MA26921A1 - Derives d'acides aminés cycliques utilisables en tant qu'agents pharmaceutiques. - Google Patents

Derives d'acides aminés cycliques utilisables en tant qu'agents pharmaceutiques.

Info

Publication number: MA26921A1
Authority: MA; Morocco
Prior art keywords: sub; compound; amino acid; acid derivatives; pharmaceutical agents
Prior art date: 2000-06-28

Application number

MA26977A

Other languages

English (en)

Inventor

David Clive Blakemore

Justin Stephen Bryans

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-28

Filing date

2002-12-24

Publication date

2004-12-20

2002-12-24 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

2004-12-20 Publication of MA26921A1 publication Critical patent/MA26921A1/fr

Links

150000003862 amino acid derivatives Chemical class 0.000 title 1
239000008177 pharmaceutical agent Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
YNCKAQVPQJWLJW-ZETCQYMHSA-N [(1r)-4-oxocyclopent-2-en-1-yl] acetate Chemical compound CC(=O)O[C@@H]1CC(=O)C=C1 YNCKAQVPQJWLJW-ZETCQYMHSA-N 0.000 abstract 1
YNCKAQVPQJWLJW-SSDOTTSWSA-N [(1s)-4-oxocyclopent-2-en-1-yl] acetate Chemical compound CC(=O)O[C@H]1CC(=O)C=C1 YNCKAQVPQJWLJW-SSDOTTSWSA-N 0.000 abstract 1
-1 acetoxy compound Chemical class 0.000 abstract 1
125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
239000012038 nucleophile Substances 0.000 abstract 1
125000002524 organometallic group Chemical group 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
- C07C45/676—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton by elimination of carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/69—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/385—Saturated compounds containing a keto group being part of a ring
- C07C49/395—Saturated compounds containing a keto group being part of a ring of a five-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

MA26977A 2000-06-28 2002-12-24 Derives d'acides aminés cycliques utilisables en tant qu'agents pharmaceutiques. MA26921A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB0015771A GB2364049A (en)	2000-06-28	2000-06-28	Cyclic ketones and their use in the synthesis of amino acids

Publications (1)

Publication Number	Publication Date
MA26921A1 true MA26921A1 (fr)	2004-12-20

Family

ID=9894534

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA26977A MA26921A1 (fr)	2000-06-28	2002-12-24	Derives d'acides aminés cycliques utilisables en tant qu'agents pharmaceutiques.

Country Status (24)

Country	Link
US (2)	US6872856B2 (fr)
EP (1)	EP1296921A1 (fr)
JP (1)	JP2004501884A (fr)
KR (1)	KR100778953B1 (fr)
CN (1)	CN1438985A (fr)
AP (1)	AP2002002699A0 (fr)
AU (2)	AU6620801A (fr)
BR (1)	BR0112076A (fr)
CA (1)	CA2411808A1 (fr)
EA (1)	EA200201202A1 (fr)
GB (1)	GB2364049A (fr)
HR (1)	HRP20021017A2 (fr)
HU (1)	HUP0301306A2 (fr)
IL (2)	IL153704A0 (fr)
IS (1)	IS6636A (fr)
MA (1)	MA26921A1 (fr)
MX (1)	MXPA03000076A (fr)
NO (1)	NO20026198L (fr)
NZ (1)	NZ523218A (fr)
OA (1)	OA12298A (fr)
PL (1)	PL359107A1 (fr)
WO (1)	WO2002000584A1 (fr)
YU (1)	YU93702A (fr)
ZA (1)	ZA200300243B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2364049A (en) *	2000-06-28	2002-01-16	Warner Lambert Co	Cyclic ketones and their use in the synthesis of amino acids
US6818787B2 (en)	2001-06-11	2004-11-16	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en)	2001-06-11	2007-06-19	Xenoport, Inc.	Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US7186855B2 (en)	2001-06-11	2007-03-06	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en)	2005-04-06	2011-11-01	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
WO2007010387A2 (fr) *	2005-07-18	2007-01-25	Pharmacia & Upjohn Company Llc	Synthese stereoselective de cyclopentanones 3,4-disubstitues et composes correspondants
CN102190536A (zh) *	2010-03-08	2011-09-21	华东理工大学	一种有机催化烯酮与有机膦化合物不对称共轭加成的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2460891C2 (de) *	1974-12-21	1982-09-23	Gödecke AG, 1000 Berlin	1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US4087544A (en) *	1974-12-21	1978-05-02	Warner-Lambert Company	Treatment of cranial dysfunctions using novel cyclic amino acids
US5254708A (en) *	1987-06-16	1993-10-19	Nissan Chemical Industries, Ltd.	Substituted cyclic ketones, substituted cyclic enones, and process for producing the same
US5134238A (en) *	1990-05-24	1992-07-28	Brigham Young University	Chiral copper amine complexes
US5480962A (en)	1993-07-22	1996-01-02	Eastman Chemical Company	Copolyesters having repeat units derived from succinic acid
HUP0004310A3 (en)	1997-10-27	2001-11-28	Warner Lambert Co	Cyclic amino acids, and derivatives thereof and pharmaceutical compositions comprising the said compounds as active agents
GB2364049A (en) *	2000-06-28	2002-01-16	Warner Lambert Co	Cyclic ketones and their use in the synthesis of amino acids

