MA20150421A1 - Procédé et système pour l'administration d'un surfactant pulmonaire par atomisation - Google Patents

Procédé et système pour l'administration d'un surfactant pulmonaire par atomisation

Info

Publication number
MA20150421A1
MA20150421A1 MA37431A MA37431A MA20150421A1 MA 20150421 A1 MA20150421 A1 MA 20150421A1 MA 37431 A MA37431 A MA 37431A MA 37431 A MA37431 A MA 37431A MA 20150421 A1 MA20150421 A1 MA 20150421A1
Authority
MA
Morocco
Prior art keywords
present
delivery
preferred
catheter
pulmonary surfactant
Prior art date
Application number
MA37431A
Other languages
English (en)
Other versions
MA37431B1 (fr
Inventor
Raffaele Dellaca
Ilaria Milesi
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48083209&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA20150421(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of MA20150421A1 publication Critical patent/MA20150421A1/fr
Publication of MA37431B1 publication Critical patent/MA37431B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/03—Measuring fluid pressure within the body other than blood pressure, e.g. cerebral pressure ; Measuring pressure in body tissues or organs
    • A61B5/036—Measuring fluid pressure within the body other than blood pressure, e.g. cerebral pressure ; Measuring pressure in body tissues or organs by means introduced into body tracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0057—Pumps therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes operated by electrical means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A61M16/0475—Tracheal tubes having openings in the tube
    • A61M16/0477—Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids
    • A61M16/0484—Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids at the distal end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A61M16/0486—Multi-lumen tracheal tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/087—Measuring breath flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/091—Measuring volume of inspired or expired gases, e.g. to determine lung capacity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7242—Details of waveform analysis using integration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A61M16/0461—Nasoendotracheal tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A61M16/106—Filters in a path
    • A61M16/107—Filters in a path in the inspiratory path
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026—Multi-lumen catheters with stationary elements
    • A61M2025/004—Multi-lumen catheters with stationary elements characterized by lumina being arranged circumferentially
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0468—Liquids non-physiological
    • A61M2202/0488—Surfactant, e.g. for the lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3348—Pressure measurement using a water column
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/005—Anatomical parts of the body used as an access side to the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0618—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0625—Mouth
    • A61M2210/065—Throat; Pharynx
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2240/00—Specially adapted for neonatal use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026—Multi-lumen catheters with stationary elements
    • A61M25/003—Multi-lumen catheters with stationary elements characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Le procédé et le système selon les modes de réalisation préférés de la présente invention permettent d'optimiser l'administration de médicaments en aérosol. En particulier, le système selon un mode de réalisation préféré de la présente invention permet l'administration d'un surfactant pulmonaire exogène à des patients très jeunes (par exemple, des nouveaux-nés prématurés). Un cathéter (101) transfère un surfactant atomisé directement dans la région rétro-pharyngée afin d'augmenter l'efficacité de l'administration de médicament sans être invasif : ceci est particulièrement important pour les patients très jeunes, tels que les nouveaux-nés prématurés souffrant du syndrome de détresse respiratoire du nouveau-né (nrds). Il est possible d'accoupler le cathéter à un échafaudage rigide (par exemple, métallique) pour accroître la rigidité du dispositif et améliorer la facilité des opérations de positionnement. Dans un mode de réalisation préféré de la présente invention, l'administration du médicament atomisé est réalisée au moyen d'une technique de projection par air forcé.
MA37431A 2012-04-23 2013-04-12 Procédé et système pour l'administration d'un surfactant pulmonaire par atomisation MA37431B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12165234 2012-04-23
PCT/EP2013/057744 WO2013160129A1 (fr) 2012-04-23 2013-04-12 Procédé et système pour l'administration d'un surfactant pulmonaire par atomisation

Publications (2)

Publication Number Publication Date
MA20150421A1 true MA20150421A1 (fr) 2015-11-30
MA37431B1 MA37431B1 (fr) 2016-06-30

Family

ID=48083209

Family Applications (1)

Application Number Title Priority Date Filing Date
MA37431A MA37431B1 (fr) 2012-04-23 2013-04-12 Procédé et système pour l'administration d'un surfactant pulmonaire par atomisation

Country Status (24)

