MA24062A1 - Heteroatome comprenant des cyclopentano-pyridile oxazolidinones - Google Patents

Heteroatome comprenant des cyclopentano-pyridile oxazolidinones

Info

Publication number: MA24062A1
Authority: MA; Morocco
Prior art keywords: pyridile; cyclopentano; heteroatome; oxazolidinones; pyridile oxazolidinones
Prior art date: 1996-01-18

Application number

MA24463A

Other languages

English (en)

Inventor

Stolle Andreas

Bartel Stephan

Ruppelt Martin

Kroll Hein-Peter

Endermann Rainer

Habich Dieter

Guarnieri Walter

Riedl Bernd

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-01-18

Filing date

1997-01-14

Publication date

1997-10-01

1997-01-14 Application filed by Bayer Ag filed Critical Bayer Ag

1997-10-01 Publication of MA24062A1 publication Critical patent/MA24062A1/fr

Links

IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical compound O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Molecular Biology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

MA24463A 1996-01-18 1997-01-14 Heteroatome comprenant des cyclopentano-pyridile oxazolidinones MA24062A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19601627A DE19601627A1 (de)	1996-01-18	1996-01-18	Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone

Publications (1)

Publication Number	Publication Date
MA24062A1 true MA24062A1 (fr)	1997-10-01

Family

ID=7783042

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA24463A MA24062A1 (fr)	1996-01-18	1997-01-14	Heteroatome comprenant des cyclopentano-pyridile oxazolidinones

Country Status (21)

Country	Link
US (1)	US5869659A (fr)
EP (1)	EP0785201A1 (fr)
JP (1)	JPH09202787A (fr)
KR (1)	KR970059170A (fr)
AU (1)	AU1012397A (fr)
BG (1)	BG101139A (fr)
BR (1)	BR9700716A (fr)
CA (1)	CA2195177A1 (fr)
CZ (1)	CZ15897A3 (fr)
DE (1)	DE19601627A1 (fr)
EE (1)	EE9700020A (fr)
HU (1)	HU9700152D0 (fr)
IL (1)	IL120016A0 (fr)
MA (1)	MA24062A1 (fr)
NO (1)	NO970210L (fr)
PL (1)	PL317985A1 (fr)
SG (1)	SG50001A1 (fr)
SK (1)	SK6997A3 (fr)
TN (1)	TNSN97010A1 (fr)
TR (1)	TR199700039A2 (fr)
ZA (1)	ZA97393B (fr)

