MA26057A1 - Appareil et procédé de perçage de peau par microdents - Google Patents

Appareil et procédé de perçage de peau par microdents

Info

Publication number
MA26057A1
MA26057A1 MA27151A MA27151A MA26057A1 MA 26057 A1 MA26057 A1 MA 26057A1 MA 27151 A MA27151 A MA 27151A MA 27151 A MA27151 A MA 27151A MA 26057 A1 MA26057 A1 MA 26057A1
Authority
MA
Morocco
Prior art keywords
impact
microprotrusion member
stratum corneum
skin
microdents
Prior art date
Application number
MA27151A
Other languages
English (en)
Inventor
Michel J N Cormier
Peter E Daddona
Richard L Keenan
Weiqi Lin
James A Matriano
Ahmad P Samiee
Joseph C Trautman
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22906027&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA26057(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alza Corp filed Critical Alza Corp
Publication of MA26057A1 publication Critical patent/MA26057A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/20Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/20Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205Vaccinating by means of needles or other puncturing devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/150022Source of blood for capillary blood or interstitial fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150274Manufacture or production processes or steps for blood sampling devices
    • A61B5/150282Manufacture or production processes or steps for blood sampling devices for piercing elements, e.g. blade, lancet, canula, needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150801Means for facilitating use, e.g. by people with impaired vision; means for indicating when used correctly or incorrectly; means for alarming
    • A61B5/150824Means for facilitating use, e.g. by people with impaired vision; means for indicating when used correctly or incorrectly; means for alarming by visual feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150977Arrays of piercing elements for simultaneous piercing
    • A61B5/150984Microneedles or microblades
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101Details
    • A61B5/15103Piercing procedure
    • A61B5/15107Piercing being assisted by a triggering mechanism
    • A61B5/15113Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101Details
    • A61B5/15115Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
    • A61B5/15117Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15142Devices intended for single use, i.e. disposable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15186Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
    • A61B5/15188Constructional features of reusable driving devices
    • A61B5/1519Constructional features of reusable driving devices comprising driving means, e.g. a spring, for propelling the piercing unit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00747Dermatology
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Manufacturing & Machinery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Optics & Photonics (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)
  • Perforating, Stamping-Out Or Severing By Means Other Than Cutting (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Massaging Devices (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
MA27151A 2000-10-13 2003-05-12 Appareil et procédé de perçage de peau par microdents MA26057A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24030700P 2000-10-13 2000-10-13

Publications (1)

Publication Number Publication Date
MA26057A1 true MA26057A1 (fr) 2004-04-01

Family

ID=22906027

Family Applications (1)

Application Number Title Priority Date Filing Date
MA27151A MA26057A1 (fr) 2000-10-13 2003-05-12 Appareil et procédé de perçage de peau par microdents

Country Status (22)

Country Link
US (2) US7131960B2 (fr)
EP (1) EP1341453B1 (fr)
JP (1) JP4659332B2 (fr)
KR (1) KR20030068136A (fr)
CN (1) CN1250171C (fr)
AT (1) ATE428357T1 (fr)
AU (2) AU9682801A (fr)
BR (1) BR0114629A (fr)
CA (1) CA2425315C (fr)
CZ (1) CZ20031037A3 (fr)
DE (1) DE60138411D1 (fr)
ES (1) ES2324461T3 (fr)
HU (1) HUP0303558A2 (fr)
IL (1) IL155374A0 (fr)
MA (1) MA26057A1 (fr)
MX (1) MXPA03003299A (fr)
NO (1) NO20031681L (fr)
NZ (1) NZ525294A (fr)
PL (1) PL360998A1 (fr)
RU (1) RU2275871C2 (fr)
WO (1) WO2002030301A1 (fr)
ZA (1) ZA200303633B (fr)

