BRPI0514000A - método para a produção de derivados de diarilcicloalquila - Google Patents
método para a produção de derivados de diarilcicloalquilaInfo
- Publication number
- BRPI0514000A BRPI0514000A BRPI0514000-5A BRPI0514000A BRPI0514000A BR PI0514000 A BRPI0514000 A BR PI0514000A BR PI0514000 A BRPI0514000 A BR PI0514000A BR PI0514000 A BRPI0514000 A BR PI0514000A
- Authority
- BR
- Brazil
- Prior art keywords
- production
- general formula
- diarylcycloalkyl derivatives
- diarylcycloalkyl
- derivatives
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000013067 intermediate product Substances 0.000 abstract 2
- DYLIWHYUXAJDOJ-OWOJBTEDSA-N (e)-4-(6-aminopurin-9-yl)but-2-en-1-ol Chemical compound NC1=NC=NC2=C1N=CN2C\C=C\CO DYLIWHYUXAJDOJ-OWOJBTEDSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/03—Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/62—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems having two or more ring systems containing condensed 1,3-oxazole rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/14—Nitrogen or oxygen as hetero atom and at least one other diverse hetero ring atom in the same ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
MéTODO PARA A PRODUçãO DE DERIVADOS DE DIARILCICLOALQUILA. A presente invenção refere-se a um método para produção de derivados de diarilcicloalquila da fórmula geral (I), em que os radicais têm os significados indicados. A invenção também refere-se aos novos produtos intermediários os quais são formados por meio do método inventivo, métodos para produção de produtos intermediários de compostos da fórmula geral (I), e um método para separação de misturas de isómero cis/trans de materiais de partida usados para a produção de compostos da fórmula geral (I).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004040736A DE102004040736B4 (de) | 2004-08-23 | 2004-08-23 | Verfahren zur Herstellung von Diarylcycloalkylderivaten |
| PCT/EP2005/009095 WO2006021420A2 (de) | 2004-08-23 | 2005-08-23 | Verfahren zur herstellung von diarylcycloalkylderivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0514000A true BRPI0514000A (pt) | 2008-05-20 |
Family
ID=35745474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0514000-5A BRPI0514000A (pt) | 2004-08-23 | 2005-08-23 | método para a produção de derivados de diarilcicloalquila |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US7803950B2 (pt) |
| EP (1) | EP1786913B1 (pt) |
| JP (1) | JP4991543B2 (pt) |
| KR (1) | KR20070048741A (pt) |
| CN (1) | CN101014714B (pt) |
| AR (1) | AR053760A1 (pt) |
| AT (1) | ATE520785T1 (pt) |
| AU (1) | AU2005276642B2 (pt) |
| BR (1) | BRPI0514000A (pt) |
| CA (1) | CA2578342A1 (pt) |
| CY (1) | CY1112080T1 (pt) |
| DE (1) | DE102004040736B4 (pt) |
| DK (1) | DK1786913T3 (pt) |
| ES (1) | ES2371762T3 (pt) |
| IL (1) | IL181339A0 (pt) |
| MA (1) | MA28796B1 (pt) |
| MX (1) | MX2007001872A (pt) |
| NO (1) | NO20071316L (pt) |
| NZ (1) | NZ553602A (pt) |
| PL (1) | PL1786913T3 (pt) |
| PT (1) | PT1786913E (pt) |
| RU (1) | RU2414459C2 (pt) |
| SI (1) | SI1786913T1 (pt) |
| TW (1) | TW200621734A (pt) |
| UY (1) | UY29082A1 (pt) |
| WO (1) | WO2006021420A2 (pt) |
| ZA (1) | ZA200700635B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050232972A1 (en) * | 2004-04-15 | 2005-10-20 | Steven Odrich | Drug delivery via punctal plug |
| CN101381302B (zh) * | 2007-09-07 | 2013-04-03 | 上海睿智化学研究有限公司 | 2-溴甲基-6-甲基苯甲酰氯/溴的制备方法 |
| EP2250143B1 (en) * | 2008-01-25 | 2016-04-20 | XenoPort, Inc. | Method for the enzymatic kinetic resolution of acyloxyalkyl thiocarbonates used for the synthesis of acyloxyalkyl carbamates |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5728899A (en) * | 1995-03-27 | 1998-03-17 | Hoechst Marion Roussel Inc. | Preparation of cis-4-O-protected-2-cyclopentenol derivatives |
