MA30766B1 - Formes de dosage pharmaceutiques orales anti-manipulation contenant un analgesique opioide - Google Patents
Formes de dosage pharmaceutiques orales anti-manipulation contenant un analgesique opioideInfo
- Publication number
- MA30766B1 MA30766B1 MA31733A MA31733A MA30766B1 MA 30766 B1 MA30766 B1 MA 30766B1 MA 31733 A MA31733 A MA 31733A MA 31733 A MA31733 A MA 31733A MA 30766 B1 MA30766 B1 MA 30766B1
- Authority
- MA
- Morocco
- Prior art keywords
- dosage forms
- pharmaceutical dosage
- opioid analgesic
- oral pharmaceutical
- forms anti
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/005—Coating of tablets or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B7/00—Mixing; Kneading
- B29B7/02—Mixing; Kneading non-continuous, with mechanical mixing or kneading devices, i.e. batch type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B7/00—Mixing; Kneading
- B29B7/80—Component parts, details or accessories; Auxiliary operations
- B29B7/88—Adding charges, i.e. additives
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
- B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
- B29C35/04—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould using liquids, gas or steam
- B29C35/045—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould using liquids, gas or steam using gas or flames
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
- B29C35/16—Cooling
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C37/00—Component parts, details, accessories or auxiliary operations, not covered by group B29C33/00 or B29C35/00
- B29C37/0025—Applying surface layers, e.g. coatings, decorative layers, printed layers, to articles during shaping, e.g. in-mould printing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/003—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor characterised by the choice of material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/02—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/32—Component parts, details or accessories; Auxiliary operations
- B29C43/52—Heating or cooling
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C71/00—After-treatment of articles without altering their shape; Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C71/00—After-treatment of articles without altering their shape; Apparatus therefor
- B29C71/009—After-treatment of articles without altering their shape; Apparatus therefor using gases without chemical reaction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
- B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
- B29C35/04—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould using liquids, gas or steam
- B29C35/045—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould using liquids, gas or steam using gas or flames
- B29C2035/046—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould using liquids, gas or steam using gas or flames dried air
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
- B29C35/16—Cooling
- B29C2035/1658—Cooling using gas
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2071/00—Use of polyethers, e.g. PEEK, i.e. polyether-etherketone or PEK, i.e. polyetherketone or derivatives thereof, as moulding material
- B29K2071/02—Polyalkylene oxides, e.g. PEO, i.e. polyethylene oxide, or derivatives thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/0005—Condition, form or state of moulded material or of the material to be shaped containing compounding ingredients
- B29K2105/0035—Medical or pharmaceutical agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/25—Solid
- B29K2105/251—Particles, powder or granules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
- B29K2995/0037—Other properties
- B29K2995/0088—Molecular weight
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mechanical Engineering (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Pain & Pain Management (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Thermal Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Plasma & Fusion (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
L'INVENTION CONCERNE DES FORMES POSOLOGIQUES PHARMACEUTIQUES, PAR EXEMPLE UNE FORME POSOLOGIQUE INVIOLABLE COMPRENANT UN ANALGÉSIQUE OPIOÏDE, ET LEURS PROCÉDÉS DE FABRICATION, LEURS UTILISATIONS ET DES PROCÉDÉS DE TRAITEMENT PAR CES FORMES POSOLOGIQUES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84024406P | 2006-08-25 | 2006-08-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA30766B1 true MA30766B1 (fr) | 2009-10-01 |
Family
ID=38754532
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA31733A MA30766B1 (fr) | 2006-08-25 | 2009-03-24 | Formes de dosage pharmaceutiques orales anti-manipulation contenant un analgesique opioide |
Country Status (41)
Families Citing this family (156)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030068375A1 (en) | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
| US20040253310A1 (en) | 2001-09-21 | 2004-12-16 | Gina Fischer | Morphine polymer release system |
| WO2003024429A1 (fr) | 2001-09-21 | 2003-03-27 | Egalet A/S | Systeme de liberation a base de polymere |
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| EP2218448B1 (fr) | 2002-12-13 | 2015-09-23 | Durect Corporation | Forme d'administration orale de medicaments comprenant un vehicule liquide de haute viscosite |
| US8877241B2 (en) | 2003-03-26 | 2014-11-04 | Egalet Ltd. | Morphine controlled release system |
| DE102004032051A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| DE102004020220A1 (de) * | 2004-04-22 | 2005-11-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
| DE102005005446A1 (de) * | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| DE10336400A1 (de) * | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
| US7201920B2 (en) | 2003-11-26 | 2007-04-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
| TWI365880B (en) | 2004-03-30 | 2012-06-11 | Euro Celtique Sa | Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone and oxycodone hydrochloride composition,pharmaceutical dosage form,sustained release oeal dosage form and pharmaceutically acceptable package having less than 25 pp |
| ES2653568T3 (es) | 2004-06-12 | 2018-02-07 | Collegium Pharmaceutical, Inc. | Formulaciones de fármacos para la prevención del abuso |
| DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| DE102004032103A1 (de) * | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| DK2767292T3 (en) | 2004-09-17 | 2016-12-19 | Durect Corp | RENEWABLE local anesthetic COMPOSITION CONTAINING SAIB |
| DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| NZ563846A (en) * | 2005-06-03 | 2010-03-26 | Egalet As | A drug delivery system for delivering active substances dispersed in a dispersion medium |
| US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
| SA07280459B1 (ar) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
| AU2007325918B2 (en) | 2006-11-03 | 2013-10-17 | Durect Corporation | Transdermal delivery systems comprising bupivacaine |
| DE102007011485A1 (de) | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
| US10512644B2 (en) | 2007-03-12 | 2019-12-24 | Inheris Pharmaceuticals, Inc. | Oligomer-opioid agonist conjugates |
| US8173666B2 (en) | 2007-03-12 | 2012-05-08 | Nektar Therapeutics | Oligomer-opioid agonist conjugates |
| US8821928B2 (en) | 2007-06-04 | 2014-09-02 | Egalet Ltd. | Controlled release pharmaceutical compositions for prolonged effect |
| US20080318994A1 (en) * | 2007-06-21 | 2008-12-25 | Endo Pharmaceuticals, Inc. | Method of Treating Pain Utilizing Controlled Release Oxymorphone Pharmaceutical Compositions and Instruction on Dosing for Renal Impairment |
| CN105534936B (zh) | 2007-08-13 | 2020-07-31 | Ohemo 生命科学股份有限公司 | 抗滥用药物、使用方法和制备方法 |
| EP2067471B1 (fr) | 2007-12-06 | 2018-02-14 | Durect Corporation | Formes orales de dosage pharmaceutique |
| TWI454288B (zh) | 2008-01-25 | 2014-10-01 | Gruenenthal Chemie | 藥物劑型 |
| WO2009114648A1 (fr) * | 2008-03-11 | 2009-09-17 | Depomed Inc. | Formes médicamenteuses à libération étendue de rétention gastrique comprenant des combinaisons d'un analgésique non opioïde et d'un analgésique opioïde |
| US8372432B2 (en) | 2008-03-11 | 2013-02-12 | Depomed, Inc. | Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic |
| ES2599031T3 (es) | 2008-05-09 | 2017-01-31 | Grünenthal GmbH | Proceso para la preparación de una formulación de polvo intermedia y una forma de dosificación solida final utilizando un paso de congelación por pulverización |
| CN102159193B (zh) * | 2008-09-18 | 2015-09-16 | 普渡制药公司 | 包含聚(ε-己内酯)的药物剂型 |
| US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
| EP2379111B1 (fr) | 2008-12-12 | 2013-03-20 | Paladin Labs Inc. | Formulations médicamenteuses narcotiques avec un potentiel d'abus réduit |
| NZ594207A (en) | 2009-02-06 | 2013-03-28 | Egalet Ltd | Immediate release composition resistant to abuse by intake of alcohol |
| ES2607209T3 (es) | 2009-02-06 | 2017-03-29 | Egalet Ltd. | Composiciones farmacéuticas resistentes al abuso |
| WO2010127100A1 (fr) * | 2009-05-01 | 2010-11-04 | Atley Pharmaceuticals, Inc. | Compositions comprenant un antihistaminique, un antitussif et un décongestionnant dans des formulations à libération prolongée |
| US20100280059A1 (en) * | 2009-05-01 | 2010-11-04 | Atley Pharmaceuticals, Inc. | Compositions comprising an antihistamine, antitussive and decongestant in extended release formulations |
| AU2010265213B2 (en) | 2009-06-24 | 2012-08-23 | Egalet Ltd. | Controlled release formulations |
| ES2534908T3 (es) | 2009-07-22 | 2015-04-30 | Grünenthal GmbH | Forma de dosificación de liberación controlada extruida por fusión en caliente |
| BR112012001466A2 (pt) | 2009-07-22 | 2020-08-11 | Grünenthal GmbH | forma de dosagem resistente à falsificação para opioides sensíveis à oxidação, seu processo de fabricação, e embalagem |
| US20110052685A1 (en) * | 2009-08-31 | 2011-03-03 | Depomed, Inc. | Gastric retentive pharmaceutical compositions for immediate and extended release of acetaminophen |
| EP3064064A1 (fr) | 2009-09-30 | 2016-09-07 | Acura Pharmaceuticals, Inc. | Procédés et compositions de dissuasion d'abus |
| US10668060B2 (en) | 2009-12-10 | 2020-06-02 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
| US9198861B2 (en) | 2009-12-22 | 2015-12-01 | Mallinckrodt Llc | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans |
| US8597681B2 (en) | 2009-12-22 | 2013-12-03 | Mallinckrodt Llc | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans |
