MA27760A1 - Enduit a ongles antifongique et procede d'utilisation - Google Patents
Enduit a ongles antifongique et procede d'utilisationInfo
- Publication number
- MA27760A1 MA27760A1 MA28543A MA28543A MA27760A1 MA 27760 A1 MA27760 A1 MA 27760A1 MA 28543 A MA28543 A MA 28543A MA 28543 A MA28543 A MA 28543A MA 27760 A1 MA27760 A1 MA 27760A1
- Authority
- MA
- Morocco
- Prior art keywords
- fungicidal
- composition
- coat
- amount
- antifungal
- Prior art date
Links
- 229940121375 antifungal agent Drugs 0.000 title abstract 4
- 230000000843 anti-fungal effect Effects 0.000 title abstract 3
- 239000011248 coating agent Substances 0.000 title abstract 2
- 238000000576 coating method Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000000855 fungicidal effect Effects 0.000 abstract 3
- 206010017533 Fungal infection Diseases 0.000 abstract 1
- 208000031888 Mycoses Diseases 0.000 abstract 1
- 208000010195 Onychomycosis Diseases 0.000 abstract 1
- 239000003429 antifungal agent Substances 0.000 abstract 1
- 230000009977 dual effect Effects 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 229920001477 hydrophilic polymer Polymers 0.000 abstract 1
- 239000003961 penetration enhancing agent Substances 0.000 abstract 1
- 201000005882 tinea unguium Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q3/00—Manicure or pedicure preparations
- A61Q3/02—Nail coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/806—Drug, bio-affecting and body treating compositions involving IgM
- Y10S424/807—Monoclonal
- Y10S424/808—Human
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
L'invention concerne une composition d'enduit à ongles antifongique à double effet et un procédé d'utilisation afin d'améliorer ou d'empêcher une infection fongique des ongles et en particulier onychomycose. L'invention concerne en outre des compositions de type monocouche et double couche convenables pour des applications quotidiennes fongicides. Une composition d'enduit à ongles antifongique préférée contient une quantité efficace de fongicide, une quantité d'un promoteur de perméation sensiblement non volatil, une quantité d'un polymère hydrophile, formant une couche, et un support volatile pharmaceutiquement acceptable. Cette composition fournit un enduit fongicide sensiblement soluble dans l'eau après mise en contact avec une ongle susceptible d'infections fongiques ou ayant une infection fongique.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45668403P | 2003-03-21 | 2003-03-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA27760A1 true MA27760A1 (fr) | 2006-02-01 |
Family
ID=33098141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA28543A MA27760A1 (fr) | 2003-03-21 | 2005-10-11 | Enduit a ongles antifongique et procede d'utilisation |
Country Status (28)
| Country | Link |
|---|---|
| US (3) | US7462362B2 (fr) |
| EP (2) | EP2106805B1 (fr) |
| JP (1) | JP4540667B2 (fr) |
| KR (1) | KR101093990B1 (fr) |
| CN (2) | CN102973420A (fr) |
| AT (2) | ATE432087T1 (fr) |
| AU (1) | AU2004224326B2 (fr) |
| BR (1) | BRPI0408613A (fr) |
| CA (1) | CA2519705C (fr) |
| CO (1) | CO5640092A2 (fr) |
| CY (1) | CY1111773T1 (fr) |
| DE (1) | DE602004021253D1 (fr) |
| DK (2) | DK2106805T3 (fr) |
| EC (1) | ECSP056110A (fr) |
| ES (1) | ES2366273T3 (fr) |
| HR (1) | HRP20050918A2 (fr) |
| IL (1) | IL170963A (fr) |
| IS (1) | IS8078A (fr) |
| MA (1) | MA27760A1 (fr) |
| MX (1) | MXPA05010114A (fr) |
| NO (1) | NO335895B1 (fr) |
| NZ (1) | NZ542904A (fr) |
| PL (1) | PL2106805T3 (fr) |
| RU (1) | RU2358718C2 (fr) |
| SG (1) | SG152065A1 (fr) |
| TN (1) | TNSN05231A1 (fr) |
| WO (1) | WO2004084826A2 (fr) |
| ZA (1) | ZA200507972B (fr) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050238672A1 (en) * | 2004-04-27 | 2005-10-27 | Nimni Marcel E | Antifungal drug delivery |
| MX2007006833A (es) * | 2004-12-10 | 2007-10-08 | Talima Therapeutics Inc | Composiciones y metodos para tratar condiciones de la unidad de una. |
| US20060275230A1 (en) * | 2004-12-10 | 2006-12-07 | Frank Kochinke | Compositions and methods for treating conditions of the nail unit |
