MA27341A1 - NOUVEAUX DERIVES DE PYRROLO[3,4-c]CARBAZOLE ET DE PYRIDO[2,3-b]PYRROLO[3,4-e]INDOLE, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT . - Google Patents
NOUVEAUX DERIVES DE PYRROLO[3,4-c]CARBAZOLE ET DE PYRIDO[2,3-b]PYRROLO[3,4-e]INDOLE, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT .Info
- Publication number
- MA27341A1 MA27341A1 MA28180A MA28180A MA27341A1 MA 27341 A1 MA27341 A1 MA 27341A1 MA 28180 A MA28180 A MA 28180A MA 28180 A MA28180 A MA 28180A MA 27341 A1 MA27341 A1 MA 27341A1
- Authority
- MA
- Morocco
- Prior art keywords
- pyrrolo
- group
- pyrido
- carbazole
- preparation
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- GAAWKLUURLVNGE-UHFFFAOYSA-N pyrrolo[3,4-c]carbazole Chemical compound C1=CC=C2C3=C4C=NC=C4C=CC3=NC2=C1 GAAWKLUURLVNGE-UHFFFAOYSA-N 0.000 title abstract 2
- YFFFKJJIYIHOKM-UHFFFAOYSA-N 4,10,12-triazatetracyclo[7.7.0.02,6.011,16]hexadeca-1,3,5,7,9,11(16),12,14-octaene Chemical class C1=CC=C2C3=C4C=NC=C4C=CC3=NC2=N1 YFFFKJJIYIHOKM-UHFFFAOYSA-N 0.000 title 1
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical class [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 abstract 2
- -1 atom hydrogen Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 abstract 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
Abstract
Nouveaux dérivés de pyrrolo[3,4-c)carbazole et de pyrido[2,3-blpyrrolo[3,4-e]indole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent Composés de formule (I) : dans laquelle : „ Z représente un groupement de formule U-V telle que définie dans la description, „ W1 représente, avec les atomes de carbone auxquels il est lié, un groupement phényle ou un groupement pyridinyle, „ W2 est tel que défini dans la description, „ X1, X2 représentent chacun un atome d'hydrogène, un groupement hydroxy, alkoxy, mercapto ou alkylthio, „ Y1, Y2 représentent chacun un atome d'hydrogène, „ ou X1 et Y1, X2 et Y2 représentent chacun un groupement choisi parmi atome d'hydrogène, groupement hydroxy, alkoxy (C1-C6,) linéaire ou ramifié, mercapto, et alkylthio (C1-C6) linéaire ou ramifié, „ R1 est tel que défini dans la description, „ Q représente un atome d'oxygène ou un groupement NR2 tel que défini dans la description. Médicaments.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0212846A FR2845995A1 (fr) | 2002-10-16 | 2002-10-16 | Nouveaux derives de pyrrolo[3,4-c]carbazole et de pyrido[2,3-b]pyrrolo[3,4-e]indole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA27341A1 true MA27341A1 (fr) | 2005-05-02 |
Family
ID=32050428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA28180A MA27341A1 (fr) | 2002-10-16 | 2005-03-30 | NOUVEAUX DERIVES DE PYRROLO[3,4-c]CARBAZOLE ET DE PYRIDO[2,3-b]PYRROLO[3,4-e]INDOLE, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT . |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20060004428A1 (fr) |
| EP (1) | EP1554277A1 (fr) |
| JP (1) | JP2006507269A (fr) |
| KR (1) | KR20050088279A (fr) |
| CN (1) | CN1705667A (fr) |
| AR (1) | AR041617A1 (fr) |
| AU (1) | AU2003285397A1 (fr) |
| BR (1) | BR0315490A (fr) |
