MA29464B1 - Methode de preparation d'acides 1,6-dihydro-6-oxo-4-pyrimidinecarboxyliques eventuellement 2-substitues - Google Patents

Methode de preparation d'acides 1,6-dihydro-6-oxo-4-pyrimidinecarboxyliques eventuellement 2-substitues

Info

Publication number
MA29464B1
MA29464B1 MA30392A MA30392A MA29464B1 MA 29464 B1 MA29464 B1 MA 29464B1 MA 30392 A MA30392 A MA 30392A MA 30392 A MA30392 A MA 30392A MA 29464 B1 MA29464 B1 MA 29464B1
Authority
MA
Morocco
Prior art keywords
optionally
substituted
dihydro
oxo
preparation
Prior art date
Application number
MA30392A
Other languages
English (en)
Inventor
Rafael Shapiro
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of MA29464B1 publication Critical patent/MA29464B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

L'INVENTION CONCERNE UNE NOUVELLE MÉTHODE DE PRÉPARATION DE COMPOSÉS D'ACIDE 1,6-DIHYDRO-6-OXO-4-PYRIMIDINECARBOXYLIQUES ÉVENTUELLEMENT 2-SUBSTITUÉS DE FORMULE (I), DANS LAQUELLE R1 EST H OU UN FRAGMENT CARBONE ÉVENTUELLEMENT SUBSTITUÉ. L'INVENTION CONCERNE EN OUTRE LA MÉTHODE QUI COMPREND DES ÉTAPES SUPPLÉMENTAIRES DE PRÉPARATION D'ACIDES 4-PYRIMIDINE-CARBOXYLIQUES ÉVENTUELLEMENT SUBSTITUÉS ET D'ESTERS, UTILISANT LE COMPOSÉ DE FORMULE (I) COMME INTERMÉDIAIRE.
MA30392A 2005-05-06 2007-11-20 Methode de preparation d'acides 1,6-dihydro-6-oxo-4-pyrimidinecarboxyliques eventuellement 2-substitues MA29464B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67826405P 2005-05-06 2005-05-06

Publications (1)

Publication Number Publication Date
MA29464B1 true MA29464B1 (fr) 2008-05-02

Family

ID=36952291

Family Applications (1)

Application Number Title Priority Date Filing Date
MA30392A MA29464B1 (fr) 2005-05-06 2007-11-20 Methode de preparation d'acides 1,6-dihydro-6-oxo-4-pyrimidinecarboxyliques eventuellement 2-substitues

Country Status (25)

