MA37431B1 - Procédé et système pour l'administration d'un surfactant pulmonaire par atomisation - Google Patents

Procédé et système pour l'administration d'un surfactant pulmonaire par atomisation

Info

Publication number
MA37431B1
MA37431B1 MA37431A MA37431A MA37431B1 MA 37431 B1 MA37431 B1 MA 37431B1 MA 37431 A MA37431 A MA 37431A MA 37431 A MA37431 A MA 37431A MA 37431 B1 MA37431 B1 MA 37431B1
Authority
MA
Morocco
Prior art keywords
present
preferred
catheter
administration
pulmonary surfactant
Prior art date
Application number
MA37431A
Other languages
Arabic (ar)
English (en)
Other versions
MA20150421A1 (fr
Inventor
Raffaele Dellaca
Ilaria Milesi
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48083209&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA37431(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of MA20150421A1 publication Critical patent/MA20150421A1/fr
Publication of MA37431B1 publication Critical patent/MA37431B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/03—Measuring fluid pressure within the body other than blood pressure, e.g. cerebral pressure ; Measuring pressure in body tissues or organs
    • A61B5/036—Measuring fluid pressure within the body other than blood pressure, e.g. cerebral pressure ; Measuring pressure in body tissues or organs by means introduced into body tracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0057—Pumps therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes operated by electrical means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A61M16/0475—Tracheal tubes having openings in the tube
    • A61M16/0477—Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids
    • A61M16/0484—Tracheal tubes having openings in the tube with incorporated means for delivering or removing fluids at the distal end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A61M16/0486—Multi-lumen tracheal tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/087—Measuring breath flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/091—Measuring volume of inspired or expired gases, e.g. to determine lung capacity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7242—Details of waveform analysis using integration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A61M16/0461—Nasoendotracheal tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A61M16/106—Filters in a path
    • A61M16/107—Filters in a path in the inspiratory path
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026—Multi-lumen catheters with stationary elements
    • A61M2025/004—Multi-lumen catheters with stationary elements characterized by lumina being arranged circumferentially
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0468—Liquids non-physiological
    • A61M2202/0488—Surfactant, e.g. for the lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3348—Pressure measurement using a water column
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/005—Anatomical parts of the body used as an access side to the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0618—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0625—Mouth
    • A61M2210/065—Throat; Pharynx
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2240/00—Specially adapted for neonatal use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026—Multi-lumen catheters with stationary elements
    • A61M25/003—Multi-lumen catheters with stationary elements characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Le procédé et le système selon les modes de réalisation préférés de la présente invention permettent d'optimiser l'administration de médicaments en aérosol. En particulier, le système selon un mode de réalisation préféré de la présente invention permet l'administration d'un surfactant pulmonaire exogène à des patients très jeunes (par exemple, des nouveaux-nés prématurés). Un cathéter (101) transfère un surfactant atomisé directement dans la région rétro-pharyngée afin d'augmenter l'efficacité de l'administration de médicament sans être invasif : ceci est particulièrement important pour les patients très jeunes, tels que les nouveaux-nés prématurés souffrant du syndrome de détresse respiratoire du nouveau-né (nrds). Il est possible d'accoupler le cathéter à un échafaudage rigide (par exemple, métallique) pour accroître la rigidité du dispositif et améliorer la facilité des opérations de positionnement. Dans un mode de réalisation préféré de la présente invention, l'administration du médicament atomisé est réalisée au moyen d'une technique de projection par air forcé.
MA37431A 2012-04-23 2013-04-12 Procédé et système pour l'administration d'un surfactant pulmonaire par atomisation MA37431B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12165234 2012-04-23
PCT/EP2013/057744 WO2013160129A1 (fr) 2012-04-23 2013-04-12 Procédé et système pour l'administration d'un surfactant pulmonaire par atomisation

Publications (2)

Publication Number Publication Date
MA20150421A1 MA20150421A1 (fr) 2015-11-30
MA37431B1 true MA37431B1 (fr) 2016-06-30

Family

ID=48083209

Family Applications (1)

Application Number Title Priority Date Filing Date
MA37431A MA37431B1 (fr) 2012-04-23 2013-04-12 Procédé et système pour l'administration d'un surfactant pulmonaire par atomisation

