MA25009A1 - Procede de preparation de composes derives de la piperidine pour la preparation de compositions antibacteriennes - Google Patents

Procede de preparation de composes derives de la piperidine pour la preparation de compositions antibacteriennes

Info

Publication number
MA25009A1
MA25009A1 MA25816A MA25816A MA25009A1 MA 25009 A1 MA25009 A1 MA 25009A1 MA 25816 A MA25816 A MA 25816A MA 25816 A MA25816 A MA 25816A MA 25009 A1 MA25009 A1 MA 25009A1
Authority
MA
Morocco
Prior art keywords
preparation
piperidine
derived compounds
antibacterial compositions
antibacterial
Prior art date
Application number
MA25816A
Other languages
English (en)
Inventor
Dr David Thomas Davies
Dr Roger Edward Markwell
Dr Neil David Pearson
Dr Andrew Kenneth Takle
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of MA25009A1 publication Critical patent/MA25009A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Quinoline Compounds (AREA)

Abstract

PROCÉDÉ DE PRÉPARATION DE DÉRIVÉS DE LA PIPÉRIDINE ET DE DÉRIVÉS PHARMACEURTIQUES DE CEUX-CI, UTILES DANS LES PROCÉDURES DE TRAITEMENT D'INFECTIONS BACTÉRIENNES CHEZLES MAMMIFÈRES, EN PARTICULIER CHEZ L'HOMME.
MA25816A 1998-10-14 1999-10-12 Procede de preparation de composes derives de la piperidine pour la preparation de compositions antibacteriennes MA25009A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9822440.5A GB9822440D0 (en) 1998-10-14 1998-10-14 Medicaments

Publications (1)

Publication Number Publication Date
MA25009A1 true MA25009A1 (fr) 2000-07-01

Family

ID=10840577

Family Applications (1)

Application Number Title Priority Date Filing Date
MA25816A MA25009A1 (fr) 1998-10-14 1999-10-12 Procede de preparation de composes derives de la piperidine pour la preparation de compositions antibacteriennes

Country Status (11)

Country Link
US (1) US6602882B1 (fr)
EP (1) EP1121355B1 (fr)
JP (1) JP2002527434A (fr)
AT (1) ATE312831T1 (fr)
AU (1) AU6339599A (fr)
DE (1) DE69928952T2 (fr)
ES (1) ES2255306T3 (fr)
GB (1) GB9822440D0 (fr)
MA (1) MA25009A1 (fr)
PE (1) PE20001112A1 (fr)
WO (1) WO2000021952A1 (fr)

Families Citing this family (49)