Country Link
US (2) US8198442B2 (fr)
EP (1) EP1877384B1 (fr)
JP (1) JP5161764B2 (fr)
KR (1) KR101379967B1 (fr)
CN (2) CN101171237B (fr)
AT (1) ATE506352T1 (fr)
AU (1) AU2006246374B2 (fr)
BR (1) BRPI0612475B8 (fr)
CA (1) CA2607934C (fr)
DE (1) DE602006021411D1 (fr)
DK (1) DK1877384T3 (fr)
EG (1) EG25480A (fr)
ES (1) ES2362005T3 (fr)
GE (1) GEP20105099B (fr)
IL (2) IL185885A (fr)
MA (1) MA29464B1 (fr)
ME (1) ME00498B (fr)
MX (1) MX2007013424A (fr)
NZ (1) NZ561399A (fr)
PL (1) PL1877384T3 (fr)
RS (2) RS51804B (fr)
TN (1) TNSN07403A1 (fr)
UA (1) UA92171C2 (fr)
WO (1) WO2006121648A2 (fr)
ZA (1) ZA200707975B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006247581B2 (en) * 2005-05-16 2011-10-20 E. I. Du Pont De Nemours And Company Method for preparing substituted pyrimidines
WO2007039522A2 (fr) * 2005-09-29 2007-04-12 Dsm Ip Assets B.V. Procede d'esterification d'un acide organique
CN101778829B (zh) * 2007-08-13 2013-07-31 陶氏益农公司 2-(2-氟-取代的苯基)-6-氨基-5-氯-4-嘧啶羧酸衍生物及其作为除草剂的用途
EP2327694B1 (fr) 2007-10-02 2013-07-24 Dow AgroSciences LLC Acides 4-amino-picoliniques substitués et leur utilisation en tant qu'herbicides
CA2720848C (fr) * 2008-04-18 2014-02-11 Dow Agrosciences Llc 2-(phenyl substitue)-6-hydroxy ou alcoxy-5-substitue-4-pyrimidine carboxylates et leur utilisation comme herbicides
TWI596088B (zh) * 2011-01-25 2017-08-21 陶氏農業科學公司 ４－胺基－６－（經取代的苯基）吡啶甲酸酯及６－胺基－２－（經取代的苯基）－４－嘧啶羧酸酯之芳烷酯以及其等作為除草劑之用途
EP2736897B1 (fr) * 2011-07-27 2015-11-25 Bayer Intellectual Property GmbH Acides picoliniques et acides pyrimidin-4-carboxyliques substitués, leur procédé de production et leur utilisation comme herbicides et régulateurs de croissance végétale
US9113629B2 (en) * 2013-03-15 2015-08-25 Dow Agrosciences Llc 4-amino-6-(4-substituted-phenyl)-picolinates and 6-amino-2-(4-substituted-phenyl)-pyrimidine-4-carboxylates and their use as herbicides
US9637505B2 (en) 2013-03-15 2017-05-02 Dow Agrosciences Llc 4-amino-6-(heterocyclic)picolinates and 6-amino-2-(heterocyclic)pyrimidine-4-carboxylates and their use as herbicides
KR20210125575A (ko) * 2013-03-15 2021-10-18 코르테바 애그리사이언스 엘엘씨 4-아미노-6-(헤테로시클릭)피콜리네이트 및 6-아미노-2-(헤테로시클릭)피리미딘-4-카르복실레이트 및 제초제로서의 그의 용도
TWI689252B (zh) 2014-09-15 2020-04-01 美商陶氏農業科學公司 源自於施用吡啶羧酸除草劑與乙醯乳酸合成酶（ａｌｓ）抑制劑的協同性雜草控制
TWI689251B (zh) 2014-09-15 2020-04-01 美商陶氏農業科學公司 源自於施用吡啶羧酸除草劑與合成生長素除草劑及/或生長素轉運抑制劑的協同性雜草控制
TWI685302B (zh) 2014-09-15 2020-02-21 美商陶氏農業科學公司 包含吡啶羧酸除草劑之安全的除草組成物
AR101863A1 (es) 2014-09-15 2017-01-18 Dow Agrosciences Llc Control sinérgico de malezas a partir de aplicaciones de herbicidas de ácido piridín carboxílico e inhibidores de fotosistema ii
TWI694770B (zh) 2014-09-15 2020-06-01 美商陶氏農業科學公司 包含吡啶羧酸除草劑之安全的除草組成物（二）
WO2026028053A2 (fr) 2024-07-27 2026-02-05 Assia Chemical Industries Ltd. Procédé de préparation de tovorafénib