| EP1698336A1 (fr) * | 2005-03-01 | 2006-09-06 | Ferrer Internacional, S.A. | Compositions antifongiques comprenant le sertaconazole ainsi que l' hydrocortisone ou un agent antibactérien |
| FR2892023B1 (fr) * | 2005-10-14 | 2009-09-25 | Galderma Sa | Composition pharmaceutique a base d'amorolfine et d'agent filmogene hydrosoluble pour application ungueale et peri-ungueale |
| AU2006332425A1 (en) * | 2006-01-02 | 2007-07-12 | Tlt Medical Ltd. | Pharmaceutical composition for the treatment of nail diseases |
| WO2007098591A2 (fr) * | 2006-03-02 | 2007-09-07 | Nuvo Research Inc. | Formulation topique pour les ongles |
| MX2008011435A (es) | 2006-03-08 | 2009-02-03 | Nihon Nohyaku Co Ltd | Composicion farmaceutica para uso externo. |
| US8058303B2 (en) | 2006-03-08 | 2011-11-15 | Nihon Nohyaku Co, Ltd | Pharmaceutical composition for external use |
| AU2006339841B2 (en) * | 2006-03-08 | 2012-08-30 | Nihon Nohyaku Co., Ltd. | Pharmaceutical composition for external use |
| JP5529539B2 (ja) | 2007-09-05 | 2014-06-25 | 株式会社ポーラファルマ | 医薬組成物 |
| JP5453093B2 (ja) | 2007-09-05 | 2014-03-26 | 株式会社ポーラファルマ | 抗真菌医薬組成物 |
| JP5345937B2 (ja) | 2007-09-05 | 2013-11-20 | 株式会社ポーラファルマ | 抗真菌組成物 |
| US20090175810A1 (en) * | 2008-01-03 | 2009-07-09 | Gareth Winckle | Compositions and methods for treating diseases of the nail |
| CA2739376A1 (fr) | 2008-10-03 | 2010-04-08 | Nexmed Holdings, Inc. | Composition stabilisee pour traiter le psoriasis |
| CN102256602A (zh) * | 2008-10-21 | 2011-11-23 | 诺沃德米克斯国际有限公司 | 用于治疗上皮组织的组合物 |
| WO2010047288A1 (fr) | 2008-10-24 | 2010-04-29 | Semiconductor Energy Laboratory Co., Ltd. | Procédé de fabrication d’un dispositif semi-conducteur |
| CN108191846B (zh) * | 2008-12-04 | 2021-08-20 | 于崇曦 | 高穿透性组合物及其应用 |
| US20100291182A1 (en) * | 2009-01-21 | 2010-11-18 | Arsenal Medical, Inc. | Drug-Loaded Fibers |
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| WO2010086727A1 (fr) * | 2009-01-30 | 2010-08-05 | Galderma Pharma Sa | Compositions stables pour le traitement de l'onychomycose des ongles |
| US10130610B2 (en) | 2009-04-09 | 2018-11-20 | Pola Pharma Inc. | Antimycotic pharmaceutical composition |
| EP2416758B8 (fr) | 2009-04-09 | 2017-10-18 | Pola Pharma Inc. | Composition pharmaceutique antimycotique |
| WO2011014850A2 (fr) | 2009-07-31 | 2011-02-03 | Nuvo Research Inc. | Formulations à usage topique à base d'un eutectique |
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| US12544491B2 (en) | 2009-08-24 | 2026-02-10 | Arsenal Medical, Inc. | In situ forming hemostatic foam implants |
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| WO2011024620A1 (fr) | 2009-08-25 | 2011-03-03 | Pola Pharma Inc. | Composition pharmaceutique antimycotique |
| JPWO2011052224A1 (ja) * | 2009-11-02 | 2013-03-14 | 株式会社福元技研 | 皮膚美容用混練組成物およびその製造方法、皮膚美容用混練組成物の使用方法 |
| AU2010336441B2 (en) | 2009-12-23 | 2015-02-05 | Nuvo Research Inc. | Highly permeating terbinafine formulation for treating onychomycosis |
| SG10201600228QA (en) * | 2010-05-04 | 2016-03-30 | Nexmed Holdings Inc | Therapeutic peptide composition and method |
| CN102858158A (zh) | 2010-05-04 | 2013-01-02 | 尼克美控股公司 | 小分子治疗剂的组合物 |
| US8039494B1 (en) | 2010-07-08 | 2011-10-18 | Dow Pharmaceutical Sciences, Inc. | Compositions and methods for treating diseases of the nail |
| RU2432158C1 (ru) * | 2010-07-28 | 2011-10-27 | Закрытое акционерное общество "Институт прикладной нанотехнологии" | Профилактический бактерицидный лак для обработки ногтей |
| EP2646015B1 (fr) * | 2010-12-02 | 2020-04-22 | Ferring International Center S.A. | Énantiomère actif du 2-(n,n-diméthylamino)-propionate dodécylique |
| US9034240B2 (en) | 2011-01-31 | 2015-05-19 | Arsenal Medical, Inc. | Electrospinning process for fiber manufacture |
| US9194058B2 (en) | 2011-01-31 | 2015-11-24 | Arsenal Medical, Inc. | Electrospinning process for manufacture of multi-layered structures |
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| EP2707007B1 (fr) * | 2011-05-11 | 2018-03-07 | Veloce BioPharma LLC | Compositions antifongiques pour le traitement des ongles |