Families Citing this family (143)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0914178B1 (fr) * 1996-06-18 2003-03-12 Alza Corporation Dispositif d'amelioration d'apport ou d'echantillonnage d'agents transdermiques
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
CA2425312C (fr) * 2000-10-13 2010-02-16 Alza Corporation Logement pour element a microprotrusions pour applicateur a percussion
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
PL360998A1 (en) * 2000-10-13 2004-09-20 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
BR0114909A (pt) 2000-10-26 2004-02-03 Alza Corp Dispositivos de distribuição de drogas transdérmicas possuindo microprotuberâncias revestidas
US6855372B2 (en) * 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
NZ529029A (en) * 2001-04-20 2005-07-29 Alza Corp Microprojection array having a beneficial agent containing coating
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
AU2002352978A1 (en) * 2001-11-30 2003-06-17 Alza Corporation Methods and apparatuses for forming microprojection arrays
AU2002357372B2 (en) * 2001-12-20 2008-11-20 Alza Corporation Skin-piercing microprojections having piercing depth control
US6912417B1 (en) 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
WO2004002566A1 (fr) * 2002-06-28 2004-01-08 Alza Corporation Dispositifs d'administration de medicament transdermique ayant des microprotuberances enduites
KR20120087197A (ko) * 2002-07-19 2012-08-06 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로 니들 장치, 마이크로 니들 장치를 사용하는 방법 및 마이크로 니들 장치를 송출하는 방법
US20040115167A1 (en) * 2002-09-30 2004-06-17 Michel Cormier Drug delivery device and method having coated microprojections incorporating vasoconstrictors
WO2004044557A2 (fr) * 2002-11-12 2004-05-27 Argose, Inc. Mesure non invasive d'analytes
US20040106163A1 (en) * 2002-11-12 2004-06-03 Workman Jerome James Non-invasive measurement of analytes
AR042815A1 (es) * 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
US7087063B2 (en) * 2003-02-19 2006-08-08 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Abrasion device and method
US7226457B2 (en) * 2003-02-19 2007-06-05 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Epidermal sampling apparatus and method
MXPA06000281A (es) * 2003-06-30 2006-07-03 Johnson & Johnson Formulaciones para microproyecciones revestidas que contienen contraiones no volatiles.
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
EP1643918A1 (fr) * 2003-07-02 2006-04-12 Alza Corporation Timbre transdermique et methode d'immunisation mettant en oeuvre un reseau de microprojections
BRPI0413360A (pt) * 2003-08-04 2006-10-10 Alza Corp método e dispositivo para aumentar o fluxo de agentes transdérmicos
EP1675539A4 (fr) 2003-10-24 2007-09-12 Alza Corp Procede et systeme de pretraitement permettant d'ameliorer l'administration transdermique de medicaments
CN1897899A (zh) * 2003-10-24 2007-01-17 阿尔扎公司 促进透皮药物传递的装置和方法
US7455654B2 (en) * 2003-10-28 2008-11-25 Alza Corporation Method and apparatus for reducing the incidence of tobacco use
KR20070001886A (ko) * 2003-10-28 2007-01-04 알자 코포레이션 치료용 펩타이드 및 단백질의 폴리머 컨쥬게이트의 피복된미세돌출부를 통한 전달
CA2543641A1 (fr) 2003-10-31 2005-05-19 Alza Corporation Applicateur a actionnement automatique pour reseau de micro-protuberances
WO2005065241A2 (fr) * 2003-12-24 2005-07-21 Argose, Inc. Rapporteurs de metabolites a petites molecules destines a etre utilises comme biocapteurs de glucose in vivo
US20070083151A1 (en) * 2003-12-29 2007-04-12 Carter Chad J Medical devices and kits including same
CN1636505B (zh) * 2004-01-09 2011-11-09 希森美康株式会社 提取器具、提取装置和血糖值测量装置
CA2559083C (fr) 2004-03-08 2015-06-16 Ichor Medical Systems, Inc. Appareil ameliore pour une administration electriquement mediee d'agents therapeutiques