Country Link
US (1) US10456538B2 (fr)
EP (1) EP2841135B1 (fr)
JP (1) JP6293732B2 (fr)
KR (1) KR102051677B1 (fr)
CN (1) CN104321103B (fr)
AR (1) AR090811A1 (fr)
AU (1) AU2013251865B2 (fr)
BR (1) BR112014026212A8 (fr)
CA (1) CA2870391A1 (fr)
CL (1) CL2014002863A1 (fr)
CO (1) CO7160044A2 (fr)
EA (1) EA027030B1 (fr)
ES (1) ES2616082T3 (fr)
IL (1) IL235143A0 (fr)
IN (1) IN2014DN09602A (fr)
MA (1) MA37431B1 (fr)
MX (1) MX351677B (fr)
NZ (1) NZ701073A (fr)
PE (1) PE20150604A1 (fr)
PH (1) PH12014502321A1 (fr)
SG (1) SG11201406628RA (fr)
TN (1) TN2014000429A1 (fr)
WO (1) WO2013160129A1 (fr)
ZA (1) ZA201407557B (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201609206A (zh) * 2013-10-22 2016-03-16 奇希製藥公司 藉由霧化投予肺部表面活性劑之改良方法及系統
US11291780B2 (en) * 2014-12-04 2022-04-05 Vyaire Medical Consumables Llc Breath-actuated nebulizer for medicine inhalation
US10646669B2 (en) 2014-12-29 2020-05-12 Ony Biotech Inc. Aerosol medication delivery system and method
US12521508B2 (en) 2015-01-13 2026-01-13 Trudell Medical International Inc. Respiratory interface
ES2901761T3 (es) 2015-01-13 2022-03-23 Trudell Medical Int Interfaz respiratoria
US20180110948A1 (en) * 2015-04-22 2018-04-26 Chiesi Farmaceutici S.P.A Method and system for effective breath-synchronized delivery of medicament to the lungs
EP3106090A1 (fr) 2015-06-15 2016-12-21 CHIESI FARMACEUTICI S.p.A. Système pour une administration efficace, synchronisée avec la respiration, d'un médicament aux poumons
WO2016173634A1 (fr) 2015-04-28 2016-11-03 Chiesi Farmaceutici S.P.A Dispositif permettant de faciliter l'administration d'un médicament aux poumons par l'intermédiaire d'un cathéter
MX2017013235A (es) * 2015-04-28 2018-05-22 Chiesi Farm Spa Dispositivo para facilitar la administracion de un medicamento al pulmon mediante un catéter.
WO2017086939A1 (fr) * 2015-11-17 2017-05-26 Flosure Technologies Llc Dispositif trachéal ou endotrachéal comportant un système intégré d'élimination des sécrétions infectieuses
EP3407844A4 (fr) * 2016-01-29 2019-10-16 Qool Therapeutics, Inc. Aérosolisation de cellules souches ou de dérivés de cellule souche destinée à une administration pulmonaire
KR101861078B1 (ko) * 2016-03-29 2018-05-28 (주)엘메카 네트워크를 통한 의료용 석션기의 관리 방법 및 이에 사용되는 관리 서버
MA45772A (fr) 2016-07-28 2021-04-28 Chiesi Farm Spa Procédé et système d'administration d'un médicament sous forme d'aérosol
AU2017349790A1 (en) * 2016-10-26 2019-05-02 Chiesi Farmaceutici S.P.A. Device for facilitating the administration of a medicament to the lung by a catheter
US11027077B2 (en) 2017-03-23 2021-06-08 Stamford Devices Ltd. Aerosol delivery system and method
AU2018240522B2 (en) * 2017-03-23 2023-07-06 Stamford Devices Ltd Aerosol delivery system and method
KR20200095472A (ko) * 2017-11-10 2020-08-10 디펜신 테라퓨틱스 에이피에스 조산아에서의 점막 방어 및 장/폐 기능의 성숙화
JP7378425B2 (ja) * 2018-04-23 2023-11-13 シエシー ファルマセウティチィ ソシエタ ペル アチオニ 肺サーファクタントおよびｂｐｄの予防のためのステロイドを含む治療的組合せ
CN109745601B (zh) * 2019-01-11 2024-10-15 广州瑞普医疗科技有限公司 雾化过程监测方法、系统、计算机设备、存储介质及装置
US20230062996A1 (en) * 2019-10-11 2023-03-02 Rocket Science Health Corp. Intranasal drug delivery device, system, and process
FR3105004B1 (fr) * 2019-12-18 2023-10-27 Univ Bordeaux Cathéter pour l’administration d’une pulverisation médicamenteuse dans la trachée d’un sujet
US11771132B2 (en) 2020-08-27 2023-10-03 Rai Strategic Holdings, Inc. Atomization nozzle for aerosol delivery device
US20230364355A1 (en) * 2020-09-28 2023-11-16 Vectura Delivery Devices Limited Inhalation device
GB2618256B (en) * 2020-12-30 2025-07-09 Hexarhumancare Co Ltd Exoskeleton-type rehabilitation robot system
WO2022154138A1 (fr) * 2021-01-13 2022-07-21 (주)앰틱스바이오 Dispositif de pulvérisation de matériau de pansement pour ulcère gastroduodénal
CN219721561U (zh) * 2022-05-26 2023-09-22 杭州堃博生物科技有限公司 一种雾化设备以及雾化系统
KR20250172196A (ko) * 2024-05-31 2025-12-09 고려대학교 산학협력단 폐 계면활성제 및 항섬유화제를 포함하는 폐섬유증의 예방 또는 치료용 조성물 및 이의 제조방법

