MA27720A1 - Dérivés d'acide 3-(1-[3-(1,3-benzothiazole-6-yl)propylcarbamoyl]cycloalkyl)propano??que servant d'inhibiteurs de NEP - Google Patents

Dérivés d'acide 3-(1-[3-(1,3-benzothiazole-6-yl)propylcarbamoyl]cycloalkyl)propano??que servant d'inhibiteurs de NEP

Info

Publication number
MA27720A1
MA27720A1 MA28498A MA28498A MA27720A1 MA 27720 A1 MA27720 A1 MA 27720A1 MA 28498 A MA28498 A MA 28498A MA 28498 A MA28498 A MA 28498A MA 27720 A1 MA27720 A1 MA 27720A1
Authority
MA
Morocco
Prior art keywords
disorder
sexual
dysfunction
male
female
Prior art date
Application number
MA28498A
Other languages
English (en)
Inventor
David Hepworth
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0305916A external-priority patent/GB0305916D0/en
Priority claimed from GB0329143A external-priority patent/GB0329143D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of MA27720A1 publication Critical patent/MA27720A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
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    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
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    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
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    • A61P9/12—Antihypertensives

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  • Organic Chemistry (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Biomedical Technology (AREA)
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  • Diabetes (AREA)
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  • Cardiology (AREA)
  • Psychiatry (AREA)
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  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
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  • Dermatology (AREA)
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  • Child & Adolescent Psychology (AREA)
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  • Gastroenterology & Hepatology (AREA)

Abstract

l'hypercalciurie, un ictus, le glaucome, l'obésité, des maladies métaboliques, le syndrome métabolique, le diabète, la tolérance entravée au glucose, la rétinopathie diabétique, la neuropathie diabétique, des troubles menstruels, l'accouchement avant terme, la pré-éclampsie, l'endométriose et des troubles de la reproduction, la stérilité masculine et la stérilité féminine, le syndrome d'ovaire polykystique, un défaut d'implantation, l'asthme, l'inflammation, la leucémie, la douleur, la douleur provoquée par un cancer, la dépression, la pharmacodépendance, la cirrhose, l'épilepsie, des troubles affectifs, la démence et la confusion gériatrique, des troubles gastro-intestinaux, la diarrhée, le syndrome du côlon irritable, la cicatrisation de plaies, les ulcères diabétiques et les ulcères veineux et les escarres de décubitus, le choc septique, la sécrétion d'acide gastrique, l'hyperréninémie, la fibrose kystique, une resténose, l'athérosclérose, un dysfonctionnement sexuel féminin (FSD), un trouble d'éveil sexuel, un trouble d'éveil sexuel féminin (FSAD), un dysfonctionnement sexuel masculin (MSD), un dysfonctionnement de l'érection masculine (MED), un trouble de désir sexuel hypoactif, un trouble orgasmique et un trouble douloureux sexuel. 13. Composé, méthode ou utilisation suivant la revendication 12, dans lequel le trouble ou l'affection est choisi entre un dysfonctionnement sexuel féminin (FSD), un trouble d'éveil sexuel, un trouble d'éveil sexuel féminin (FSAD), un dysfonctionnement sexuel masculin (MSD), un dysfonctionnement de l'érection masculine (MED), un trouble de désir sexuel hypoactif, un trouble orgasmique et un trouble douloureux sexuel. 14. Composé, méthode ou utilisation suivant la revendication 13, dans lequel le trouble ou l'affection est choisi entre un dysfonctionnement sexuel féminin (FSD), un trouble d'éveil sexuel féminin (FSAD), un dysfonctionnement sexuel masculin (MSD) et un dysfonctionnement, de l'érection masculine (MED).
MA28498A 2003-03-14 2005-09-14 Dérivés d'acide 3-(1-[3-(1,3-benzothiazole-6-yl)propylcarbamoyl]cycloalkyl)propano??que servant d'inhibiteurs de NEP MA27720A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0305916A GB0305916D0 (en) 2003-03-14 2003-03-14 New N-phenpropylcyclopentyl-substituted glutaramide derivatives as NEP inhibitors
GB0329143A GB0329143D0 (en) 2003-12-16 2003-12-16 Novel pharmaceuticals

Publications (1)

Publication Number Publication Date
MA27720A1 true MA27720A1 (fr) 2006-01-02

Family

ID=32992599

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28498A MA27720A1 (fr) 2003-03-14 2005-09-14 Dérivés d'acide 3-(1-[3-(1,3-benzothiazole-6-yl)propylcarbamoyl]cycloalkyl)propano??que servant d'inhibiteurs de NEP