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| CA2775393C (fr) * | 2012-05-02 | 2014-04-29 | Samy Saad | Formulations pharmaceutiques topiques non aqueuses |
| US20150209301A1 (en) | 2012-07-30 | 2015-07-30 | Nichiban Company Limited | Patch for anti-dermatophytosis |
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| WO2014159930A1 (fr) * | 2013-03-14 | 2014-10-02 | Alc Therapeutics, Llc | Compositions antimycosiques pour le traitement de surinfections de la peau et des ongles |
| GB201317005D0 (en) * | 2013-09-25 | 2013-11-06 | Blueberry Therapeutics Ltd | Composition and methods of treatment |
| MX363386B (es) | 2013-10-03 | 2019-03-20 | Dow Pharmaceutical Sciences | Formulaciones de efinaconazol estabilizadas. |
| KR102612453B1 (ko) | 2013-11-22 | 2023-12-08 | 다우 파마슈티컬 사이언시즈, 인코포레이티드 | 항감염 방법,조성물,및 장치 |
| EP2952208A1 (fr) * | 2014-06-04 | 2015-12-09 | Universidade de Santiago de Compostela | Système hydroalcoolique de traitement des ongles |
| WO2016024602A1 (fr) | 2014-08-13 | 2016-02-18 | Meiji Seikaファルマ株式会社 | Médicament anti-trichophyton cristallin et son procédé de production |
| KR20180011882A (ko) | 2015-01-20 | 2018-02-02 | 벨로체 바이오파르마 엘엘씨 | 신규한 요오드포 조성물 및 사용 방법 |
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| JP2005503318A (ja) | 2000-02-16 | 2005-02-03 | ベントレー ファーマシューティカルズ インコーポレイテッド | 医薬組成物 |
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-
2004
- 2004-03-22 DK DK09006962.6T patent/DK2106805T3/da active
- 2004-03-22 EP EP09006962A patent/EP2106805B1/fr not_active Expired - Lifetime
- 2004-03-22 SG SG200705758-1A patent/SG152065A1/en unknown
- 2004-03-22 HR HR20050918A patent/HRP20050918A2/xx not_active Application Discontinuation
- 2004-03-22 MX MXPA05010114A patent/MXPA05010114A/es active IP Right Grant
- 2004-03-22 US US10/514,190 patent/US7462362B2/en not_active Expired - Fee Related
- 2004-03-22 DK DK04757958T patent/DK1635770T3/da active
- 2004-03-22 WO PCT/US2004/008618 patent/WO2004084826A2/fr not_active Ceased
- 2004-03-22 EP EP04757958A patent/EP1635770B1/fr not_active Expired - Lifetime
- 2004-03-22 JP JP2006507422A patent/JP4540667B2/ja not_active Expired - Fee Related
- 2004-03-22 AT AT04757958T patent/ATE432087T1/de not_active IP Right Cessation
- 2004-03-22 AT AT09006962T patent/ATE512672T1/de active
- 2004-03-22 NZ NZ542904A patent/NZ542904A/en not_active IP Right Cessation
- 2004-03-22 ES ES09006962T patent/ES2366273T3/es not_active Expired - Lifetime
- 2004-03-22 RU RU2005132390/15A patent/RU2358718C2/ru not_active IP Right Cessation
- 2004-03-22 BR BRPI0408613-9A patent/BRPI0408613A/pt not_active IP Right Cessation
- 2004-03-22 AU AU2004224326A patent/AU2004224326B2/en not_active Ceased
- 2004-03-22 CN CN2012103745731A patent/CN102973420A/zh active Pending
- 2004-03-22 KR KR1020057017676A patent/KR101093990B1/ko not_active Expired - Fee Related
- 2004-03-22 CA CA2519705A patent/CA2519705C/fr not_active Expired - Fee Related
- 2004-03-22 PL PL09006962T patent/PL2106805T3/pl unknown
- 2004-03-22 CN CNA2004800135639A patent/CN1791378A/zh active Pending
- 2004-03-22 DE DE602004021253T patent/DE602004021253D1/de not_active Expired - Lifetime
-
2005
- 2005-09-19 TN TNP2005000231A patent/TNSN05231A1/fr unknown
- 2005-09-19 IL IL170963A patent/IL170963A/en not_active IP Right Cessation
- 2005-10-03 ZA ZA200507972A patent/ZA200507972B/en unknown
- 2005-10-11 MA MA28543A patent/MA27760A1/fr unknown
- 2005-10-18 IS IS8078A patent/IS8078A/is unknown
- 2005-10-19 NO NO20054830A patent/NO335895B1/no not_active IP Right Cessation
- 2005-10-20 EC EC2005006110A patent/ECSP056110A/es unknown
- 2005-10-21 CO CO05107315A patent/CO5640092A2/es not_active Application Discontinuation
-
2008
- 2008-12-09 US US12/316,009 patent/US20090099266A1/en not_active Abandoned
-
2011
- 2011-08-18 CY CY20111100797T patent/CY1111773T1/el unknown
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2013
- 2013-08-09 US US13/963,898 patent/US20130323189A1/en not_active Abandoned
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