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US6562844B2 (en)	1998-01-23	2003-05-13	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
EP1082323A2 (fr) *	1998-06-05	2001-03-14	AstraZeneca UK Limited	Composes chimiques
CN1367780A (zh)	1999-07-28	2002-09-04	法玛西雅厄普约翰美国公司	噁唑烷酮类化合物、其制备方法及其应用
GB9928568D0 (en)	1999-12-03	2000-02-02	Zeneca Ltd	Chemical compounds
MY127336A (en)	2000-03-22	2006-11-30	Upjohn Co	Container for linezolid iv solution
US6514529B2 (en)	2000-03-22	2003-02-04	Pharmacia & Upjohn Company	Oxazolidinone tablet formulation
GB0009803D0 (en) *	2000-04-25	2000-06-07	Astrazeneca Ab	Chemical compounds
DE60112581T2 (de)	2000-06-30	2006-06-01	Pharmacia & Upjohn Co. Llc, Kalamazoo	Zusammensetzungen zur Behandlung bakterieller Infektionen, welche ein Oxazolidinonderivat, Sulbactam und Ampicillin enthalten
US6423844B1 (en)	2001-06-06	2002-07-23	The United States Of America As Represented By The Secretary Of The Navy	Process for making 1,2,4-triazolo[4,3-a][1,3,5]triazine-3,5,7-triamine
US7141588B2 (en) *	2002-02-25	2006-11-28	Pfizer, Inc.	N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) *	2002-02-25	2005-01-19	Upjohn Co	N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
MXPA05001558A (es) *	2002-08-12	2005-09-08	Pharmacia & Upjohn Co Llc	N-aril-2-oxazolidinonas y sus derivados.
ATE344036T1 (de) *	2002-11-21	2006-11-15	Pharmacia & Upjohn Co Llc	N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinon-5- carbonsäureamid-derivate und verwandte verbindungen als antibakterielle mittel
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US20040204463A1 (en) *	2003-04-01	2004-10-14	Harris Christina Renee	N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
US7304050B2 (en) *	2003-09-16	2007-12-04	Pfizer Inc.	Antibacterial agents
WO2005082900A2 (fr) *	2004-01-28	2005-09-09	Pharmacia & Upjohn Company Llc	Amidoxines d'oxazolidinone utilisees en tant qu'agents antibacteriens
US20080262056A1 (en) *	2004-08-06	2008-10-23	Pfizer Inc	Oxindole Oxazolidinones as Antibacterial Agents
ES2627352T3 (es) *	2006-10-19	2017-07-27	Signal Pharmaceuticals, Llc	Compuestos heteroarilo, sus composiciones y su uso como inhibidores de proteínas quinasas
US8110578B2 (en)	2008-10-27	2012-02-07	Signal Pharmaceuticals, Llc	Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway
NZ599549A (en)	2009-10-26	2013-11-29	Signal Pharm Llc	Methods of synthesis and purification of heteroaryl compounds
CN103998036B (zh)	2011-10-19	2017-05-31	西格诺药品有限公司	利用tor激酶抑制剂治疗癌症
BR112014013332B1 (pt)	2011-12-02	2022-09-06	Signal Pharmaceuticals, Llc	Composições farmacêuticas de 7-(6-(2-hidroxi-propan-2-il)piridin-3-il)-1-((trans)-4- metoxicicloexil)-3,4-diidropirazino [2,3-b]pirazin-2(1h)-ona, uma forma sólida dessa e métodos de seu uso
CN104271159B (zh)	2012-02-24	2017-11-28	西格诺药品有限公司	利用tor激酶抑制剂联合治疗来治疗非小细胞肺癌的方法
AU2013203714B2 (en)	2012-10-18	2015-12-03	Signal Pharmaceuticals, Llc	Inhibition of phosphorylation of PRAS40, GSK3-beta or P70S6K1 as a marker for TOR kinase inhibitory activity
SG11201505446WA (en)	2013-01-16	2015-08-28	Signal Pharm Llc	Substituted pyrrolopyrimidine compounds, compositions thereof, and methods of treatment therewith
HK1221168A1 (zh)	2013-04-17	2017-05-26	西格诺药品有限公司	用於治疗癌症的包括tor激酶抑制剂和n-(3-(5-氟-2-(4-(2-甲氧基乙氧基)苯基氨基)嘧啶-4-基氨基)苯基)丙烯醯胺的组合疗法
WO2014172436A1 (fr)	2013-04-17	2014-10-23	Signal Pharmaceuticals, Llc	Polythérapie comprenant un inhibiteur de kinase tor et un composé de quinazolinone substitué en 5 pour le traitement du cancer
CA2908742C (fr)	2013-04-17	2021-06-01	Signal Pharmaceuticals, Llc	Polytherapie comprenant un inhibiteur de la kinase tor et un analogue de la cytidine pour le traitement du cancer
MY189663A (en)	2013-04-17	2022-02-23	Signal Pharm Llc	Combination therapy comprising a dihydropyrazino-pyrazine compound and an androgen receptor antagonist for treating prostate cancer
WO2014172425A1 (fr)	2013-04-17	2014-10-23	Signal Pharmaceuticals, Llc	Traitement du cancer par des dihydropyrazino-pyrazines
JP6382946B2 (ja)	2013-04-17	2018-08-29	シグナルファーマシューティカルズ，エルエルシー	ジヒドロピラジノ−ピラジンによる癌治療
EP3549940A1 (fr)	2013-04-17	2019-10-09	Signal Pharmaceuticals, LLC	Formulations pharmaceutiques associés à 1-éthyl-7-(2-méthyl-6-(1h-1,2,4-triazol-3-yl) pyridin-3-yl) -3,4-dihydropyrazino[2,3-b]pyrazin-2(1h)-one
CN107474051B (zh)	2013-05-29	2020-10-30	西格诺药品有限公司	二氢吡嗪并吡嗪化合物的药物组合物、其固体形式和它们的用途
NZ714742A (en)	2014-04-16	2017-04-28	Signal Pharm Llc	Solid forms of 1-ethyl-7-(2-methyl-6-(1h-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1h)-one, compositions thereof and methods of their use
US9718824B2 (en)	2014-04-16	2017-08-01	Signal Pharmaceuticals, Llc	Solid forms comprising 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one, and a coformer, compositions and methods of use thereof
WO2015160880A1 (fr)	2014-04-16	2015-10-22	Signal Pharmaceuticals, Llc	Formes solides comprenant 1-éthyl-7-(2-méthyl-6-(1h-1,2,4-triazol-3-yl) pyridin-3-yl)-3,4-dihydropyrazino(2,3-b)pyrazin-2(1h)-one, et co-formateur, compositions et procédés d'utilisation de ces dernières
EP3131552B1 (fr)	2014-04-16	2020-07-15	Signal Pharmaceuticals, LLC	Méthodes de traitement du cancer à l'aide d'une polythérapie avec des inhibiteurs de la kinase tor
NZ629796A (en)	2014-07-14	2015-12-24	Signal Pharm Llc	Amorphous form of 4-((4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7h-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-3-methoxy-n-methylbenzamide, compositions thereof and methods of their use
WO2016010886A1 (fr)	2014-07-14	2016-01-21	Signal Pharmaceuticals, Llc	Méthodes de traitement d'un cancer à l'aide de composés de pyrrolopyrimidine substitués, compositions de ceux-ci
IL271491B2 (en)	2017-06-22	2023-09-01	Celgene Corp	Treatment of carcinoma of the liver characterized by hepatitis b virus infection