Country Status (24)

Country Link
US (1) US10456538B2 (fr)
EP (1) EP2841135B1 (fr)
JP (1) JP6293732B2 (fr)
KR (1) KR102051677B1 (fr)
CN (1) CN104321103B (fr)
AR (1) AR090811A1 (fr)
AU (1) AU2013251865B2 (fr)
BR (1) BR112014026212A8 (fr)
CA (1) CA2870391A1 (fr)
CL (1) CL2014002863A1 (fr)
CO (1) CO7160044A2 (fr)
EA (1) EA027030B1 (fr)
ES (1) ES2616082T3 (fr)
IL (1) IL235143A0 (fr)
IN (1) IN2014DN09602A (fr)
MA (1) MA37431B1 (fr)
MX (1) MX351677B (fr)
NZ (1) NZ701073A (fr)
PE (1) PE20150604A1 (fr)
PH (1) PH12014502321A1 (fr)
SG (1) SG11201406628RA (fr)
TN (1) TN2014000429A1 (fr)
WO (1) WO2013160129A1 (fr)
ZA (1) ZA201407557B (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201609206A (zh) * 2013-10-22 2016-03-16 奇希製藥公司 藉由霧化投予肺部表面活性劑之改良方法及系統
WO2016089981A1 (fr) * 2014-12-04 2016-06-09 Carefusion 2200, Inc. Nébuliseur actionné par la respiration pour l'inhalation de médicament
CA2972596C (fr) 2014-12-29 2023-06-20 Edmund A. Egan Systeme et procede d'administration de medicament sous forme d'aerosol
US12521508B2 (en) 2015-01-13 2026-01-13 Trudell Medical International Inc. Respiratory interface
PL3244950T3 (pl) 2015-01-13 2022-04-04 Trudell Medical International Interfejs oddechowy
EP3106090A1 (fr) 2015-06-15 2016-12-21 CHIESI FARMACEUTICI S.p.A. Système pour une administration efficace, synchronisée avec la respiration, d'un médicament aux poumons
EP3285645B1 (fr) 2015-04-22 2020-08-12 Chiesi Farmaceutici S.p.A. Système pour une administration efficace, synchronisée avec la respiration, d'un médicament aux poumons
US11311691B2 (en) * 2015-04-28 2022-04-26 Chiesi Farmaceutici S.P.A Device for facilitating the administration of a medicament to the lung by a catheter
BR112017022984A2 (pt) * 2015-04-28 2018-07-24 Chiesi Farmaceutici S.P.A. dispositivo para facilitar o posicionamento de um cateter para administrar um medicamento em um paciente que esteja respirando espontaneamente
WO2017086939A1 (fr) * 2015-11-17 2017-05-26 Flosure Technologies Llc Dispositif trachéal ou endotrachéal comportant un système intégré d'élimination des sécrétions infectieuses
EP3407844A4 (fr) * 2016-01-29 2019-10-16 Qool Therapeutics, Inc. Aérosolisation de cellules souches ou de dérivés de cellule souche destinée à une administration pulmonaire
KR101861078B1 (ko) * 2016-03-29 2018-05-28 (주)엘메카 네트워크를 통한 의료용 석션기의 관리 방법 및 이에 사용되는 관리 서버
US11207475B2 (en) * 2016-07-28 2021-12-28 Chiesi Farmaceutici S.P.A Method and system for delivery of an aerosolized medicament
AU2017349790A1 (en) 2016-10-26 2019-05-02 Chiesi Farmaceutici S.P.A. Device for facilitating the administration of a medicament to the lung by a catheter
ES2987903T3 (es) * 2017-03-23 2024-11-18 Stamford Devices Ltd Sistema de administración de aerosol
US11027077B2 (en) 2017-03-23 2021-06-08 Stamford Devices Ltd. Aerosol delivery system and method
MX2020004863A (es) * 2017-11-10 2020-10-14 Defensin Therapeutics Aps Maduracion de la defensa de la mucosa y/o funcion intestinal/pulmonar en el bebe prematuro.
KR102781186B1 (ko) * 2018-04-23 2025-03-17 키에시 파르마슈티시 엣스. 피. 에이. Bpd의 예방을 위한 폐 계면활성제 및 스테로이드를 포함하는 치료학적 조합물
CN109745601B (zh) * 2019-01-11 2024-10-15 广州瑞普医疗科技有限公司 雾化过程监测方法、系统、计算机设备、存储介质及装置
US20230062996A1 (en) * 2019-10-11 2023-03-02 Rocket Science Health Corp. Intranasal drug delivery device, system, and process
US11771132B2 (en) 2020-08-27 2023-10-03 Rai Strategic Holdings, Inc. Atomization nozzle for aerosol delivery device
WO2022064041A1 (fr) * 2020-09-28 2022-03-31 Vectura Delivery Devices Limited Dispositif d'inhalation
WO2022145915A1 (fr) * 2020-12-30 2022-07-07 주식회사 헥사휴먼케어 Système de robot de rééducation de type exosquelette
WO2022154138A1 (fr) * 2021-01-13 2022-07-21 (주)앰틱스바이오 Dispositif de pulvérisation de matériau de pansement pour ulcère gastroduodénal
KR20250172196A (ko) * 2024-05-31 2025-12-09 고려대학교 산학협력단 폐 계면활성제 및 항섬유화제를 포함하는 폐섬유증의 예방 또는 치료용 조성물 및 이의 제조방법