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US692273A (en) * 1901-03-16 1902-02-04 Edward J Gulick Desk-support.
DE3206482C2 (de) * 1982-02-23 1984-03-15 Drägerwerk AG, 2400 Lübeck Beatmungsvorrichtung mit einer Einrichtung zur Sicherheitsüberwachung
US4813431A (en) * 1987-07-22 1989-03-21 David Brown Intrapulmonary pressure monitoring system
GB9307733D0 (en) * 1993-04-14 1993-06-02 Msa Britain Ltd Respiratory protective device
EP0758257B1 (fr) * 1994-05-06 2000-02-23 Mark Brauner Appareil pour la therapie intrapulmonaire et l'administration de medicaments
US5803078A (en) * 1994-05-06 1998-09-08 Brauner; Mark E. Methods and apparatus for intrapulmonary therapy and drug administration
ZA954936B (en) * 1994-06-17 1996-02-27 Trudell Medical Ltd Nebulizing catheter system and methods of use and manufacture
WO1999030833A1 (fr) * 1997-12-17 1999-06-24 Universidad De Sevilla Dispositif et procede pour creer des particules seches
IT1308180B1 (it) * 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
US6315739B1 (en) * 1999-09-27 2001-11-13 Instrumentarium Corporation Apparatus and method for measuring the intratracheal pressure of an intubated patient
SE0203591D0 (sv) * 2002-12-04 2002-12-04 Siemens Elema Ab Förfarande för beredning av ett mediakament och en medicinsk anordning
US7267121B2 (en) * 2004-04-20 2007-09-11 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
BRPI0509991A (pt) * 2004-04-20 2007-10-16 Aerogen Inc aparelho de fornecimento em aerossol, métodos e composições para sistemas de respiração auxiliados por pressão
DE102006006183A1 (de) * 2006-02-10 2007-08-16 Pari GmbH Spezialisten für effektive Inhalation Inhalationstherapievorrichtung für die Anwendung bei Frühgeborenen und Kleinkindern
CN2905088Y (zh) * 2006-04-10 2007-05-30 陈清甫 便携式雾化给药装置
US8303531B2 (en) * 2008-02-11 2012-11-06 Nordson Corporation Spray applicator with positionable spray tip
PL2265309T3 (pl) * 2008-03-17 2016-06-30 Discovery Lab Inc Adapter obwodu oddechowego i proksymalny system podawania aerozolu
PL2110126T3 (pl) * 2008-04-18 2012-04-30 Novaliq Gmbh Zastosowanie do inhalacji i zakraplania semifluorowanych alkanów jako nośników substancji aktywnych w strefie wewnątrzpłucnej
DE102010025045B4 (de) * 2010-06-22 2016-11-03 Frank Jochum Vorrichtung zur Gabe von Surfactant
CN107293314B (zh) * 2016-03-31 2019-03-12 光宝电子(广州)有限公司 托盘刹车装置

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MX351677B (es) 2017-10-25
BR112014026212A8 (pt) 2019-12-24
NZ701073A (en) 2016-04-29
CL2014002863A1 (es) 2015-04-10
EA027030B1 (ru) 2017-06-30
JP6293732B2 (ja) 2018-03-14
IN2014DN09602A (fr) 2015-07-31
EP2841135A1 (fr) 2015-03-04
EA201491812A1 (ru) 2015-02-27
CN104321103B (zh) 2017-04-26
JP2015514481A (ja) 2015-05-21
WO2013160129A1 (fr) 2013-10-31
PH12014502321A1 (en) 2015-01-12
ES2616082T3 (es) 2017-06-09
US20130333695A1 (en) 2013-12-19
MA37431B1 (fr) 2016-06-30
MX2014012368A (es) 2015-05-11
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ZA201407557B (en) 2016-08-31
IL235143A0 (en) 2014-12-31
CN104321103A (zh) 2015-01-28
CA2870391A1 (fr) 2013-10-31
EP2841135B1 (fr) 2016-12-14
BR112014026212A2 (pt) 2017-06-27
AU2013251865B2 (en) 2017-02-16
KR102051677B1 (ko) 2019-12-03
KR20150004832A (ko) 2015-01-13
AR090811A1 (es) 2014-12-10
SG11201406628RA (en) 2014-11-27
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US10456538B2 (en) 2019-10-29

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