LV12941B - Mesoprogestins (progesterone receptor modulators) for the treatment and prevention of benign hormone dependent gynecological disorders - Google Patents

Mesoprogestins (progesterone receptor modulators) for the treatment and prevention of benign hormone dependent gynecological disorders Download PDF

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Publication number
LV12941B
LV12941B LVP-02-53A LV020053A LV12941B LV 12941 B LV12941 B LV 12941B LV 020053 A LV020053 A LV 020053A LV 12941 B LV12941 B LV 12941B
Authority
LV
Latvia
Prior art keywords
treatment
endometriosis
dysmenorrhea
mesoprogestin
prevention
Prior art date
Application number
LVP-02-53A
Other languages
English (en)
Latvian (lv)
Inventor
Kristof Chwalisz
Walter Elger
Gerd Schubert
Original Assignee
Schering Ag
Jenapharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag, Jenapharm Gmbh filed Critical Schering Ag
Publication of LV12941B publication Critical patent/LV12941B/lv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Pyridine Compounds (AREA)
LVP-02-53A 1999-08-31 2002-03-28 Mesoprogestins (progesterone receptor modulators) for the treatment and prevention of benign hormone dependent gynecological disorders LV12941B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38614199A 1999-08-31 1999-08-31

Publications (1)

Publication Number Publication Date
LV12941B true LV12941B (en) 2003-06-20

Family

ID=23524338

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-02-53A LV12941B (en) 1999-08-31 2002-03-28 Mesoprogestins (progesterone receptor modulators) for the treatment and prevention of benign hormone dependent gynecological disorders

Country Status (34)

Country Link
EP (1) EP1229906B1 (fr)
JP (1) JP2003535029A (fr)
KR (3) KR20080066095A (fr)
AR (1) AR025457A1 (fr)
AT (1) ATE375160T1 (fr)
AU (1) AU781840B2 (fr)
BG (1) BG65817B1 (fr)
BR (1) BR0014161A (fr)
CA (1) CA2382580C (fr)
CO (1) CO5200772A1 (fr)
CZ (1) CZ2002704A3 (fr)
DE (1) DE60036723T2 (fr)
DK (1) DK1229906T3 (fr)
EA (1) EA007854B1 (fr)
EE (1) EE05172B1 (fr)
ES (1) ES2295050T3 (fr)
HR (1) HRP20020267A2 (fr)
HU (1) HUP0202429A3 (fr)
IL (1) IL148416A0 (fr)
LT (1) LT5034B (fr)
LV (1) LV12941B (fr)
ME (1) MEP13808A (fr)
MX (1) MXPA02002191A (fr)
NO (1) NO20020999L (fr)
NZ (1) NZ517471A (fr)
PE (1) PE20010578A1 (fr)
PL (1) PL198790B1 (fr)
PT (1) PT1229906E (fr)
RO (1) RO122179B1 (fr)
RS (1) RS50283B (fr)
SI (1) SI20852B (fr)
SK (1) SK287192B6 (fr)
UA (1) UA78184C2 (fr)
WO (1) WO2001015679A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004014935A1 (fr) * 2002-08-02 2004-02-19 Schering Aktiengesellschaft Modulateurs de recepteurs de progesterone presentant une activite antigonadotrope augmentee, destines au controle de fertilite et au traitement hormonal substitutif chez la femme
DE10236405A1 (de) 2002-08-02 2004-02-19 Schering Ag Progesteronrezeptormodulatoren mit erhöhter antigonadotroper Aktivität für die weibliche Fertilitätskontrolle und Hormonersatztherapie
US20040097591A1 (en) * 2002-11-18 2004-05-20 Kristof Chwalisz Use of selective progesterone receptor modulators for the treatment of androgen deficiency
RU2301691C1 (ru) * 2005-12-20 2007-06-27 Государственное учреждение Научный центр акушерства, гинекологии и перинатологии Российской академии медицинских наук Способ восстановительного лечения женщин репродуктивного возраста с тазовыми перитонеальными спайками с фиксированной или субфиксированной ретродевиацией матки
DE102007011105A1 (de) 2007-03-02 2008-09-04 Bayer Schering Pharma Aktiengesellschaft Mineralcorticoid-Rezeptor-Antagonisten zur Behandlung von Endometriose
RU2339392C1 (ru) * 2007-05-21 2008-11-27 Федеральное Государственное учреждение Научный центр акушерства, гинекологии и перинатологии Росмедтехнологий Способ остановки маточных кровотечений в пубертатном периоде
AU2010260885B2 (en) * 2009-06-17 2015-03-12 Keio University Prophylactic and/or therapeutic agent for dysmenorrhea
US8399432B2 (en) * 2009-10-27 2013-03-19 Lipogen Ltd. Compositions and methods of treatment for alleviating premenstrual syndrome symptoms
US20220339176A1 (en) * 2019-09-23 2022-10-27 The Board Of Trustees Of The Leland Stanford Junior University Methods of Treatments to Prolong Gestation and Complications of Menstruation or Gestation
US12426782B2 (en) 2020-11-06 2025-09-30 The Board Of Trustees Of The Leland Stanford Junior University Systems and temporal alignment methods for evaluation of gestational age and time to delivery