| US9579285B2 (en) * | 2010-02-03 | 2017-02-28 | Gruenenthal Gmbh | Preparation of a powdery pharmaceutical composition by means of an extruder |
| SG184523A1 (en) | 2010-05-10 | 2012-11-29 | Euro Celtique Sa | Pharmaceutical compositions comprising hydromorphone and naloxone |
| MX340188B (es) | 2010-05-10 | 2016-06-30 | Euro-Celtique S A * | Elaboracion de granulos sin activos y tabletas que comprenden los mismos. |
| WO2011141490A1 (fr) | 2010-05-10 | 2011-11-17 | Euro-Celtique S.A. | Combinaison de granules chargés de principe actif et de principes actifs supplémentaires |
| AU2011267474B2 (en) | 2010-06-15 | 2016-05-26 | Grünenthal GmbH | Pharmaceutical combination for the treatment of pain |
| CA2808219C (fr) | 2010-09-02 | 2019-05-14 | Gruenenthal Gmbh | Forme pharmaceutique inviolable comportant un sel inorganique |
| WO2012028318A1 (fr) | 2010-09-02 | 2012-03-08 | Grünenthal GmbH | Forme pharmaceutique inviolable comportant un polymère anionique |
| EP2651399A2 (fr) | 2010-12-13 | 2013-10-23 | Purdue Pharma LP | Formes pharmaceutiques permettant une libération contrôlée |
| CN104856967A (zh) * | 2010-12-22 | 2015-08-26 | 普渡制药公司 | 包覆的抗篡改控制释放剂型 |
| PL2826467T3 (pl) | 2010-12-22 | 2018-01-31 | Purdue Pharma Lp | Zamknięte, zabezpieczone przed manipulowaniem formy dozowania o kontrolowanym uwalnianiu |
| PH12013501345A1 (en) | 2010-12-23 | 2022-10-24 | Purdue Pharma Lp | Tamper resistant solid oral dosage forms |
| CN103547259A (zh) * | 2011-03-25 | 2014-01-29 | 普渡制药公司 | 控制释放药物剂型 |
| US8858963B1 (en) | 2011-05-17 | 2014-10-14 | Mallinckrodt Llc | Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia |
| US8741885B1 (en) | 2011-05-17 | 2014-06-03 | Mallinckrodt Llc | Gastric retentive extended release pharmaceutical compositions |
| US9050335B1 (en) | 2011-05-17 | 2015-06-09 | Mallinckrodt Llc | Pharmaceutical compositions for extended release of oxycodone and acetaminophen resulting in a quick onset and prolonged period of analgesia |
| AT511581A1 (de) | 2011-05-26 | 2012-12-15 | G L Pharma Gmbh | Orale retardierende formulierung |
| JP6063462B2 (ja) | 2011-07-29 | 2017-01-18 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 即時薬剤放出を提供するタンパーレジスタント錠剤 |
| BR112014002022A2 (pt) | 2011-07-29 | 2017-02-21 | Gruenenthal Gmbh | comprimido resistente à violação proporcionando liberação de fármaco imediata |
| US20140341984A1 (en) * | 2011-09-16 | 2014-11-20 | Purdue Pharma L.P. | Tamper resistant pharmaceutical formulations |
| AU2012310251B2 (en) * | 2011-09-16 | 2016-01-21 | Purdue Pharma L.P. | Tamper resistant immediate release formulations |
| WO2013057570A2 (fr) * | 2011-10-18 | 2013-04-25 | Purdue Pharma L.P. | Formulations de polymère acrylique |
| KR20140096062A (ko) | 2011-11-17 | 2014-08-04 | 그뤼넨탈 게엠베하 | 약리학적 활성 성분, 오피오이드 길항제 및/또는 혐오제, 폴리알킬렌 옥사이드 및 음이온성 중합체를 포함하는 탬퍼-저항성 경구 약제학적 투여형 |
| US20150224097A1 (en) * | 2011-11-22 | 2015-08-13 | Watson Pharmaceuticals, Inc. | Immediate Release Abuse Deterrent Tablet |
| ES2603278T3 (es) * | 2011-12-09 | 2017-02-24 | Purdue Pharma Lp | Formas farmacéuticas de dosificación que comprenden poli (epsilon-caprolactona) y óxido de polietileno |
| BR112014019988A8 (pt) | 2012-02-28 | 2017-07-11 | Gruenenthal Gmbh | Forma de dosagem resistente a socamento compreendendo um composto farmacologicamente ativo e um polímero aniônico |
| WO2013158814A1 (fr) | 2012-04-18 | 2013-10-24 | Mallinckrodt Llc | Compositions pharmaceutiques dissuasives d'abus, à libération immédiate |
| LT2838512T (lt) | 2012-04-18 | 2018-11-12 | Grünenthal GmbH | Pažeidimui atspari ir dozės atpalaidavimo nuokrypiui atspari farmacinė vaisto forma |
| US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
| JP2015521988A (ja) * | 2012-07-06 | 2015-08-03 | イガレット・リミテッド | 制御放出用乱用防止性医薬組成物 |
| US9730885B2 (en) * | 2012-07-12 | 2017-08-15 | Mallinckrodt Llc | Extended release, abuse deterrent pharmaceutical compositions |
| CN104968333B (zh) | 2012-11-30 | 2018-07-10 | 阿库拉制药公司 | 活性药物成分的自调节释放 |
| PE20151301A1 (es) | 2013-02-05 | 2015-09-16 | Purdue Pharma Lp | Formulaciones farmaceuticas resistentes a la manipulacion indebida |
| BR112015021002B8 (pt) | 2013-03-15 | 2023-03-28 | Mallinckrodt Llc | Forma de dosagem sólida farmacêutica compreendendo um ingrediente farmacêutico ativo |
| US20140275038A1 (en) | 2013-03-15 | 2014-09-18 | Inspirion Delivery Technologies, Llc | Abuse deterrent compositions and methods of use |
| CA2905131A1 (fr) | 2013-03-15 | 2014-09-18 | Durect Corporation | Compositions ayant un agent de modification rheologique pour reduire une variabilite de dissolution |
| US10751287B2 (en) | 2013-03-15 | 2020-08-25 | Purdue Pharma L.P. | Tamper resistant pharmaceutical formulations |
| MX2015016254A (es) | 2013-05-29 | 2016-04-20 | Gruenenthal Gmbh | Forma de dosificacion resistente al uso indebido con perfil de liberacion bimodal. |
| AU2014273227B2 (en) * | 2013-05-29 | 2019-08-15 | Grunenthal Gmbh | Tamper-resistant dosage form containing one or more particles |
| AU2014289187B2 (en) | 2013-07-12 | 2019-07-11 | Grunenthal Gmbh | Tamper-resistant dosage form containing ethylene-vinyl acetate polymer |
| CA3042642A1 (fr) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Comprime extrude anti-abus a liberation immediate |
| JP6232135B2 (ja) | 2013-11-13 | 2017-11-15 | ユーロ−セルティーク エス.エイ. | 疼痛およびオピオイドによる腸機能障害症候群の治療のためのヒドロモルホンおよびナロキソン |
| HK1224189A1 (zh) | 2013-11-26 | 2017-08-18 | Grünenthal GmbH | 通过低温研磨制备粉状药物组合物 |
| WO2015095391A1 (fr) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Comprimé extrudé anti-abus à libération prolongée |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| CA2938699A1 (fr) | 2014-02-05 | 2015-08-13 | Kashiv Pharma Llc | Formulations de medicament resistantes aux abus avec protection integree contre le surdosage |
| JP6510628B2 (ja) | 2014-03-26 | 2019-05-15 | サン・ファーマ・アドバンスト・リサーチ・カンパニー・リミテッド | 乱用防止即時放出性被覆リザーバ固体剤形 |
| WO2015173195A1 (fr) | 2014-05-12 | 2015-11-19 | Grünenthal GmbH | Formulation pour capsule à libération immédiate résistant aux manipulations illicites comprenant du tapentadol |
| US9872835B2 (en) | 2014-05-26 | 2018-01-23 | Grünenthal GmbH | Multiparticles safeguarded against ethanolic dose-dumping |
| PL3164117T3 (pl) | 2014-07-03 | 2024-03-11 | SpecGx LLC | Preparaty zapewniające natychmiastowe uwalnianie i powstrzymujące przed nadużywaniem, zawierające polisacharydy inne niż celuloza |
| DK3169315T3 (da) | 2014-07-17 | 2020-08-10 | Pharmaceutical Manufacturing Res Services In | Væskefyldt doseringsform til forhindring af misbrug med øjeblikkelig frigivelse |
| US9132096B1 (en) | 2014-09-12 | 2015-09-15 | Alkermes Pharma Ireland Limited | Abuse resistant pharmaceutical compositions |
| US10729685B2 (en) | 2014-09-15 | 2020-08-04 | Ohemo Life Sciences Inc. | Orally administrable compositions and methods of deterring abuse by intranasal administration |
| AU2015336065A1 (en) | 2014-10-20 | 2017-05-04 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| JP5888387B1 (ja) * | 2014-10-22 | 2016-03-22 | ミツミ電機株式会社 | 電池保護回路及び電池保護装置、並びに電池パック |
| WO2016170093A1 (fr) | 2015-04-24 | 2016-10-27 | Grünenthal GmbH | Combinaison à dose fixe inaltérable présentant une libération rapide de deux médicaments de particules et d'une matrice |
| BR112017022856A2 (pt) | 2015-04-24 | 2018-07-17 | Gruenenthal Gmbh | combinação de dose fixa inviolável que proporciona rápida liberação de duas drogas a partir de partículas |
| US20160310428A1 (en) | 2015-04-24 | 2016-10-27 | Grunenthal Gmbh | Tamper-resistant fixed dose combination providing fast release of two drugs from different particles |
| WO2016170097A1 (fr) | 2015-04-24 | 2016-10-27 | Grünenthal GmbH | Forme galénique inviolable avec libération immédiate et résistance à l'extraction par solvant. |
| WO2017040607A1 (fr) | 2015-08-31 | 2017-03-09 | Acura Pharmaceuticals, Inc. | Procédés et compositions pour la libération auto-régulée d'un ingrédient pharmaceutique actif |
| CA2998259A1 (fr) | 2015-09-10 | 2017-03-16 | Grunenthal Gmbh | Protection contre un surdosage par voie orale a l'aide de formulations a liberation immediate dissuasives d'abus |
| CA3000418A1 (fr) * | 2015-09-30 | 2017-04-06 | Kashiv Pharma Llc | Formulation de medicament a liberation immediate de dissuasion d'abus et anti-surdose |
| US9943513B1 (en) | 2015-10-07 | 2018-04-17 | Banner Life Sciences Llc | Opioid abuse deterrent dosage forms |
| US20180303757A1 (en) * | 2015-10-23 | 2018-10-25 | Kashiv Pharma Llc | Enhanced abuse-deterrent formulations of oxycodone |
| JP2019504072A (ja) * | 2016-02-08 | 2019-02-14 | スペックジーエックス エルエルシー | 徐放性及び濫用抑止特性を有するグルコマンナン含有医薬組成物 |
| JP6323846B2 (ja) * | 2016-04-07 | 2018-05-16 | 塩野義製薬株式会社 | オピオイドを含有する乱用防止製剤 |
| US20170296476A1 (en) | 2016-04-15 | 2017-10-19 | Grünenthal GmbH | Modified release abuse deterrent dosage forms |
| US10335405B1 (en) | 2016-05-04 | 2019-07-02 | Patheon Softgels, Inc. | Non-burst releasing pharmaceutical composition |
| US9737530B1 (en) | 2016-06-23 | 2017-08-22 | Collegium Pharmaceutical, Inc. | Process of making stable abuse-deterrent oral formulations |
| CN109475505A (zh) | 2016-07-06 | 2019-03-15 | 度瑞公司 | 具有药物组成物、屏障层及药物层的口服剂型 |
| AU2017307235A1 (en) | 2016-08-01 | 2019-01-31 | Grünenthal GmbH | Tamper resistant dosage form comprising an anionic polysaccharide |
| JP2019524761A (ja) | 2016-08-12 | 2019-09-05 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | エフェドリン及びその誘導体の改変防止製剤 |
| DE202016105585U1 (de) * | 2016-10-06 | 2017-01-23 | L.B. Bohle Maschinen + Verfahren Gmbh | Anlage zur Herstellung pharmazeutischer Tabletten |
| USD857156S1 (en) * | 2016-11-02 | 2019-08-20 | Innovative Water Care, Llc | Chemical tablet for aquatic systems |
| EP3554548A4 (fr) | 2016-12-19 | 2020-08-19 | The Regents of The University of California | Formulations de pilules non broyables |
| KR102051132B1 (ko) * | 2017-03-17 | 2019-12-02 | 주식회사 종근당 | 미라베그론 또는 이의 염을 포함하는 방출조절용 약제학적 조성물 |
| US10335375B2 (en) | 2017-05-30 | 2019-07-02 | Patheon Softgels, Inc. | Anti-overingestion abuse deterrent compositions |
| WO2019003062A1 (fr) * | 2017-06-29 | 2019-01-03 | Zenvision Pharma Llp | Forme galénique inviolable comprenant un agent pharmaceutiquement actif |
| EP4480495A3 (fr) * | 2017-07-10 | 2025-06-18 | Gel Cap Technologies, LLC | Capsule a double forme posologique pour libération et procédés, dispositifs et systèmes pour la produire |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| CA3078272A1 (fr) | 2017-10-13 | 2019-04-18 | Grunenthal Gmbh | Formes posologiques a liberation modifiee, dissuasives d'abus |
| CA3075292A1 (fr) * | 2017-10-20 | 2019-04-25 | Purdue Pharma L.P. | Formes posologiques pharmaceutiques |
