LV11993B - Peptīdi un to iegūšanas paņēmiens - Google Patents

Peptīdi un to iegūšanas paņēmiens Download PDF

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Publication number
LV11993B
LV11993B LVP-97-186A LV970186A LV11993B LV 11993 B LV11993 B LV 11993B LV 970186 A LV970186 A LV 970186A LV 11993 B LV11993 B LV 11993B
Authority
LV
Latvia
Prior art keywords
trp
nval
tyr
ala
pro
Prior art date
Application number
LVP-97-186A
Other languages
English (en)
Latvian (lv)
Other versions
LV11993A (lv
Inventor
Vladislav Deigin
Andrei Korotkov
Original Assignee
Vladislav Deigin
Andrei Korotkov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vladislav Deigin, Andrei Korotkov filed Critical Vladislav Deigin
Publication of LV11993A publication Critical patent/LV11993A/xx
Publication of LV11993B publication Critical patent/LV11993B/lv

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/021Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0815Tripeptides with the first amino acid being basic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0819Tripeptides with the first amino acid being acidic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0823Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1021Tetrapeptides with the first amino acid being acidic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1024Tetrapeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LVP-97-186A 1995-03-02 1997-10-02 Peptīdi un to iegūšanas paņēmiens LV11993B (lv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU95102461A RU2107691C1 (ru) 1995-03-02 1995-03-02 Пептид и способ его получения
PCT/RU1996/000046 WO1996026955A1 (en) 1995-03-02 1996-02-28 Peptide and a method of obtaining it

Publications (2)

Publication Number Publication Date
LV11993A LV11993A (lv) 1998-03-20
LV11993B true LV11993B (lv) 1998-05-20

Family

ID=20164981

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-97-186A LV11993B (lv) 1995-03-02 1997-10-02 Peptīdi un to iegūšanas paņēmiens

Country Status (19)

Country Link
US (1) US6051683A (de)
EP (1) EP0818462B1 (de)
JP (1) JP3902226B2 (de)
CN (1) CN1161373C (de)
AT (1) ATE306495T1 (de)
AU (1) AU708084B2 (de)
BR (1) BR9607901A (de)
CA (1) CA2214410C (de)
CZ (1) CZ288418B6 (de)
DE (1) DE69635272T2 (de)
DK (1) DK0818462T3 (de)
ES (1) ES2250984T3 (de)
HU (1) HUP0000320A3 (de)
LT (1) LT4393B (de)
LV (1) LV11993B (de)
RU (1) RU2107691C1 (de)
SK (1) SK282604B6 (de)
UA (1) UA51647C2 (de)
WO (1) WO1996026955A1 (de)

Families Citing this family (19)

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US6159940A (en) * 1996-02-28 2000-12-12 Immunotech Developments Inc. Method for modulating hemopoiesis
DE19712633A1 (de) * 1997-03-26 1998-10-08 Laves Arzneimittel Verwendung von gamma-Aminobuttersäure als Interleukinbildungsstimulans
IL137820A (en) * 2000-08-10 2009-06-15 S I S Shulov Inst For Science Pharmaceutical composition for topical administration comprising an analgesic peptide
AU2002211863A1 (en) * 2000-10-06 2002-04-15 Xenoport, Inc. Bile-acid derived compounds for providing sustained systemic concentrations of drugs after oral administration
US20020098999A1 (en) * 2000-10-06 2002-07-25 Gallop Mark A. Compounds for sustained release of orally delivered drugs
RU2177803C1 (ru) * 2000-10-30 2002-01-10 Цепелев Виктор Львович Средство, обладающее иммуностимулирующей активностью
WO2002042414A2 (en) * 2000-11-17 2002-05-30 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
AU2002345638A1 (en) * 2001-06-11 2002-12-23 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
BRPI0402260B1 (pt) 2004-06-15 2015-02-18 Botica Com Farmaceutica Ltda Composição para produtos de higiene, cosméticos e perfumes.
US7919468B2 (en) 2005-04-07 2011-04-05 Centre National De La Recherche Scientifique (C.N.R.S.) Compounds useful as modulators of the proteasome activity
CA2571645A1 (en) 2006-12-19 2008-06-19 Apotex Technologies Inc. Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture
US20110003751A1 (en) * 2007-11-20 2011-01-06 Deigin Vladislav I Novel Immunoregulatory Peptides, Compositions and Uses Thereof
RU2410391C1 (ru) * 2009-06-03 2011-01-27 Общество с ограниченной ответственностью "Пептос Фарма" Пептиды, влияющие на регенерацию кроветворной системы, и фармацевтическая композиция на их основе
CN102724998A (zh) 2009-08-10 2012-10-10 伊姆诺科技发展公司 用于引发特异性免疫应答以治疗病毒感染和其他病症的具有肽佐剂的疫苗
RU2458935C1 (ru) * 2011-02-18 2012-08-20 Общество с ограниченной ответственностью "ЦитоНИР" (ООО "ЦитоНИР") Средство для коррекции метаболического синдрома
EP2818477B1 (de) * 2012-05-18 2016-05-04 Obshestvo S Organichennoj Otvetstvennostju "CytoNIR" L-lysyl-l-glutamyl-l-tryptophan zur korrektur des stoffwechselsyndroms
RU2540496C1 (ru) * 2014-01-20 2015-02-10 Общество с ограниченной ответственностью "ПРОМОМЕД" Композиция для назального применения, лекарственное средство на его основе и способ его пременения
EA025690B1 (ru) * 2014-07-15 2017-01-30 Государственное бюджетное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет" Министерства здравоохранения Российской Федерации Ранозаживляющее средство, обладающее иммуностимулирующим и антиоксидантным эффектами
RU2672888C1 (ru) 2018-04-18 2018-11-20 Пивипи Лабс Пте. Лтд. Противовирусное иммунотропное средство для лечения ОРВИ