CA2560840C (fr) 2004-03-24 2014-05-06 Corium International, Inc. Dispositif d'administration transdermique
CA2562642A1 (fr) * 2004-04-13 2005-11-03 Alza Corporation Appareil et procede d'administration transdermique de multiples vaccins
MXPA06013168A (es) 2004-05-13 2007-05-15 Johnson & Johnson Aparato y metodo para el suministro transdermico de agentes de la hormona paratiroidea.
US20060030811A1 (en) * 2004-08-03 2006-02-09 Wong Patrick S Method and device for enhancing transdermal agent flux
KR20070099540A (ko) * 2004-09-08 2007-10-09 알자 코포레이션 향상된 피부 점착성 및 순응도를 갖는 미세돌출부 어레이
AU2005306429B2 (en) 2004-11-18 2011-04-14 3M Innovative Properties Company Microneedle array applicator and retainer
KR20130026511A (ko) 2004-11-18 2013-03-13 쓰리엠 이노베이티브 프로퍼티즈 컴파니 로우-프로파일 미세 바늘 어레이 인가 장치
JP2008530230A (ja) * 2005-02-16 2008-08-07 アルザ・コーポレーシヨン エリスロポエチンに基づく剤の経皮送達のための装置および方法
WO2006105146A2 (fr) 2005-03-29 2006-10-05 Arkal Medical, Inc. Dispositifs, systemes, procedes et outils pour la surveillance continue du glucose
EP1871459B1 (fr) 2005-04-07 2019-06-19 3M Innovative Properties Company Systeme de captage de retroaction d'un outil
CN101189030A (zh) * 2005-06-02 2008-05-28 阿尔扎公司 透皮递送器械的最终消毒方法
US20080195035A1 (en) * 2005-06-24 2008-08-14 Frederickson Franklyn L Collapsible Patch and Method of Application
WO2007002521A2 (fr) * 2005-06-27 2007-01-04 3M Innovative Properties Company Dispositif applicateur de matrice de micro-aiguilles et procede d'application d'une telle matrice
US20070078414A1 (en) * 2005-08-05 2007-04-05 Mcallister Devin V Methods and devices for delivering agents across biological barriers
CA2619452A1 (fr) * 2005-09-12 2007-03-22 Alza Corporation Dispositif d'administration transdermique enduisable a microprojections
WO2007064486A1 (fr) * 2005-11-30 2007-06-07 3M Innovative Properties Company Reseaux de microaiguilles et leurs methodes d'utilisation
JP4963849B2 (ja) 2006-03-13 2012-06-27 シスメックス株式会社 微細孔形成システム
AU2007225056A1 (en) * 2006-03-15 2007-09-20 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents to prevent or treat osteopenia
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
US20070299388A1 (en) * 2006-04-25 2007-12-27 Alza Corporation Microprojection array application with multilayered microprojection member for high drug loading
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
US20080058726A1 (en) * 2006-08-30 2008-03-06 Arvind Jina Methods and Apparatus Incorporating a Surface Penetration Device
AU2008209537B2 (en) 2007-01-22 2013-01-31 Corium Pharma Solutions, Inc. Applicators for microneedle arrays
AU2008241470B2 (en) 2007-04-16 2013-11-07 Corium Pharma Solutions, Inc. Solvent-cast microneedle arrays containing active
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
US20090247984A1 (en) * 2007-10-24 2009-10-01 Masimo Laboratories, Inc. Use of microneedles for small molecule metabolite reporter delivery
CA2704164A1 (fr) * 2007-10-29 2009-05-07 Transpharma Medical Ltd. Sechage vertical de timbres transdermiques
WO2009129349A2 (fr) * 2008-04-16 2009-10-22 Kim Stanley I Dispositif auto-piqueur jetable à usage unique et procédés
JP2012509106A (ja) * 2008-11-18 2012-04-19 スリーエム イノベイティブ プロパティズ カンパニー 中空のマイクロニードルアレイ及び方法
WO2012018486A2 (fr) 2010-07-26 2012-02-09 Seventh Sense Biosystems, Inc. Distribution et/ou réception rapide de fluides
US9295417B2 (en) 2011-04-29 2016-03-29 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
CN102405018B (zh) 2009-03-02 2014-11-19 第七感生物系统有限公司 与血液取样相关联的技术和装置
CA2769102C (fr) 2009-07-31 2017-09-19 3M Innovative Properties Company Matrices de micro-aiguilles creuses
US8088108B2 (en) * 2009-08-22 2012-01-03 Joseph Wayne Kraft Rapid local anesthesia injection cone