| US6884812B2 (en) * | 2001-08-31 | 2005-04-26 | Aventis Pharma Deutschland Gmbh | Diarylcycloalkyl derivatives, processes for their preparation and their use as pharmaceuticals |
| JP4436129B2 (ja) * | 2001-08-31 | 2010-03-24 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | ジアリールシクロアルキル誘導体、その製造法及びｐｐａｒ−活性剤としてのその使用 |
| JP2005529077A (ja) * | 2002-02-25 | 2005-09-29 | イーライ・リリー・アンド・カンパニー | ペルオキシソーム増殖因子活性化受容体調節物質 |
| US7094795B2 (en) * | 2003-02-27 | 2006-08-22 | Sanofi-Aventis Deutschland Gmbh | Process for preparing the enantiomeric forms of cis-configured 1,3-cyclohexanediol derivatives |
| DE10308350B4 (de) * | 2003-02-27 | 2006-06-01 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 1,3-Cyclohexandiol-Derivaten |
| DE10308353A1 (de) * | 2003-02-27 | 2004-12-02 | Aventis Pharma Deutschland Gmbh | Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| EP1689874A1 (fr) * | 2003-10-22 | 2006-08-16 | Rhodia Chimie | Procede de fabrication de compose comprenant un groupement hydroxyle libre et un groupement hydroxyle protege par une fonction ester par reaction enzymatique |
| DE102004038403B4 (de) * | 2004-08-07 | 2006-08-31 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 3-Hydroxycyclohexancarbonsäure-Derivaten |
-
2004
- 2004-08-23 DE DE102004040736A patent/DE102004040736B4/de not_active Expired - Fee Related
-
2005
- 2005-08-22 AR ARP050103522A patent/AR053760A1/es not_active Application Discontinuation
- 2005-08-22 TW TW094128546A patent/TW200621734A/zh unknown
- 2005-08-23 PL PL05782434T patent/PL1786913T3/pl unknown
- 2005-08-23 DK DK05782434.4T patent/DK1786913T3/da active
- 2005-08-23 UY UY29082A patent/UY29082A1/es unknown
- 2005-08-23 CN CN200580028364XA patent/CN101014714B/zh not_active Expired - Fee Related
- 2005-08-23 JP JP2007528733A patent/JP4991543B2/ja not_active Expired - Fee Related
- 2005-08-23 NZ NZ553602A patent/NZ553602A/en not_active IP Right Cessation
- 2005-08-23 KR KR1020077004449A patent/KR20070048741A/ko not_active Ceased
- 2005-08-23 SI SI200531403T patent/SI1786913T1/sl unknown
- 2005-08-23 MX MX2007001872A patent/MX2007001872A/es active IP Right Grant
- 2005-08-23 PT PT05782434T patent/PT1786913E/pt unknown
- 2005-08-23 BR BRPI0514000-5A patent/BRPI0514000A/pt not_active IP Right Cessation
- 2005-08-23 CA CA002578342A patent/CA2578342A1/en not_active Abandoned
- 2005-08-23 EP EP05782434A patent/EP1786913B1/de not_active Expired - Lifetime
- 2005-08-23 AU AU2005276642A patent/AU2005276642B2/en not_active Ceased
- 2005-08-23 ES ES05782434T patent/ES2371762T3/es not_active Expired - Lifetime
- 2005-08-23 RU RU2007110644/04A patent/RU2414459C2/ru not_active IP Right Cessation
- 2005-08-23 AT AT05782434T patent/ATE520785T1/de active
- 2005-08-23 WO PCT/EP2005/009095 patent/WO2006021420A2/de not_active Ceased
-
2007
- 2007-01-23 ZA ZA200700635A patent/ZA200700635B/xx unknown
- 2007-02-08 MA MA29674A patent/MA28796B1/fr unknown
- 2007-02-14 IL IL181339A patent/IL181339A0/en unknown
- 2007-02-20 US US11/676,721 patent/US7803950B2/en not_active Expired - Fee Related
- 2007-03-12 NO NO20071316A patent/NO20071316L/no not_active Application Discontinuation
- 2007-10-31 US US11/930,244 patent/US20080051583A1/en not_active Abandoned
-
2011
- 2011-11-17 CY CY20111101110T patent/CY1112080T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06H | Technical and formal requirements: requirement cancelled [chapter 6.8 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014. |