229920002307 Dextran Polymers 0.000 abstract 1
- 239000004606 Fillers/Extenders Substances 0.000 abstract 1
- 239000003173 antianemic agent Substances 0.000 abstract 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 239000012216 imaging agent Substances 0.000 abstract 1
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N iron oxide Inorganic materials [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 abstract 1
- 235000013980 iron oxide Nutrition 0.000 abstract 1
- VBMVTYDPPZVILR-UHFFFAOYSA-N iron(2+);oxygen(2-) Chemical class [O-2].[Fe+2] VBMVTYDPPZVILR-UHFFFAOYSA-N 0.000 abstract 1
- 238000002595 magnetic resonance imaging Methods 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6923—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
- A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
- A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
- A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
- A61K49/1851—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule
- A61K49/1863—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule the organic macromolecular compound being a polysaccharide or derivative thereof, e.g. chitosan, chitin, cellulose, pectin, starch
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nanotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Ceramic Engineering (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Hematology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Diabetes (AREA)
- Radiology & Medical Imaging (AREA)
- Toxicology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Compounds Of Iron (AREA)
- Cookers (AREA)
- Chemical Treatment Of Metals (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Materials Applied To Surfaces To Minimize Adherence Of Mist Or Water (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12857999P | 1999-04-09 | 1999-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LU92114I2 true LU92114I2 (fr) | 2013-12-14 |
Family
ID=22436002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LU92114C LU92114I2 (fr) | 1999-04-09 | 2012-12-14 | Ferumoxytol |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6599498B1 (fr) |
| EP (1) | EP1169062B1 (fr) |
| JP (2) | JP5064612B2 (fr) |
| AT (1) | ATE446108T1 (fr) |
| CY (1) | CY1109527T1 (fr) |
| DE (1) | DE60043188D1 (fr) |
| DK (1) | DK1169062T3 (fr) |
| ES (1) | ES2334555T3 (fr) |
| LU (1) | LU92114I2 (fr) |
| PT (1) | PT1169062E (fr) |
| WO (1) | WO2000061191A2 (fr) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7871597B2 (en) | 1999-04-09 | 2011-01-18 | Amag Pharmaceuticals, Inc. | Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents |
| US7169618B2 (en) * | 2000-06-28 | 2007-01-30 | Skold Technology | Magnetic particles and methods of producing coated magnetic particles |
| US6690962B2 (en) | 2000-09-15 | 2004-02-10 | Institut fur Diagnostikforshung GmbH | Process for graphic visualization and diagnosis of thrombi by means of nuclear spin tomography with use of particulate contrast media |
| DE10046514A1 (de) * | 2000-09-15 | 2002-04-25 | Diagnostikforschung Inst | Verfahren zur bildlichen Darstellung und Diagnose von Thromben mittels Kernspintomographie unter Verwendung partikulärer Kontrastmittel |
| AU2002220280A1 (en) * | 2000-12-07 | 2002-06-18 | Ad "Zdravlje" Farmaceutsko - Hemijska Industrija, Centar Za Istrazivanje I Razvoj | Polynuclear complex fe(iii) with pullulan oligomers, process of its obtaining, and pharmaceutical preparations on the basis of the complex |