US8409147B2 (en) * 2009-08-22 2013-04-02 Joseph Wayne Kraft Rapid local anesthesia linear injection device
US8911422B2 (en) 2010-02-24 2014-12-16 Hisamitsu Pharmaceutical Co., Inc. Micro-needle device
JP5860033B2 (ja) * 2010-04-28 2016-02-16 キンバリー クラーク ワールドワイド インコーポレイテッド siRNA送達用の医療デバイス
CA2797204C (fr) * 2010-04-28 2018-06-12 Kimberly-Clark Worldwide, Inc. Dispositif pour administrer un medicament contre l'arthrite rhumatoide
GB201007207D0 (en) 2010-04-29 2010-06-16 Univ Cork Method
WO2011140274A2 (fr) * 2010-05-04 2011-11-10 Corium International, Inc. Méthode et dispositif permettant l'administration transdermique d'hormone parathyroïdienne au moyen d'un réseau de microprojections
EP2566568B1 (fr) 2010-05-04 2019-04-10 Corium International, Inc. Applicateurs pour micro-aiguilles
WO2011148995A1 (fr) 2010-05-28 2011-12-01 久光製薬株式会社 Réseau à fines protubérances
CN102917751A (zh) 2010-05-28 2013-02-06 久光制药株式会社 具有带有微小突起的阵列的装置
JP5562138B2 (ja) 2010-06-24 2014-07-30 シスメックス株式会社 微細孔形成装置
EP2399635A1 (fr) 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injecteur
US8257379B2 (en) * 2010-07-29 2012-09-04 Kyphon Sarl Tissue structure perforation system and method
WO2012021801A2 (fr) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systèmes et procédés adaptés pour surveiller des sujets
US20130226098A1 (en) * 2010-10-07 2013-08-29 Hisamitsu Pharmaceutical Co., Inc. Applicator
EP2992827B1 (fr) 2010-11-09 2017-04-19 Seventh Sense Biosystems, Inc. Systèmes et interfaces pour prélèvement de sang
DE202010013095U1 (de) 2010-12-10 2011-02-17 Mt Derm Gmbh Vorrichtung zum wiederholten Aufstechen von Haut und Stechmodul
EP2489387A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489380A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Dispositif d'injection
EP2489385A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
UA112769C2 (uk) 2011-02-18 2016-10-25 Ендо Фармасьютікалз Інк. Аміноінданові сполуки і їх застосування при лікуванні болю
EP2489381A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489382A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489384A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489386A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489390A1 (fr) * 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Mécanisme d'encliquetage
EP2489388A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489389A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Mécanisme d'encliquetage
KR20120119250A (ko) * 2011-04-21 2012-10-31 (주)마이티시스템 단턱이 형성된 미세바늘
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
CN103874460B (zh) * 2011-04-29 2016-06-22 第七感生物系统有限公司 一种用于从受验者的皮肤接收血液或其它物质的装置
KR20140034200A (ko) 2011-04-29 2014-03-19 세븐쓰 센스 바이오시스템즈, 인크. 혈액 스폿들 또는 다른 신체 유체들을 수집 및/또는 조작하기 위한 시스템들 및 방법들
USD687551S1 (en) * 2011-06-09 2013-08-06 3M Innovative Properties Company Micro-needle applicator device
USD687550S1 (en) * 2011-06-09 2013-08-06 3M Innovative Properties Company Handle for a micro-needle device
US9498611B2 (en) 2011-10-06 2016-11-22 Hisamitsu Pharmaceutical Co., Inc. Applicator
CN103874518A (zh) 2011-10-12 2014-06-18 3M创新有限公司 一体化微针阵列递送系统
HUE032240T2 (en) 2011-10-24 2017-09-28 Asana Biosciences Llc cyclohexylamines
USD733290S1 (en) 2012-01-27 2015-06-30 3M Innovative Properties Company Microneedle applicator
US20150057604A1 (en) 2012-04-05 2015-02-26 Hisamitsu Pharmaceutical Co., Inc. Puncture Device and Method for Manufacturing Same
EP4112112A1 (fr) * 2012-05-01 2023-01-04 University of Pittsburgh - Of the Commonwealth System of Higher Education Réseaux de micro-aiguilles à extrémité chargée pour l'insertion transdermique
JP6009302B2 (ja) * 2012-09-27 2016-10-19 シスメックス株式会社 微細孔形成装置、微細針チップおよびチップホルダ
