MA28224A1 - Nitro-oxyderives de medicaments contre l'hypertension. - Google Patents

Nitro-oxyderives de medicaments contre l'hypertension.

Info

Publication number
MA28224A1
MA28224A1 MA29085A MA29085A MA28224A1 MA 28224 A1 MA28224 A1 MA 28224A1 MA 29085 A MA29085 A MA 29085A MA 29085 A MA29085 A MA 29085A MA 28224 A1 MA28224 A1 MA 28224A1
Authority
MA
Morocco
Prior art keywords
nitro
oxidine
drugs against
against hypertension
hypertension
Prior art date
Application number
MA29085A
Other languages
English (en)
Inventor
Soldato Piero Del
Francesca Benedini
Ennio Ongini
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Publication of MA28224A1 publication Critical patent/MA28224A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention concerne des nitro-oxydérivés bêta-bloquants de formule générale (I) A-(Y-ONO2)s, y compris les énantiomères, diastéréoisomères et sels pharmaceutiquement acceptables correspondants, des compositions pharmaceutiques les renfermant, et leur utilisation pour le traitement de l'hypertension, des maladies cardio-vasculaires, du glaucome, de la migraine et des maladies vasculaires.
MA29085A 2003-12-02 2006-06-07 Nitro-oxyderives de medicaments contre l'hypertension. MA28224A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03104485 2003-12-02

Publications (1)

Publication Number Publication Date
MA28224A1 true MA28224A1 (fr) 2006-10-02

Family

ID=34639310

Family Applications (1)

Application Number Title Priority Date Filing Date
MA29085A MA28224A1 (fr) 2003-12-02 2006-06-07 Nitro-oxyderives de medicaments contre l'hypertension.

Country Status (21)

Country Link
US (1) US20070060586A1 (fr)
EP (1) EP1748994B1 (fr)
JP (1) JP2007513113A (fr)
KR (1) KR20060120164A (fr)
CN (1) CN1906182A (fr)
AP (1) AP2006003622A0 (fr)
AR (1) AR047264A1 (fr)
AT (1) ATE423107T1 (fr)
AU (1) AU2004295105A1 (fr)
BR (1) BRPI0417182A (fr)
CA (1) CA2548127A1 (fr)
DE (1) DE602004019579D1 (fr)
EA (1) EA200600891A1 (fr)
EC (1) ECSP066590A (fr)
ES (1) ES2320002T3 (fr)
IL (1) IL176061A0 (fr)
MA (1) MA28224A1 (fr)
NO (1) NO20062527L (fr)
TN (1) TNSN06151A1 (fr)
WO (1) WO2005054218A1 (fr)
ZA (1) ZA200604463B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE437637T1 (de) 2001-05-02 2009-08-15 Nitromed Inc Nitrosiertes und nitrosyliertes nebivolol und seine metaboliten, zusammensetzungen und anwendungsverfahren
WO2007090733A1 (fr) * 2006-02-06 2007-08-16 Nicox S.A. Dérivés nitrooxy utilisables comme agonistes des récepteurs alpha 2 adrénergiques
US7799784B2 (en) 2006-02-06 2010-09-21 Nicox S.A. Quinoxaline derivatives of alpha-2 adrenergic agonists
US20230131943A1 (en) 2020-03-24 2023-04-27 Burnet Micheal W Anti-infective and anti-viral compounds and compositions
CN118146175A (zh) * 2024-02-07 2024-06-07 广州楷石生物科技有限公司 右旋噻吗洛尔衍生物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3443998A1 (de) * 1984-12-01 1986-06-05 Boehringer Mannheim Gmbh, 6800 Mannheim Amino-propanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
ES2065291B1 (es) * 1993-07-30 1995-10-01 Prodesfarma Sa "nitrato esteres de 1-ariloxi-3-alquilamino-2-propanoles, utilizacion y composicion farmaceutica correspondiente"
IT1295694B1 (it) * 1996-11-14 1999-05-27 Nicox Sa Nitrossi derivati per la preparazione di medicamenti ad attivita antitrombinica
IT1311923B1 (it) * 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.
IT1314184B1 (it) * 1999-08-12 2002-12-06 Nicox Sa Composizioni farmaceutiche per la terapia di condizioni di stressossidativo

