MA24062A1 - Heteroatome comprenant des cyclopentano-pyridile oxazolidinones - Google Patents

Heteroatome comprenant des cyclopentano-pyridile oxazolidinones

Info

Publication number: MA24062A1
Authority: MA; Morocco
Prior art keywords: pyridile; cyclopentano; heteroatome; oxazolidinones; pyridile oxazolidinones
Prior art date: 1996-01-18

Application number

MA24463A

Other languages

English (en)

Inventor

Stolle Andreas

Bartel Stephan

Ruppelt Martin

Kroll Hein-Peter

Endermann Rainer

Habich Dieter

Guarnieri Walter

Riedl Bernd

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-01-18

Filing date

1997-01-14

Publication date

1997-10-01

1997-01-14 Application filed by Bayer Ag filed Critical Bayer Ag

1997-10-01 Publication of MA24062A1 publication Critical patent/MA24062A1/fr

Links

IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical compound O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

MA24463A 1996-01-18 1997-01-14 Heteroatome comprenant des cyclopentano-pyridile oxazolidinones MA24062A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19601627A DE19601627A1 (de)	1996-01-18	1996-01-18	Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone

Publications (1)

Publication Number	Publication Date
MA24062A1 true MA24062A1 (fr)	1997-10-01

Family

ID=7783042

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA24463A MA24062A1 (fr)	1996-01-18	1997-01-14	Heteroatome comprenant des cyclopentano-pyridile oxazolidinones

Country Status (21)

