MA30814B1 - Nouvelles compositions en depot injectables et leur procede de fabrication - Google Patents

Nouvelles compositions en depot injectables et leur procede de fabrication

Info

Publication number
MA30814B1
MA30814B1 MA31821A MA31821A MA30814B1 MA 30814 B1 MA30814 B1 MA 30814B1 MA 31821 A MA31821 A MA 31821A MA 31821 A MA31821 A MA 31821A MA 30814 B1 MA30814 B1 MA 30814B1
Authority
MA
Morocco
Prior art keywords
manufacture
novel injectable
deposition compositions
deposition
compositions
Prior art date
Application number
MA31821A
Other languages
English (en)
Inventor
Rajesh Jain
Kour Chand Jindal
Sampath Kumar Devarajan
Original Assignee
Panacea Biotec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panacea Biotec Ltd filed Critical Panacea Biotec Ltd
Publication of MA30814B1 publication Critical patent/MA30814B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

NOUVELLES COMPOSITIONS EN DÉPÔT INJECTABLES COMPRENANT AU MOINS UN PRINCIPE ACTIF AVEC ÉVENTUELLEMENT UN OU DES EXCIPIENTS DE QUALITÉ PHARMACEUTIQUE, SE PRÉSENTANT SOUS LA FORME D'UN SYSTÈME MULTI-COMPOSANT QUI, LORS DE L'ADMINISTRATION À UN SUJET QUI EN A BESOIN, FORME IN SITU UN DÉPÔT OU UN IMPLANT EN GEL AU POINT D'INJECTION AU MOMENT DU CONTACT AVEC DES LIQUIDES ORGANIQUES. SONT ÉGALEMENT DÉCRITS UN PROCÉDÉ DE FABRICATION DE TELLES COMPOSITION ET LEUR MÉTHODE D'UTILISATION.
MA31821A 2006-10-05 2009-04-27 Nouvelles compositions en depot injectables et leur procede de fabrication MA30814B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN2195DE2006 2006-10-05

Publications (1)

Publication Number Publication Date
MA30814B1 true MA30814B1 (fr) 2009-10-01

Family

ID=39268891

Family Applications (2)

Application Number Title Priority Date Filing Date
MA31821A MA30814B1 (fr) 2006-10-05 2009-04-27 Nouvelles compositions en depot injectables et leur procede de fabrication
MA31824A MA30817B1 (fr) 2006-10-05 2009-04-27 Nouvelles compositions en depot injectables et leur procede de fabrication.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MA31824A MA30817B1 (fr) 2006-10-05 2009-04-27 Nouvelles compositions en depot injectables et leur procede de fabrication.

Country Status (17)