| CN1522161A (zh) | 2001-06-29 | 2004-08-18 | �Ȱ�ά����ķ�ɷݹ�˾ | 批量高压灭菌方法 |
| US20030124194A1 (en) | 2002-01-02 | 2003-07-03 | Gaw Debra A. | Amine functionalized superparamagnetic nanoparticles for the synthesis of bioconjugates and uses therefor |
| DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| US20060018835A1 (en) * | 2004-04-02 | 2006-01-26 | General Electric Company | Nanoparticles with inorganic core and methods of using them |
| US20060014938A1 (en) * | 2004-07-14 | 2006-01-19 | Groman Ernest V | Stable aqueous colloidal lanthanide oxides |
| US20060140867A1 (en) * | 2004-12-28 | 2006-06-29 | Helfer Jeffrey L | Coated stent assembly and coating materials |
| CA2606924C (fr) | 2005-05-09 | 2013-04-16 | The General Hospital Corporation | Capteurs a relaxation par eau |
| CA2620861C (fr) | 2005-08-31 | 2016-07-05 | T2 Biosystems, Inc. | Dispositif rmn pour la detection d'analytes |
| US20070077313A1 (en) * | 2005-10-04 | 2007-04-05 | U.S. Pharmaceutical Corporation | Toleration iron supplement compositions |
| WO2007136413A2 (fr) | 2005-12-22 | 2007-11-29 | Visen Medical, Inc. | Nanoparticules d'oxyde métallique fluorescentes biocompatibles |
| PT1973549T (pt) * | 2006-01-06 | 2016-10-25 | Luitpold Pharm Inc | Métodos e composições para administração de ferro |
| AU2016205002C1 (en) * | 2006-01-06 | 2020-09-24 | Vifor (International) Ag | Methods and compositions for administration of iron |
| AU2013206429B2 (en) * | 2006-01-06 | 2016-04-28 | Vifor (International) Ag | Methods and compositions for administration of iron |
| NO329127B1 (no) * | 2006-09-12 | 2010-08-30 | Epitarget As | Sporbart partikulaert materiale for legemiddelavlevering omfattende et matriseeller membranmateriale, et legemiddel, og et T1- og et T2*- magnetisk resonanskontrastmiddel |
| EP2084550A1 (fr) * | 2006-11-08 | 2009-08-05 | T2 Biosystems, Inc. | Systemes rmn de detection d'analytes in vivo |
| EP2131870B1 (fr) * | 2007-04-12 | 2016-03-16 | Industry-Academic Cooperation Foundation, Yonsei University | Agent de contraste d'IRM comportant des nanoparticules d'oxyde métallique contenants du zinc |
| US20120003160A1 (en) * | 2007-06-29 | 2012-01-05 | Amag Pharmaceuticals, Inc. | Macrophage-Enhanced MRI (MEMRI) in a Single Imaging Session |
| WO2009045354A1 (fr) | 2007-09-28 | 2009-04-09 | T2 Biosystems, Inc. | Diagnostic par rmn utilisant un récipient d'échantillons en plastiques |
| AU2008325088A1 (en) | 2007-11-06 | 2009-05-14 | T2 Biosystems, Inc. | Small magnet and RF coil for magnetic resonance relaxometry |
| JP2011503232A (ja) | 2007-11-20 | 2011-01-27 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | 免疫応答の調節 |
| EP2277181B1 (fr) * | 2008-04-16 | 2017-08-30 | StemCell Technologies Inc. | Particules magnétiques |
| JP5926958B2 (ja) | 2008-10-29 | 2016-05-25 | ティー2 バイオシステムズ,インコーポレーテッド | 凝固時間のnmr検出 |
| US8840868B2 (en) | 2009-02-04 | 2014-09-23 | The Regents Of The University Of Colorado, A Body Corporate | Non-invasive detection of complement-mediated inflammation using CR2-targeted nanoparticles |
| JP5841044B2 (ja) | 2009-03-23 | 2016-01-06 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドThe Brigham and Women’s Hospital, Inc. | 複合糖質ワクチン |
| CN109700828A (zh) | 2009-03-25 | 2019-05-03 | 法码科思莫斯控股有限公司 | 稳定的铁寡糖复合物 |