| US12161754B2 (en) | 2017-12-20 | 2024-12-10 | Purdue Pharma L.P. | Abuse deterrent morphine sulfate dosage forms |
| US10624856B2 (en) | 2018-01-31 | 2020-04-21 | Dharma Laboratories LLC | Non-extractable oral solid dosage forms |
| TW202002957A (zh) | 2018-02-09 | 2020-01-16 | 德商歌林達有限公司 | 包含轉化抑制劑之麻黃素及其衍生物之抗損壞調配物 |
| EP3755785B1 (fr) | 2018-02-22 | 2026-03-18 | The Procter & Gamble Company | Procédés de fabrication d'articles de dose unitaire |
| CN115532201A (zh) * | 2018-06-21 | 2022-12-30 | 巴泰勒纪念研究所 | 增强型微通道或中通道装置及其增材制造方法 |
| CA3103440A1 (fr) | 2018-06-27 | 2020-01-02 | Clexio Biosciences Ltd. | Procede de traitement d'un trouble depressif majeur |
| BR112021004213A2 (pt) * | 2018-09-06 | 2021-05-25 | Fachhochschule Nordwestschweiz | forma de dosagem de formulação farmacêutica e método para preparar uma forma de dosagem de formulação farmacêutica |
| WO2020068510A1 (fr) | 2018-09-25 | 2020-04-02 | SpecGx LLC | Formes posologiques de capsules à libération immédiate anti-abus |
| WO2020070706A1 (fr) | 2018-10-05 | 2020-04-09 | Clexio Biosciences Ltd. | Régime posologique d'eskétamine pour le traitement d'un trouble dépressif majeur |
| WO2020070547A1 (fr) | 2018-10-05 | 2020-04-09 | Clexio Biosciences Ltd. | Régime posologique d'eskétamine pour le traitement d'un trouble dépressif majeur |
| WO2020075134A1 (fr) | 2018-10-11 | 2020-04-16 | Clexio Biosciences Ltd. | Eskétamine pour une utilisation dans le traitement d'un trouble dépressif majeur |
| WO2020079699A1 (fr) * | 2018-10-16 | 2020-04-23 | M.O Advanced Technologies (Moat) Ltd | Appareil et procédé permettant de prédire une propension de défauts de comprimé |
| CN111251521B (zh) * | 2018-12-03 | 2022-07-22 | 沈欣 | 液态珠丸的制造方法 |
| EP3698776A1 (fr) | 2019-02-19 | 2020-08-26 | Grünenthal GmbH | Forme posologique inviolable à libération immédiate et résistance à l'extraction par solvant |
| KR20220008824A (ko) | 2019-04-17 | 2022-01-21 | 컴퍼스 패쓰파인더 리미티드 | 실로시빈으로 불안 장애, 두통 장애 및 섭식 장애를 치료하는 방법 |
| AU2020347662B2 (en) * | 2019-09-13 | 2026-07-09 | Meiji Co., Ltd. | Solid food and solid milk |
| CN110946086B (zh) * | 2019-12-04 | 2023-05-12 | 北京猫猫狗狗科技有限公司 | 一种下料装置以及下料控制方法 |
| JP2023507926A (ja) | 2019-12-30 | 2023-02-28 | クレキシオ バイオサイエンシーズ エルティーディー. | 神経精神状態または神経学的状態を治療するためのエスケタミンを用いた投与計画 |
| WO2021137147A1 (fr) | 2019-12-30 | 2021-07-08 | Clexio Biosciences Ltd. | Régime posologique à base d'eskétamine pour le traitement d'un trouble dépressif majeur |
| WO2021146215A1 (fr) | 2020-01-13 | 2021-07-22 | Durect Corporation | Systèmes d'administration de médicament à libération prolongée avec impuretés réduites et procédés associés |
| USD943706S1 (en) * | 2020-06-10 | 2022-02-15 | Emily Florence Johns | Shower steamer |
| CA3203561A1 (fr) | 2021-01-12 | 2022-07-21 | Adrian Neil Verity | Systemes d'administration de medicament a liberation prolongee et procedes associes |
| CN114659554B (zh) * | 2022-03-01 | 2023-04-25 | 安徽农业大学 | 一种生物质颗粒机故障诊断方法 |
| US20250082587A1 (en) | 2023-09-12 | 2025-03-13 | Clexio Biosciences Ltd. | Method Of Treating Major Depressive Disorder |
Family Cites Families (318)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1485673A (en) | 1924-03-04 | Ministrator | ||
| US1468805A (en) | 1923-09-25 | Htabtin ereund | ||
| US1479293A (en) | 1924-01-01 | Hiabtor fbettlid | ||
| US636438A (en) | 1899-02-08 | 1899-11-07 | Charles H Lovejoy | Molder's chaplet. |
| US2654756A (en) | 1949-10-20 | 1953-10-06 | Mallinckrodt Chemical Works | Process of preparing codeinone, dihydrocodeinone, and dihydromorphinone |
| US2772270A (en) | 1954-10-21 | 1956-11-27 | M J Lewenstein | 14-hydroxymorphinone and 8, 14-dihydroxydihydromorphinone |
| US3096248A (en) | 1959-04-06 | 1963-07-02 | Rexall Drug & Chemical Company | Method of making an encapsulated tablet |
| US3097144A (en) | 1960-10-14 | 1963-07-09 | Upjohn Co | Heat-cured, polymeric, medicinal dosage film coatings containing a polyvinylpyrrolidone copolymer, polyethenoid acid, and polyethylene glycol |
| US3806603A (en) | 1969-10-13 | 1974-04-23 | W Gaunt | Pharmaceutical carriers of plasticized dried milled particles of hydrated cooked rice endosperm |
| US3885027A (en) | 1971-04-12 | 1975-05-20 | West Laboratories Inc | Orally administered drug composition for therapy in the treatment of narcotic drug addiction |
| US3966747A (en) | 1972-10-26 | 1976-06-29 | Bristol-Myers Company | 9-Hydroxy-6,7-benzomorphans |
| US3888027A (en) | 1973-07-30 | 1975-06-10 | Kennametal Inc | Arrangement for enhancing blade life |
| US3980766A (en) | 1973-08-13 | 1976-09-14 | West Laboratories, Inc. | Orally administered drug composition for therapy in the treatment of narcotic drug addiction |
| US3941865A (en) | 1973-12-10 | 1976-03-02 | Union Carbide Corporation | Extrusion of ethylene oxide resins |
| DE2530563C2 (de) | 1975-07-09 | 1986-07-24 | Bayer Ag, 5090 Leverkusen | Analgetische Arzneimittel mit vermindertem Mißbrauchspotential |
| GB1598458A (en) | 1977-04-01 | 1981-09-23 | Hoechst Uk Ltd | Tableting of microcapsules |
| US4175119A (en) | 1978-01-11 | 1979-11-20 | Porter Garry L | Composition and method to prevent accidental and intentional overdosage with psychoactive drugs |
| US4211681A (en) | 1978-08-16 | 1980-07-08 | Union Carbide Corporation | Poly(ethylene oxide) compositions |
| CA1146866A (fr) | 1979-07-05 | 1983-05-24 | Yamanouchi Pharmaceutical Co. Ltd. | Procede de production d'un compose pharmaceutique a liberation continue sous forme solide |
| DE3002664C2 (de) | 1980-01-25 | 1989-05-18 | Titmus Eurocon Kontaktlinsen Gmbh & Co Kg, 8750 Aschaffenburg | Weiche Kontaktlinse |
| IL70071A (en) | 1982-11-01 | 1987-12-31 | Merrell Dow Pharma | Multilayered sustained release pharmaceutical tablets having non-uniform distribution of active ingredient |
| US4501828A (en) | 1983-01-20 | 1985-02-26 | General Technology Applications,Inc. | Dissolving water soluble polymers |
| US4612008A (en) | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
| US4765989A (en) | 1983-05-11 | 1988-08-23 | Alza Corporation | Osmotic device for administering certain drugs |
| US4783337A (en) | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
| FR2557459B1 (fr) | 1984-01-02 | 1986-05-30 | Lhd Lab Hygiene Dietetique | Matrice inerte a base de polycaprolactone pour administration orale d'un medicament, et procede de preparation de la forme galenique comprenant cette matrice |
| US4599342A (en) | 1984-01-16 | 1986-07-08 | The Procter & Gamble Company | Pharmaceutical products providing enhanced analgesia |
| US4629621A (en) | 1984-07-23 | 1986-12-16 | Zetachron, Inc. | Erodible matrix for sustained release bioactive composition |
| AU592065B2 (en) | 1984-10-09 | 1990-01-04 | Dow Chemical Company, The | Sustained release dosage form based on highly plasticized cellulose ether gels |
| GB8507779D0 (en) | 1985-03-26 | 1985-05-01 | Fujisawa Pharmaceutical Co | Drug carrier |
| US4616644A (en) | 1985-06-14 | 1986-10-14 | Johnson & Johnson Products, Inc. | Hemostatic adhesive bandage |
| US4774092A (en) | 1985-06-24 | 1988-09-27 | Ici Australia Limited | Ingestible capsules |
| US4619988A (en) | 1985-06-26 | 1986-10-28 | Allied Corporation | High strength and high tensile modulus fibers or poly(ethylene oxide) |
| EP0328775B1 (fr) | 1985-06-28 | 1993-10-20 | Carrington Laboratories, Inc. | Procédé de préparation de produits d'aloès, produits et compositions fabriqués selon lesdits procédés |
| US4851521A (en) | 1985-07-08 | 1989-07-25 | Fidia, S.P.A. | Esters of hyaluronic acid |
| DE3689650T2 (de) | 1985-12-17 | 1994-05-26 | United States Surgical Corp | Bioresorbierbare Polymere von hohem Molekulargewicht und Implantate davon. |
| US4764378A (en) | 1986-02-10 | 1988-08-16 | Zetachron, Inc. | Buccal drug dosage form |
| US4713243A (en) | 1986-06-16 | 1987-12-15 | Johnson & Johnson Products, Inc. | Bioadhesive extruded film for intra-oral drug delivery and process |
| USRE33093E (en) | 1986-06-16 | 1989-10-17 | Johnson & Johnson Consumer Products, Inc. | Bioadhesive extruded film for intra-oral drug delivery and process |
| US4970075A (en) | 1986-07-18 | 1990-11-13 | Euroceltique, S.A. | Controlled release bases for pharmaceuticals |
| US4861598A (en) | 1986-07-18 | 1989-08-29 | Euroceltique, S.A. | Controlled release bases for pharmaceuticals |
| WO1988003408A1 (fr) | 1986-11-10 | 1988-05-19 | Biopure Corporation | Succedane du sang semi-synthetique extra pur |
| DE3643789A1 (de) | 1986-12-20 | 1988-06-30 | Bayer Ag | Thermoplastisch verarbeitbare, im wesentlichen lineare poly-(alpha)-aryl-olefin/polyurethan-blockcopolymere, verfahren zu deren herstellung und deren verwendung |
| US4892778A (en) | 1987-05-27 | 1990-01-09 | Alza Corporation | Juxtaposed laminated arrangement |
| US5019397A (en) | 1988-04-21 | 1991-05-28 | Alza Corporation | Aqueous emulsion for pharmaceutical dosage form |
| US5160743A (en) | 1988-04-28 | 1992-11-03 | Alza Corporation | Annealed composition for pharmaceutically acceptable drug |
| US5162504A (en) | 1988-06-03 | 1992-11-10 | Cytogen Corporation | Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients |
| US4960814A (en) | 1988-06-13 | 1990-10-02 | Eastman Kodak Company | Water-dispersible polymeric compositions |
| US5350741A (en) | 1988-07-30 | 1994-09-27 | Kanji Takada | Enteric formulations of physiologically active peptides and proteins |
| US5139790A (en) | 1988-10-14 | 1992-08-18 | Zetachron, Inc. | Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith |
| US5004601A (en) | 1988-10-14 | 1991-04-02 | Zetachron, Inc. | Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith |
| US5330766A (en) | 1989-01-06 | 1994-07-19 | F. H. Faulding & Co. Limited | Sustained release pharmaceutical composition |
| US5202128A (en) | 1989-01-06 | 1993-04-13 | F. H. Faulding & Co. Limited | Sustained release pharmaceutical composition |
| US5051222A (en) | 1989-09-01 | 1991-09-24 | Air Products And Chemicals, Inc. | Method for making extrudable polyvinyl alcohol compositions |
| EP0418596A3 (en) | 1989-09-21 | 1991-10-23 | American Cyanamid Company | Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form |
| US5169645A (en) | 1989-10-31 | 1992-12-08 | Duquesne University Of The Holy Ghost | Directly compressible granules having improved flow properties |
| US5200197A (en) | 1989-11-16 | 1993-04-06 | Alza Corporation | Contraceptive pill |
| GB8926612D0 (en) | 1989-11-24 | 1990-01-17 | Erba Farmitalia | Pharmaceutical compositions |