Country	Link
US (1)	US5869659A (fr)
EP (1)	EP0785201A1 (fr)
JP (1)	JPH09202787A (fr)
KR (1)	KR970059170A (fr)
AU (1)	AU1012397A (fr)
BG (1)	BG101139A (fr)
BR (1)	BR9700716A (fr)
CA (1)	CA2195177A1 (fr)
CZ (1)	CZ15897A3 (fr)
DE (1)	DE19601627A1 (fr)
EE (1)	EE9700020A (fr)
HU (1)	HU9700152D0 (fr)
IL (1)	IL120016A0 (fr)
MA (1)	MA24062A1 (fr)
NO (1)	NO970210L (fr)
PL (1)	PL317985A1 (fr)
SG (1)	SG50001A1 (fr)
SK (1)	SK6997A3 (fr)
TN (1)	TNSN97010A1 (fr)
TR (1)	TR199700039A2 (fr)
ZA (1)	ZA97393B (fr)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7002020B1 (en)	1998-01-23	2006-02-21	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6562844B2 (en)	1998-01-23	2003-05-13	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6239152B1 (en)	1998-01-23	2001-05-29	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
CN1311787A (zh)	1998-06-05	2001-09-05	阿斯特拉曾尼卡有限公司	噁唑烷酮衍生物、其制备方法以及含有它们的药物组合物
WO2001009107A1 (fr)	1999-07-28	2001-02-08	Pharmacia & Upjohn Company	Oxazolidinones et leur utilisation comme anti-infectieux
GB9928568D0 (en)	1999-12-03	2000-02-02	Zeneca Ltd	Chemical compounds
MY127336A (en) *	2000-03-22	2006-11-30	Upjohn Co	Container for linezolid iv solution
US6514529B2 (en)	2000-03-22	2003-02-04	Pharmacia & Upjohn Company	Oxazolidinone tablet formulation
GB0009803D0 (en) *	2000-04-25	2000-06-07	Astrazeneca Ab	Chemical compounds
WO2002002095A2 (fr)	2000-06-30	2002-01-10	Pharmacia & Upjohn Company	Composition et techniques de traitement d'infections bacteriennes
US6423844B1 (en)	2001-06-06	2002-07-23	The United States Of America As Represented By The Secretary Of The Navy	Process for making 1,2,4-triazolo[4,3-a][1,3,5]triazine-3,5,7-triamine
AR038536A1 (es) *	2002-02-25	2005-01-19	Upjohn Co	N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7141588B2 (en) *	2002-02-25	2006-11-28	Pfizer, Inc.	N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
DE60304360T2 (de) *	2002-08-12	2006-11-16	Pharmacia & Upjohn Co. Llc, Kalamazoo	N-aryl-2-oxazolidinone und deren derivate
US7141570B2 (en) *	2002-11-21	2006-11-28	Pharmacia & Upjohn Company	N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
JP2006516989A (ja) *	2003-02-07	2006-07-13	ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー	抗菌剤として使用するための二環式環によりｎ−置換されたオキサゾリジノン誘導体
JP2006516991A (ja) *	2003-02-07	2006-07-13	ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー	抗菌剤
US7012088B2 (en) *	2003-02-24	2006-03-14	Pharmacia & Upjohn Company	Indolone oxazolidinones and derivatives thereof
US20040204463A1 (en) *	2003-04-01	2004-10-14	Harris Christina Renee	N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
US7304050B2 (en) *	2003-09-16	2007-12-04	Pfizer Inc.	Antibacterial agents
WO2005082900A2 (fr) *	2004-01-28	2005-09-09	Pharmacia & Upjohn Company Llc	Amidoxines d'oxazolidinone utilisees en tant qu'agents antibacteriens
BRPI0513083A (pt) *	2004-08-06	2008-04-22	Pharmacia & Upjohn Co Llc	oxazolidinonas contendo oxindóis como agentes antibacterianos
NZ576278A (en) *	2006-10-19	2011-12-22	Signal Pharm Llc	Heteroaryl compounds, compositions thereof, and their use as protein kinase inhibitors
US8110578B2 (en)	2008-10-27	2012-02-07	Signal Pharmaceuticals, Llc	Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway
KR20120091240A (ko)	2009-10-26	2012-08-17	시그날 파마소티칼 엘엘씨	헤테로아릴 화합물의 합성 및 정제 방법
EP3466423B1 (fr)	2011-10-19	2021-07-28	Signal Pharmaceuticals, LLC	Traitement du cancer au moyen d'inhibiteurs de la kinase tor
BR112014013332B1 (pt)	2011-12-02	2022-09-06	Signal Pharmaceuticals, Llc	Composições farmacêuticas de 7-(6-(2-hidroxi-propan-2-il)piridin-3-il)-1-((trans)-4- metoxicicloexil)-3,4-diidropirazino [2,3-b]pirazin-2(1h)-ona, uma forma sólida dessa e métodos de seu uso
KR102064626B1 (ko)	2012-02-24	2020-01-09	시그날 파마소티칼 엘엘씨	Tor 키나제 억제자 복합 치료법을 사용한 비소세포 폐암의 치료 방법
AU2013203714B2 (en)	2012-10-18	2015-12-03	Signal Pharmaceuticals, Llc	Inhibition of phosphorylation of PRAS40, GSK3-beta or P70S6K1 as a marker for TOR kinase inhibitory activity
US9346812B2 (en)	2013-01-16	2016-05-24	Signal Pharmaceuticals, Llc	Substituted pyrrolopyrimidine compounds, compositions thereof, and methods of treatment therewith
MX368286B (es)	2013-04-17	2019-09-27	Signal Pharm Llc	Terapia de combinacion que comprende un inhibidor de tor cinasa y un compuesto de quinazolinona 5-sustituida para tratar cancer.
BR112015026257B1 (pt)	2013-04-17	2022-12-20	Signal Pharmaceuticals, Llc	Uso de um composto dihidropirazino-pirazina e enzalutamida, composição farmacêutica que os compreende, e kit
JP6382945B2 (ja)	2013-04-17	2018-08-29	シグナルファーマシューティカルズ，エルエルシー	ジヒドロピラジノ−ピラジンによる癌治療
HK1221150A1 (zh)	2013-04-17	2017-05-26	西格诺药品有限公司	用二氢吡嗪并-吡嗪类对癌症的治疗
MX393164B (es)	2013-04-17	2025-03-21	Signal Pharm Llc	Formulaciones farmacéuticas, proceso, formas sólidas y métodos de uso relacionados con 1-etil-7-(2-metil-6-(1h-1,2,4-triazol-3-ii)piridin-3-ii)-3,4-dihidropirazino[2,3-b]pirazin-2(1h)-ona.
CN105339008A (zh)	2013-04-17	2016-02-17	西格诺药品有限公司	用于治疗癌症的包括tor激酶抑制剂和n-(3-(5-氟-2-(4-(2-甲氧基乙氧基)苯基氨基)嘧啶-4-基氨基)苯基)丙烯酰胺的组合疗法
EP2986321A1 (fr)	2013-04-17	2016-02-24	Signal Pharmaceuticals, LLC	Polythérapie comprenant un inhibiteur de la kinase tor et un analogue de la cytidine pour le traitement du cancer
NZ629486A (en)	2013-05-29	2017-11-24	Signal Pharm Llc	Pharmaceutical compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino [2,3-b]pyrazin-2(1h)-one, a solid form thereof and methods of their use
US9718824B2 (en)	2014-04-16	2017-08-01	Signal Pharmaceuticals, Llc	Solid forms comprising 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one, and a coformer, compositions and methods of use thereof
NZ714742A (en)	2014-04-16	2017-04-28	Signal Pharm Llc	Solid forms of 1-ethyl-7-(2-methyl-6-(1h-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1h)-one, compositions thereof and methods of their use
EP3131551A4 (fr)	2014-04-16	2017-09-20	Signal Pharmaceuticals, LLC	Formes solides comprenant 1-éthyl-7-(2-méthyl-6-(1h-1,2,4-triazol-3-yl) pyridin-3-yl)-3,4-dihydropyrazino(2,3-b)pyrazin-2(1h)-one, et co-formateur, compositions et procédés d'utilisation de ces dernières
WO2015160868A1 (fr)	2014-04-16	2015-10-22	Signal Pharmaceuticals, Llc	Méthodes de traitement du cancer à l'aide d'une polythérapie avec des inhibiteurs de la kinase tor
NZ629796A (en)	2014-07-14	2015-12-24	Signal Pharm Llc	Amorphous form of 4-((4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7h-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-3-methoxy-n-methylbenzamide, compositions thereof and methods of their use
AU2015289929A1 (en)	2014-07-14	2017-03-02	Signal Pharmaceuticals, Llc	Methods of treating a cancer using substituted pyrrolopyrimidine compounds, compositions thereof
IL271491B2 (en)	2017-06-22	2023-09-01	Celgene Corp	Treatment of carcinoma of the liver characterized by hepatitis b virus infection