| WO2011005496A2 (fr) | 2009-06-22 | 2011-01-13 | Massachusetts Eye & Ear Infirmary | Islet1 (isl1) et perte d'audition |
| WO2011150212A2 (fr) | 2010-05-26 | 2011-12-01 | The General Hospital Corporation | Nanoparticules magnétiques |
| US9636423B2 (en) | 2010-06-02 | 2017-05-02 | The General Hospital Corporation | Optical sensor conjugates for detecting reactive oxygen and/or reactive nitrogen species in vivo |
| CN102451185A (zh) | 2010-10-19 | 2012-05-16 | 长春纳米生技公司 | 金属离子纳米簇组合物 |
| US8409807B2 (en) | 2010-10-22 | 2013-04-02 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| US8563298B2 (en) | 2010-10-22 | 2013-10-22 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| WO2012054639A2 (fr) | 2010-10-22 | 2012-04-26 | T2 Biosystems, Inc. | Systèmes de rmn et procédés de détection rapide d'analytes |
| CN102086232B (zh) * | 2010-12-15 | 2012-05-23 | 吕辉 | 一种多糖铁的制备方法 |
| EP2732046B1 (fr) | 2011-07-13 | 2017-09-06 | T2 Biosystems, Inc. | Procédés de résonance magnétique nucléaire (rmn )pour surveiller la formation de caillots sanguins |
| DK2741765T3 (en) | 2011-08-10 | 2016-06-13 | Adocia | Injectable solution of at least one type of basal insulin |
| US10620205B2 (en) | 2011-09-21 | 2020-04-14 | T2 Biosystems, Inc. | NMR methods for endotoxin analysis |
| US9958416B2 (en) | 2011-11-23 | 2018-05-01 | The General Hospital Corporation | Analyte detection using magnetic hall effect |
| CN107583039A (zh) | 2012-01-09 | 2018-01-16 | 阿道恰公司 | Ph为7且至少含pi为5.8至8.5之基础胰岛素和取代共聚(氨基酸)的可注射溶液 |
| EP2647389A1 (fr) | 2012-04-04 | 2013-10-09 | Charité - Universitätsmedizin Berlin | Dispersion de nanoparticules magnétiques, sa préparation et diagnostic et utilisation thérapeutique |
| WO2013158281A1 (fr) | 2012-04-20 | 2013-10-24 | T2 Biosystems, Inc. | Compositions et procédés de détection d'espèces de candida |
| US10274490B2 (en) | 2012-06-12 | 2019-04-30 | The General Hospital Corporation | Magnetic labeling of bacteria |
| WO2014004577A1 (fr) | 2012-06-25 | 2014-01-03 | The General Hospital Corporation | Tri de particules au moyen de champs magnétiques à gradient élevé |
| US9675640B2 (en) * | 2012-08-07 | 2017-06-13 | Southwest Research Institute | Magnetic calcium phosphate nanoparticles, applications and methods of preparation thereof |
| US20150314003A2 (en) | 2012-08-09 | 2015-11-05 | Adocia | Injectable solution at ph 7 comprising at least one basal insulin the isoelectric point of which is between 5.8 and 8.5 and a hydrophobized anionic polymer |
| US9739733B2 (en) | 2012-12-07 | 2017-08-22 | T2 Biosystems, Inc. | Methods for monitoring tight clot formation |
| US9370202B2 (en) | 2013-03-15 | 2016-06-21 | LG Bionano, LLC | Encapsulated metal ion nanoclusters |
| KR102218494B1 (ko) | 2013-03-15 | 2021-02-19 | 인트린식 라이프사이언시스, 엘엘씨 | 항-헵시딘 항체 및 그의 용도 |
| US10202577B2 (en) | 2013-10-18 | 2019-02-12 | The General Hospital Corporation | Microfluidic sorting using high gradient magnetic fields |
| US9566216B2 (en) | 2013-11-18 | 2017-02-14 | Southwest Research Institute | Bone cements containing magnetic calcium phosphate nanoparticles |
| KR20150078375A (ko) | 2013-12-30 | 2015-07-08 | 한화케미칼 주식회사 | 철산화물 나노입자를 포함하는 철결핍증의 예방 또는 치료용 약학 조성물 |
| US10898581B2 (en) | 2014-01-16 | 2021-01-26 | The Brigham And Women's Hospital, Inc. | Targeted delivery of immunoregulatory drugs |