| FR2664851B1 (fr) | 1990-07-20 | 1992-10-16 | Oreal | Procede de compactage d'un melange pulverulent permettant d'obtenir un produit compact absorbant ou partiellement delitable et produit obtenu par ce procede. |
| SE9003904D0 (sv) | 1990-12-07 | 1990-12-07 | Astra Ab | Method for the manufacture of a pharmaceutical dosage form |
| US5273758A (en) * | 1991-03-18 | 1993-12-28 | Sandoz Ltd. | Directly compressible polyethylene oxide vehicle for preparing therapeutic dosage forms |
| WO1993006723A1 (fr) | 1991-10-04 | 1993-04-15 | Olin Corporation | Comprime fongicide |
| AU3070892A (en) | 1991-11-12 | 1993-06-15 | Nepera, Inc. | Adhesive hydrogels having extended use lives and process for the preparation of same |
| US5266331A (en) | 1991-11-27 | 1993-11-30 | Euroceltique, S.A. | Controlled release oxycodone compositions |
| US5656295A (en) | 1991-11-27 | 1997-08-12 | Euro-Celtique, S.A. | Controlled release oxycodone compositions |
| EP0615438B1 (fr) | 1991-12-05 | 1996-07-24 | Mallinckrodt Veterinary, Inc. | Matrice en glucide transparent servant la liberation prolongee d'un agent therapeutique |
| SG43179A1 (en) | 1991-12-18 | 1997-10-17 | Warner Lambert Co | A process for the prepatation of a solid dispersion |
| US5478577A (en) * | 1993-11-23 | 1995-12-26 | Euroceltique, S.A. | Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level |
| US5958459A (en) | 1991-12-24 | 1999-09-28 | Purdue Pharma L.P. | Opioid formulations having extended controlled released |
| US5273760A (en) | 1991-12-24 | 1993-12-28 | Euroceltigue, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| US5286493A (en) | 1992-01-27 | 1994-02-15 | Euroceltique, S.A. | Stabilized controlled release formulations having acrylic polymer coating |
| US5472712A (en) | 1991-12-24 | 1995-12-05 | Euroceltique, S.A. | Controlled-release formulations coated with aqueous dispersions of ethylcellulose |
| US5968551A (en) | 1991-12-24 | 1999-10-19 | Purdue Pharma L.P. | Orally administrable opioid formulations having extended duration of effect |
| US5681585A (en) | 1991-12-24 | 1997-10-28 | Euro-Celtique, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
| CA2117351C (fr) | 1992-01-13 | 1998-03-03 | Julian Belknap Lo | Methode de fabrication permettant d'accroitre la durete des comprimes |
| US5393528A (en) | 1992-05-07 | 1995-02-28 | Staab; Robert J. | Dissolvable device for contraception or delivery of medication |
| US5324351A (en) | 1992-08-13 | 1994-06-28 | Euroceltique | Aqueous dispersions of zein and preparation thereof |
| DE4227385A1 (de) | 1992-08-19 | 1994-02-24 | Kali Chemie Pharma Gmbh | Pankreatinmikropellets |
| KR100355130B1 (ko) | 1992-09-18 | 2003-01-30 | 야마노우치세이야쿠 가부시키가이샤 | 하이드로겔서방성정제 |
| FI101039B (fi) | 1992-10-09 | 1998-04-15 | Eeva Kristoffersson | Menetelmä lääkepellettien valmistamiseksi |
| AU679937B2 (en) | 1992-11-18 | 1997-07-17 | Johnson & Johnson Consumer Products, Inc. | Extrudable compositions for topical or transdermal drug delivery |
| FR2701152B1 (fr) | 1993-02-03 | 1995-03-10 | Digipress Sa | Procédé de fabrication d'un disque maître pour la réalisation d'une matrice de pressage notamment de disques optiques, matrice de pressage obtenue par ce procédé et disque optique obtenu à partir de cette matrice de pressage. |
| DE4309528C2 (de) | 1993-03-24 | 1998-05-20 | Doxa Gmbh | Folie oder Folienschlauch aus Casein, Verfahren zu deren Herstellung und deren Verwendung |
| NZ260408A (en) | 1993-05-10 | 1996-05-28 | Euro Celtique Sa | Controlled release preparation comprising tramadol |
| EP1442745A1 (fr) | 1993-10-07 | 2004-08-04 | Euro-Celtique | Compositions d'opioides pour administration orale ayant un effet prolongé |
| US5776146A (en) | 1993-10-20 | 1998-07-07 | Applied Medical Resources | Laparoscopic surgical clamp |
| KR100354702B1 (ko) | 1993-11-23 | 2002-12-28 | 유로-셀티크 소시에떼 아노뉨 | 약학조성물의제조방법및서방형조성물 |
| EP0654263B1 (fr) | 1993-11-23 | 2002-01-23 | Euro-Celtique S.A. | Procédé pour la préparation d'une composition pharmaceutique à libération prolongée |
| US5500227A (en) | 1993-11-23 | 1996-03-19 | Euro-Celtique, S.A. | Immediate release tablet cores of insoluble drugs having sustained-release coating |
| GB9401894D0 (en) | 1994-02-01 | 1994-03-30 | Rhone Poulenc Rorer Ltd | New compositions of matter |
| DE69530973T2 (de) | 1994-02-16 | 2004-05-19 | Abbott Laboratories, Abbott Park | Verfahren zur herstellung feinteiliger pharmazeutischer formulierungen |
| EP0744940B1 (fr) | 1994-02-17 | 1998-11-11 | MODI, Pankaj | Medicaments, vaccins et hormones incorpores dans des microspheres recouvertes de polylactides |
| US5458887A (en) | 1994-03-02 | 1995-10-17 | Andrx Pharmaceuticals, Inc. | Controlled release tablet formulation |
| DE69524214T3 (de) | 1994-05-06 | 2008-05-15 | Pfizer Inc. | Azithromycin enthaltende arzneiverabreichungsformen mit gesteuerter wirkstoffabgabe |
| AT403988B (de) | 1994-05-18 | 1998-07-27 | Lannacher Heilmittel | Festes orales retardpräparat |
| US5460826A (en) | 1994-06-27 | 1995-10-24 | Alza Corporation | Morphine therapy |
| US5914131A (en) | 1994-07-07 | 1999-06-22 | Alza Corporation | Hydromorphone therapy |
| DE4426245A1 (de) | 1994-07-23 | 1996-02-22 | Gruenenthal Gmbh | 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung |
| CA2130410C (fr) | 1994-08-18 | 2001-12-04 | Albert John Kerklaan | Plot de connexion retractable |
| SE502132C2 (sv) | 1994-08-23 | 1995-08-28 | Ecept Ab | Gravstensfäste |
| US6491945B1 (en) | 1994-09-16 | 2002-12-10 | Alza Corporation | Hydrocodone therapy |
| US5516808A (en) | 1994-10-27 | 1996-05-14 | Sawaya; Assad S. | Topical cellulose pharmaceutical formulation |
| US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| DE4446470A1 (de) | 1994-12-23 | 1996-06-27 | Basf Ag | Verfahren zur Herstellung von teilbaren Tabletten |
| US5585115A (en) | 1995-01-09 | 1996-12-17 | Edward H. Mendell Co., Inc. | Pharmaceutical excipient having improved compressability |
| US5945125A (en) | 1995-02-28 | 1999-08-31 | Temple University | Controlled release tablet |
| US5695781A (en) | 1995-03-01 | 1997-12-09 | Hallmark Pharmaceuticals, Inc. | Sustained release formulation containing three different types of polymers |
| ATE214596T1 (de) | 1995-04-14 | 2002-04-15 | Pharma Pass | Feste zusammensetzungen mit einem nicht-amorphem wirkstoff und polyäthylenoxyd |
| US6348469B1 (en) | 1995-04-14 | 2002-02-19 | Pharma Pass Llc | Solid compositions containing glipizide and polyethylene oxide |
| US6117453A (en) | 1995-04-14 | 2000-09-12 | Pharma Pass | Solid compositions containing polyethylene oxide and an active ingredient |
| US5654005A (en) | 1995-06-07 | 1997-08-05 | Andrx Pharmaceuticals, Inc. | Controlled release formulation having a preformed passageway |
| US5634702A (en) | 1995-09-27 | 1997-06-03 | Fistonich; Juraj | Hands free waste container having a closed cover that automatically opens when the container is moved outside its cabinet enclosure |
| GB9523752D0 (en) | 1995-11-21 | 1996-01-24 | Pfizer Ltd | Pharmaceutical formulations |
| DE19547766A1 (de) | 1995-12-20 | 1997-06-26 | Gruenenthal Gmbh | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol-verbindungen als pharmazeutische Wirkstoffe |
| US5783212A (en) | 1996-02-02 | 1998-07-21 | Temple University--of the Commonwealth System of Higher Education | Controlled release drug delivery system |
| JP2000517287A (ja) | 1996-03-11 | 2000-12-26 | イーライ・リリー・アンド・カンパニー | 物質乱用の処置方法 |
| PT914097E (pt) | 1996-03-12 | 2002-06-28 | Alza Corp | Composicao e forma de dosagem compreendendo antagonista de opioide |
| US6461644B1 (en) | 1996-03-25 | 2002-10-08 | Richard R. Jackson | Anesthetizing plastics, drug delivery plastics, and related medical products, systems and methods |
| US20020114838A1 (en) | 1996-04-05 | 2002-08-22 | Ayer Atul D. | Uniform drug delivery therapy |
| US6096339A (en) | 1997-04-04 | 2000-08-01 | Alza Corporation | Dosage form, process of making and using same |
| EP0894010B1 (fr) | 1996-04-10 | 2003-07-02 | Warner-Lambert Company LLC | Denaturants pour sels d'amine sympathomimetiques |
| US5886164A (en) | 1996-04-15 | 1999-03-23 | Zeneca Limited | DNA encoding enzymes related to ethylene biosynthesis and ripening from banana |
| US20040024006A1 (en) | 1996-05-06 | 2004-02-05 | Simon David Lew | Opioid pharmaceutical compositions |
| GB9611328D0 (en) | 1996-05-31 | 1996-08-07 | Zeneca Ltd | Pharmaceutical compositions |
| WO1997045091A2 (fr) | 1996-05-31 | 1997-12-04 | Euro-Celtique, S.A. | Formulations d'oxycodone a liberation prolongee sans effet sur l'etat alimente/a jeun |
| US5955096A (en) | 1996-06-25 | 1999-09-21 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients |
| PT1014941E (pt) | 1996-06-26 | 2009-07-08 | Univ Texas | Formulação farmacêutica extrudível por termofusão |
| US5730564A (en) | 1996-07-24 | 1998-03-24 | Illinois Tool Works Inc. | Cargo load supporting air bag having inflation indicating means, and method of determining proper inflation for spaced loads |
| DE19630236A1 (de) | 1996-07-26 | 1998-01-29 | Wolff Walsrode Ag | Biaxial gereckte, biologisch abbaubare und kompostierbare Wursthülle |
| US5869669A (en) | 1996-07-26 | 1999-02-09 | Penick Corporation | Preparation of 14-hydroxynormorphinones from normorphinone dienol acylates |
| BE1010353A5 (fr) | 1996-08-14 | 1998-06-02 | Boss Pharmaceuticals Ag | Procede pour la fabrication de produits pharmaceutiques, dispositif pour un tel procede et produits pharmaceutiques ainsi obtenus. |
| EP0950689B1 (fr) | 1996-11-05 | 2004-10-06 | NOVAMONT S.p.A. | Compositions polymériques biodégradables contenant de l'amidon et un polymère thermoplastique |
| US6919373B1 (en) | 1996-11-12 | 2005-07-19 | Alza Corporation | Methods and devices for providing prolonged drug therapy |
| US5948787A (en) | 1997-02-28 | 1999-09-07 | Alza Corporation | Compositions containing opiate analgesics |
| FR2761605B1 (fr) | 1997-04-07 | 2001-02-23 | Prographarm Lab | Forme pharmaceutique multiparticulaire, ses particules constitutives, procede et installation pour leur fabrication |
| US6635280B2 (en) | 1997-06-06 | 2003-10-21 | Depomed, Inc. | Extending the duration of drug release within the stomach during the fed mode |
| ATE302597T1 (de) | 1997-06-06 | 2005-09-15 | Depomed Inc | Im magen verweilende orale dosierungsformen von wasserlöslichen arzneistoffen mit kontrollierter freisetzung |
| IL121038A0 (en) | 1997-06-09 | 1997-11-20 | Technion Res & Dev Foundation | A pharmaceutical composition for lowering glucose level in blood |
| DE19724181A1 (de) | 1997-06-09 | 1998-12-10 | Bayer Ag | Multiple-unit-retard-Zubereitungen und Verfahren zu ihrer Herstellung |