US10548854B2 (en) 2012-10-01 2020-02-04 The Hong Kong University Of Science And Technology Manufacture of nonelectronic, active-infusion patch and device for transdermal delivery across skin
USD725262S1 (en) 2012-11-16 2015-03-24 Ndm Technologies Limited Microneedle applicator
JP6865524B2 (ja) 2012-12-21 2021-04-28 コリウム, インコーポレイテッド 治療剤を送達するためのマイクロアレイおよび使用方法
US9913970B2 (en) 2012-12-21 2018-03-13 Hisamitsu Pharmaceutical Co., Ltd. Applicator
US20150352295A1 (en) * 2013-01-08 2015-12-10 3M Innovative Properties Company Application For Applying A Microneedle Device To Skin
CA3130120A1 (fr) 2013-03-12 2014-10-09 Corium, Inc. Applicateurs de microprojection
WO2014144973A1 (fr) 2013-03-15 2014-09-18 Corium International, Inc. Micro-réseau pour administrer un agent thérapeutique, procédés d'utilisation et procédés de fabrication
US10384045B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
JP6689187B2 (ja) 2013-03-15 2020-04-28 コリウム, インコーポレイテッド 複数の衝突微小突起アプリケータおよび使用方法
RU2711567C2 (ru) 2013-03-15 2020-01-17 Кориум, ИНК. Микрочип для доставки лекарственного средства и способы его использования
EP3027263A1 (fr) 2013-07-30 2016-06-08 ZP Opco, Inc. Applicateur extra-plat de tampon de micro-aiguilles
WO2015040697A1 (fr) 2013-09-18 2015-03-26 コスメディ製薬株式会社 Dispositif d'application de timbre de micro-aiguille et organe de retenue de timbre
EP3067088B1 (fr) 2013-11-05 2019-09-04 Hisamitsu Pharmaceutical Co., Inc. Applicateur
JP6616772B2 (ja) 2013-12-16 2019-12-04 アサナ・バイオサイエンシズ,リミテッド・ライアビリティ・カンパニー P2x3および/またはp2x2/3化合物ならびに方法
CN103654969B (zh) * 2013-12-24 2015-12-30 湖州美奇医疗器械有限公司 一种医疗助针器
EP3188714A1 (fr) 2014-09-04 2017-07-12 Corium International, Inc. Matrice de microstructures, procédé de production et procédés d'utilisation
US10137289B2 (en) * 2014-12-20 2018-11-27 Esthetic Education LLC Microneedle cartridge and nosecone assembly
WO2016149673A1 (fr) 2015-03-18 2016-09-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Composés bioactifs conjugués à des substrats de réseaux de micro-aiguilles
MA41818A (fr) 2015-03-27 2018-01-30 Leo Pharma As Timbre à micro-aiguilles pour administration d'un principe actif à la peau
WO2017004067A1 (fr) 2015-06-29 2017-01-05 Corium International, Inc. Micro-réseau pour l'administration d'un agent thérapeutique, procédés d'utilisation, et procédés de fabrication
JP2017023404A (ja) 2015-07-22 2017-02-02 日本写真印刷株式会社 マイクロニードルパッチ用インパクト付加型アプリケータ及び先端部材
WO2017038499A1 (fr) 2015-09-02 2017-03-09 久光製薬株式会社 Applicateur
US9918932B2 (en) 2016-02-19 2018-03-20 Zosano Pharma Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines
WO2017159779A1 (fr) 2016-03-16 2017-09-21 コスメディ製薬株式会社 Boîtier de timbre à micro-aiguilles
EP3436139B1 (fr) 2016-03-28 2025-04-30 PapiVax Biotech, Inc. Procédé et appareil permettant d'administrer des agents thérapeutiques
CN109996546B (zh) 2016-09-30 2023-06-27 阿沙纳生物科学公司 P2x3和/或p2x2/3化合物及方法
JP6931217B2 (ja) 2017-03-28 2021-09-01 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ
US11660264B2 (en) 2017-08-23 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
WO2019040063A1 (fr) 2017-08-23 2019-02-28 Zp Opco, Inc. Procédé d'obtention rapide de concentrations thérapeutiques de zolmitriptan pour le traitement de migraines et de céphalées de horton
BR112020007566A2 (pt) 2017-10-17 2020-09-24 3M Innovative Properties Company aplicador para aplicar uma matriz de microagulhas à pele
CN111629772A (zh) 2018-01-24 2020-09-04 考司美德制药株式会社 微针用张紧器具
US11660265B2 (en) 2018-06-28 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
DE102019200563A1 (de) * 2019-01-17 2020-07-23 Lts Lohmann Therapie-Systeme Ag Applikator
JP7491551B2 (ja) 2019-04-25 2024-05-28 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ2
US20220249822A1 (en) * 2021-02-11 2022-08-11 Tokitae, LLC Applicator for Intradermal Microneedle Patches