| TWI689310B (zh) | 2014-07-11 | 2020-04-01 | 巨生生醫股份有限公司 | 治療鐵缺乏症之方法 |
| AU2015321462B2 (en) | 2014-09-22 | 2020-04-30 | Intrinsic Lifesciences Llc | Humanized anti-hepcidin antibodies and uses thereof |
| CA2966623C (fr) | 2014-11-03 | 2024-02-20 | The General Hospital Corporation | Concentration de particules dans un dispositif microfluidique |
| CN105597105B (zh) * | 2014-11-19 | 2020-03-10 | 连云港润众制药有限公司 | 一种菲立莫妥的制备方法 |
| EP3274053A4 (fr) | 2015-03-23 | 2018-12-05 | The Brigham and Women's Hospital, Inc. | Nanoparticules tolérogéniques pour le traitement du diabète sucré |
| US10258647B2 (en) | 2015-09-01 | 2019-04-16 | Particle Dynamics International, Llc | Iron-polysaccharide complexes and methods for the preparation thereof |
| US11519016B2 (en) | 2016-01-21 | 2022-12-06 | T2 Biosystems, Inc. | NMR methods and systems for the rapid detection of bacteria |
| CN105708792A (zh) * | 2016-01-28 | 2016-06-29 | 山西普德药业股份有限公司 | 一种还原型羧烷基葡聚糖铁注射液及其制备方法 |
| CN105616372A (zh) * | 2016-01-28 | 2016-06-01 | 山西普德药业股份有限公司 | 一种还原型羧烷基葡聚糖铁片剂 |
| CN105708805A (zh) * | 2016-01-28 | 2016-06-29 | 山西普德药业股份有限公司 | 一种还原型羧烷基葡聚糖铁及其制备方法 |
| TR201703251A2 (tr) | 2017-03-03 | 2017-07-21 | Berna Buelbuel | Kansizliğin transdermal yoldan tedavi̇si̇nde kullanilacak demi̇r oksi̇t nanokri̇stalleri̇ i̇çeren solüsyon |
| CN108403716B (zh) * | 2018-06-25 | 2021-11-05 | 博瑞生物医药(苏州)股份有限公司 | 一种超顺磁氧化铁的制备方法 |
| KR20210126078A (ko) | 2019-02-13 | 2021-10-19 | 더 브리검 앤드 우먼즈 하스피털, 인크. | 항-말초 림프절 어드레신 항체 및 그의 용도 |
| WO2025043086A1 (fr) | 2023-08-22 | 2025-02-27 | Navinta, Llc | Procédé amélioré pour la préparation de férumoxytol solide |
| WO2026017901A1 (fr) | 2024-07-18 | 2026-01-22 | Malian Biologicals Gmbh | Supplémentation en fer dans un trouble du neurodéveloppement ou psychiatrique |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2885393A (en) | 1956-02-24 | 1959-05-05 | R K Laros Company | Dextran-iron complex and process for making same |
| US2862920A (en) | 1956-06-07 | 1958-12-02 | Ohio Commw Eng Co | Ferrous carboxymethyl dextran |
| US3000872A (en) | 1956-06-15 | 1961-09-19 | Ohio Commw Eng Co | Preparation of carboxymethyl dextran-iron complexes |
| US2856398A (en) | 1956-06-15 | 1958-10-14 | Ohio Commw Eng Co | Carboxymethyl dextran-iron complexes |
| US2856366A (en) | 1956-07-30 | 1958-10-14 | Ohio Commw Eng Co | Stable alkaline metal solutions containing carboxymethyl dextran |
| US3151107A (en) | 1960-12-22 | 1964-09-29 | Central Pharmacal Company | Water-soluble iron complexes of carboxymethyl dextran |
| GB1019513A (en) * | 1961-08-07 | 1966-02-09 | Chemicals Inc | Iron dextran complexes |
| US3234209A (en) * | 1963-09-13 | 1966-02-08 | Chemicals Inc | Process for making iron hydrogenated dextran |
| JPS5913521B2 (ja) | 1975-06-19 | 1984-03-30 | メイトウサンギヨウ カブシキガイシヤ | 磁性酸化鉄・デキストラン複合体の製造法 |
| US4180567A (en) | 1977-09-02 | 1979-12-25 | Pharmachem Corporation | Iron preparations and methods of making and administering the same |
| US4452773A (en) * | 1982-04-05 | 1984-06-05 | Canadian Patents And Development Limited | Magnetic iron-dextran microspheres |
| EP0230768B1 (fr) | 1985-12-20 | 1992-03-18 | Syntex (U.S.A.) Inc. | Procédé de séparation de particules |
| US5076950A (en) | 1985-12-20 | 1991-12-31 | Syntex (U.S.A.) Inc. | Magnetic composition for particle separation |
| US4827945A (en) | 1986-07-03 | 1989-05-09 | Advanced Magnetics, Incorporated | Biologically degradable superparamagnetic materials for use in clinical applications |