| AU8532798A (en) | 1997-06-13 | 1998-12-30 | Roland Bodmeier | Compounds which delay the release of active substances |
| GB9713703D0 (en) | 1997-06-30 | 1997-09-03 | Johnson Matthey Plc | Preparation of opiates |
| US6306438B1 (en) | 1997-07-02 | 2001-10-23 | Euro-Celtique, S.A. | Stabilized sustained release tramadol formulations |
| WO1999016642A1 (fr) | 1997-09-26 | 1999-04-08 | Magna Interior Systems Inc. | Ensemble de fixation permettant d'assembler deux panneaux de structure interieurs |
| US6066339A (en) | 1997-10-17 | 2000-05-23 | Elan Corporation, Plc | Oral morphine multiparticulate formulation |
| DE19749724A1 (de) | 1997-11-11 | 1999-06-10 | Gruenenthal Gmbh | Verwendung einer Kombination aus Opioid und alpha-adrenergem Agonisten in Schmerzmitteln |
| DE59803468D1 (de) | 1997-11-28 | 2002-04-25 | Knoll Ag | Verfahren zur herstellung von lösungsmittelfreien nicht-kristallinen biologisch aktiven substanzen |
| DE19753534A1 (de) | 1997-12-03 | 1999-06-10 | Bayer Ag | Schnell kristallisierende, biologisch abbaubare Polyesteramide |
| GB9726365D0 (en) | 1997-12-13 | 1998-02-11 | Ciba Sc Holding Ag | Compounds |
| US6375957B1 (en) | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
| NZ504834A (en) | 1997-12-22 | 2001-12-21 | Schering Corp | Tricyclic amide molecular dispersion composition with enhanced bioavailability |
| TR200001942T2 (tr) | 1997-12-22 | 2000-11-21 | Euro-Celtique, S.A. | Opioid agonist/antagonist kombinasyonlar |
| CN1204890C (zh) | 1997-12-22 | 2005-06-08 | 欧罗赛铁克股份有限公司 | 防止阿片样物质滥用的方法 |
| DE19800698A1 (de) | 1998-01-10 | 1999-07-15 | Bayer Ag | Biologisch abbaubare Polyesteramide mit blockartig aufgebauten Polyester- und Polyamid-Segmenten |
| US6251430B1 (en) | 1998-02-04 | 2001-06-26 | Guohua Zhang | Water insoluble polymer based sustained release formulation |
| DE69918233T2 (de) | 1998-03-05 | 2005-02-24 | Mitsui Chemicals, Inc. | Polymilchsäure zusammensetzung und daraus hergestellter film |
| US6245357B1 (en) | 1998-03-06 | 2001-06-12 | Alza Corporation | Extended release dosage form |
| US6852337B2 (en) | 1998-04-09 | 2005-02-08 | Roche Diagnostics Gmbh | Carvedilol-galenics |
| DE19822979A1 (de) | 1998-05-25 | 1999-12-02 | Kalle Nalo Gmbh & Co Kg | Folie mit Stärke oder Stärkederivaten und Polyesterurethanen sowie Verfahren zu ihrer Herstellung |
| EP0974343B1 (fr) | 1998-07-22 | 2004-09-29 | Pharma Pass II LLC | Procédé de préparation d'une composition solide contentant du metoprolol |
| US6117452A (en) | 1998-08-12 | 2000-09-12 | Fuisz Technologies Ltd. | Fatty ester combinations |
| DE19838636A1 (de) | 1998-08-26 | 2000-03-02 | Basf Ag | Carotinoid-Formulierungen, enthaltend ein Gemisch aus beta-Carotin, Lycopin und Lutein |
| DE19855440A1 (de) | 1998-12-01 | 2000-06-08 | Basf Ag | Verfahren zum Herstellen fester Darreichungsformen mittels Schmelzextrusion |
| IE981008A1 (en) | 1998-12-02 | 2000-06-14 | Fuisz Internat Ltd | Microparticles Containing Water Insoluble Active Agents |
| EP1005863A1 (fr) | 1998-12-04 | 2000-06-07 | Synthelabo | Formes galeniques a liberation controlee contenant un hypnotique a activite courte ou un sel de ce compose |
| US6238697B1 (en) | 1998-12-21 | 2001-05-29 | Pharmalogix, Inc. | Methods and formulations for making bupropion hydrochloride tablets using direct compression |
| DE19901683B4 (de) | 1999-01-18 | 2005-07-21 | Grünenthal GmbH | Analgetikum mit kontrollierter Wirkstofffreisetzung |
| US6451604B1 (en) | 1999-06-04 | 2002-09-17 | Genesis Research & Development Corporation Limited | Compositions affecting programmed cell death and their use in the modification of forestry plant development |
| US20030118641A1 (en) | 2000-07-27 | 2003-06-26 | Roxane Laboratories, Inc. | Abuse-resistant sustained-release opioid formulation |
| US6403703B1 (en) | 1999-08-27 | 2002-06-11 | Rohm And Haas Company | Polymeric compositions from acrylic and unsaturated carboxyl monomers |
| DE19940944B4 (de) | 1999-08-31 | 2006-10-12 | Grünenthal GmbH | Retardierte, orale, pharmazeutische Darreichungsformen |
| CA2388560A1 (fr) | 1999-08-31 | 2001-03-08 | Grunenthal Gmbh | Forme d'administration a action retardee contenant du saccharinate de tramadol |
| US7807211B2 (en) | 1999-09-03 | 2010-10-05 | Advanced Cardiovascular Systems, Inc. | Thermal treatment of an implantable medical device |
| US6491683B1 (en) | 1999-09-07 | 2002-12-10 | Alza Corporation | Osmotic dosage form composed of an extruded polymer tube form |
| US6177567B1 (en) | 1999-10-15 | 2001-01-23 | Boehringer Ingelheim Chemicals, Inc. | Method for preparing oxycodone |
| DE19960494A1 (de) | 1999-12-15 | 2001-06-21 | Knoll Ag | Vorrichtung und Verfahren zum Herstellen von festen wirkstoffhaltigen Formen |
| WO2001045644A2 (fr) | 1999-12-23 | 2001-06-28 | Combe International Ltd. | Dispositif a resine de scellement et procede de fabrication |
| US6630086B1 (en) | 1999-12-30 | 2003-10-07 | Ethicon, Inc. | Gas assist molding of one-piece catheters |
| ECSP003314A (es) | 2000-01-11 | 2000-03-22 | Formulaciones medicamentosas retardadas que contienen una combinacion de un opioide y un - agonista | |
| US6680070B1 (en) | 2000-01-18 | 2004-01-20 | Albemarle Corporation | Particulate blends and compacted products formed therefrom, and the preparation thereof |
| SI2283842T1 (sl) | 2000-02-08 | 2015-07-31 | Euro-Celtique S.A. | Oralne formulacije opioidnih agonistov, varne pred zlorabo |
| US6277409B1 (en) | 2000-02-11 | 2001-08-21 | Mcneil-Ppc, Inc. | Protective coating for tablet |
| DE10015479A1 (de) | 2000-03-29 | 2001-10-11 | Basf Ag | Feste orale Darreichungsformen mit retardierter Wirkstofffreisetzung und hoher mechanischer Stabilität |
| US20010036943A1 (en) | 2000-04-07 | 2001-11-01 | Coe Jotham W. | Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines |
| DE10025947A1 (de) | 2000-05-26 | 2001-11-29 | Gruenenthal Gmbh | Wirkstoffkombination enthaltend Montirelin und eine Verbindung mit opioider Wirksamkeit |
| DE10025948A1 (de) | 2000-05-26 | 2001-11-29 | Gruenenthal Gmbh | Wirkstoffkombination |
| US20030194748A1 (en) | 2000-05-29 | 2003-10-16 | Tohru Nagasaki | Method for labeling with tritium |
| US6488962B1 (en) | 2000-06-20 | 2002-12-03 | Depomed, Inc. | Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms |
| DE10036400A1 (de) | 2000-07-26 | 2002-06-06 | Mitsubishi Polyester Film Gmbh | Weiße, biaxial orientierte Polyesterfolie |
| US20030086972A1 (en) * | 2000-08-09 | 2003-05-08 | Appel Leah E. | Hydrogel-driven drug dosage form |
| AU2001294902A1 (en) | 2000-09-28 | 2002-04-08 | The Dow Chemical Company | Polymer composite structures useful for controlled release systems |
| AU2002227383B2 (en) | 2000-10-30 | 2004-07-08 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
| US20020187192A1 (en) | 2001-04-30 | 2002-12-12 | Yatindra Joshi | Pharmaceutical composition which reduces or eliminates drug abuse potential |
| UA81224C2 (uk) | 2001-05-02 | 2007-12-25 | Euro Celtic S A | Дозована форма оксикодону та її застосування |
| EP1387673B1 (fr) | 2001-05-11 | 2010-12-29 | Endo Pharmaceuticals Inc. | Forme posologique d'opioides a liberation prolongee empechant la consommation abusive |
| ATE345112T1 (de) | 2001-05-11 | 2006-12-15 | Endo Pharmaceuticals Inc | Opioid enthaltende arzneiform gegen missbrauch |
| US20030064122A1 (en) | 2001-05-23 | 2003-04-03 | Endo Pharmaceuticals, Inc. | Abuse resistant pharmaceutical composition containing capsaicin |
| JP2004534056A (ja) | 2001-06-08 | 2004-11-11 | エンドー ファーマシューティカルズ, インコーポレイティド | アクリルポリマーを使用する制御放出投薬形態、およびそれを作製するためのプロセス |
| US7968119B2 (en) | 2001-06-26 | 2011-06-28 | Farrell John J | Tamper-proof narcotic delivery system |
| DK1404331T3 (da) | 2001-07-06 | 2008-01-28 | Penwest Pharmaceuticals Co | Sustained release-formuleringer af oxymorphon |
| US7144587B2 (en) | 2001-08-06 | 2006-12-05 | Euro-Celtique S.A. | Pharmaceutical formulation containing opioid agonist, opioid antagonist and bittering agent |
| AU2002319774B2 (en) | 2001-08-06 | 2005-04-21 | Euro-Celtique S.A. | Compositions and methods to prevent abuse of opioids |
| US7332182B2 (en) | 2001-08-06 | 2008-02-19 | Purdue Pharma L.P. | Pharmaceutical formulation containing opioid agonist, opioid antagonist and irritant |
| IL160217A0 (en) | 2001-08-06 | 2004-07-25 | Euro Celtique Sa | Compositions and methods to prevent abuse of opioids |
| US7157103B2 (en) | 2001-08-06 | 2007-01-02 | Euro-Celtique S.A. | Pharmaceutical formulation containing irritant |
| US20030068375A1 (en) | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
| AU2002321879A1 (en) | 2001-08-06 | 2003-03-03 | Thomas Gruber | Pharmaceutical formulation containing dye |
| US7141250B2 (en) | 2001-08-06 | 2006-11-28 | Euro-Celtique S.A. | Pharmaceutical formulation containing bittering agent |
| US7842307B2 (en) | 2001-08-06 | 2010-11-30 | Purdue Pharma L.P. | Pharmaceutical formulation containing opioid agonist, opioid antagonist and gelling agent |
| US20030069318A1 (en) | 2001-08-21 | 2003-04-10 | Wenbin Dang | Salts of analgesic substances in oil, and methods of making and using the same |
| US6691698B2 (en) | 2001-09-14 | 2004-02-17 | Fmc Technologies Inc. | Cooking oven having curved heat exchanger |
| US20030068276A1 (en) | 2001-09-17 | 2003-04-10 | Lyn Hughes | Dosage forms |
| US20030092724A1 (en) | 2001-09-18 | 2003-05-15 | Huaihung Kao | Combination sustained release-immediate release oral dosage forms with an opioid analgesic and a non-opioid analgesic |
| US20040253310A1 (en) * | 2001-09-21 | 2004-12-16 | Gina Fischer | Morphine polymer release system |
| WO2003024429A1 (fr) | 2001-09-21 | 2003-03-27 | Egalet A/S | Systeme de liberation a base de polymere |
| WO2003028698A2 (fr) | 2001-09-26 | 2003-04-10 | Steffens Klaus-Juergen | Procede et dispositif de production de granules comprenant au moins un principe actif pharmaceutique |
| US20030229158A1 (en) | 2001-09-28 | 2003-12-11 | Chen Jen Chi | Polymer composition and dosage forms comprising the same |
| US6982094B2 (en) | 2001-09-28 | 2006-01-03 | Mcneil-Ppc, Inc. | Systems, methods and apparatuses for manufacturing dosage forms |
| MXPA04002973A (es) | 2001-09-28 | 2005-06-20 | Johnson & Johnson | Formas de dosis de liberacion modificada. |
| PE20030527A1 (es) | 2001-10-24 | 2003-07-26 | Gruenenthal Chemie | Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen |
| US6723340B2 (en) | 2001-10-25 | 2004-04-20 | Depomed, Inc. | Optimal polymer mixtures for gastric retentive tablets |
| US20030152622A1 (en) | 2001-10-25 | 2003-08-14 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral diuretic |
