MA28796B1 - Procédé de production de dérivés de diarylcycloalkyle - Google Patents

Procédé de production de dérivés de diarylcycloalkyle

Info

Publication number
MA28796B1
MA28796B1 MA29674A MA29674A MA28796B1 MA 28796 B1 MA28796 B1 MA 28796B1 MA 29674 A MA29674 A MA 29674A MA 29674 A MA29674 A MA 29674A MA 28796 B1 MA28796 B1 MA 28796B1
Authority
MA
Morocco
Prior art keywords
producing
diarylcycloalkyl derivatives
diarylcycloalkyl
derivatives
producing diarylcycloalkyl
Prior art date
Application number
MA29674A
Other languages
English (en)
Inventor
Christophe Salagnad
Frank Zocher
Andreas Burgard
Bernd Junker
Rolf Hoerlein
Thomas Stuedemann
Claus-Juergen Maier
Jochen Hachtel
Wolfgang Holla
Christoph Tappertzhofen
Berndt Kulitzscher
Stephane Mutti
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of MA28796B1 publication Critical patent/MA28796B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/03—Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/62—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems having two or more ring systems containing condensed 1,3-oxazole rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/14—Nitrogen or oxygen as hetero atom and at least one other diverse hetero ring atom in the same ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MA29674A 2004-08-23 2007-02-08 Procédé de production de dérivés de diarylcycloalkyle MA28796B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004040736A DE102004040736B4 (de) 2004-08-23 2004-08-23 Verfahren zur Herstellung von Diarylcycloalkylderivaten

Publications (1)

Publication Number Publication Date
MA28796B1 true MA28796B1 (fr) 2007-08-01

Family

ID=35745474

Family Applications (1)

Application Number Title Priority Date Filing Date
MA29674A MA28796B1 (fr) 2004-08-23 2007-02-08 Procédé de production de dérivés de diarylcycloalkyle

Country Status (27)

Country Link
US (2) US7803950B2 (fr)
EP (1) EP1786913B1 (fr)
JP (1) JP4991543B2 (fr)
KR (1) KR20070048741A (fr)
CN (1) CN101014714B (fr)
AR (1) AR053760A1 (fr)
AT (1) ATE520785T1 (fr)
AU (1) AU2005276642B2 (fr)
BR (1) BRPI0514000A (fr)
CA (1) CA2578342A1 (fr)
CY (1) CY1112080T1 (fr)
DE (1) DE102004040736B4 (fr)
DK (1) DK1786913T3 (fr)
ES (1) ES2371762T3 (fr)
IL (1) IL181339A0 (fr)
MA (1) MA28796B1 (fr)
MX (1) MX2007001872A (fr)
NO (1) NO20071316L (fr)
NZ (1) NZ553602A (fr)
PL (1) PL1786913T3 (fr)
PT (1) PT1786913E (fr)
RU (1) RU2414459C2 (fr)
SI (1) SI1786913T1 (fr)
TW (1) TW200621734A (fr)
UY (1) UY29082A1 (fr)
WO (1) WO2006021420A2 (fr)
ZA (1) ZA200700635B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050232972A1 (en) * 2004-04-15 2005-10-20 Steven Odrich Drug delivery via punctal plug
CN101381302B (zh) * 2007-09-07 2013-04-03 上海睿智化学研究有限公司 2-溴甲基-6-甲基苯甲酰氯/溴的制备方法
CA2706575C (fr) * 2008-01-25 2015-07-14 Xenoport, Inc. Resolution des enantiomeres de thiocarbonates d'acyloxyalkyle utilises dans la synthese de precurseurs de carbamates d'acyloxyalkyle

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5728899A (en) * 1995-03-27 1998-03-17 Hoechst Marion Roussel Inc. Preparation of cis-4-O-protected-2-cyclopentenol derivatives
HRP20040199A2 (en) * 2001-08-31 2005-04-30 Aventis Pharma Deutschland Gmbh Diaryl cycloalkyl derivatives, method for producing the same and the use thereof as ppar activators
US6884812B2 (en) * 2001-08-31 2005-04-26 Aventis Pharma Deutschland Gmbh Diarylcycloalkyl derivatives, processes for their preparation and their use as pharmaceuticals
ES2290439T3 (es) * 2002-02-25 2008-02-16 Eli Lilly And Company Moduladores del receptor activado del proliferador de peroxisomas.
US7094795B2 (en) * 2003-02-27 2006-08-22 Sanofi-Aventis Deutschland Gmbh Process for preparing the enantiomeric forms of cis-configured 1,3-cyclohexanediol derivatives
DE10308350B4 (de) * 2003-02-27 2006-06-01 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 1,3-Cyclohexandiol-Derivaten
DE10308353A1 (de) * 2003-02-27 2004-12-02 Aventis Pharma Deutschland Gmbh Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO2005040394A1 (fr) * 2003-10-22 2005-05-06 Rhodia Chimie Procede de fabrication de compose comprenant un groupement hydroxyle libre et un groupement hydroxyle protégé par une fonction ester par reaction enzymatique
DE102004038403B4 (de) * 2004-08-07 2006-08-31 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 3-Hydroxycyclohexancarbonsäure-Derivaten

Also Published As

Publication number Publication date
BRPI0514000A (pt) 2008-05-20
AU2005276642A1 (en) 2006-03-02
DE102004040736B4 (de) 2007-01-11
JP4991543B2 (ja) 2012-08-01
ZA200700635B (en) 2010-01-27
RU2007110644A (ru) 2008-09-27
UY29082A1 (es) 2006-03-31
TW200621734A (en) 2006-07-01
RU2414459C2 (ru) 2011-03-20
EP1786913A2 (fr) 2007-05-23
AU2005276642B2 (en) 2011-12-22
AR053760A1 (es) 2007-05-23
NO20071316L (no) 2007-05-22
PL1786913T3 (pl) 2012-01-31
MX2007001872A (es) 2007-04-24
PT1786913E (pt) 2011-10-31
ATE520785T1 (de) 2011-09-15
SI1786913T1 (sl) 2011-12-30
CN101014714A (zh) 2007-08-08
WO2006021420A3 (fr) 2006-12-21
KR20070048741A (ko) 2007-05-09
EP1786913B1 (fr) 2011-08-17
DK1786913T3 (da) 2011-11-28
JP2008510761A (ja) 2008-04-10
IL181339A0 (en) 2007-07-04
DE102004040736A1 (de) 2006-03-02
CN101014714B (zh) 2012-05-23
CY1112080T1 (el) 2015-11-04
US20080051583A1 (en) 2008-02-28
ES2371762T3 (es) 2012-01-09
WO2006021420B1 (fr) 2007-02-08
WO2006021420A2 (fr) 2006-03-02
US20070197614A1 (en) 2007-08-23
NZ553602A (en) 2010-04-30
US7803950B2 (en) 2010-09-28
CA2578342A1 (fr) 2006-03-02

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