| US5055288A (en) | 1987-06-26 | 1991-10-08 | Advanced Magnetics, Inc. | Vascular magnetic imaging method and agent comprising biodegradeable superparamagnetic metal oxides |
| US4770183A (en) | 1986-07-03 | 1988-09-13 | Advanced Magnetics Incorporated | Biologically degradable superparamagnetic particles for use as nuclear magnetic resonance imaging agents |
| US5102652A (en) | 1986-07-03 | 1992-04-07 | Advanced Magnetics Inc. | Low molecular weight carbohydrates as additives to stabilize metal oxide compositions |
| US5262176A (en) | 1986-07-03 | 1993-11-16 | Advanced Magnetics, Inc. | Synthesis of polysaccharide covered superparamagnetic oxide colloids |
| US5160726A (en) | 1990-02-15 | 1992-11-03 | Advanced Magnetics Inc. | Filter sterilization for production of colloidal, superparamagnetic MR contrast agents |
| GB8808305D0 (en) * | 1988-04-08 | 1988-05-11 | Nycomed As | Compositions |
| JP2726520B2 (ja) | 1989-10-20 | 1998-03-11 | 名糖産業株式会社 | 有機磁性複合体 |
| JPH05502944A (ja) * | 1989-12-22 | 1993-05-20 | モレキュラ バイオクエスト インコーポレイテッド | 分離に使用するための有機金属で被覆された粒子 |
| GB9416767D0 (en) * | 1994-08-18 | 1994-10-12 | Nycomed Innovation Ab | Compositions |
| DE69421943T2 (de) * | 1994-09-27 | 2000-05-18 | Nycomed Imaging As, Oslo | Kontrastmittel |
| JP4070150B2 (ja) | 1996-08-30 | 2008-04-02 | 名糖産業株式会社 | 多糖誘導体―磁性金属酸化物複合体 |
| DK172860B1 (da) * | 1998-03-25 | 1999-08-16 | Pharmacosmos Holding As | Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman |
| DK173138B1 (da) | 1998-11-20 | 2000-02-07 | Pharmacosmos Holding As | Fremgangsmåde til fremstilling af en jerndextranforbindelse, jerndextranforbindelse fremstillet efter fremgangsmåden, farma |
-
2000
- 2000-03-08 PT PT00914867T patent/PT1169062E/pt unknown
- 2000-03-08 EP EP00914867A patent/EP1169062B1/fr not_active Revoked
- 2000-03-08 US US09/521,264 patent/US6599498B1/en not_active Expired - Lifetime
- 2000-03-08 DK DK00914867.7T patent/DK1169062T3/da active
- 2000-03-08 WO PCT/US2000/006047 patent/WO2000061191A2/fr not_active Ceased
- 2000-03-08 ES ES00914867T patent/ES2334555T3/es not_active Expired - Lifetime
- 2000-03-08 DE DE60043188T patent/DE60043188D1/de not_active Expired - Lifetime
- 2000-03-08 JP JP2000610523A patent/JP5064612B2/ja not_active Expired - Fee Related
- 2000-03-08 AT AT00914867T patent/ATE446108T1/de active
-
2003
- 2003-03-11 US US10/386,394 patent/US7553479B2/en not_active Expired - Fee Related
-
2009
- 2009-12-01 CY CY20091101262T patent/CY1109527T1/el unknown
-
2010
- 2010-12-09 JP JP2010275172A patent/JP2011046752A/ja not_active Withdrawn
-
2012
- 2012-12-14 LU LU92114C patent/LU92114I2/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000061191A9 (fr) | 2001-06-21 |
| US7553479B2 (en) | 2009-06-30 |
| US20030225033A1 (en) | 2003-12-04 |
| WO2000061191A2 (fr) | 2000-10-19 |
| DK1169062T3 (da) | 2010-01-25 |
| PT1169062E (pt) | 2009-12-17 |
| JP2011046752A (ja) | 2011-03-10 |
| ATE446108T1 (de) | 2009-11-15 |
| US6599498B1 (en) | 2003-07-29 |
| EP1169062A2 (fr) | 2002-01-09 |
| JP2002541218A (ja) | 2002-12-03 |
| CY1109527T1 (el) | 2014-08-13 |
| ES2334555T3 (es) | 2010-03-12 |
| WO2000061191A3 (fr) | 2001-05-25 |
| DE60043188D1 (de) | 2009-12-03 |
| JP5064612B2 (ja) | 2012-10-31 |
| EP1169062B1 (fr) | 2009-10-21 |
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