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US692273A (en) * 1901-03-16 1902-02-04 Edward J Gulick Desk-support.
DE3206482C2 (de) * 1982-02-23 1984-03-15 Drägerwerk AG, 2400 Lübeck Beatmungsvorrichtung mit einer Einrichtung zur Sicherheitsüberwachung
US4813431A (en) * 1987-07-22 1989-03-21 David Brown Intrapulmonary pressure monitoring system
GB9307733D0 (en) * 1993-04-14 1993-06-02 Msa Britain Ltd Respiratory protective device
US5803078A (en) * 1994-05-06 1998-09-08 Brauner; Mark E. Methods and apparatus for intrapulmonary therapy and drug administration
EP0758257B1 (fr) * 1994-05-06 2000-02-23 Mark Brauner Appareil pour la therapie intrapulmonaire et l'administration de medicaments
IL114154A0 (en) * 1994-06-17 1995-10-31 Trudell Medical Ltd Nebulizing catheter system and methods of use and manufacture
EP1037713B1 (fr) * 1997-12-17 2002-07-10 Universidad de Sevilla Procede de production de gouttelettes creuses
IT1308180B1 (it) * 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
US6315739B1 (en) * 1999-09-27 2001-11-13 Instrumentarium Corporation Apparatus and method for measuring the intratracheal pressure of an intubated patient
SE0203591D0 (sv) * 2002-12-04 2002-12-04 Siemens Elema Ab Förfarande för beredning av ett mediakament och en medicinsk anordning
US7267121B2 (en) * 2004-04-20 2007-09-11 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
AU2005234774B2 (en) * 2004-04-20 2011-01-20 Novartis Ag Aerosol delivery apparatus for pressure assisted breathing
DE102006006183A1 (de) * 2006-02-10 2007-08-16 Pari GmbH Spezialisten für effektive Inhalation Inhalationstherapievorrichtung für die Anwendung bei Frühgeborenen und Kleinkindern
CN2905088Y (zh) * 2006-04-10 2007-05-30 陈清甫 便携式雾化给药装置
US8303531B2 (en) * 2008-02-11 2012-11-06 Nordson Corporation Spray applicator with positionable spray tip
ES2565219T3 (es) * 2008-03-17 2016-04-01 Discovery Laboratories, Inc. Adaptador de circuito de ventilación y sistema proximal de administración de aerosol
ES2377152T3 (es) * 2008-04-18 2012-03-22 Novaliq Gmbh Uso inhalativo e instilativo de alcanos semifluorados como vehículos de principios activos en la región intrapulmonar
DE102010025045B4 (de) * 2010-06-22 2016-11-03 Frank Jochum Vorrichtung zur Gabe von Surfactant
CN107293314B (zh) * 2016-03-31 2019-03-12 光宝电子(广州)有限公司 托盘刹车装置