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25637E (en) 1964-09-08 Means for vaccinating
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) 1972-02-14 1973-08-13 Ici Ltd Pansements
GB2064329B (en) * 1979-11-01 1983-06-22 Matburn Holdings Ltd Multiple puncture apparatus
US4553541A (en) * 1981-03-23 1985-11-19 Becton, Dickinson And Co. Automatic retractable lancet assembly
EP0429842B1 (fr) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Dispositif d'administration transcutanée de médicaments à base de protéine ou de peptide
US5279544A (en) * 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US6048337A (en) 1992-01-07 2000-04-11 Principal Ab Transdermal perfusion of fluids
CN1098712C (zh) 1994-08-18 2003-01-15 Nmt集团公开有限公司 针缩回机构
JPH10510175A (ja) * 1994-12-09 1998-10-06 ノバルティス アクチェンゲゼルシャフト 経皮システム
WO1996037256A1 (fr) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Timbre micromecanique pour ameliorer l'administration de composes a travers la peau
WO1996037155A1 (fr) * 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Dispositif micromecanique et procede pour ameliorer l'administration percutanee de composes
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
US5613978A (en) 1996-06-04 1997-03-25 Palco Laboratories Adjustable tip for lancet device
EP0914178B1 (fr) * 1996-06-18 2003-03-12 Alza Corporation Dispositif d'amelioration d'apport ou d'echantillonnage d'agents transdermiques
CA2259437C (fr) 1996-07-03 2006-12-05 Altea Technologies, Inc. Microporation mecanique multiple de la peau ou de la muqueuse
ATE231015T1 (de) 1996-09-17 2003-02-15 Deka Products Lp System zur medikamentenabgabe durch transport
AU722574B2 (en) * 1996-12-20 2000-08-10 Alza Corporation Device and method for enhancing transdermal agent flux
DE19654391A1 (de) 1996-12-27 1998-07-02 Basf Ag Katalysator zur selektiven Herstellung von Propylen aus Propan
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
DE69839969D1 (de) * 1997-12-11 2008-10-16 Alza Corp Vorrichtung zur verbesserung des transdermalen flusses von medikamenten
CA2313698C (fr) * 1997-12-11 2008-04-15 Alza Corporation Dispositif renforcant le flux d'agents transdermiques
JP4061022B2 (ja) 1997-12-11 2008-03-12 アルザ・コーポレーション 経皮輸送剤の流量促進装置
WO1999064580A1 (fr) 1998-06-10 1999-12-16 Georgia Tech Research Corporation Dispositifs a microaiguilles et procedes de fabrication et d'utilisation correspondants
GB9817662D0 (en) * 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
ATE324922T1 (de) * 1999-06-08 2006-06-15 Altea Therapeutics Corp Vorrichtung zur mikroporation eines biologischen gewebes mittels einer filmgewebe schnittstellenvorrichtung und verfahren
US6364889B1 (en) * 1999-11-17 2002-04-02 Bayer Corporation Electronic lancing device
WO2001043643A1 (fr) 1999-12-16 2001-06-21 Alza Corporation Dispositif destine a augmenter le flux transdermique de substances echantillonnees
PL360978A1 (en) * 2000-10-13 2004-09-20 Alza Corporation Microblade array impact applicator