Country Link
US (2) US20100098735A1 (fr)
EP (2) EP2089000A2 (fr)
JP (2) JP2010505819A (fr)
KR (2) KR20090087441A (fr)
CN (2) CN101541313A (fr)
AR (1) AR063120A1 (fr)
AU (2) AU2007303793A1 (fr)
BR (2) BRPI0718288A2 (fr)
CA (2) CA2665101A1 (fr)
CL (1) CL2007002851A1 (fr)
EA (1) EA200970348A1 (fr)
IL (2) IL197947A0 (fr)
MA (2) MA30814B1 (fr)
MX (2) MX2009003735A (fr)
RU (1) RU2009116933A (fr)
TN (2) TN2009000124A1 (fr)
WO (2) WO2008041245A2 (fr)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
EP1589901A4 (fr) * 2002-12-20 2006-08-09 Generipharm Inc Injection intracutanee
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
US9205046B2 (en) * 2005-04-25 2015-12-08 The Governing Council Of The University Of Toronto Enhanced stability of inverse thermal gelling composite hydrogels
US8852638B2 (en) 2005-09-30 2014-10-07 Durect Corporation Sustained release small molecule drug formulation
PL2359808T3 (pl) 2006-08-09 2013-10-31 Intarcia Therapeutics Inc Osmotyczne systemy dostawcze i zespoły tłokowe
EP2157967B1 (fr) 2007-04-23 2013-01-16 Intarcia Therapeutics, Inc Formulations en suspension de peptides insulinotropes et leurs utilisations
EP2152315B1 (fr) 2007-05-25 2016-01-06 Indivior UK Limited Formulations d'administration prolongée de composés de rispéridone
CN101677987A (zh) * 2007-06-22 2010-03-24 赛多斯有限责任公司 不含吐温80的多西他赛的增溶制剂
KR101892745B1 (ko) 2007-06-25 2018-08-28 오쓰까 세이야꾸 가부시키가이샤 코어/셀 구조를 가진 미소구
WO2009060473A2 (fr) * 2007-11-06 2009-05-14 Panacea Biotec Limited Compositions injectables, procédés et utilisations correspondantes
EP2240155B1 (fr) 2008-02-13 2012-06-06 Intarcia Therapeutics, Inc Dispositifs, formulations et méthodes d administration de plusieurs agents bénéfiques
JP2011514349A (ja) 2008-03-07 2011-05-06 サイドース・エルエルシー フルベストラント配合物
US8524267B2 (en) * 2008-04-18 2013-09-03 Warsaw Orthopedic, Inc. Dexamethasone formulations in a biodegradable material
CN101569622B (zh) * 2008-04-30 2012-11-21 天津药物研究院 一种用于注射给药的药物制剂及其制备方法
EA014044B1 (ru) * 2008-07-09 2010-08-30 Общество С Ограниченной Ответственностью "Аква-Альянс" Наносомальная лекарственная форма препарата пролонгированного действия для лечения гепатита с (варианты)
EP3685837A1 (fr) * 2008-09-04 2020-07-29 Amylin Pharmaceuticals, LLC Formulations à libération prolongée à base de supports non aqueux
US9498431B2 (en) 2008-12-10 2016-11-22 Jianjian Xu Controlled releasing composition
US9636255B2 (en) 2009-02-13 2017-05-02 Dose Medical Corporation Uveoscleral drug delivery implant and methods for implanting the same
CA2754200A1 (fr) * 2009-03-02 2010-09-10 Assistance Publique - Hopitaux De Paris Biomateriau injectable
US12478503B2 (en) 2009-05-18 2025-11-25 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
JP5937004B2 (ja) 2009-05-18 2016-06-22 ドーズ メディカル コーポレーションＤｏｓｅ Ｍｅｄｉｃａｌ Ｃｏｒｐｏｒａｔｉｏｎ 薬剤溶出眼内インプラント
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
EP3323423B1 (fr) 2009-09-28 2020-06-17 Intarcia Therapeutics, Inc Établissement rapide et/ou arrêt rapide d'une administration constante substantielle de médicament
CN101669942A (zh) * 2009-09-29 2010-03-17 北京华禧联合科技发展有限公司 难溶性药物组合物
US8541465B2 (en) * 2009-10-19 2013-09-24 Scidose, Llc Docetaxel formulations with lipoic acid and/or dihydrolipoic acid
