MA27982A1 - Preparation de peptides somatostatine - Google Patents

Preparation de peptides somatostatine

Info

Publication number
MA27982A1
MA27982A1 MA28779A MA28779A MA27982A1 MA 27982 A1 MA27982 A1 MA 27982A1 MA 28779 A MA28779 A MA 28779A MA 28779 A MA28779 A MA 28779A MA 27982 A1 MA27982 A1 MA 27982A1
Authority
MA
Morocco
Prior art keywords
preparation
somatostatin peptides
somatostatin
peptides
wietfeld
Prior art date
Application number
MA28779A
Other languages
English (en)
Inventor
Heribert Hellstern
Werner Pachinger
Walter Prikoszovich
Bernhard Wietfeld
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA27982A1 publication Critical patent/MA27982A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

" PREPARATION DE PEPTIDES DE SOMATOSTATINE " Invention de : HELLSTERN, Heribert PACHINGER, Werner PRIKOSZOVICH, Walter WIETFELD, Bernhard Il est fourni un procédé pour préparer des analogues de somatostatine cycliques et les intermédiaires linéaires utilisés dans le procédé.
MA28779A 2003-08-08 2006-02-07 Preparation de peptides somatostatine MA27982A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0318682.2A GB0318682D0 (en) 2003-08-08 2003-08-08 Organic compounds

Publications (1)

Publication Number Publication Date
MA27982A1 true MA27982A1 (fr) 2006-07-03

Family

ID=27839906

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28779A MA27982A1 (fr) 2003-08-08 2006-02-07 Preparation de peptides somatostatine

Country Status (34)

Country Link
US (1) US7615609B2 (fr)
EP (1) EP1654280B8 (fr)
JP (1) JP4580928B2 (fr)
KR (1) KR101136633B1 (fr)
CN (2) CN1832962A (fr)
AR (1) AR045327A1 (fr)
AT (1) ATE394424T1 (fr)
AU (1) AU2004262570B2 (fr)
BR (1) BRPI0413437B1 (fr)
CA (1) CA2534224C (fr)
CO (1) CO5660271A2 (fr)
CY (1) CY1108775T1 (fr)
DE (1) DE602004013599D1 (fr)
DK (1) DK1654280T3 (fr)
EC (1) ECSP066352A (fr)
ES (1) ES2307039T3 (fr)
GB (1) GB0318682D0 (fr)
HR (1) HRP20080350T3 (fr)
IL (1) IL173272A (fr)
IS (1) IS2894B (fr)
MA (1) MA27982A1 (fr)
MX (1) MXPA06001525A (fr)
MY (1) MY141731A (fr)
NO (1) NO338367B1 (fr)
NZ (1) NZ544961A (fr)
PE (2) PE20050356A1 (fr)
PL (1) PL1654280T3 (fr)
PT (1) PT1654280E (fr)
RU (1) RU2360921C2 (fr)
SI (1) SI1654280T1 (fr)
TN (1) TNSN06045A1 (fr)
TW (1) TWI345570B (fr)
WO (1) WO2005014624A2 (fr)
ZA (1) ZA200600584B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101500528B1 (ko) * 2007-12-03 2015-03-09 이탈파마코 에스.피.에이. 새로운 비-선택적 소마토스타틴 유사체
EP2067786A1 (fr) 2007-12-07 2009-06-10 ITALFARMACO S.p.A. Nouveaux analogues non sélectifs de somatostatine
DK2343051T3 (da) 2010-01-05 2014-10-27 Nat Univ Dong Hwa Anti-cancer formulering
CN103467575B (zh) * 2013-08-22 2016-03-02 深圳翰宇药业股份有限公司 一种帕西瑞肽的制备方法
CN103641894B (zh) * 2013-12-06 2015-10-28 深圳翰宇药业股份有限公司 一种治疗库欣病的多肽药物的制备方法
WO2016097962A1 (fr) * 2014-12-19 2016-06-23 Auro Peptides Ltd Procédé de préparation de pasiréotide
CN106188231B (zh) * 2015-05-25 2021-10-22 中国医学科学院药物研究所 帕西瑞肽五肽中间体的合成与应用
CN114621326B (zh) * 2020-12-10 2023-12-26 武汉武药科技有限公司 门冬氨酸帕瑞肽及其中间体和其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3303345A1 (de) * 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Cyclische peptide mit somatostatin-wirkung
EP0255224A3 (fr) 1986-06-30 1990-04-18 Merck & Co. Inc. Analogues cycliques et pontés cycliques du somatostatin utilisable comme médicaments analgésiques
US5811512A (en) 1991-08-22 1998-09-22 The Trustees Of The University Of Pennsylvania Non-peptide peptidomimetics and related cyclic hexapeptides
WO1995000553A1 (fr) * 1993-06-23 1995-01-05 Diatech, Inc. Peptides radiomarques derives de la somatostatine et utilises dans des procedes d'imagerie et therapeutiques
US5770687A (en) 1995-06-07 1998-06-23 Peptor Limited Comformationally constrained backbone cyclized somatostatin analogs
GB9513224D0 (en) * 1995-06-29 1995-09-06 Sandoz Ltd Organic compounds
US6355613B1 (en) 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
GB0018891D0 (en) * 2000-08-01 2000-09-20 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
CN102127155A (zh) 2011-07-20
KR101136633B1 (ko) 2012-04-18
KR20060070541A (ko) 2006-06-23
CA2534224A1 (fr) 2005-02-17
IS2894B (is) 2014-09-15
NO20061125L (no) 2006-05-08
MXPA06001525A (es) 2006-05-15
WO2005014624A3 (fr) 2005-09-22
ZA200600584B (en) 2006-12-27
HK1090065A1 (en) 2006-12-15
AU2004262570B2 (en) 2008-06-19
IL173272A (en) 2012-03-29
GB0318682D0 (en) 2003-09-10
PE20091210A1 (es) 2009-09-07
US20060258838A1 (en) 2006-11-16
TWI345570B (en) 2011-07-21
DK1654280T3 (da) 2008-09-29
AR045327A1 (es) 2005-10-26
DE602004013599D1 (de) 2008-06-19
EP1654280B1 (fr) 2008-05-07
EP1654280B8 (fr) 2008-08-13
CO5660271A2 (es) 2006-07-31
US7615609B2 (en) 2009-11-10
EP1654280A2 (fr) 2006-05-10
ECSP066352A (es) 2006-08-30
IS8338A (is) 2006-03-02
HRP20080350T3 (en) 2008-08-31
CN102127155B (zh) 2013-11-27
MY141731A (en) 2010-06-15
SI1654280T1 (sl) 2008-10-31
PE20050356A1 (es) 2005-06-17
WO2005014624A2 (fr) 2005-02-17
TW200524955A (en) 2005-08-01
NO338367B1 (no) 2016-08-15
RU2360921C2 (ru) 2009-07-10
JP4580928B2 (ja) 2010-11-17
RU2006106721A (ru) 2007-09-20
AU2004262570A1 (en) 2005-02-17
IL173272A0 (en) 2006-06-11
CA2534224C (fr) 2012-03-27
ES2307039T3 (es) 2008-11-16
ATE394424T1 (de) 2008-05-15
NZ544961A (en) 2008-08-29
BRPI0413437B1 (pt) 2017-12-12
TNSN06045A1 (en) 2007-10-03
PL1654280T3 (pl) 2008-10-31
JP2007526899A (ja) 2007-09-20
BRPI0413437A (pt) 2006-10-10
CN1832962A (zh) 2006-09-13
PT1654280E (pt) 2008-08-18
CY1108775T1 (el) 2014-04-09

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