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA207185A (fr) 1921-01-04 C. Wagner Virgil Rechaud a mets
JPS60100559A (ja) * 1983-11-05 1985-06-04 Morishita Seiyaku Kk ２−アニリノ−１，６−ジヒドロ−６−オキソ−５−ピリミジンカルボン酸誘導体，その製法及び該化合物を含有する抗アレルギ−剤
JPH0331267A (ja) 1989-06-28 1991-02-12 Morishita Pharmaceut Co Ltd ２―アニリノ―１，６―ジヒドロ―６―オキソ―４―ピリミジンカルボン酸誘導体
JPH0341071A (ja) 1989-07-06 1991-02-21 Morishita Pharmaceut Co Ltd １，６―ジヒドロ―６―オキソ―２―フェノキシアルキルチオ―５―ピリミジンカルボン酸類
DE3935277A1 (de) * 1989-10-24 1991-05-02 Hoechst Ag Sulfonierte heterocyclische carboxamide, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als herbizide oder wachstumsregulatoren
US5637618A (en) * 1990-06-01 1997-06-10 Bioresearch, Inc. Specific eatable taste modifiers
DE4029654A1 (de) 1990-09-19 1992-04-02 Hoechst Ag 2-phenyl-pyrimidine, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als fungizide
DE4131924A1 (de) * 1991-09-25 1993-07-08 Hoechst Ag Substituierte 4-alkoxypyrimidine, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel
DE4408404A1 (de) * 1994-03-12 1995-09-14 Huels Chemische Werke Ag Verfahren zur Herstellung von Chlorpyrimidinen
ATE245641T1 (de) * 1998-02-17 2003-08-15 Tularik Inc Antivirale pyrimidinderivate
US6281358B1 (en) 1999-04-15 2001-08-28 American Cyanamid Company Process for the preparation of substituted pyrimidines
DE60019606T2 (de) 1999-04-15 2005-08-18 Basf Ag Verfahren zur herstellung von substituierten pyrimidinen
AU2002258400A1 (en) 2001-02-16 2002-08-28 Tularik Inc. Methods of using pyrimidine-based antiviral agents
ATE440825T1 (de) * 2003-06-06 2009-09-15 Vertex Pharma Pyrimidin-derivate zur verwendung als modulatoren von atp-bindende kassette transportern
TWI355894B (en) 2003-12-19 2012-01-11 Du Pont Herbicidal pyrimidines
EP1849765A4 (fr) 2005-02-02 2010-05-05 Ajinomoto Kk Procédé servant à produire un composé de la pyrimidine
DE102005027150A1 (de) 2005-03-12 2006-09-28 Bayer Healthcare Ag Pyrimidincarbonsäure-Derivate und ihre Verwendung
AU2006247581B2 (en) * 2005-05-16 2011-10-20 E. I. Du Pont De Nemours And Company Method for preparing substituted pyrimidines

Also Published As

Publication number Publication date
IL185885A (en) 2012-10-31
AU2006246374B2 (en) 2012-03-29
PL1877384T3 (pl) 2011-09-30
US20120232271A1 (en) 2012-09-13
ATE506352T1 (de) 2011-05-15
CA2607934A1 (fr) 2006-11-16
WO2006121648A2 (fr) 2006-11-16
US20090043098A1 (en) 2009-02-12
AU2006246374A1 (en) 2006-11-16
KR20080006576A (ko) 2008-01-16
ZA200707975B (en) 2008-11-26
ME00498B (fr) 2011-10-10
CN101171237A (zh) 2008-04-30
CN102153516A (zh) 2011-08-17
RS51804B (sr) 2011-12-31
GEP20105099B (en) 2010-10-25
EG25480A (en) 2012-01-15
BRPI0612475B8 (pt) 2022-12-06
DE602006021411D1 (de) 2011-06-01
NZ561399A (en) 2009-11-27
IL222041A (en) 2016-10-31
EP1877384A2 (fr) 2008-01-16
UA92171C2 (ru) 2010-10-11
CN101171237B (zh) 2011-04-20
DK1877384T3 (da) 2011-08-15
TNSN07403A1 (en) 2009-03-17
KR101379967B1 (ko) 2014-04-01
JP5161764B2 (ja) 2013-03-13
US8198442B2 (en) 2012-06-12
ES2362005T3 (es) 2011-06-27
MX2007013424A (es) 2008-01-16
BRPI0612475B1 (pt) 2020-03-10
CA2607934C (fr) 2013-10-01
CN102153516B (zh) 2013-02-06
JP2008540414A (ja) 2008-11-20
EP1877384B1 (fr) 2011-04-20
RS20070434A (sr) 2009-01-22
WO2006121648A3 (fr) 2006-12-28
IL185885A0 (en) 2008-01-06
BRPI0612475A2 (pt) 2010-11-23

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