US8912228B2 (en) 2009-10-19 2014-12-16 Scidose Llc Docetaxel formulations with lipoic acid
US20110092579A1 (en) * 2009-10-19 2011-04-21 Scidose Llc Solubilized formulation of docetaxel
US7772274B1 (en) 2009-10-19 2010-08-10 Scidose, Llc Docetaxel formulations with lipoic acid
US8476310B2 (en) 2009-10-19 2013-07-02 Scidose Llc Docetaxel formulations with lipoic acid
US9504698B2 (en) * 2009-10-29 2016-11-29 Warsaw Orthopedic, Inc. Flowable composition that sets to a substantially non-flowable state
JP5486690B2 (ja) 2009-11-16 2014-05-07 イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ メラノコルチン受容体リガンドの医薬組成物
BR112012023303A2 (pt) * 2010-03-15 2020-08-25 Ipsen Pharma S.A.S. composição farmacêutica de ligantes do receptor do secretagogo do hormônio de crescimento.
JP2013523752A (ja) * 2010-03-29 2013-06-17 エボニック デグサ コーポレイション 局所投与部位における医薬組成物の保持改善のための組成物および方法
US10350159B2 (en) * 2010-05-31 2019-07-16 Laboratories Farmacéuticos Rovi, S.A. Paliperidone implant formulation
ES2390439B1 (es) 2012-08-03 2013-09-27 Laboratorios Farmacéuticos Rovi, S.A. Composición inyectable
US10285936B2 (en) 2010-05-31 2019-05-14 Laboratorios Farmacéuticos Rovi, S.A. Injectable composition with aromatase inhibitor
US10335366B2 (en) * 2010-05-31 2019-07-02 Laboratorios Farmacéuticos Rovi, S.A. Risperidone or paliperidone implant formulation
GB2513060B (en) 2010-06-08 2015-01-07 Rb Pharmaceuticals Ltd Microparticle buprenorphine suspension
US9272044B2 (en) 2010-06-08 2016-03-01 Indivior Uk Limited Injectable flowable composition buprenorphine
DE102010023949A1 (de) * 2010-06-16 2011-12-22 F. Holzer Gmbh In-situ Lecithin-Mikroemulsionsgel-Formulierung
US20120046225A1 (en) 2010-07-19 2012-02-23 The Regents Of The University Of Colorado, A Body Corporate Stable glucagon formulations for the treatment of hypoglycemia
JP5575269B2 (ja) * 2010-08-24 2014-08-20 大塚製薬株式会社 カルボスチリル誘導体並びにシリコーンオイル及び／又はシリコーンオイル誘導体を含有する懸濁液及びケーキ組成物
CN103491961B (zh) * 2010-10-28 2018-01-02 艾库斯制药有限公司 阿立哌唑组合物和用于其经皮给药的方法
US9757374B2 (en) 2010-10-28 2017-09-12 Aequus Pharmaceuticals Inc. Aripiprazole compositions and methods for its transdermal delivery
US9668915B2 (en) 2010-11-24 2017-06-06 Dose Medical Corporation Drug eluting ocular implant
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
WO2012122535A2 (fr) 2011-03-10 2012-09-13 Xeris Pharmaceuticals, Inc. Formulations stables pour injection parentérale de médicaments peptidiques
ES2972387T3 (es) * 2011-03-18 2024-06-12 Alkermes Pharma Ireland Ltd Composiciones farmacéuticas que comprenden ésteres de sorbitán
US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
JP6117811B2 (ja) 2011-10-31 2017-04-19 ゼリス ファーマシューティカルズ インコーポレイテッド 糖尿病を処置するための製剤
US11179468B2 (en) 2012-04-09 2021-11-23 Eagle Pharmaceuticals, Inc. Fulvestrant formulations
JOP20200109A1 (ar) * 2012-04-23 2017-06-16 Otsuka Pharma Co Ltd مستحضر قابل للحقن
EP2705835A1 (fr) * 2012-06-08 2014-03-12 Ipsen Pharma S.A.S. Aqueous gelling compositions of soluble active pharmaceutical peptides providing modified release
CN103483353B (zh) * 2012-06-13 2016-02-24 上海现代药物制剂工程研究中心有限公司 二硫杂环戊烯并吡咯酮化合物的纳米粒及制备方法
US9125805B2 (en) 2012-06-27 2015-09-08 Xeris Pharmaceuticals, Inc. Stable formulations for parenteral injection of small molecule drugs