| US20030104052A1 (en) | 2001-10-25 | 2003-06-05 | Bret Berner | Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract |
| US20030091630A1 (en) | 2001-10-25 | 2003-05-15 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data |
| CA2409552A1 (fr) | 2001-10-25 | 2003-04-25 | Depomed, Inc. | Forme posologique orale pouvant etre retenue dans l'estomac dont la liberation est limitee a la partie inferieure du tube digestif |
| US20040126428A1 (en) | 2001-11-02 | 2004-07-01 | Lyn Hughes | Pharmaceutical formulation including a resinate and an aversive agent |
| FR2833838B1 (fr) | 2001-12-21 | 2005-09-16 | Ellipse Pharmaceuticals | Procede de fabrication d'un comprime incluant un analgesique de type morphinique et comprime obtenu |
| US6938129B2 (en) | 2001-12-31 | 2005-08-30 | Intel Corporation | Distributed memory module cache |
| US20030161882A1 (en) | 2002-02-01 | 2003-08-28 | Waterman Kenneth C. | Osmotic delivery system |
| AU2003211146B2 (en) | 2002-02-21 | 2007-07-19 | Valeant International (Barbados) Srl | Controlled release dosage forms |
| GB0204772D0 (en) | 2002-02-28 | 2002-04-17 | Phoqus Ltd | Pharmaceutical dosage forms |
| US20030181882A1 (en) | 2002-03-22 | 2003-09-25 | Yasuo Toyoshima | Absorbent article |
| DE10217232B4 (de) | 2002-04-18 | 2004-08-19 | Ticona Gmbh | Verfahren zur Herstellung gefüllter Granulate aus Polyethylenen hohen bzw. ultrahohen Molekulargewichts |
| US20050106249A1 (en) | 2002-04-29 | 2005-05-19 | Stephen Hwang | Once-a-day, oral, controlled-release, oxycodone dosage forms |
| MXPA04010769A (es) | 2002-04-29 | 2005-07-05 | Alza Corp | Metodos y formas de dosificacion para suministro controlado de oxicodona. |
| AU2003234395B2 (en) | 2002-05-13 | 2008-01-24 | Endo Pharmaceuticals Inc. | Abuse-resistant opioid solid dosage form |
| WO2003097608A2 (fr) * | 2002-05-17 | 2003-11-27 | Jenken Biosciences, Inc. | Composes opioides et de type opioide et leurs utilisations |
| CA2487786A1 (fr) | 2002-05-31 | 2003-12-11 | Alza Corporation | Formes galeniques et compositions d'administration osmotique de diverses posologies de l'oxycodone |
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| DE10250083A1 (de) | 2002-06-17 | 2003-12-24 | Gruenenthal Gmbh | Gegen Missbrauch gesicherte Darreichungsform |
| WO2004004693A1 (fr) | 2002-07-05 | 2004-01-15 | Collgegium Pharmaceutical | Compositions pharmaceutiques empechant la consommation abusive d'opioides et d'autres drogues |
| US6853758B2 (en) | 2002-07-12 | 2005-02-08 | Optimer Photonics, Inc. | Scheme for controlling polarization in waveguides |
| US20040011806A1 (en) | 2002-07-17 | 2004-01-22 | Luciano Packaging Technologies, Inc. | Tablet filler device with star wheel |
| EP1526843A1 (fr) | 2002-07-25 | 2005-05-04 | Pharmacia Corporation | Procede de preparation de formes de dosage solides enrobees dans deux couches constituees d'un polymere insoluble dans l'eau et d'un faconneur de pores hydrosoluble |
| EP1537118A1 (fr) | 2002-08-15 | 2005-06-08 | Noramco, Inc. | Polymorhes d'oxycodone-hydrochlorure |
| JP4195447B2 (ja) | 2002-09-20 | 2008-12-10 | エフ エム シー コーポレーション | ミクロ結晶性セルロースを含有する化粧品用組成物 |
| JP5189242B2 (ja) | 2002-09-23 | 2013-04-24 | アルケルメス ファーマ アイルランド リミテッド | 乱用抵抗性の医薬組成物 |
| CA2500311A1 (fr) * | 2002-09-28 | 2004-04-08 | Mcneil-Ppc, Inc. | Formes de dosage a liberation modifiee |
| DE10250087A1 (de) | 2002-10-25 | 2004-05-06 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| DE10250084A1 (de) | 2002-10-25 | 2004-05-06 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| US8487002B2 (en) | 2002-10-25 | 2013-07-16 | Paladin Labs Inc. | Controlled-release compositions |
| DE10250088A1 (de) | 2002-10-25 | 2004-05-06 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| US20040110781A1 (en) | 2002-12-05 | 2004-06-10 | Harmon Troy M. | Pharmaceutical compositions containing indistinguishable drug components |
| US7093059B2 (en) | 2002-12-31 | 2006-08-15 | Intel Corporation | Read-write switching method for a memory controller |
| US20040185097A1 (en) | 2003-01-31 | 2004-09-23 | Glenmark Pharmaceuticals Ltd. | Controlled release modifying complex and pharmaceutical compositions thereof |
| JP5501553B2 (ja) | 2003-04-21 | 2014-05-21 | ユーロ−セルティーク エス.エイ. | 同時押出逆作用剤粒子を含有する改変防止剤形およびその製造工程 |
| BRPI0409945A (pt) | 2003-04-30 | 2006-04-25 | Purdue Pharma Lp | forma de dosagem resistente à alteração |
| EP1624859A4 (fr) | 2003-05-06 | 2010-06-23 | Bpsi Holdings Inc | Procede de preparation de compositions thermoformees contenant des liants de polymere acrylique, des posologies pharmaceutiques et leurs procedes de preparation |
| US20040241234A1 (en) | 2003-06-02 | 2004-12-02 | Alpharma, Inc. | Controlled release press-coated formulations of water-soluble active agents |
| US6864370B1 (en) | 2003-06-05 | 2005-03-08 | Zhaiwei Lin | Process for manufacturing oxycodone |
| TWI357815B (en) | 2003-06-27 | 2012-02-11 | Euro Celtique Sa | Multiparticulates |
| US20050031655A1 (en) | 2003-08-04 | 2005-02-10 | Schering Plough Healthcare Products, Inc. | Emulsion composition |
| DE10361596A1 (de) * | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| PT1842533E (pt) | 2003-08-06 | 2013-05-17 | Gruenenthal Gmbh | Forma de dosagem protegida contra abuso |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| DE102004020220A1 (de) | 2004-04-22 | 2005-11-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
| DE102004032051A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
| US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
| FR2858749B1 (fr) | 2003-08-14 | 2006-03-17 | Marcel Legris | Ruche permettant a l'abeille et a l'apiculteur de lutter radicalement contre le varroa jacobsoni tout en ameliorant la production de miel |
| DE602004032149D1 (de) * | 2003-09-26 | 2011-05-19 | Alza Corp | Oros-push-stick für die kontrollierte abgabe von wirkstoffen |
| WO2005034859A2 (fr) | 2003-10-03 | 2005-04-21 | Elite Laboratories Inc. | Formulations d'opioides a liberation prolongee et methode d'utilisation des formulations |
| KR20060108690A (ko) | 2003-10-29 | 2006-10-18 | 알자 코포레이션 | 1일 1회 경구용의 서방성 옥시코돈 제형 |
| US7201920B2 (en) | 2003-11-26 | 2007-04-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
| US20090233272A1 (en) | 2003-12-23 | 2009-09-17 | Autogenomics, Inc. | Multiplexed Nucleic Acid Analysis with High Specificity |
| AU2004314224A1 (en) | 2004-01-23 | 2005-08-04 | Antoine Sakellarides | Shock absorbing system for rowing boat oarlock |
| WO2005079752A2 (fr) | 2004-02-11 | 2005-09-01 | Rubicon Research Private Limited | Compositions pharmaceutiques a liberation controlee presentant une meilleure biodisponibilite |
| TWI350762B (en) | 2004-02-12 | 2011-10-21 | Euro Celtique Sa | Particulates |
| GB0403760D0 (en) | 2004-02-20 | 2004-03-24 | Clements Paul | Digging implement |
| TWI365880B (en) | 2004-03-30 | 2012-06-11 | Euro Celtique Sa | Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone and oxycodone hydrochloride composition,pharmaceutical dosage form,sustained release oeal dosage form and pharmaceutically acceptable package having less than 25 pp |
| DK1729730T3 (da) * | 2004-03-30 | 2009-03-23 | Euro Celtique Sa | Manipulationssikker doseringsform, der omfatter et adsorberende stof og et kontramiddel |
| PL1740156T3 (pl) * | 2004-04-22 | 2011-12-30 | Gruenenthal Gmbh | Sposób wytwarzania zabezpieczonej przed nadużyciem, stałej postaci aplikacyjnej |
| JP2006002884A (ja) * | 2004-06-18 | 2006-01-05 | Mitsubishi Plastics Ind Ltd | 連結具 |
| JP2006002886A (ja) * | 2004-06-18 | 2006-01-05 | Noriatsu Kojima | 排水管 |
| WO2006002286A1 (fr) * | 2004-06-22 | 2006-01-05 | Magna International Inc. | Moulage d'etancheite d'automobile |
| DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| PL1765298T3 (pl) | 2004-07-01 | 2013-01-31 | Gruenenthal Gmbh | Sposób wytwarzania stałej postaci dawkowania, która jest zabezpieczona przez nadużywaniem, wykorzystujący wytłaczarkę z przekładnią planetarną |
| AR053304A1 (es) | 2004-07-01 | 2007-05-02 | Gruenenthal Gmbh | Formas farmaceuticas orales protegidas frente al abuso con liberacion controlada de (1r,2r)-3-(3 dimetilamino-1-etil-2metil-propil)fenol y procedimiento para su produccion. |
| CA2572491A1 (fr) | 2004-07-01 | 2006-01-12 | Gruenenthal Gmbh | Forme posologique anti-abus pour administration par voie orale |
| GB0421149D0 (en) | 2004-09-23 | 2004-10-27 | Johnson Matthey Plc | Preparation of oxycodone |
| KR100905511B1 (ko) | 2005-01-28 | 2009-07-01 | 유로-셀띠끄 소시에떼 아노님 | 알코올 저항성 제형 |
| US20080274183A1 (en) | 2005-02-04 | 2008-11-06 | Phillip Michael Cook | Thermoplastic articles containing a medicament |
| DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| US7732427B2 (en) | 2005-03-31 | 2010-06-08 | University Of Delaware | Multifunctional and biologically active matrices from multicomponent polymeric solutions |
| BRPI0612802A2 (pt) | 2005-07-07 | 2010-11-30 | Farnam Co Inc | composições farmacêuticas de liberação sustentada para medicamentos extremamente hidrossolúveis |
| US20070092573A1 (en) | 2005-10-24 | 2007-04-26 | Laxminarayan Joshi | Stabilized extended release pharmaceutical compositions comprising a beta-adrenoreceptor antagonist |
| PL116330U1 (en) | 2005-10-31 | 2007-04-02 | Alza Corp | Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation |
| US20070117826A1 (en) | 2005-11-23 | 2007-05-24 | Forest Laboratories, Inc. | Pharmaceutical formulations comprising ibuprofen, oxycodone, and 14-hydroxycodeinone |
| US20090022798A1 (en) | 2007-07-20 | 2009-01-22 | Abbott Gmbh & Co. Kg | Formulations of nonopioid and confined opioid analgesics |
| US20070212414A1 (en) | 2006-03-08 | 2007-09-13 | Penwest Pharmaceuticals Co. | Ethanol-resistant sustained release formulations |
| US7778314B2 (en) | 2006-05-04 | 2010-08-17 | Texas Instruments Incorporated | Apparatus for and method of far-end crosstalk (FEXT) detection and estimation |
| SA07280459B1 (ar) * | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
| CN101652370A (zh) | 2006-12-04 | 2010-02-17 | 诺拉姆科有限公司 | 制备14-羟基可待因酮水平减少的羟考酮的方法 |
| EP2117518A2 (fr) | 2007-01-12 | 2009-11-18 | Wyeth a Corporation of the State of Delaware | Composition de type comprimé-dans-comprimé |
| EP2104493A2 (fr) | 2007-01-16 | 2009-09-30 | Egalet A/S | Utilisation (i) d'un polyglycol et (ii) d'une substance médicamenteuse active dans la préparation d'une composition pharmaceutique destinée (i) à réduire le risque de libération massive induite par l'alcool et/ou (ii) à réduire le risque de toxicomanie médicamenteuse |