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DE3100974A1 (de) * 1980-01-18 1982-01-21 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-fragmente enthaltende arzneimittel mit immunregulierender wirkung, und thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-fragmente
HU185263B (en) * 1981-06-12 1984-12-28 Richter Gedeon Vegyeszet Process for producing peptides effective on the immuncontroll analogous with the tp5
JPS609182Y2 (ja) * 1981-06-18 1985-04-02 アルファレコ−ド株式会社 カセツトテ−プケ−スマガジン
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US5021551A (en) * 1989-01-18 1991-06-04 Washington University Method of enhancing peptide immunogenicity
SU1737798A1 (ru) * 1989-04-11 1995-03-20 Институт клинической иммунологии СО АМН СССР Способ получения иммуностимулирующих тимусных полипептидов
GB2231051B (en) * 1989-05-05 1992-12-16 Erba Carlo Spa Bombesin antagonists
IT1230733B (it) * 1989-06-30 1991-10-29 Eniricerche Spa Analoghi della timopentina retro invertita a tutti i legami, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche.
EP0563212A1 (de) * 1990-11-23 1993-10-06 Immunodynamics, Inc. Synthetische immunoaktive peptide mit immunmodulierenden und therapeutischen wirkungen
ATE188219T1 (de) * 1991-10-28 2000-01-15 Cytran Ltd Pharmazeutische dipeptid zusammensetzungen und verwendungsmethoden.
IT1264129B1 (it) * 1993-04-09 1996-09-16 Codev S A Peptidi ad attivita' immunomodulatoria derivati da frammenti di leucochinina
AU7392294A (en) * 1993-07-21 1995-02-20 Vladimir Khatskelevich Khavinson Pharmaceutical with immunomodulating activity
RU2067000C1 (ru) * 1994-06-29 1996-09-27 Владислав Исакович Дейгин Пептид и способ его получения
RU2107692C1 (ru) * 1995-06-07 1998-03-27 Дейгин Владислав Исакович Пептид и способ его получения

Also Published As

Publication number Publication date
CN1161373C (zh) 2004-08-11
UA51647C2 (uk) 2002-12-16
LT97158A (en) 1998-05-25
EP0818462A1 (de) 1998-01-14
ES2250984T3 (es) 2006-04-16
HUP0000320A2 (hu) 2000-08-28
US6051683A (en) 2000-04-18
SK282604B6 (sk) 2002-10-08
CA2214410C (en) 2001-05-29
CZ288418B6 (en) 2001-06-13
DK0818462T3 (da) 2006-02-27
AU708084B2 (en) 1999-07-29
LV11993A (lv) 1998-03-20
SK118097A3 (en) 1998-04-08
AU4959496A (en) 1996-09-18
EP0818462B1 (de) 2005-10-12
CZ270397A3 (cs) 1998-05-13
HUP0000320A3 (en) 2000-10-30
BR9607901A (pt) 1999-09-08
JP3902226B2 (ja) 2007-04-04
EP0818462A4 (de) 2000-05-31
CA2214410A1 (en) 1996-09-06
DE69635272D1 (de) 2006-02-23
RU2107691C1 (ru) 1998-03-27
DE69635272T2 (de) 2006-07-20
RU95102461A (ru) 1996-12-20
CN1185160A (zh) 1998-06-17
ATE306495T1 (de) 2005-10-15
JPH11505515A (ja) 1999-05-21
LT4393B (lt) 1998-10-26
WO1996026955A1 (en) 1996-09-06
HK1012859A1 (en) 1999-08-13

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