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3633244A1 (de) 1986-09-26 1988-03-31 Schering Ag Antigestagene zur hemmung der uterinen prostaglandinsynthese
DE4332284C2 (de) 1993-09-20 1997-05-28 Jenapharm Gmbh 11-Benzaldoxim-17beta-methoxy-17alpha-methoxymethyl-estradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE4332283A1 (de) * 1993-09-20 1995-04-13 Jenapharm Gmbh Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US5681817A (en) * 1994-02-04 1997-10-28 The Medical College Of Hampton Roads Treatment of ovarian estrogen dependent conditions
US5576310A (en) * 1994-09-20 1996-11-19 Jenapharm Gmbh 11-benzaldoxime-17β-methoxy-17α-methoxymethyl-estrasdiene derivatives, methods for their production and pharmaceuticals containing such compounds
WO1996019458A2 (fr) * 1994-12-22 1996-06-27 Ligand Pharmaceuticals Incorporated Composes modulateurs des recepteurs des steroides et procedes d'utilisation
US5696130A (en) * 1994-12-22 1997-12-09 Ligand Pharmaceuticals Incorporated Tricyclic steroid receptor modulator compounds and methods
SK282570B6 (sk) 1995-02-02 2002-10-08 Schering Aktiengesellschaft Antagonisty progesterónu na výrobu liekov na ošetrenie dysfunkčného maternicového krvácania
DE19604231A1 (de) * 1996-01-29 1997-07-31 Schering Ag Pharmazeutisches Kombinationspräparat und seine Verwendung zur Behandlung von gynäkologischen Störungen
DE69702450T2 (de) * 1996-05-01 2001-03-08 The Government Of The United States Of America As Represented By The Secretary Of National Institute Of Health, Office Of Technology Transfer 21-substituierte progesteron derivate als antigestagene
WO1998005679A2 (fr) * 1996-08-05 1998-02-12 Duke University Antagonistes mixtes du recepteur progesterone et techniques de dosage associees
DE19809845A1 (de) * 1998-03-03 1999-09-09 Jenapharm Gmbh S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
BR9916999A (pt) * 1999-01-14 2001-10-30 Bayer Ag Heterociclos de 2-arilimino substituìdos ecomposições contendo-os, para uso como agentesde ligação do receptor de progesterona
WO2000066590A2 (fr) * 1999-05-04 2000-11-09 Ligand Pharmaceuticals, Inc. Composes modulateurs de recepteur de progesterone tetracycliques et procedes

Also Published As

Publication number Publication date
HUP0202429A2 (en) 2002-10-28
JP2003535029A (ja) 2003-11-25
YU14002A (sh) 2006-01-16
BG65817B1 (bg) 2010-01-29
AR025457A1 (es) 2002-11-27
SK287192B6 (sk) 2010-02-08
SI20852A (sl) 2002-10-31
ES2295050T3 (es) 2008-04-16
EE200200104A (et) 2003-04-15
LT2002031A (en) 2003-02-25
KR100864547B1 (ko) 2008-10-20
AU781840B2 (en) 2005-06-16
MXPA02002191A (es) 2002-09-30
NZ517471A (en) 2004-02-27
EA200200282A1 (ru) 2002-10-31
PE20010578A1 (es) 2001-06-04
UA78184C2 (en) 2007-03-15
MEP13808A (en) 2010-06-10
NO20020999D0 (no) 2002-02-28
ATE375160T1 (de) 2007-10-15
KR20080066095A (ko) 2008-07-15
SI20852B (sl) 2009-06-30
SK2992002A3 (en) 2002-07-02
KR100755109B1 (ko) 2007-09-04
PL353930A1 (en) 2003-12-15
WO2001015679A3 (fr) 2001-11-22
LT5034B (lt) 2003-07-25
CA2382580A1 (fr) 2001-03-08
HUP0202429A3 (en) 2004-04-28
DE60036723T2 (de) 2008-07-17
EA007854B1 (ru) 2007-02-27
CO5200772A1 (es) 2002-09-27
DE60036723D1 (de) 2007-11-22
DK1229906T3 (da) 2008-02-11
NO20020999L (no) 2002-03-14
CA2382580C (fr) 2009-05-19
BR0014161A (pt) 2002-05-21
WO2001015679A2 (fr) 2001-03-08
EP1229906B1 (fr) 2007-10-10
IL148416A0 (en) 2002-09-12
BG106442A (bg) 2002-09-30
CZ2002704A3 (cs) 2003-02-12
HRP20020267A2 (en) 2004-04-30
RS50283B (sr) 2009-09-08
KR20020027616A (ko) 2002-04-13
PL198790B1 (pl) 2008-07-31
EE05172B1 (et) 2009-06-15
EP1229906A2 (fr) 2002-08-14
RO122179B1 (ro) 2009-02-27
AU6946600A (en) 2001-03-26
KR20070058023A (ko) 2007-06-07
PT1229906E (pt) 2008-01-18

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