Also Published As

Publication number Publication date
ZA200604463B (en) 2007-04-25
JP2007513113A (ja) 2007-05-24
NO20062527L (no) 2006-06-30
EA200600891A1 (ru) 2006-10-27
CA2548127A1 (fr) 2005-06-16
AR047264A1 (es) 2006-01-11
BRPI0417182A (pt) 2007-03-06
IL176061A0 (en) 2006-10-05
KR20060120164A (ko) 2006-11-24
ECSP066590A (es) 2006-10-17
AP2006003622A0 (en) 2006-06-30
ATE423107T1 (de) 2009-03-15
US20070060586A1 (en) 2007-03-15
CN1906182A (zh) 2007-01-31
ES2320002T3 (es) 2009-05-18
EP1748994B1 (fr) 2009-02-18
DE602004019579D1 (de) 2009-04-02
TNSN06151A1 (en) 2007-11-15
AU2004295105A1 (en) 2005-06-16
EP1748994A1 (fr) 2007-02-07
WO2005054218A1 (fr) 2005-06-16

Similar Documents

Publication Publication Date Title
TNSN04246A1 (fr) Derives d'heteroarylamides benzocondenses de thienopyridines utiles comme agents therapeutiques, compositions pharmaceutiques les contenant et methodes pour leur utilisation
MA27801A1 (fr) Nouveaux composes heterocycliques pour le traitement des affections inflammatoires et allergiques, leur procede de preparation et compositions pharmaceutiques les contenant
TNSN05165A1 (fr) Derives de pyrrolopyrimidine
TN2009000471A1 (fr) Composes amino-heterocycliques
MXPA05010958A (es) Derivados indazol como inhibidores jnk.
DK1689721T3 (da) Aminopyrazolderivater som GSK-3-ihibitorer
TNSN08139A1 (fr) Composes therapeutiques
GEP20053600B (en) 3-(4-Amidopyrrol-2-Ylmethlidene)-2- Indolinone Derivatives as Protein Kinase Inhibitors
MA27311A1 (fr) Utilisation d'inhibiteurs de cetp et facultativement d'inhibiteurs de hmg-coa-reductase et/ou d'agents antihypertensifs
MA27316A1 (fr) Derives d'indoline-phenylsulfonamide
JP2005532372A5 (fr)
TNSN97044A1 (fr) Derives de quinoxalinedone, procedes et intermediaires pour leur preparation, et compositions pharmaceutiques les contenant.
MA29685B1 (fr) Composes spiroheterocycliques et leurs utilisations en tant qu'agents therapeutiques
TNSN07145A1 (fr) Derives de 2-amido-4-phenylthiazole, leur preparation et leur application en therapeutique
NO20050851L (no) Kaspase-inhibitorer og anvendelser derav
MA27093A1 (fr) Derives de sulfonamides, leur preparation et leur application comme medicaments.
TNSN00235A1 (fr) Derives d'heterocyclo-alkylsulfonylpyrazole nouveaux, procede pour leur preparation et compositions les contenant
NO20070837L (no) Pyrido-pyrido pyrimidinderivater, fremstilling derav samt terapeutisk anvendelse for behandling av cancer.
DK1641454T3 (da) Pyrazolo[3,4-B]pyridin-6-oner som GSK-3-hæmmere
US7183285B2 (en) Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
SE0102055D0 (sv) New Compounds
SG151336A1 (en) 1,3,4-oxadiazol-2-ones as ppar delta
KR20070036171A (ko) 선택적 노르아드레날린 재흡수 억제제와 ｐｄｅｖ 억제제의조합물
IL178167A0 (en) 1,3,4-oxadiazol-2-ones as ppar delta modulators
MA28224A1 (fr) Nitro-oxyderives de medicaments contre l'hypertension.