MA24261A1 - Pyridines bicycliques condensees. - Google Patents

Pyridines bicycliques condensees.

Info

Publication number
MA24261A1
MA24261A1 MA24705A MA24705A MA24261A1 MA 24261 A1 MA24261 A1 MA 24261A1 MA 24705 A MA24705 A MA 24705A MA 24705 A MA24705 A MA 24705A MA 24261 A1 MA24261 A1 MA 24261A1
Authority
MA
Morocco
Prior art keywords
condensed bicyclic
pyridines
bicyclic pyridines
condensed
bicyclic
Prior art date
Application number
MA24705A
Other languages
English (en)
Inventor
Brandes Arndt
Schmidt Gunter
Angerbauer Rolf
Dieter Bremm Klaus
Schmidt Delf
Schhmacher Joachim
Ligers Michael
Schmeck Carsten
Bischoff Hilmar
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MA24261A1 publication Critical patent/MA24261A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
MA24705A 1996-07-08 1997-07-07 Pyridines bicycliques condensees. MA24261A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19627430A DE19627430A1 (de) 1996-07-08 1996-07-08 Bicyclisch kondensierte Pyridine

Publications (1)

Publication Number Publication Date
MA24261A1 true MA24261A1 (fr) 1998-04-01

Family

ID=7799218

Family Applications (1)

Application Number Title Priority Date Filing Date
MA24705A MA24261A1 (fr) 1996-07-08 1997-07-07 Pyridines bicycliques condensees.

Country Status (30)

Country Link
US (1) US6063788A (fr)
EP (1) EP0825185A1 (fr)
JP (1) JPH1067751A (fr)
KR (1) KR980009247A (fr)
CN (1) CN1172803A (fr)
AR (1) AR007716A1 (fr)
AU (1) AU722365B2 (fr)
BG (1) BG61972B1 (fr)
BR (1) BR9703886A (fr)
CA (1) CA2209609A1 (fr)
CO (1) CO4870759A1 (fr)
CZ (1) CZ214797A3 (fr)
DE (1) DE19627430A1 (fr)
EE (1) EE9700151A (fr)
HN (1) HN1997000082A (fr)
HR (1) HRP970331A2 (fr)
HU (1) HUP9701158A1 (fr)
ID (1) ID17659A (fr)
IL (1) IL121235A0 (fr)
MA (1) MA24261A1 (fr)
NO (1) NO308738B1 (fr)
NZ (1) NZ328260A (fr)
PE (1) PE87798A1 (fr)
PL (1) PL320954A1 (fr)
SG (1) SG46782A1 (fr)
SK (1) SK92697A3 (fr)
TN (1) TNSN97116A1 (fr)
TR (1) TR199700583A2 (fr)
YU (1) YU28897A (fr)
ZA (1) ZA976021B (fr)

Families Citing this family (35)