US9018162B2 (en) 2013-02-06 2015-04-28 Xeris Pharmaceuticals, Inc. Methods for rapidly treating severe hypoglycemia
US10517759B2 (en) 2013-03-15 2019-12-31 Glaukos Corporation Glaucoma stent and methods thereof for glaucoma treatment
KR101811797B1 (ko) * 2013-04-03 2017-12-22 동국제약 주식회사 도네페질을 포함하는 비경구투여용 약제학적 조성물
WO2014179615A2 (fr) * 2013-05-01 2014-11-06 Dae Won Park Copolymères biodégradables, systèmes comprenant les copolymères et leurs procédés de formation et d'utilisation
EP3063218A4 (fr) * 2013-08-22 2017-07-26 Polyvalor, Limited Partnership Gels poreux et leurs procédés de préparation
JP2015093854A (ja) * 2013-11-12 2015-05-18 株式会社クレハ 水性組成物および加水分解抑制方法
CH708890B1 (de) * 2013-11-22 2018-03-15 Sandel Thomas Ball, vorzugsweise Golfball, sowie ein mit dem Ball kommunizierbares elektronisches Gerät.
US20150174254A1 (en) 2013-12-23 2015-06-25 Mcneil-Ppc, Inc. Topical gel compositions including polycaprolactone polymer and methods for enhancing the topical application of a benefit agent
GB201404139D0 (en) 2014-03-10 2014-04-23 Rb Pharmaceuticals Ltd Sustained release buprenorphine solution formulations
AU2015266850B2 (en) 2014-05-29 2019-12-05 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
KR102428675B1 (ko) 2014-08-06 2022-08-02 엑스에리스 파머수티클스, 인크. 페이스트의 피내 및／또는 피하 주사를 위한 주사기, 키트, 및 방법
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
MA40844A (fr) * 2014-11-10 2017-09-20 Glaxosmithkline Ip No 2 Ltd Compositions pharmaceutiques à action prolongée pour l'hépatite c
EP3028721A1 (fr) * 2014-12-05 2016-06-08 Exchange Imaging Technologies GmbH Formulation de nano-structures avec caractéristique inverse de gélification pour injection
KR101692314B1 (ko) * 2015-03-27 2017-01-03 주식회사 주빅 지용성 약물의 생분해성 고분자 내 용해 시스템: 스마트 폴리머 시스템
US9844558B1 (en) 2015-04-30 2017-12-19 Amag Pharmaceuticals, Inc. Methods of reducing risk of preterm birth
ES2968262T3 (es) 2015-06-03 2024-05-08 I2O Therapeutics Inc Sistemas de colocación de implantes
US9649364B2 (en) 2015-09-25 2017-05-16 Xeris Pharmaceuticals, Inc. Methods for producing stable therapeutic formulations in aprotic polar solvents
WO2017040853A1 (fr) 2015-09-02 2017-03-09 Glaukos Corporation Implants d'administration de médicament présentant capacité d'administration bidirectionnelle
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
US11590205B2 (en) 2015-09-25 2023-02-28 Xeris Pharmaceuticals, Inc. Methods for producing stable therapeutic glucagon formulations in aprotic polar solvents
US20170128424A1 (en) * 2015-11-11 2017-05-11 Qrono, Inc. Sustained release pharmaceutical compositions and methods of use
WO2017105512A1 (fr) * 2015-12-18 2017-06-22 Proinvet Innovations S.A. Formulations et procédés de commande du cycle de reproduction et de l'ovulation
CA3022830A1 (fr) 2016-04-20 2017-10-26 Harold Alexander Heitzmann Dispositif d'administration de medicament oculaire bioresorbable
CA3022693A1 (fr) * 2016-05-16 2017-11-23 Amag Pharmaceuticals, Inc. Compositions polymeres a liberation prolongee a base de caproate d'hydroxyprogesterone et leurs procedes d'utilisation
KR20240037175A (ko) 2016-05-16 2024-03-21 인타르시아 세라퓨틱스 인코포레이티드 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