CA2425312C (fr) * 2000-10-13 2010-02-16 Alza Corporation Logement pour element a microprotrusions pour applicateur a percussion
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
PL360998A1 (en) * 2000-10-13 2004-09-20 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US7108681B2 (en) * 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
BR0114909A (pt) * 2000-10-26 2004-02-03 Alza Corp Dispositivos de distribuição de drogas transdérmicas possuindo microprotuberâncias revestidas
US6855372B2 (en) * 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
NZ529029A (en) * 2001-04-20 2005-07-29 Alza Corp Microprojection array having a beneficial agent containing coating
US6591124B2 (en) * 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
US6767341B2 (en) * 2001-06-13 2004-07-27 Abbott Laboratories Microneedles for minimally invasive drug delivery
AU2002352978A1 (en) * 2001-11-30 2003-06-17 Alza Corporation Methods and apparatuses for forming microprojection arrays
AU2002357372B2 (en) * 2001-12-20 2008-11-20 Alza Corporation Skin-piercing microprojections having piercing depth control
WO2004002566A1 (fr) * 2002-06-28 2004-01-08 Alza Corporation Dispositifs d'administration de medicament transdermique ayant des microprotuberances enduites
AR042815A1 (es) * 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
MXPA06000281A (es) * 2003-06-30 2006-07-03 Johnson & Johnson Formulaciones para microproyecciones revestidas que contienen contraiones no volatiles.
KR20070001886A (ko) * 2003-10-28 2007-01-04 알자 코포레이션 치료용 펩타이드 및 단백질의 폴리머 컨쥬게이트의 피복된미세돌출부를 통한 전달
CA2543641A1 (fr) * 2003-10-31 2005-05-19 Alza Corporation Applicateur a actionnement automatique pour reseau de micro-protuberances
BRPI0416042A (pt) * 2003-11-13 2007-01-02 Alza Corp composição e aparelho para suprimento transdérmico
MXPA06013168A (es) * 2004-05-13 2007-05-15 Johnson & Johnson Aparato y metodo para el suministro transdermico de agentes de la hormona paratiroidea.

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IL155374A0 (en) 2003-11-23
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US7798987B2 (en) 2010-09-21
CA2425315A1 (fr) 2002-04-18
HUP0303558A2 (en) 2004-01-28
CA2425315C (fr) 2010-01-12
PL360998A1 (en) 2004-09-20
US20050234401A1 (en) 2005-10-20
US7131960B2 (en) 2006-11-07
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NO20031681D0 (no) 2003-04-11
ATE428357T1 (de) 2009-05-15
EP1341453B1 (fr) 2009-04-15
DE60138411D1 (de) 2009-05-28
ES2324461T3 (es) 2009-08-07
CN1479590A (zh) 2004-03-03
EP1341453A1 (fr) 2003-09-10
AU2001296828B2 (en) 2005-11-24
CN1250171C (zh) 2006-04-12
BR0114629A (pt) 2004-01-20
JP2004510535A (ja) 2004-04-08
KR20030068136A (ko) 2003-08-19
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NO20031681L (no) 2003-06-13
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US20020123675A1 (en) 2002-09-05
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