| CA (1) | CA2502515A1 (fr) |
| EA (1) | EA200500572A1 (fr) |
| FR (1) | FR2845995A1 (fr) |
| MA (1) | MA27341A1 (fr) |
| MX (1) | MXPA05003977A (fr) |
| MY (1) | MY134202A (fr) |
| NO (1) | NO20052338D0 (fr) |
| PL (1) | PL375958A1 (fr) |
| WO (1) | WO2004035582A1 (fr) |
| ZA (1) | ZA200502830B (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI499414B (zh) | 2006-09-29 | 2015-09-11 | Lexicon Pharmaceuticals Inc | 鈉與葡萄糖第２型共同運輸體（ｃｏ-ｔｒａｎｓｐｏｒｔｅｒ ２）的抑制物與其應用方法 |
| WO2008109591A1 (fr) | 2007-03-08 | 2008-09-12 | Lexicon Pharmaceuticals, Inc. | Analogues de phlorizine utilisés comme inhibiteurs du co-transporteur 2 du sodium-glucose |
| CN103242404A (zh) * | 2012-02-03 | 2013-08-14 | 复旦大学 | N-鼠李糖基苯并咔唑化合物及其合成方法和在制药中的用途 |
| CA3180677A1 (fr) * | 2020-04-24 | 2021-10-28 | The University Of British Columbia | Agents anti-viraux, leurs utilisations et leurs procedes de preparation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU758241B2 (en) * | 1998-03-13 | 2003-03-20 | University Of British Columbia, The | Granulatimide derivatives for use in cancer treatment |
-
2002
- 2002-10-16 FR FR0212846A patent/FR2845995A1/fr not_active Withdrawn
-
2003
- 2003-09-26 MY MYPI20033681A patent/MY134202A/en unknown
- 2003-10-14 EP EP03778389A patent/EP1554277A1/fr not_active Withdrawn
- 2003-10-14 KR KR1020057006601A patent/KR20050088279A/ko not_active Ceased
- 2003-10-14 BR BR0315490-4A patent/BR0315490A/pt not_active IP Right Cessation
- 2003-10-14 PL PL03375958A patent/PL375958A1/xx not_active Application Discontinuation
- 2003-10-14 CN CNA2003801015771A patent/CN1705667A/zh active Pending
- 2003-10-14 CA CA002502515A patent/CA2502515A1/fr not_active Abandoned
- 2003-10-14 WO PCT/FR2003/003021 patent/WO2004035582A1/fr not_active Ceased
- 2003-10-14 US US10/531,620 patent/US20060004428A1/en not_active Abandoned
- 2003-10-14 JP JP2004544379A patent/JP2006507269A/ja active Pending
- 2003-10-14 AU AU2003285397A patent/AU2003285397A1/en not_active Abandoned
- 2003-10-14 EA EA200500572A patent/EA200500572A1/ru unknown
- 2003-10-14 MX MXPA05003977A patent/MXPA05003977A/es not_active Application Discontinuation
- 2003-10-15 AR ARP030103743A patent/AR041617A1/es unknown
-
2005
- 2005-03-30 MA MA28180A patent/MA27341A1/fr unknown
- 2005-04-07 ZA ZA200502830A patent/ZA200502830B/en unknown
- 2005-05-12 NO NO20052338A patent/NO20052338D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MY134202A (en) | 2007-11-30 |
| JP2006507269A (ja) | 2006-03-02 |
| NO20052338L (no) | 2005-05-12 |
| AU2003285397A1 (en) | 2004-05-04 |
| ZA200502830B (en) | 2006-07-26 |
| MXPA05003977A (es) | 2005-06-22 |
| CN1705667A (zh) | 2005-12-07 |
| BR0315490A (pt) | 2005-08-23 |
| NO20052338D0 (no) | 2005-05-12 |
| US20060004428A1 (en) | 2006-01-05 |
| KR20050088279A (ko) | 2005-09-05 |
| EA200500572A1 (ru) | 2005-12-29 |
| EP1554277A1 (fr) | 2005-07-20 |
| WO2004035582A1 (fr) | 2004-04-29 |
| FR2845995A1 (fr) | 2004-04-23 |
| CA2502515A1 (fr) | 2004-04-29 |
| AR041617A1 (es) | 2005-05-26 |
| PL375958A1 (en) | 2005-12-12 |
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