MA26554A1 - Derives d-homo-9, 10-secocholesta-23-yne-3,25-diol - Google Patents

Derives d-homo-9, 10-secocholesta-23-yne-3,25-diol

Info

Publication number
MA26554A1
MA26554A1 MA25300A MA25300A MA26554A1 MA 26554 A1 MA26554 A1 MA 26554A1 MA 25300 A MA25300 A MA 25300A MA 25300 A MA25300 A MA 25300A MA 26554 A1 MA26554 A1 MA 26554A1
Authority
MA
Morocco
Prior art keywords
secocholesta
yne
homo
diol
derivatives
Prior art date
Application number
MA25300A
Other languages
English (en)
Inventor
Bauer Franz
Mohr Peter
Muller Marc
Pirson Wolfgang
Barbier Pierre
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA26554A1 publication Critical patent/MA26554A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • C07C35/36—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system being a [4.4.0] system, e.g. hydrogenated naphthols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MA25300A 1997-10-17 1998-10-16 Derives d-homo-9, 10-secocholesta-23-yne-3,25-diol MA26554A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97118036 1997-10-17

Publications (1)

Publication Number Publication Date
MA26554A1 true MA26554A1 (fr) 2004-12-20

Family

ID=8227488

Family Applications (1)

Application Number Title Priority Date Filing Date
MA25300A MA26554A1 (fr) 1997-10-17 1998-10-16 Derives d-homo-9, 10-secocholesta-23-yne-3,25-diol

Country Status (8)

Country Link
US (1) US5919986A (fr)
AR (1) AR017339A1 (fr)
AU (1) AU9750398A (fr)
CO (1) CO4970801A1 (fr)
MA (1) MA26554A1 (fr)
PE (1) PE120899A1 (fr)
WO (1) WO1999020605A1 (fr)
ZA (1) ZA989431B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005515996A (ja) * 2001-12-03 2005-06-02 ノバセア インコーポレイティッド 活性型ビタミンｄ化合物を含む薬学的組成物
US20050101576A1 (en) * 2003-11-06 2005-05-12 Novacea, Inc. Methods of using vitamin D compounds in the treatment of myelodysplastic syndromes
US20050026877A1 (en) * 2002-12-03 2005-02-03 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
EA010437B1 (ru) * 2003-06-11 2008-08-29 Новацея, Инк. Фармацевтические композиции, содержащие активные соединения витамина d
US20050020546A1 (en) * 2003-06-11 2005-01-27 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
US20060189586A1 (en) * 2003-06-11 2006-08-24 Cleland Jeffrey L Pharmaceutical compositions comprising active vitamin D compounds
ES2593047T3 (es) 2006-02-03 2016-12-05 Opko Renal, Llc Tratamiento de la insuficiencia y deficiencia de vitamina D con 25-hidroxivitamina D2 y 25-hidroxivitamina D3
ES2670029T3 (es) 2006-06-21 2018-05-29 Opko Ireland Global Holdings, Ltd. Terapia usando agente de repleción de la vitamina D y agente de reemplazo de la hormona de la vitamina D
KR20190028822A (ko) 2007-04-25 2019-03-19 사이토크로마 인코포레이티드 비타민 ｄ 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물
US11752158B2 (en) 2007-04-25 2023-09-12 Eirgen Pharma Ltd. Method of treating vitamin D insufficiency and deficiency
CA2981549A1 (fr) * 2009-01-27 2010-08-05 Berg Llc Vitamines d3 et analogues de celles-ci pour soulagement des effets secondaires associes a une chimiotherapie
CN106265695B (zh) 2009-08-14 2021-05-07 博格有限责任公司 用于治疗脱发的维生素d3及其类似物
WO2011123476A1 (fr) 2010-03-29 2011-10-06 Cytochroma Inc. Procédés et compositions pour réduction de taux d'hormone parathyroïde
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
CN112156097A (zh) 2013-05-29 2021-01-01 博格有限责任公司 使用维生素d预防或减轻化疗诱发的脱发
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
JP7032322B2 (ja) 2016-03-28 2022-03-08 オプコ アイルランド グローバル ホールディングス リミテッド ビタミンｄ治療法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
DE69304279T2 (de) * 1992-05-20 1997-02-20 Hoffmann La Roche Fluorierte Analoge Vitamins D3
AU666563B2 (en) * 1992-08-07 1996-02-15 Wisconsin Alumni Research Foundation Preparation of 19-nor-vitamin D compounds
PT972762E (pt) * 1993-07-09 2004-02-27 Theramex Novos analogos estruturais da vitamina d
US5384314B1 (en) * 1994-03-11 1997-08-05 Hoffmann La Roche 1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
DE69606680T2 (de) * 1995-10-30 2000-08-17 F. Hoffmann-La Roche Ag, Basel 1-Alpha, 26-dihydroxy-D-homo-vitamin D3
TW403735B (en) * 1995-11-22 2000-09-01 Hoffmann La Roche 25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol

Also Published As

Publication number Publication date
ZA989431B (en) 1999-04-19
PE120899A1 (es) 1999-12-02
CO4970801A1 (es) 2000-11-07
AU9750398A (en) 1999-05-10
WO1999020605A1 (fr) 1999-04-29
AR017339A1 (es) 2001-09-05
US5919986A (en) 1999-07-06

Similar Documents

Publication Publication Date Title
DE69933287D1 (de) 12,13-modifizierte epothilon-derivate
ATE260243T1 (de) N-aroylphenylalaninderivate
ID22781A (id) Turunan-turunan nikotinamida
DK1000048T3 (da) Substituerede 1,2,3,4-tetrahydronapthalenderivater
DE69817186D1 (de) Diaminorhodamin-derivate
MA26504A1 (fr) Derives benzimidazole.
DK0930302T3 (da) Benzosulfonderivater
PT915088E (pt) Derivados de d-prolina
ATE259810T1 (de) Phenyl-xanthinderivate
ATE255098T1 (de) Substituierte chromanderivate
MA26554A1 (fr) Derives d-homo-9, 10-secocholesta-23-yne-3,25-diol
PT1003719E (pt) Derivados microbicidas de n-sulfonil-glicinalquiniloxifenemetilamida
ATE440854T1 (de) 5-deoxy-cytidin-derivate
ATE257484T1 (de) 6,9-verbrückte erythromycin-derivate
PT1027362E (pt) Derivados de cetolidos 2-halogeno-6-o-substituidos
ATE246199T1 (de) 3-descladinose-2,3-anhydroerythromycin-derivate
DE69814441D1 (de) 6,11-verbrückte erythromycinderivate
ATE255099T1 (de) Substituierte chromanderivate
NO20003825D0 (no) 1,3,4 - oxadiazolonderivater
DK0966437T3 (da) 5-Aroylnaphthalenderivater
ATE233253T1 (de) Chromanderivate
DE69829682D1 (de) Cis-disubstituierte aminocycloalkyl-pyrrolidin-derivate
MA26480A1 (fr) Derives de phenoxymethylpiperidine
DE69828780D1 (de) Amidinocamptpthecin-derivate
DK1015447T3 (da) Piperidinylmethyloxazolidinonderivat