| GB2450691A (en) | 2007-07-02 | 2009-01-07 | Alpharma Aps | One-pot preparation of oxycodone from thebaine |
| WO2009114648A1 (fr) | 2008-03-11 | 2009-09-17 | Depomed Inc. | Formes médicamenteuses à libération étendue de rétention gastrique comprenant des combinaisons d'un analgésique non opioïde et d'un analgésique opioïde |
| WO2009114646A2 (fr) | 2008-03-11 | 2009-09-17 | Robe Lighting Inc. | Luminaires à réseau de del |
| US8671872B2 (en) | 2009-02-16 | 2014-03-18 | Thomas Engineering Inc. | Production coater with exchangeable drums |
| ES2534908T3 (es) | 2009-07-22 | 2015-04-30 | Grünenthal GmbH | Forma de dosificación de liberación controlada extruida por fusión en caliente |
| US9492492B2 (en) * | 2010-12-17 | 2016-11-15 | Johnson & Johnson Consumer Inc. | Compositions comprising Lilium martagon extracts and uses thereof |
| PL2826467T3 (pl) * | 2010-12-22 | 2018-01-31 | Purdue Pharma Lp | Zamknięte, zabezpieczone przed manipulowaniem formy dozowania o kontrolowanym uwalnianiu |
| US9846413B2 (en) * | 2011-09-08 | 2017-12-19 | Fire Avert, Llc. | Safety shut-off device and method of use |
| US10764498B2 (en) * | 2017-03-22 | 2020-09-01 | Canon Kabushiki Kaisha | Image processing apparatus, method of controlling the same, and storage medium |
| US10764499B2 (en) * | 2017-06-16 | 2020-09-01 | Microsoft Technology Licensing, Llc | Motion blur detection |
| JP7335870B2 (ja) * | 2017-08-31 | 2023-08-30 | パーデュー、ファーマ、リミテッド、パートナーシップ | 医薬剤形 |
| CA3075292A1 (fr) * | 2017-10-20 | 2019-04-25 | Purdue Pharma L.P. | Formes posologiques pharmaceutiques |
-
2007
- 2007-08-22 SA SA7280459A patent/SA07280459B1/ar unknown
- 2007-08-23 JO JO2007345A patent/JO2858B1/en active
- 2007-08-24 CN CN201410024630.2A patent/CN103861111B/zh active Active
- 2007-08-24 BR BR122016004010A patent/BR122016004010B8/pt active IP Right Grant
- 2007-08-24 PL PL10192627T patent/PL2311459T3/pl unknown
- 2007-08-24 RS RS20110171A patent/RS51664B/sr unknown
- 2007-08-24 KR KR1020127021462A patent/KR101514388B1/ko active Active
- 2007-08-24 DK DK11156997.6T patent/DK2343071T3/da active
- 2007-08-24 ES ES11156997T patent/ES2411695T3/es active Active
- 2007-08-24 DE DE602007010974T patent/DE602007010974D1/de active Active
- 2007-08-24 RS RS20130223A patent/RS52793B/sr unknown
- 2007-08-24 EP EP09156838A patent/EP2080514B1/fr active Active
- 2007-08-24 SI SI200730982T patent/SI2292229T1/sl unknown
- 2007-08-24 UA UAA200902798A patent/UA96306C2/ru unknown
- 2007-08-24 PT PT111569976T patent/PT2343071E/pt unknown
- 2007-08-24 DE DE202007011825U patent/DE202007011825U1/de not_active Expired - Lifetime
- 2007-08-24 PL PL11157013T patent/PL2399580T3/pl unknown
- 2007-08-24 SI SI200731243T patent/SI2343071T1/sl unknown
- 2007-08-24 MY MYPI20124957 patent/MY153092A/en unknown
- 2007-08-24 CA CA2661573A patent/CA2661573C/fr active Active
- 2007-08-24 EA EA201171403A patent/EA023807B1/ru not_active IP Right Cessation
- 2007-08-24 PT PT09156838T patent/PT2080514E/pt unknown
- 2007-08-24 RS RS20120328A patent/RS52402B/sr unknown
- 2007-08-24 RS RSP-2009/0536A patent/RS51162B/sr unknown
- 2007-08-24 ME MEP-2011-27A patent/ME01339B/fr unknown
- 2007-08-24 EP EP07114982A patent/EP1897545B1/fr active Active
- 2007-08-24 ES ES09156832T patent/ES2357376T3/es active Active
- 2007-08-24 RS RS20120320A patent/RS52401B/sr unknown
- 2007-08-24 RS RS20130244A patent/RS52798B/sr unknown
- 2007-08-24 AT AT09156843T patent/ATE489954T1/de active
- 2007-08-24 EP EP11157013A patent/EP2399580B1/fr active Active
- 2007-08-24 CA CA2707204A patent/CA2707204C/fr active Active
- 2007-08-24 CN CN201210196551.0A patent/CN102688241B/zh active Active
- 2007-08-24 PL PL11156997T patent/PL2343071T3/pl unknown
- 2007-08-24 ES ES11157013T patent/ES2417335T3/es active Active
- 2007-08-24 PE PE2015000012A patent/PE20150340A1/es active IP Right Grant
- 2007-08-24 EP EP11157006.5A patent/EP2399579B9/fr active Active
- 2007-08-24 SI SI200730120T patent/SI1897545T1/sl unknown
- 2007-08-24 ME MEP-2011-79A patent/ME01187B/fr unknown
- 2007-08-24 ES ES10192644T patent/ES2388615T3/es active Active
- 2007-08-24 ME MEP-2009-348A patent/ME01064B/fr unknown
- 2007-08-24 CN CN201510599477.0A patent/CN105267170B/zh not_active Ceased
- 2007-08-24 PE PE2019000935A patent/PE20191048A1/es unknown
- 2007-08-24 RS RS20130265A patent/RS52813B/sr unknown
- 2007-08-24 PL PL10192644T patent/PL2292230T3/pl unknown
- 2007-08-24 SI SI200730512T patent/SI2082742T1/sl unknown
- 2007-08-24 CN CN201210196662.1A patent/CN102743355B/zh active Active
- 2007-08-24 ES ES10192627T patent/ES2390419T3/es active Active
- 2007-08-24 RS RS20120394A patent/RS52463B/sr unknown
- 2007-08-24 AR ARP070103759A patent/AR062511A1/es not_active Application Discontinuation
- 2007-08-24 KR KR1020157017047A patent/KR101649838B1/ko active Active
- 2007-08-24 KR KR1020147008575A patent/KR101568100B1/ko active Active
- 2007-08-24 DE DE602007012747T patent/DE602007012747D1/de active Active
- 2007-08-24 ES ES10192641T patent/ES2388591T3/es active Active
- 2007-08-24 CN CN201710126802.0A patent/CN107412179B/zh active Active
- 2007-08-24 PT PT10192627T patent/PT2311459E/pt unknown
- 2007-08-24 PT PT09156843T patent/PT2082742E/pt unknown
- 2007-08-24 CN CN200780031610.6A patent/CN101583360B/zh active Active
- 2007-08-24 DK DK11157003.2T patent/DK2384754T3/da active
- 2007-08-24 ME MEP-2013-67A patent/ME01580B/me unknown
- 2007-08-24 BR BRPI0714539A patent/BRPI0714539B8/pt active IP Right Grant
- 2007-08-24 EP EP10192627A patent/EP2311459B1/fr active Active
- 2007-08-24 RS RS20130200A patent/RS52779B/sr unknown
- 2007-08-24 TW TW096131511A patent/TWI341213B/zh active
- 2007-08-24 CL CL2007002485A patent/CL2007002485A1/es unknown
- 2007-08-24 SI SI200731010T patent/SI2311459T1/sl unknown
- 2007-08-24 US US11/844,872 patent/US8894987B2/en active Active
- 2007-08-24 PT PT10192644T patent/PT2292230E/pt unknown
- 2007-08-24 ES ES07114982T patent/ES2334466T3/es active Active
- 2007-08-24 SI SI200730563T patent/SI2080514T1/sl unknown
- 2007-08-24 PL PL09156832T patent/PL2070538T3/pl unknown
- 2007-08-24 DK DK09156838.6T patent/DK2080514T3/da active
- 2007-08-24 PT PT07114982T patent/PT1897545E/pt unknown
- 2007-08-24 DE DE602007010963T patent/DE602007010963D1/de active Active
- 2007-08-24 DK DK10192627.7T patent/DK2311459T3/da active
- 2007-08-24 EP EP09156843A patent/EP2082742B1/fr active Active
- 2007-08-24 ME MEP-2013-58A patent/ME01550B/me unknown
- 2007-08-24 KR KR1020097006064A patent/KR101205579B1/ko active Active
- 2007-08-24 KR KR1020127021463A patent/KR101455914B1/ko active Active
- 2007-08-24 MX MX2009002023A patent/MX2009002023A/es active IP Right Grant
- 2007-08-24 KR KR1020117024787A patent/KR101496510B1/ko active Active
- 2007-08-24 ES ES11157003T patent/ES2411696T3/es active Active
- 2007-08-24 KR KR1020177029318A patent/KR20170118249A/ko not_active Ceased
- 2007-08-24 JP JP2009525126A patent/JP5069300B2/ja active Active
- 2007-08-24 ES ES09156838T patent/ES2361721T3/es active Active
- 2007-08-24 SI SI200731242T patent/SI2399579T1/sl unknown
- 2007-08-24 AT AT09156832T patent/ATE489953T1/de active
- 2007-08-24 AP AP2009004770A patent/AP2009004770A0/xx unknown
- 2007-08-24 WO PCT/IB2007/002515 patent/WO2008023261A1/fr not_active Ceased
- 2007-08-24 DK DK07114982.7T patent/DK1897545T3/da active
- 2007-08-24 SI SI200731241T patent/SI2399580T1/sl unknown
- 2007-08-24 MY MYPI20090749A patent/MY146650A/en unknown
- 2007-08-24 CN CN2012101965722A patent/CN102688213A/zh active Pending
- 2007-08-24 PT PT111570131T patent/PT2399580E/pt unknown
- 2007-08-24 MY MYPI2012004970A patent/MY161079A/en unknown
- 2007-08-24 PT PT10192641T patent/PT2292229E/pt unknown
- 2007-08-24 UA UAA201107825A patent/UA104745C2/ru unknown
- 2007-08-24 EP EP11157003A patent/EP2384754B1/fr active Active
- 2007-08-24 EP EP09156832A patent/EP2070538B1/fr active Active
- 2007-08-24 PL PL09156843T patent/PL2082742T3/pl unknown
- 2007-08-24 DK DK09156832.9T patent/DK2070538T3/da active
- 2007-08-24 PT PT111570032T patent/PT2384754E/pt unknown
- 2007-08-24 ME MEP-2011-26A patent/ME01255B/fr unknown
- 2007-08-24 CN CN201510599504.4A patent/CN105213345B/zh active Active
- 2007-08-24 KR KR1020167022072A patent/KR101787605B1/ko active Active
- 2007-08-24 PL PL10192641T patent/PL2292229T3/pl unknown
- 2007-08-24 RS RS20110058A patent/RS51591B/sr unknown
- 2007-08-24 PL PL09156838T patent/PL2080514T3/pl unknown
- 2007-08-24 DK DK10192644.2T patent/DK2292230T3/da active
- 2007-08-24 AT AT07114982T patent/ATE444070T1/de active
- 2007-08-24 NZ NZ608651A patent/NZ608651A/en not_active IP Right Cessation
- 2007-08-24 DK DK11157013.1T patent/DK2399580T3/da active
- 2007-08-24 EA EA200900343A patent/EA018311B1/ru not_active IP Right Cessation
- 2007-08-24 NZ NZ574447A patent/NZ574447A/en unknown
- 2007-08-24 ES ES09156843T patent/ES2358066T3/es active Active
- 2007-08-24 IN IN1813DEN2015 patent/IN2015DN01813A/en unknown
- 2007-08-24 ME MEP-2012-105A patent/ME01482B/me unknown
- 2007-08-24 SI SI200730513T patent/SI2070538T1/sl unknown
- 2007-08-24 PL PL07114982T patent/PL1897545T3/pl unknown
- 2007-08-24 EP EP10192644A patent/EP2292230B1/fr active Active
- 2007-08-24 DK DK10192641.8T patent/DK2292229T3/da active
- 2007-08-24 EA EA201300465A patent/EA031873B1/ru not_active IP Right Cessation
- 2007-08-24 EP EP11156997A patent/EP2343071B1/fr active Active
- 2007-08-24 AU AU2007287341A patent/AU2007287341B2/en active Active
- 2007-08-24 PT PT09156832T patent/PT2070538E/pt unknown
- 2007-08-24 EP EP10192641A patent/EP2292229B1/fr active Active
- 2007-08-24 DK DK09156843.6T patent/DK2082742T3/da active
- 2007-08-24 PE PE2014000147A patent/PE20140854A1/es active IP Right Grant
- 2007-08-24 PE PE2009000362A patent/PE20091184A1/es active IP Right Grant
- 2007-08-24 RS RS20110056A patent/RS51678B/sr unknown
- 2007-08-24 DE DE602007002596T patent/DE602007002596D1/de active Active
- 2007-08-24 ES ES11157006T patent/ES2417334T3/es active Active
- 2007-08-24 DK DK11157006.5T patent/DK2399579T3/da active
- 2007-08-24 NZ NZ597760A patent/NZ597760A/xx unknown
- 2007-08-24 SI SI200731244T patent/SI2384754T1/sl unknown
- 2007-08-24 PE PE2007001153A patent/PE20080765A1/es active IP Right Grant
- 2007-08-24 PL PL11157003T patent/PL2384754T3/pl unknown
- 2007-08-24 CN CN201210135209.XA patent/CN102657630B/zh not_active Ceased
- 2007-08-24 SI SI200730989T patent/SI2292230T1/sl unknown
- 2007-08-24 AT AT09156838T patent/ATE499101T1/de active
- 2007-08-24 PT PT111570065T patent/PT2399579E/pt unknown
- 2007-08-24 PL PL11157006T patent/PL2399579T3/pl unknown
- 2007-08-24 MX MX2013014243A patent/MX360849B/es unknown