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Publication number Priority date Publication date Assignee Title
US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
US6262277B1 (en) 1994-09-13 2001-07-17 G.D. Searle And Company Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6268392B1 (en) 1994-09-13 2001-07-31 G. D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
DK1140185T3 (da) 1998-12-23 2003-09-29 Searle Llc Kombinationer af cholesterylestertransferhæmmere og galdesyre kompleksdannende forbindelser til hjertekar indikationer
PT1140190E (pt) 1998-12-23 2003-02-28 Searle Llc Combinacoes de inibidores do transporte ileal dos acidos biliares e agentes sequestrantes dos acidos biliares usadas para problemas cardiovasculares
EP1342475A1 (fr) 1998-12-23 2003-09-10 G.D. Searle LLC. Combinaisons d'inhibiteurs de transport de l'acide biliaire iléal et d'inhibiteurs de la protéine de transfert de l'ester de cholestéryle utilisées dans le cadre de maladies cardio-vasculaires
AU2157400A (en) 1998-12-23 2000-07-31 G.D. Searle & Co. Combinations of cholesteryl ester transfer protein inhibitors and hmg coa reductase inhibitors for cardiovascular indications
EP1140186B1 (fr) 1998-12-23 2003-06-04 G.D. Searle LLC. Combinaisons d'inhibiteurs de la proteine de transfert de l'ester de cholesteryle et de derives de l'acide fibrique utilisees dans le cadre de troubles cardio-vasculaires
MXPA01006472A (es) 1998-12-23 2004-03-10 Searle Llc Combinaciones de inhibidores de transporte de acido biliar ileal y derivados de acido fibrico para indicaciones cardiovasculares.
DK1140184T3 (da) 1998-12-23 2003-09-29 Searle Llc Kombinationer af cholesterylestertransferproteinhæmmere og nikotinsyrederivater til hjertekar indikationer
US6544974B2 (en) 1999-09-23 2003-04-08 G.D. Searle & Co. (R)-chiral halogenated substituted fused heterocyclic amino compounds useful for inhibiting cholesteryl ester transfer protein activity
US20010018446A1 (en) 1999-09-23 2001-08-30 G.D. Searle & Co. Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity
US6924313B1 (en) 1999-09-23 2005-08-02 Pfizer Inc. Substituted tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity
EP1286984A2 (fr) 2000-03-10 2003-03-05 Pharmacia Corporation Procede de preparation de tetrahydrobenzothiepines
US20040219619A1 (en) * 2000-07-21 2004-11-04 Ester Fernandez-Salas Methods of identifying compounds that alter toxin persistence and/or protease activity
US6903109B2 (en) 2001-04-18 2005-06-07 Ortho-Muniel Pharmaceutical, Inc. Arylindenopyridines and related therapeutic and prophylactic methods
US6958328B2 (en) * 2001-04-18 2005-10-25 Ortho-Mcneil Pharmaceutical, Inc Arylindenopyridines and related therapeutic and prophylactic methods
US20050239782A1 (en) * 2001-04-18 2005-10-27 Heintzelman Geoffrey R Arylindenopyridines and related therapeutic and prophylactic methods
MXPA03011784A (es) 2001-06-22 2004-04-02 Pfizer Prod Inc Composiciones farmaceuticas de dispersiones de farmacos y polimeros neutros.
JP4547148B2 (ja) 2001-06-22 2010-09-22 ベンド・リサーチ・インコーポレーテッド 非晶質薬剤の吸着物の医薬組成物
US6740663B2 (en) 2001-11-02 2004-05-25 G.D. Searle, Llc Mono- and di-fluorinated benzothiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (ASBT) and taurocholate uptake
AU2003207431A1 (en) 2002-01-17 2003-09-02 Pharmacia Corporation Novel alkyl/aryl hydroxy or keto thiepines.
WO2003063833A1 (fr) 2002-02-01 2003-08-07 Pfizer Products Inc. Compositions pharmaceutiques de dispersions amorphes de medicaments et materiaux formant des microphases lipophiles
US20040127510A1 (en) * 2002-04-16 2004-07-01 Heintzelman Geoffrey R. Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
MXPA06001417A (es) 2003-08-04 2006-05-15 Pfizer Prod Inc Composiciones farmaceuticas de adsorbatos de farmacos amorfos y materiales que forman microfases lipofilas.
CL2004001884A1 (es) 2003-08-04 2005-06-03 Pfizer Prod Inc Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros.
RU2330682C2 (ru) * 2003-09-26 2008-08-10 Джапан Тобакко Инк. Способ ингибирования продуцирования остаточных липопротеинов
PL1670768T3 (pl) 2003-10-08 2010-01-29 Lilly Co Eli Związki i sposoby leczenia dyslipidemii
EA200601785A1 (ru) 2004-03-26 2007-02-27 Эли Лилли Энд Компани Соединения и способы лечения дислипидемии
BRPI0519602A2 (pt) * 2004-12-18 2009-02-25 Bayer Healthcare Ag derivados de tetrahidroquinolina substituÍdos com 4-cicloalquila e seu uso como medicamento
EP2548894A1 (fr) 2005-02-03 2013-01-23 Bend Research, Inc. Compositions pharmaceutiques à éfficacité améliorée
RU2008119687A (ru) 2005-10-21 2009-11-27 Новартис АГ (CH) Комбинации органических соединений
DE102006012548A1 (de) * 2006-03-18 2007-09-20 Bayer Healthcare Ag Substituierte Chromanol-Derivate und ihre Verwendung
PA8801401A1 (es) * 2007-10-25 2009-05-15 Janssen Pharmaceutica Nv Arilindenopirimidinas y su uso como adenosina a2a
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169857A (en) * 1988-01-20 1992-12-08 Bayer Aktiengesellschaft 7-(polysubstituted pyridyl)-hept-6-endates useful for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis
GB8626344D0 (en) * 1986-11-04 1986-12-03 Zyma Sa Bicyclic compounds
NO177005C (no) * 1988-01-20 1995-07-05 Bayer Ag Analogifremgangsmåte for fremstilling av substituerte pyridiner, samt mellomprodukter til bruk ved fremstillingen
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
ZA911046B (en) * 1990-02-26 1992-10-28 Squibb & Sons Inc Quinoline and pyridine anchors for hmg-coa reductase inhibitors
JPH059179A (ja) * 1990-09-27 1993-01-19 Takeda Chem Ind Ltd 複素環化合物、その製造法及びａｃａｔ阻害剤

Also Published As

Publication number Publication date
KR980009247A (ko) 1998-04-30
NO308738B1 (no) 2000-10-23
AU722365B2 (en) 2000-08-03
NO973144L (no) 1998-01-09
ZA976021B (en) 1998-02-02
CN1172803A (zh) 1998-02-11
BG61972B1 (bg) 1998-11-30
BG101746A (en) 1998-03-31
CZ214797A3 (cs) 1998-01-14
HRP970331A2 (en) 1998-08-31
DE19627430A1 (de) 1998-01-15
PE87798A1 (es) 1999-02-13
TNSN97116A1 (fr) 2005-03-15
AU2844897A (en) 1998-01-15
IL121235A0 (en) 1998-01-04
NZ328260A (en) 1998-09-24
BR9703886A (pt) 1998-11-03
EP0825185A1 (fr) 1998-02-25
SG46782A1 (en) 1998-02-20
CA2209609A1 (fr) 1998-01-08
HU9701158D0 (en) 1997-09-29
TR199700583A2 (xx) 1998-01-21
EE9700151A (et) 1998-02-16
AR007716A1 (es) 1999-11-10
HUP9701158A1 (hu) 1999-09-28
SK92697A3 (en) 1998-02-04
CO4870759A1 (es) 1999-12-27
HN1997000082A (es) 1997-12-26
PL320954A1 (en) 1998-01-19
NO973144D0 (no) 1997-07-07
US6063788A (en) 2000-05-16
JPH1067751A (ja) 1998-03-10
YU28897A (sh) 2000-03-21
ID17659A (id) 1998-01-15

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