Also Published As

Publication number Publication date
CL2014002863A1 (es) 2015-04-10
EA027030B1 (ru) 2017-06-30
EA201491812A1 (ru) 2015-02-27
TN2014000429A1 (en) 2016-03-30
MX351677B (es) 2017-10-25
IN2014DN09602A (fr) 2015-07-31
US20130333695A1 (en) 2013-12-19
CN104321103A (zh) 2015-01-28
NZ701073A (en) 2016-04-29
JP2015514481A (ja) 2015-05-21
EP2841135A1 (fr) 2015-03-04
BR112014026212A8 (pt) 2019-12-24
EP2841135B1 (fr) 2016-12-14
KR102051677B1 (ko) 2019-12-03
ES2616082T3 (es) 2017-06-09
KR20150004832A (ko) 2015-01-13
CA2870391A1 (fr) 2013-10-31
ZA201407557B (en) 2016-08-31
AU2013251865A1 (en) 2014-11-06
US10456538B2 (en) 2019-10-29
WO2013160129A1 (fr) 2013-10-31
AR090811A1 (es) 2014-12-10
SG11201406628RA (en) 2014-11-27
MX2014012368A (es) 2015-05-11
PE20150604A1 (es) 2015-06-07
MA20150421A1 (fr) 2015-11-30
CN104321103B (zh) 2017-04-26
PH12014502321A1 (en) 2015-01-12
JP6293732B2 (ja) 2018-03-14
IL235143A0 (en) 2014-12-31
AU2013251865B2 (en) 2017-02-16
HK1205474A1 (en) 2015-12-18
CO7160044A2 (es) 2015-01-15
BR112014026212A2 (pt) 2017-06-27

Similar Documents

Publication Publication Date Title
MA37431B1 (fr) Procédé et système pour l'administration d'un surfactant pulmonaire par atomisation
Kim et al. The crucial role of the blood–brain barrier in neurodegenerative diseases: mechanisms of disruption and therapeutic implications
Choi et al. Diverse immunoregulatory roles of oxysterols—the oxidized cholesterol metabolites
Olliaro et al. The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer)
Kamenshchikov et al. Therapeutic effects of inhaled nitric oxide therapy in COVID-19 patients
MA50205B1 (fr) Formulation de nicotine
Peng et al. Therapeutic time window and dose dependence of xenon delivered via echogenic liposomes for neuroprotection in stroke
JP2026027384A (ja) 細気管支炎を有する乳幼児のための一酸化窒素吸入療法
Jonkman et al. Ketamine inhalation
Landis et al. Nasal-to-CNS drug delivery: where are we now and where are we heading? An industrial perspective
MA34449B1 (fr) Formulation de poudre seche comprenant un inhibiteur de phosphodiesterase
To et al. Spatial properties of reactive oxygen species govern pathogen-specific immune system responses
JP2016539921A5 (fr)
TN2014000345A1 (en) Pharmaceutical preparation containing an antivirally active dihydroquinazoline derivative
Nahomi et al. Kynurenic acid protects against ischemia/reperfusion-induced retinal ganglion cell death in mice
de Souza et al. Prodrug approach as a strategy to enhance drug permeability
Worley et al. The metabolism and transplacental transfer of oseltamivir in the ex vivo human model
JP2014515407A5 (fr)
ITMI20122002A1 (it) Preparazioni farmaceutiche liquide stabilizzate
Espehana et al. Delivery of topical drugs to the olfactory cleft
Kumar et al. Prostacyclin and milrinone by aerosolization improve pulmonary hemodynamics in newborn lambs with experimental pulmonary hypertension
PH12022552257A1 (en) Pharmaceutical compositions comprising 2-[(4s)-8-fluoro-2-[4-(3- methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5- (trifluoromethyl)phenyl]-4h-quinazolin-4-yl]acetate and sodium ions
US20130065936A1 (en) Modulation of bioactive epoxy-fatty acid levels by phosphodiesterase inhibitors
Nagao et al. Nonlinear disposition and metabolic interactions of cannabidiol through CYP3A inhibition in vivo in rats
Nakazawa et al. Treatment of pulmonary hypertension and hypoxia due to oleic acid induced lung injury with intratracheal prostaglandin E1 during partial liquid ventilation.