Country Status (25)

Country Link
US (1) US20040180941A1 (fr)
EP (1) EP1606272A1 (fr)
JP (1) JP3923512B2 (fr)
KR (1) KR20050110003A (fr)
AP (1) AP2005003393A0 (fr)
AR (1) AR043551A1 (fr)
AU (1) AU2004220269A1 (fr)
BR (1) BRPI0408377A (fr)
CA (1) CA2519072A1 (fr)
CL (1) CL2004000512A1 (fr)
EA (1) EA200501204A1 (fr)
EC (1) ECSP056017A (fr)
HR (1) HRP20050797A2 (fr)
IS (1) IS8003A (fr)
MA (1) MA27720A1 (fr)
MX (1) MXPA05009788A (fr)
NL (1) NL1025709C2 (fr)
NO (1) NO20054169L (fr)
OA (1) OA13039A (fr)
PA (1) PA8597401A1 (fr)
PE (1) PE20050310A1 (fr)
TN (1) TNSN05227A1 (fr)
TW (1) TW200504038A (fr)
UY (1) UY28226A1 (fr)
WO (1) WO2004080985A1 (fr)

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WO2006027680A1 (fr) * 2004-09-10 2006-03-16 Pfizer Limited Derives d'acide 3-(1-carbamoylcyclohexyl)propionique comme inhibiteurs de l'enzyme endopeptidase neutre
WO2006066361A1 (fr) * 2004-12-24 2006-06-29 The University Of Queensland Procede de traitement ou prophylaxie
JP2009502961A (ja) 2005-07-29 2009-01-29 コンサート ファーマシューティカルズ インコーポレイテッド 新規な医薬組成物
US20070178141A1 (en) * 2005-09-07 2007-08-02 Bebaas, Inc. Vitamin B12 compositions
US20130131007A1 (en) 2005-09-07 2013-05-23 Bebaas, Inc. Vitamin b12 compositions
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WO2008021666A2 (fr) * 2006-08-18 2008-02-21 Morton Grove Pharmaceuticals, Inc. Compositions stables de lévétiracétam et procédés
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WO2019241588A1 (fr) * 2018-06-14 2019-12-19 Astrazeneca Uk Limited Méthodes de traitement d'une dysfonction érectile avec une composition pharmaceutique d'inhibiteur de phosphodiestérase 5 spécifique de cgmp
WO2019241585A1 (fr) * 2018-06-14 2019-12-19 Astrazeneca Uk Limited Méthodes de traitement d'une dysfonction érectile avec une composition pharmaceutique d'inhibiteur de phosphodiestérase 5 spécifique de cgmp
SG11202102791SA (en) 2018-09-25 2021-04-29 Antabio Sas Indane derivatives for use in the treatment of bacterial infection
IL292775A (en) * 2019-11-08 2022-07-01 Vella Bioscience Inc preparations containing cannabidiol (cbd) that act peripherally and their use to improve female sexual function or to treat female sexual disorders
GB202402524D0 (en) * 2024-02-22 2024-04-10 Futura Medical Developments Ltd Topical composition

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PE20050310A1 (es) 2005-05-04
AR043551A1 (es) 2005-08-03
HRP20050797A2 (en) 2006-02-28
IS8003A (is) 2005-08-29
AU2004220269A1 (en) 2004-09-23
OA13039A (en) 2006-11-10
PA8597401A1 (es) 2005-05-24
NL1025709A1 (nl) 2004-09-16
CL2004000512A1 (es) 2005-01-21
WO2004080985A1 (fr) 2004-09-23
NO20054169L (no) 2005-12-07
EA200501204A1 (ru) 2006-06-30
NL1025709C2 (nl) 2005-03-14
US20040180941A1 (en) 2004-09-16
TNSN05227A1 (fr) 2007-06-11
JP2006526572A (ja) 2006-11-24
EP1606272A1 (fr) 2005-12-21
MXPA05009788A (es) 2005-10-26
TW200504038A (en) 2005-02-01
JP3923512B2 (ja) 2007-06-06
BRPI0408377A (pt) 2006-03-21
NO20054169D0 (no) 2005-09-07
ECSP056017A (es) 2006-01-27
UY28226A1 (es) 2004-11-08
AP2005003393A0 (en) 2005-09-30
CA2519072A1 (fr) 2004-09-23
KR20050110003A (ko) 2005-11-22

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