2000
- 2000-06-28 GB GB0015771A patent/GB2364049A/en not_active Withdrawn
2001
- 2001-06-28 CN CN01811912A patent/CN1438985A/zh active Pending
- 2001-06-28 AP APAP/P/2002/002699A patent/AP2002002699A0/en unknown
- 2001-06-28 CA CA002411808A patent/CA2411808A1/fr not_active Abandoned
- 2001-06-28 WO PCT/GB2001/002900 patent/WO2002000584A1/fr not_active Ceased
- 2001-06-28 EP EP01943670A patent/EP1296921A1/fr not_active Withdrawn
- 2001-06-28 BR BR0112076-0A patent/BR0112076A/pt not_active IP Right Cessation
- 2001-06-28 EA EA200201202A patent/EA200201202A1/ru unknown
- 2001-06-28 OA OA1200200391A patent/OA12298A/en unknown
- 2001-06-28 IL IL15370401A patent/IL153704A0/xx unknown
- 2001-06-28 AU AU6620801A patent/AU6620801A/xx active Pending
- 2001-06-28 PL PL01359107A patent/PL359107A1/xx not_active IP Right Cessation
- 2001-06-28 YU YU93702A patent/YU93702A/sh unknown
- 2001-06-28 JP JP2002505335A patent/JP2004501884A/ja not_active Withdrawn
- 2001-06-28 AU AU2001266208A patent/AU2001266208B2/en not_active Ceased
- 2001-06-28 MX MXPA03000076A patent/MXPA03000076A/es active IP Right Grant
- 2001-06-28 NZ NZ523218A patent/NZ523218A/en unknown
- 2001-06-28 HU HU0301306A patent/HUP0301306A2/hu unknown
- 2001-06-28 KR KR1020027017858A patent/KR100778953B1/ko not_active Expired - Fee Related
- 2001-06-28 HR HR20021017A patent/HRP20021017A2/xx not_active Application Discontinuation
- 2001-06-28 US US10/312,065 patent/US6872856B2/en not_active Expired - Fee Related
2002
- 2002-11-28 IS IS6636A patent/IS6636A/is unknown
- 2002-12-23 NO NO20026198A patent/NO20026198L/no not_active Application Discontinuation
- 2002-12-24 MA MA26977A patent/MA26921A1/fr unknown
2003
- 2003-01-09 ZA ZA200300243A patent/ZA200300243B/en unknown
2005
- 2005-03-07 US US11/074,250 patent/US20050215816A1/en not_active Abandoned
2008
- 2008-03-27 IL IL190490A patent/IL190490A0/en unknown

Also Published As

Publication number	Publication date
US20050215816A1 (en)	2005-09-29
EA200201202A1 (ru)	2003-06-26
IL190490A0 (en)	2008-11-03
NO20026198D0 (no)	2002-12-23
GB2364049A (en)	2002-01-16
AU2001266208B2 (en)	2006-11-23
JP2004501884A (ja)	2004-01-22
HRP20021017A2 (en)	2004-02-29
PL359107A1 (en)	2004-08-23
MXPA03000076A (es)	2003-10-15
EP1296921A1 (fr)	2003-04-02
IL153704A0 (en)	2003-07-06
US20030187296A1 (en)	2003-10-02
WO2002000584A1 (fr)	2002-01-03
CA2411808A1 (fr)	2002-01-03
ZA200300243B (en)	2004-06-14
GB0015771D0 (en)	2000-08-16
HUP0301306A2 (hu)	2003-08-28
CN1438985A (zh)	2003-08-27
OA12298A (en)	2004-03-18
US6872856B2 (en)	2005-03-29
YU93702A (sh)	2006-08-17
AU6620801A (en)	2002-01-08
KR100778953B1 (ko)	2007-11-27
NZ523218A (en)	2004-06-25
IS6636A (is)	2002-11-28
AP2002002699A0 (en)	2002-12-31
NO20026198L (no)	2002-12-23
BR0112076A (pt)	2003-09-02
KR20030016311A (ko)	2003-02-26

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