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4705799A (en) *	1983-06-07	1987-11-10	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
US4801600A (en) *	1987-10-09	1989-01-31	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4985429A (en) *	1987-10-09	1991-01-15	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4921869A (en) *	1987-10-09	1990-05-01	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4965268A (en) *	1987-10-09	1990-10-23	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4942183A (en) *	1987-10-16	1990-07-17	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
US5254577A (en) *	1988-07-29	1993-10-19	The Du Pont Merck Pharmaceutical Company	Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
WO1990002744A1 (fr)	1988-09-15	1990-03-22	The Upjohn Company	5-beta-amidomethyle-oxazolidine-2-ones a substitution en position 3
US5164510A (en) *	1988-09-15	1992-11-17	The Upjohn Company	5'Indolinyl-5β-amidomethyloxazolidin-2-ones
JP2679745B2 (ja) *	1989-06-29	1997-11-19	明治製菓株式会社	アゾール誘導体及びそれらを有効成分とする抗潰瘍剤
JP2669579B2 (ja) *	1991-10-23	1997-10-29	エーザイ株式会社	オキサゾリドン誘導体
DE4332384A1 (de)	1993-09-23	1995-03-30	Merck Patent Gmbh	Adhäsionsrezeptor-Antagonisten III
TW286317B (fr) *	1993-12-13	1996-09-21	Hoffmann La Roche
DE4425612A1 (de) *	1994-07-20	1996-04-04	Bayer Ag	6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone

1996
- 1996-01-18 DE DE19601627A patent/DE19601627A1/de not_active Withdrawn
1997
- 1997-01-07 EP EP97100114A patent/EP0785201A1/fr not_active Withdrawn
- 1997-01-10 AU AU10123/97A patent/AU1012397A/en not_active Abandoned
- 1997-01-13 US US08/785,145 patent/US5869659A/en not_active Expired - Fee Related
- 1997-01-14 MA MA24463A patent/MA24062A1/fr unknown
- 1997-01-15 TN TNTNSN97010A patent/TNSN97010A1/fr unknown
- 1997-01-15 SG SG1997000082A patent/SG50001A1/en unknown
- 1997-01-15 CA CA002195177A patent/CA2195177A1/fr not_active Abandoned
- 1997-01-16 BG BG101139A patent/BG101139A/xx unknown
- 1997-01-16 JP JP9017765A patent/JPH09202787A/ja active Pending
- 1997-01-16 EE EE9700020A patent/EE9700020A/xx unknown
- 1997-01-16 PL PL97317985A patent/PL317985A1/xx unknown
- 1997-01-16 IL IL12001697A patent/IL120016A0/xx unknown
- 1997-01-17 KR KR1019970001266A patent/KR970059170A/ko not_active Withdrawn
- 1997-01-17 BR BR9700716A patent/BR9700716A/pt unknown
- 1997-01-17 CZ CZ97158A patent/CZ15897A3/cs unknown
- 1997-01-17 HU HU9700152A patent/HU9700152D0/hu unknown
- 1997-01-17 TR TR97/00039A patent/TR199700039A2/xx unknown
- 1997-01-17 ZA ZA97393A patent/ZA97393B/xx unknown
- 1997-01-17 SK SK69-97A patent/SK6997A3/sk unknown
- 1997-01-17 NO NO970210A patent/NO970210L/no unknown

Also Published As

Publication number	Publication date
NO970210D0 (no)	1997-01-17
CZ15897A3 (en)	1997-08-13
EP0785201A1 (fr)	1997-07-23
HU9700152D0 (en)	1997-03-28
SK6997A3 (en)	1997-09-10
BG101139A (en)	1998-04-30
CA2195177A1 (fr)	1997-07-19
MX9700388A (es)	1997-07-31
ZA97393B (en)	1997-07-17
PL317985A1 (en)	1997-07-21
AU1012397A (en)	1997-07-24
US5869659A (en)	1999-02-09
JPH09202787A (ja)	1997-08-05
BR9700716A (pt)	1998-10-06
IL120016A0 (en)	1997-04-15
EE9700020A (et)	1997-08-15
NO970210L (no)	1997-07-21
TR199700039A2 (tr)	1997-08-21
KR970059170A (ko)	1997-08-12
SG50001A1 (en)	1998-06-15
TNSN97010A1 (fr)	2005-03-15
DE19601627A1 (de)	1997-07-24

Publication	Publication Date	Title
MA24062A1 (fr)	1997-10-01	Heteroatome comprenant des cyclopentano-pyridile oxazolidinones
FR2746302B1 (fr)	1998-12-24	Compositions cosmetiques comprenant des nanopigments
DE69721098D1 (de)	2003-05-28	Entwicklungsgerät
DE69720097D1 (de)	2003-04-30	Entwicklungsgerät
NO985294D0 (no)	1998-11-13	Kontrastmidler
DE69715313D1 (de)	2002-10-17	Entwicklungsgerät
ZA986360B (en)	1999-01-27	Tricyclically substituted oxazolidinones
IT1291486B1 (it)	1999-01-11	Corpo portante.
DK0800783T3 (da)	2001-11-05	Gulvrenseapparat
ZA981579B (en)	1999-03-17	Oxazolidinones
NL1001127C1 (nl)	1996-04-09	Bevestigingsinrichting.
FR2718478B1 (fr)	1996-07-05	Plinthe démontable.
DE59710679D1 (de)	2003-10-09	Lüfter
EP0665613A3 (fr)	1997-04-02	Assemblage d'un détecteur démontable.
TR199501336A2 (tr)	1996-06-21	Talim tertibati.
FR2746301B1 (fr)	1998-04-30	Compositions cosmetiques comprenant des nanopigments
FI3488U1 (fi)	1998-07-30	Pitolaite
IT237397Y1 (it)	2000-09-13	Elettrodomestico
EP1008101A4 (fr)	2003-03-26	Support cryptographique
DE59509813D1 (de)	2001-12-13	Substituierte oxazoline
FR2724100B1 (fr)	1997-09-19	Oreiller de soutien.
FR2716348B1 (fr)	1996-05-03	Coiffe réglable.
IT1287807B1 (it)	1998-08-18	Dispositivo di fissaggio di corpo rotante.
FR2721514B1 (fr)	1996-09-06	Compositions thérapeutiques comprenant des 3-phényl-3-hydroxypipéridines.
ITBO940383A0 (it)	1994-08-03	Apparecchio magneto-terapeutico.