-
2009
- 2009-02-02 ZA ZA200900755A patent/ZA200900755B/xx unknown
- 2009-02-05 GT GT200900023BA patent/GT200900023BA/es unknown
- 2009-02-05 GT GT200900023A patent/GT200900023A/es unknown
- 2009-02-24 DO DO2009000026A patent/DOP2009000026A/es unknown
- 2009-02-24 IL IL197214A patent/IL197214A/en active IP Right Grant
- 2009-02-25 TN TN2009000059A patent/TN2009000059A1/fr unknown
- 2009-03-19 CO CO09028553A patent/CO6160317A2/es unknown
- 2009-03-24 MA MA31733A patent/MA30766B1/fr unknown
- 2009-03-25 CR CR10691A patent/CR10691A/es unknown
- 2009-08-14 AT AT0050909U patent/AT11571U1/de not_active IP Right Cessation
- 2009-12-11 CY CY20091101293T patent/CY1110573T1/el unknown
- 2009-12-28 HR HR20090688T patent/HRP20090688T1/hr unknown
-
2011
- 2011-02-23 CY CY20111100220T patent/CY1111897T1/el unknown
- 2011-02-23 HR HR20110130T patent/HRP20110130T1/hr unknown
- 2011-02-23 CY CY20111100217T patent/CY1111887T1/el unknown
- 2011-02-28 HR HR20110147T patent/HRP20110147T1/hr unknown
- 2011-05-17 CY CY20111100472T patent/CY1111896T1/el unknown
- 2011-05-20 HR HR20110375T patent/HRP20110375T1/hr unknown
- 2011-08-05 DO DO2011000255A patent/DOP2011000255A/es unknown
-
2012
- 2012-01-26 IL IL217787A patent/IL217787A0/en active IP Right Grant
- 2012-01-26 IL IL217790A patent/IL217790A0/en active IP Right Grant
- 2012-01-26 IL IL217794A patent/IL217794A/en active IP Right Grant
- 2012-01-26 IL IL217792A patent/IL217792A/en active IP Right Grant
- 2012-01-26 IL IL217788A patent/IL217788A0/en active IP Right Grant
- 2012-01-26 IL IL217791A patent/IL217791A/en active IP Right Grant
- 2012-01-26 IL IL217789A patent/IL217789A0/en active IP Right Grant
- 2012-03-01 JP JP2012045261A patent/JP5373133B2/ja active Active
- 2012-04-19 JP JP2012096011A patent/JP2012167102A/ja not_active Withdrawn
- 2012-07-13 JP JP2012157158A patent/JP2012229249A/ja not_active Withdrawn
- 2012-07-13 JP JP2012157159A patent/JP2012229250A/ja not_active Withdrawn
- 2012-07-13 JP JP2012157157A patent/JP5642736B2/ja active Active
- 2012-07-25 HR HRP20120613TT patent/HRP20120613T1/hr unknown
- 2012-08-07 HR HRP20120641TT patent/HRP20120641T1/hr unknown
- 2012-08-20 HR HRP20120670TT patent/HRP20120670T1/hr unknown
- 2012-08-22 CY CY20121100750T patent/CY1113231T1/el unknown
- 2012-08-22 CY CY20121100749T patent/CY1113220T1/el unknown
- 2012-09-25 CY CY20121100874T patent/CY1113141T1/el unknown
-
2013
- 2013-03-14 US US13/803,132 patent/US20140030327A1/en not_active Abandoned
- 2013-05-17 HR HRP20130433TT patent/HRP20130433T1/hr unknown
- 2013-05-17 HR HRP20130434TT patent/HRP20130434T1/hr unknown
- 2013-05-22 HR HRP20130444TT patent/HRP20130444T1/hr unknown
- 2013-05-23 US US13/901,078 patent/US8815289B2/en active Active
- 2013-05-23 US US13/901,199 patent/US20130251801A1/en not_active Abandoned
- 2013-05-23 US US13/901,218 patent/US8911719B2/en active Active
- 2013-05-23 US US13/900,873 patent/US8821929B2/en active Active
- 2013-05-23 US US13/900,963 patent/US8894988B2/en active Active
- 2013-05-23 US US13/901,122 patent/US8834925B2/en active Active
- 2013-05-23 US US13/901,027 patent/US20130251796A1/en not_active Abandoned
- 2013-05-23 US US13/901,142 patent/US20130251800A1/en not_active Abandoned
- 2013-05-23 US US13/901,047 patent/US8846086B2/en active Active
- 2013-05-23 US US13/900,933 patent/US20130259938A1/en not_active Abandoned
- 2013-05-23 US US13/901,174 patent/US20130251797A1/en not_active Abandoned
- 2013-06-13 HR HRP20130539TT patent/HRP20130539T1/hr unknown
- 2013-09-26 US US14/038,209 patent/US20140024669A1/en not_active Abandoned
- 2013-09-27 US US14/040,535 patent/US8808741B2/en active Active
-
2014
- 2014-04-22 CL CL2014001029A patent/CL2014001029A1/es unknown
- 2014-07-16 CR CR20140340A patent/CR20140340A/es unknown
- 2014-10-16 US US14/515,921 patent/US9095615B2/en active Active
- 2014-10-16 US US14/515,857 patent/US9101661B2/en active Active
- 2014-10-16 US US14/515,855 patent/US9095614B2/en active Active
- 2014-10-16 US US14/515,924 patent/US9084816B2/en active Active
- 2014-10-23 JO JOP/2014/0306A patent/JO3323B1/ar active
- 2014-10-29 JP JP2014220816A patent/JP5980881B2/ja active Active
-
2015
- 2015-06-03 US US14/729,593 patent/US9486412B2/en active Active
- 2015-06-03 US US14/729,675 patent/US9486413B2/en active Active
- 2015-06-03 US US14/729,688 patent/US9545380B2/en active Active
- 2015-06-03 US US14/729,565 patent/US9492389B2/en active Active
- 2015-06-03 US US14/729,626 patent/US9492391B2/en active Active
- 2015-06-03 US US14/729,660 patent/US9492393B2/en active Active
- 2015-06-03 US US14/729,634 patent/US9492392B2/en active Active
- 2015-06-03 US US14/729,601 patent/US9492390B2/en active Active
- 2015-09-03 IL IL241122A patent/IL241122B/en active IP Right Grant
- 2015-09-03 IL IL241121A patent/IL241121A/en active IP Right Grant
-
2016
- 2016-01-21 AR ARP160100147A patent/AR103463A2/es not_active Application Discontinuation
- 2016-07-27 JP JP2016146843A patent/JP6286491B2/ja active Active
- 2016-09-13 US US15/263,932 patent/US9775812B2/en active Active
-
2017
- 2017-01-24 US US15/413,505 patent/US9763886B2/en active Active
- 2017-01-24 US US15/413,580 patent/US9770417B2/en active Active
- 2017-01-24 US US15/413,635 patent/US9775808B2/en active Active
- 2017-01-24 US US15/413,554 patent/US9775811B2/en active Active
- 2017-01-24 US US15/413,678 patent/US9770416B2/en active Active
- 2017-01-24 US US15/413,614 patent/US9763933B2/en active Active
- 2017-01-24 US US15/413,656 patent/US9775809B2/en active Active
- 2017-01-24 US US15/413,530 patent/US9775810B2/en active Active
- 2017-03-20 CL CL2017000669A patent/CL2017000669A1/es unknown
- 2017-05-17 US US15/597,885 patent/US20170246116A1/en not_active Abandoned
- 2017-07-24 US US15/657,852 patent/US20170319496A1/en not_active Abandoned
- 2017-07-24 US US15/657,916 patent/US20170319498A1/en not_active Abandoned
- 2017-07-24 US US15/657,895 patent/US20170319497A1/en not_active Abandoned
- 2017-07-24 US US15/657,761 patent/US20170319493A1/en not_active Abandoned
- 2017-07-24 US US15/657,643 patent/US20170319491A1/en not_active Abandoned
- 2017-07-24 US US15/657,717 patent/US20170319492A1/en not_active Abandoned
- 2017-07-24 US US15/657,491 patent/US20170319489A1/en not_active Abandoned
- 2017-07-24 US US15/657,424 patent/US20170319488A1/en not_active Abandoned
- 2017-07-24 US US15/657,793 patent/US20170319494A1/en not_active Abandoned
- 2017-07-24 US US15/657,818 patent/US20170319495A1/en not_active Abandoned
- 2017-07-24 US US15/657,599 patent/US20170354607A1/en not_active Abandoned
- 2017-07-24 US US15/657,521 patent/US20170319490A1/en not_active Abandoned
- 2017-08-22 US US15/683,436 patent/US20170348240A1/en not_active Abandoned
- 2017-08-22 US US15/683,472 patent/US20170348241A1/en not_active Abandoned
- 2017-10-04 AR ARP170102763A patent/AR109797A2/es not_active Application Discontinuation
- 2017-10-04 AR ARP170102762A patent/AR109796A2/es not_active Application Discontinuation
-
2018
- 2018-01-31 US US15/885,413 patent/US10076499B2/en active Active
- 2018-01-31 US US15/885,254 patent/US10076498B2/en active Active
- 2018-01-31 US US15/885,074 patent/US20180369150A1/en not_active Abandoned
- 2018-08-28 US US16/115,024 patent/US20190000767A1/en not_active Abandoned
-
2020
- 2020-07-17 US US16/931,803 patent/US20210169810A1/en not_active Abandoned
- 2020-09-21 US US17/027,307 patent/US11304909B2/en active Active
- 2020-09-21 US US17/027,222 patent/US11304908B2/en active Active
- 2020-09-21 US US17/027,088 patent/US11298322B2/en active Active
-
2022
- 2022-08-22 US US17/892,553 patent/US11904055B2/en active Active
-
2023
- 2023-05-05 US US18/143,927 patent/US11826472B2/en active Active
- 2023-06-05 US US18/205,786 patent/US11938225B2/en active Active
- 2023-09-27 US US18/475,755 patent/US11964056B1/en active Active
-
2024
- 2024-03-13 US US18/603,884 patent/US12246094B2/en active Active
- 2024-08-21 US US18/811,146 patent/US20240408024A1/en active Pending
- 2024-11-20 US US18/953,665 patent/US20250073173A1/en not_active Abandoned
- 2024-11-20 US US18/953,603 patent/US12280152B2/en active Active
-
2025
- 2025-04-09 US US19/174,583 patent/US12396955B2/en active Active
- 2025-07-24 US US19/279,603 patent/US20250352480A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TN2009000059A1 (fr) | Formes de dosage pharmaceutiques orales anti-manipulation contenant un analgesique opioide | |
| MA51204B1 (fr) | Formes pharmaceutiques comprenant un inhibiteur de la kallicréine plasmatique | |
| HRP20120004T1 (en) | Dipeptidyl peptidase inhibitors for treating diabetes | |
| TW200833370A (en) | Pharmaceutical composition containing low substituted hydroxypropylcellulose | |
| MA29734B1 (fr) | Formes posologiques solides de valsartan et d'amlodipine et procede de preparation afferent | |
| MA30807B1 (fr) | Compositions pharmaceutiques. | |
| MA35513B1 (fr) | Compositions pharmaceutiques comprenant 40 - o - ( 2 - hydroxy) éthyl - rapamycine | |
| JO2515B1 (en) | Gamma-Crystalline form of ivabradine hydrochloride,a process for its preparation and pharmaceutical composition containing it | |
| MA34474B1 (fr) | Agonistes de gpr40 | |
| PL415001A1 (pl) | Kompozycje farmaceutyczne zawierające kwas mykofenolowy lub sól mykofenolanową | |
| IL193252A0 (en) | N-hydroxyacrylamide compounds | |
| BRPI0509184A (pt) | composições farmacêuticas | |
| MA33679B1 (fr) | Derives de 2-oxo-1-pyrrolidinyle imidazothiadiazole | |
| BRPI0410044A (pt) | forma de dosagem contendo pantoprazol como ingrediente ativo | |
| EA201200485A1 (ru) | Перорально распадающаяся фармацевтическая лекарственная форма, содержащая арипипразол | |
| BRPI0519198A2 (pt) | moduladores de delta-opiàide tricÍclicos | |
| EA200800698A1 (ru) | Способ стабилизации фармацевтических форм для введения, включающих микроорганизмы | |
| EA201001108A1 (ru) | Диспергируемые во рту таблетки, содержащие основание эсциталопрама, и способ их получения | |
| IL191670A0 (en) | Compounds for the inhibition of apoptosis | |
| BRPI0509014A (pt) | comprimidos desintegráveis que compreendem licarbazepina | |
| EA200900622A1 (ru) | Фармацевтическая композиция, содержащая полиморфную форму 1 клопидогрела гидросульфата | |
| EA201000118A1 (ru) | Сублингвальные или трансбуккальные композиции, содержащие янтарную кислоту и предназначенные для лечения болезни альцгеймера | |
| FR2898059B1 (fr) | Composition phytohormonale contenant de la sauge | |
| NO20044900L (no) | Progestagene doseringsenheter | |
| RU2008132511A (ru) | Способ лечения гипертензивных внутримозговых кровоизлияний |