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JP2669579B2 (ja)	1991-10-23	1997-10-29	エーザイ株式会社	オキサゾリドン誘導体
DE4332384A1 (de) *	1993-09-23	1995-03-30	Merck Patent Gmbh	Adhäsionsrezeptor-Antagonisten III
TW286317B (fr)	1993-12-13	1996-09-21	Hoffmann La Roche
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1996
- 1996-01-18 DE DE19601627A patent/DE19601627A1/de not_active Withdrawn
1997
- 1997-01-07 EP EP97100114A patent/EP0785201A1/fr not_active Withdrawn
- 1997-01-10 AU AU10123/97A patent/AU1012397A/en not_active Abandoned
- 1997-01-13 US US08/785,145 patent/US5869659A/en not_active Expired - Fee Related
- 1997-01-14 MA MA24463A patent/MA24062A1/fr unknown
- 1997-01-15 TN TNTNSN97010A patent/TNSN97010A1/fr unknown
- 1997-01-15 SG SG1997000082A patent/SG50001A1/en unknown
- 1997-01-15 CA CA002195177A patent/CA2195177A1/fr not_active Abandoned
- 1997-01-16 IL IL12001697A patent/IL120016A0/xx unknown
- 1997-01-16 PL PL97317985A patent/PL317985A1/xx unknown
- 1997-01-16 EE EE9700020A patent/EE9700020A/xx unknown
- 1997-01-16 BG BG101139A patent/BG101139A/xx unknown
- 1997-01-16 JP JP9017765A patent/JPH09202787A/ja active Pending
- 1997-01-17 SK SK69-97A patent/SK6997A3/sk unknown
- 1997-01-17 TR TR97/00039A patent/TR199700039A2/xx unknown
- 1997-01-17 BR BR9700716A patent/BR9700716A/pt unknown
- 1997-01-17 ZA ZA97393A patent/ZA97393B/xx unknown
- 1997-01-17 HU HU9700152A patent/HU9700152D0/hu unknown
- 1997-01-17 KR KR1019970001266A patent/KR970059170A/ko not_active Withdrawn
- 1997-01-17 NO NO970210A patent/NO970210L/no unknown
- 1997-01-17 CZ CZ97158A patent/CZ15897A3/cs unknown

Also Published As

Publication number	Publication date
EP0785201A1 (fr)	1997-07-23
HU9700152D0 (en)	1997-03-28
BR9700716A (pt)	1998-10-06
DE19601627A1 (de)	1997-07-24
KR970059170A (ko)	1997-08-12
ZA97393B (en)	1997-07-17
JPH09202787A (ja)	1997-08-05
IL120016A0 (en)	1997-04-15
BG101139A (en)	1998-04-30
CZ15897A3 (en)	1997-08-13
TR199700039A2 (tr)	1997-08-21
CA2195177A1 (fr)	1997-07-19
SG50001A1 (en)	1998-06-15
TNSN97010A1 (fr)	2005-03-15
NO970210L (no)	1997-07-21
SK6997A3 (en)	1997-09-10
MX9700388A (es)	1997-07-31
PL317985A1 (en)	1997-07-21
US5869659A (en)	1999-02-09
EE9700020A (et)	1997-08-15
AU1012397A (en)	1997-07-24
NO970210D0 (no)	1997-01-17

Publication	Publication Date	Title
FR2746302B1 (fr)	1998-12-24	Compositions cosmetiques comprenant des nanopigments
DE69721098D1 (de)	2003-05-28	Entwicklungsgerät
DE69720097D1 (de)	2003-04-30	Entwicklungsgerät
BR9700885A (pt)	1998-10-27	Novas oxazolidinonas substituídas
DE69715313D1 (de)	2002-10-17	Entwicklungsgerät
IT1291486B1 (it)	1999-01-11	Corpo portante.
DK0800783T3 (da)	2001-11-05	Gulvrenseapparat
ZA981579B (en)	1999-03-17	Oxazolidinones
FR2718478B1 (fr)	1996-07-05	Plinthe démontable.
DE59710679D1 (de)	2003-10-09	Lüfter
EP0665613A3 (fr)	1997-04-02	Assemblage d'un détecteur démontable.
TR199501336A2 (tr)	1996-06-21	Talim tertibati.
FR2746301B1 (fr)	1998-04-30	Compositions cosmetiques comprenant des nanopigments
FI3488U1 (fi)	1998-07-30	Pitolaite
IT237397Y1 (it)	2000-09-13	Elettrodomestico
EP1008101A4 (fr)	2003-03-26	Support cryptographique
DE69709700D1 (de)	2002-02-21	Kontrastmittel
DE59509813D1 (de)	2001-12-13	Substituierte oxazoline
FR2724100B1 (fr)	1997-09-19	Oreiller de soutien.
FR2716348B1 (fr)	1996-05-03	Coiffe réglable.
IT1287807B1 (it)	1998-08-18	Dispositivo di fissaggio di corpo rotante.
FR2721514B1 (fr)	1996-09-06	Compositions thérapeutiques comprenant des 3-phényl-3-hydroxypipéridines.
ES1035520Y (es)	1997-11-16	Almohada compleja.
ITBO940383A0 (it)	1994-08-03	Apparecchio magneto-terapeutico.
ITSV970017A0 (it)	1997-04-02	Dispositivo sterilizzatore perfezionato.