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SK286420B6 (sk) 1997-09-15 2008-09-05 The Procter & Gamble Company Zlúčenina so štruktúrou chinolónu, farmaceutický prostriedok s jej obsahom a jej použitie
GB9822450D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
GB9914486D0 (en) 1999-06-21 1999-08-18 Smithkline Beecham Plc Medicaments
GB9917406D0 (en) * 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
GB9917408D0 (en) 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
SE9902987D0 (sv) 1999-08-24 1999-08-24 Astra Pharma Prod Novel compounds
US6803369B1 (en) 2000-07-25 2004-10-12 Smithkline Beecham Corporation Compounds and methods for the treatment of neoplastic disease
EP1305308B1 (fr) 2000-07-26 2006-12-20 Smithkline Beecham Plc Aminopiperidine quinolines et leurs analogues azaisosteres presentant une activite antibacterienne
WO2002024684A1 (fr) * 2000-09-21 2002-03-28 Smithkline Beecham P.L.C. Derives de quinoline en tant qu'agents antibacteriens
GB0031086D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0031088D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) * 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0104050D0 (en) 2001-02-19 2001-04-04 Astrazeneca Ab Chemical compounds
GB0107228D0 (en) 2001-03-22 2001-05-16 Astrazeneca Ab Chemical compounds
GB0112836D0 (en) * 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112834D0 (en) * 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0118238D0 (en) * 2001-07-26 2001-09-19 Smithkline Beecham Plc Medicaments
EP1450802A2 (fr) * 2001-10-30 2004-09-01 The General Hospital Corporation Methodes de prevention ou de traitement d'infections bacteriennes ou mycosiques
SE0103818D0 (sv) 2001-11-15 2001-11-15 Astrazeneca Ab Chemical compounds
EP1470131A2 (fr) * 2002-01-29 2004-10-27 Glaxo Group Limited Composes aminopiperidine, leur procede de preparation et compositions pharmaceutiques les contenant
US7312212B2 (en) * 2002-01-29 2007-12-25 Glaxo Group Limited Aminopiperidine derivatives
TW200406413A (en) * 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
AR040336A1 (es) * 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
US6900224B2 (en) 2002-07-31 2005-05-31 The Procter & Gamble Company Antimicrobial quinolones, their compositions and uses
EP1560488B1 (fr) 2002-11-05 2010-09-01 Glaxo Group Limited Agents antibacteriens
US7232832B2 (en) 2002-11-05 2007-06-19 Smithkline Beecham Corporation Antibacterial agents
WO2004050036A2 (fr) 2002-12-04 2004-06-17 Glaxo Group Limited Quinoleines et derives nitrogenes de ces composes ainsi que leur utilisation en tant qu'agents antibacteriens
AR042486A1 (es) * 2002-12-18 2005-06-22 Glaxo Group Ltd Compuesto de quinolina y naftiridina halosustituido en la posicion 3, procedimiento para preparar el compuesto, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion .
ATE440835T1 (de) * 2003-03-06 2009-09-15 Glaxo Group Ltd Heterozyklische harnstoff-derivate für die behandlung von schmerzen.
EP1601665A2 (fr) * 2003-03-07 2005-12-07 Glaxo Group Limited Derives d'uree
GB0305426D0 (en) * 2003-03-08 2003-04-16 Glaxo Group Ltd Novel compounds
SE0301369D0 (sv) 2003-05-09 2003-05-09 Astrazeneca Ab Chemical compounds
FR2867472B1 (fr) * 2004-03-12 2008-07-18 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
JP2008505920A (ja) * 2004-07-08 2008-02-28 グラクソ　グループ　リミテッド 抗菌剤
JP2008528586A (ja) * 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
US7511035B2 (en) 2005-01-25 2009-03-31 Glaxo Group Limited Antibacterial agents
JP2008528598A (ja) * 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
WO2006081182A2 (fr) * 2005-01-25 2006-08-03 Glaxo Group Limited Agents antibacteriens
EP1845995A4 (fr) * 2005-01-25 2010-03-03 Glaxo Group Ltd Agents antibacteriens
JP5023054B2 (ja) 2005-03-31 2012-09-12 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 抗バクテリア剤としての二環式ピラゾール化合物
MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
ATE536351T1 (de) 2006-01-26 2011-12-15 Actelion Pharmaceuticals Ltd Tetrahydropyran-antibiotika
MX2008012488A (es) 2006-03-28 2008-10-10 Procter & Gamble Un proceso de acoplamiento para preparar intermedios de quinolona.
EP2001862B1 (fr) 2006-03-28 2011-04-27 Warner Chilcott Company, LLC Malates et formes polymorphes de l'acide (3s,5s)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinoleine-carboxylique
CN101679357A (zh) * 2007-05-09 2010-03-24 辉瑞大药厂 取代的杂环衍生物及其组合物和作为抗菌剂的药物用途
EP2332939A1 (fr) 2009-11-26 2011-06-15 Æterna Zentaris GmbH Nouveaux dérivés de naphtyridine et l'utilisation associée en tant qu'inhibiteurs de kinase
WO2020169593A1 (fr) 2019-02-19 2020-08-27 Univerza V Ljubljani Antibactériens à base de fragments monocycliques couplés à un échafaudage de naphtyridine aminopipéridine
KR20220087497A (ko) 2019-10-18 2022-06-24 더 리전츠 오브 더 유니버시티 오브 캘리포니아 병원성 혈관을 표적화하기 위한 화합물 및 방법
US12590298B2 (en) 2019-10-18 2026-03-31 The Regents Of The University Of California Ex vivo tumor angiogenesis model

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JPS4418299Y1 (fr) 1965-01-16 1969-08-07
US4472404A (en) 1982-08-16 1984-09-18 The Dow Chemical Company 8-Quinolinyl carbamates and their use as urinary tract antimicrobials
EP0387510A1 (fr) * 1989-02-10 1990-09-19 Bayer Ag Dérivés de 8-carbamoyloxy-quinoléine, procédé pour leur préparation et leur utilisation comme pesticides
JPH0495071A (ja) * 1990-08-10 1992-03-27 Kyorin Pharmaceut Co Ltd カルバミン酸誘導体
JP3169188B2 (ja) * 1991-01-31 2001-05-21 杏林製薬株式会社 カルバミン酸誘導体及びその製造方法
WO1994014801A1 (fr) 1992-12-29 1994-07-07 Smithkline Beecham Plc Derives heterocycliques de l'uree antagonistes de 5ht2c et 5h¿2b?
WO1996023782A1 (fr) * 1995-02-02 1996-08-08 Daiichi Pharmaceutical Co., Ltd. Composes heterocycliques
JPH11514361A (ja) 1995-10-16 1999-12-07 藤沢薬品工業株式会社 Ｈ＋−ＡＴＰａｓｅとしての複素環式化合物
JP3933244B2 (ja) 1997-04-04 2007-06-20 株式会社資生堂 アルキレンジアミン誘導体及び抗潰瘍剤、抗菌剤
CA2318842A1 (fr) 1998-01-26 1999-07-29 Julie Dorothy Warrack Derives de quinoline utilises comme antibacteriens
FR2798656B1 (fr) 1999-09-17 2004-12-17 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent

Also Published As

Publication number Publication date
DE69928952D1 (de) 2006-01-19
EP1121355A1 (fr) 2001-08-08
DE69928952T2 (de) 2007-01-11
PE20001112A1 (es) 2000-10-14
US6602882B1 (en) 2003-08-05
GB9822440D0 (en) 1998-12-09
ATE312831T1 (de) 2005-12-15
WO2000021952A1 (fr) 2000-04-20
ES2255306T3 (es) 2006-06-16
JP2002527434A (ja) 2002-08-27
EP1121355B1 (fr) 2005-12-14
AU6339599A (en) 2000-05-01

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