WO2018015915A1 (fr) * 2016-07-22 2018-01-25 Cadila Healthcare Limited Composition à libération parentérale contrôlée d'un antipsychotique atypique.
AU2018206539A1 (en) 2017-01-03 2019-07-18 Intarcia Therapeutics, Inc. Methods comprising continuous administration of a GLP-1 receptor agonist and co-administration of a drug
US20190380967A1 (en) * 2017-01-23 2019-12-19 Savior Lifetec Corporation Preparation of microparticles of an active ingredient
CN106822039A (zh) * 2017-01-24 2017-06-13 广州帝奇医药技术有限公司 水难溶或微溶性药物缓释组合物及其制备方法
CN106822043A (zh) * 2017-01-24 2017-06-13 广州帝奇医药技术有限公司 利培酮缓释组合物及其制备方法
CN106822042A (zh) * 2017-01-24 2017-06-13 广州帝奇医药技术有限公司 一种利培酮缓释组合物及其制备方法
CN106727422B (zh) * 2017-03-09 2018-10-02 王秋玉 一种聚对二氧环己酮为核的核-壳双层微球及其制备方法和应用
CN117085022A (zh) 2017-06-02 2023-11-21 Xeris药物公司 抗沉淀的小分子药物制剂
EP3681491A4 (fr) 2017-09-11 2021-06-30 Atossa Therapeutics, Inc. Procédés pour la fabrication et l'utilisation d'endoxifène
GB2568579B (en) * 2017-09-15 2022-06-29 Oxular Ltd Ophthalmic drug compositions
PT3562485T (pt) * 2018-03-23 2020-08-27 Laboratoires Major Composições e métodos não hormonais para contraceção masculina compreendendo (r)-silodosina
PE20210047A1 (es) 2018-06-12 2021-01-08 Farm Rovi Lab Sa Composicion inyectable
BR112021007900A2 (pt) * 2018-08-10 2021-08-03 Ephemeral Solutions, Inc. partículas contendo agentes de coloração e métodos de uso das mesmas
US11896715B2 (en) 2019-06-21 2024-02-13 Korea University Research And Business Foundation In vivo bulking agent, injection comprising same, and preparation method therefor
WO2021003433A1 (fr) 2019-07-03 2021-01-07 Atossa Therapeutics, Inc. Compositions d'endoxifène à libération prolongée
CN111388744B (zh) * 2020-01-15 2021-05-18 华中科技大学 一种凝胶贮库及其制法与制备术后止血制剂的应用
CN116669717A (zh) * 2020-08-17 2023-08-29 美国人福制药公司 长效原位成型/胶凝组合物
CN111956599B (zh) * 2020-09-29 2023-02-17 江苏集萃新型药物制剂技术研究所有限公司 皮下植入药剂及其组合物和制备方法
KR102266384B1 (ko) * 2021-01-25 2021-06-21 주식회사 울트라브이 필러용 생분해성 고분자 미세입자, 이를 포함한 필러용 동결건조체, 그 제조방법 및 상기 동결건조체를 포함하는 필러용 주사제
US12318387B2 (en) 2021-07-16 2025-06-03 Laboratorios Farmaceuticos Rovi, S.A. Method of treating acute exacerbation of schizophrenia with long-acting injectable depot composition
US12594236B2 (en) 2021-07-16 2026-04-07 Laboratorios Farmaceuticos Rovi, S.A. Method of treating acute exacerbation of schizophrenia with long-acting injectable depot composition
KR102652905B1 (ko) * 2021-08-09 2024-04-01 주식회사 메디폴리머 주사용 사전-제형 및 이를 이용한 도네페질 초기방출 억제형 키트
TW202313047A (zh) 2021-09-21 2023-04-01 西班牙商禾霏藥品實驗室有限公司 抗精神病可注射儲積型組合物
WO2023233051A1 (fr) 2022-05-18 2023-12-07 Laboratorios Farmacéuticos Rovi, S.A. Compositions injectables à libération prolongée destinées à être utilisées dans le cadre du traitement par rispéridone en association avec des inhibiteurs de l'enzyme cyp2d6
WO2024151625A1 (fr) * 2023-01-10 2024-07-18 Georgetown University Compositions de plga non toxiques et leurs procédés de fabrication et d'utilisation
CN116850146B (zh) * 2023-05-22 2024-05-14 济南大学 伏硫西汀自由碱或其药用盐长效缓释制剂及其制备方法
WO2025153747A1 (fr) 2024-01-17 2025-07-24 Laboratorios Farmacéuticos Rovi, S.A. Compositions et schémas posologiques d'inhibiteurs d'aromatase améliorés
USD1137672S1 (en) 2024-08-27 2026-07-28 Glaukos Corporation Drug eluting ocular implant

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242910A (en) * 1992-10-13 1993-09-07 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
EP0669128B1 (fr) * 1992-11-17 2000-01-05 Yoshitomi Pharmaceutical Industries, Ltd. Microsphere a liberation prolongee contenant un antipshychotique et procede de production
US5650173A (en) * 1993-11-19 1997-07-22 Alkermes Controlled Therapeutics Inc. Ii Preparation of biodegradable microparticles containing a biologically active agent
GB9718986D0 (en) * 1997-09-09 1997-11-12 Danbiosyst Uk Controlled release microsphere delivery system
WO2002058672A2 (fr) * 2001-01-26 2002-08-01 Debio Recherche Pharmaceutique S.A. Microparticules de polymere biodegradable encapsulant une substance biologiquement active et formulations pharmaceutiques a liberation prolongee contenant lesdites particules
ES2541908T3 (es) * 2001-10-10 2015-07-28 Pierre Fabre Medicament Microesferas biodegradables de liberación prolongada y su procedimiento de preparación
TW200719903A (en) * 2005-04-19 2007-06-01 Combinatorx Inc Compositions for the treatment of neoplasms

Also Published As

Publication number Publication date
WO2008041245A2 (fr) 2008-04-10
IL197947A0 (en) 2009-12-24
CA2665105A1 (fr) 2008-04-10
AU2007303793A1 (en) 2008-04-10
RU2009116933A (ru) 2010-11-10
KR20090087441A (ko) 2009-08-17
EA200970348A1 (ru) 2009-10-30
MX2009003737A (es) 2009-06-16
WO2008041246A2 (fr) 2008-04-10
KR20090094811A (ko) 2009-09-08
WO2008041245A3 (fr) 2008-05-22
BRPI0718288A2 (pt) 2013-11-19
CN101541313A (zh) 2009-09-23
JP2010505821A (ja) 2010-02-25
WO2008041246A3 (fr) 2008-05-29
IL197946A0 (en) 2009-12-24
JP2010505819A (ja) 2010-02-25
BRPI0720346A2 (pt) 2014-06-24
CN101541316A (zh) 2009-09-23
US20100015195A1 (en) 2010-01-21
CA2665101A1 (fr) 2008-04-10
TN2009000125A1 (en) 2010-10-18
MA30817B1 (fr) 2009-10-01
TN2009000124A1 (en) 2010-10-18
US20100098735A1 (en) 2010-04-22
MX2009003735A (es) 2009-04-22
EP2086505A2 (fr) 2009-08-12
AU2007303794A1 (en) 2008-04-10
CL2007002851A1 (es) 2008-01-18
EP2089000A2 (fr) 2009-08-19
AR063120A1 (es) 2008-12-30

Similar Documents

Publication Publication Date Title
EP4628165A3 (fr) Composé de camptothécine, son procédé de préparation et son application
ATE424848T1 (de) Pharmazeutische zusammensetzungen für die kontrollierte freigabe von biologischen wirkstoffen
BRPI0512660A (pt) tablete carregável, e, método para a preparação de um tablete
MA30817B1 (fr) Nouvelles compositions en depot injectables et leur procede de fabrication.
EA200800161A1 (ru) Новые фармацевтические композиции с модифицированным высвобождением и способ получения таких композиций
EP4009400A4 (fr) Matériau actif d'anode composite, son procédé de préparation et anode le comprenant
CL2007000789A1 (es) Compuestos derivados de malonamida, inhibidores de la gamma-secretasa; proceso de preparacion; composicion farmaceutica; y su uso en el tratamiento de la enfermedad de alzheimer.
UY27990A1 (es) Derivados de pirrolidona como inhibidores de maob
MA28342A1 (fr) Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
Liu et al. Tendon‐derived stem cell differentiation in the degenerative tendon microenvironment
WO2008039351A3 (fr) Procédé de fabrication de comprimés contenant des agents de qualité pharmacologique
EP2170878A4 (fr) Nouveaux dérivés de benzamidine, procédé de préparation correspondant et composition pharmaceutique les contenant qui permet de prévenir ou de traiter l'ostéoporose
DK1969003T3 (da) Anvendelser af et neurotrofisk faktor-protein
Conforti et al. Musculoskeletal adverse drug reactions: a review of literature and data from ADR spontaneous reporting databases
EP1905823A4 (fr) Levure composite adaptée à la fermentation d'alcool en concentration élevée
Basu et al. Recent developments in islet biology: a review with patient perspectives
ATE505464T1 (de) Feste form von amg 706 und pharmazeutische zusammensetzungen davon
DE602004017512D1 (de) Neues peptid, verfahren zu dessen herstellung und pharmazeutische zusammensetzung, die das peptid enthält
FR3140516B1 (fr) Support pour toitures végétalisées
DE602004017214D1 (de) Antibakterielle und/oder gegen protozoen wirksame nitroimidazolderivatverbindungen mit ureasehemmender wirkung, verfahren zur herstellung dieser verbindungen und deren verwendung in pharmazeutischen zusammensetzungen und medikamenten
EP3763735A4 (fr) Procédé de préparation d'un biomatériau ayant une tyrosine fonctionnalisée de manière sélective, biomatériau ayant une tyrosine fonctionnalisée de manière sélective, et composition pharmaceutique le contenant en tant que principe actif
DK1976538T3 (da) Farmaceutisk formulering til behandling af slidgigt indeholdende clodronsyre og hyaluronsyre
EP4122476A4 (fr) Composition pharmaceutique pour la prévention ou le traitement de la maladie de charcot-marie, comprenant des cellules souches mésenchymateuses ou de l'insuline sécrétée par des cellules souches mésenchymateuses
WO2020227558A3 (fr) Maximisation de la distribution et réduction au minimum du lavage de produits à injecter dans un os et procédé d'extraction améliorée d'aspirat
FR2885807A1 (fr) Composition pharmaceutique solide a liberation prolongee de 1-(2,3,4-trimethoxybenzyl) piperazine, et procede de preparation