MA30817B1 - Nouvelles compositions en depot injectables et leur procede de fabrication. - Google Patents
Nouvelles compositions en depot injectables et leur procede de fabrication.Info
- Publication number
- MA30817B1 MA30817B1 MA31824A MA31824A MA30817B1 MA 30817 B1 MA30817 B1 MA 30817B1 MA 31824 A MA31824 A MA 31824A MA 31824 A MA31824 A MA 31824A MA 30817 B1 MA30817 B1 MA 30817B1
- Authority
- MA
- Morocco
- Prior art keywords
- compositions
- tarnsulosine
- letrozole
- manufacture
- novel injectable
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 230000008021 deposition Effects 0.000 title 1
- 239000007972 injectable composition Substances 0.000 abstract 2
- HPJKCIUCZWXJDR-UHFFFAOYSA-N letrozole Chemical compound C1=CC(C#N)=CC=C1C(N1N=CN=C1)C1=CC=C(C#N)C=C1 HPJKCIUCZWXJDR-UHFFFAOYSA-N 0.000 abstract 2
- 229960003881 letrozole Drugs 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical compound C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000011859 microparticle Substances 0.000 abstract 1
- 239000002105 nanoparticle Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
NOUVELLES COMPOSITIONS INJECTABLES COMPRENANT COMME PRINCIPE ACTIF DE LA TARNSULOSINE OU DU LÉTROZOLE OU BIEN DES SELS, DÉRIVÉS, ISOMÈRES, POLYMORPHES, SOLVATES, HYDRATES, ANALOGUES, ÉNANTIOMÈRES, FORMES TAUTOMÈRES OU MÉLANGES DE QUALITÉ PHARMACEUTIQUE DE CES SUBSTANCES AINSI QU'UN OU PLUSIEURS EXCIPIENTS DE QUALITÉ PHARMACEUTIQUE. CES COMPOSITIONS, QUI SE PRÉSENTENT DE PRÉFÉRENCE SOUS FORME DE MICROPARTICULES OU DE NANOPARTICULES BIODÉGRADABLES, PEUVENT ÊTRE ÉVENTUELLEMENT RECONSTITUÉES AVEC UN VÉHICULE HYDROALCOOLIQUE AQUEUX OU LIQUIDE HUILEUX AVANT ADMINISTRATION. LES COMPOSITIONS INJECTABLES DE L'INVENTION FORMENT DE PRÉFÉRENCE UN DÉPÔT LORS DE LEUR ADMINISTRATION IN VIVO ET SE PRÉSENTENT IN SITU SOUS LA FORME D'UNE COMPOSITION OU D'UN IMPLANT GÉLIFIANT ASSURANT LA LIBÉRATION DE TARNSULOSINE OU LÉTROZOLE PENDANT UN LAPS DE TEMPS PROLONGÉ. SONT ÉGALEMENT DÉCRIT UN PROCÉDÉ DE FABRICATION ET UNE MÉTHODE D'UTILISATION DE CES NOUVELLES COMPOSITIONS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2195DE2006 | 2006-10-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA30817B1 true MA30817B1 (fr) | 2009-10-01 |
Family
ID=39268891
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA31821A MA30814B1 (fr) | 2006-10-05 | 2009-04-27 | Nouvelles compositions en depot injectables et leur procede de fabrication |
| MA31824A MA30817B1 (fr) | 2006-10-05 | 2009-04-27 | Nouvelles compositions en depot injectables et leur procede de fabrication. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA31821A MA30814B1 (fr) | 2006-10-05 | 2009-04-27 | Nouvelles compositions en depot injectables et leur procede de fabrication |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20100098735A1 (fr) |
| EP (2) | EP2089000A2 (fr) |
| JP (2) | JP2010505819A (fr) |
| KR (2) | KR20090087441A (fr) |
| CN (2) | CN101541313A (fr) |
| AR (1) | AR063120A1 (fr) |
| AU (2) | AU2007303793A1 (fr) |
| BR (2) | BRPI0718288A2 (fr) |
| CA (2) | CA2665101A1 (fr) |
| CL (1) | CL2007002851A1 (fr) |
| EA (1) | EA200970348A1 (fr) |
| IL (2) | IL197947A0 (fr) |
| MA (2) | MA30814B1 (fr) |
| MX (2) | MX2009003735A (fr) |
| RU (1) | RU2009116933A (fr) |
| TN (2) | TN2009000124A1 (fr) |
| WO (2) | WO2008041245A2 (fr) |
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| EP2152315B1 (fr) | 2007-05-25 | 2016-01-06 | Indivior UK Limited | Formulations d'administration prolongée de composés de rispéridone |
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| CN106822042A (zh) * | 2017-01-24 | 2017-06-13 | 广州帝奇医药技术有限公司 | 一种利培酮缓释组合物及其制备方法 |
| CN106727422B (zh) * | 2017-03-09 | 2018-10-02 | 王秋玉 | 一种聚对二氧环己酮为核的核-壳双层微球及其制备方法和应用 |
| CN117085022A (zh) | 2017-06-02 | 2023-11-21 | Xeris药物公司 | 抗沉淀的小分子药物制剂 |
| EP3681491A4 (fr) | 2017-09-11 | 2021-06-30 | Atossa Therapeutics, Inc. | Procédés pour la fabrication et l'utilisation d'endoxifène |
| GB2568579B (en) * | 2017-09-15 | 2022-06-29 | Oxular Ltd | Ophthalmic drug compositions |
| PT3562485T (pt) * | 2018-03-23 | 2020-08-27 | Laboratoires Major | Composições e métodos não hormonais para contraceção masculina compreendendo (r)-silodosina |
| PE20210047A1 (es) | 2018-06-12 | 2021-01-08 | Farm Rovi Lab Sa | Composicion inyectable |
| BR112021007900A2 (pt) * | 2018-08-10 | 2021-08-03 | Ephemeral Solutions, Inc. | partículas contendo agentes de coloração e métodos de uso das mesmas |
| US11896715B2 (en) | 2019-06-21 | 2024-02-13 | Korea University Research And Business Foundation | In vivo bulking agent, injection comprising same, and preparation method therefor |
| WO2021003433A1 (fr) | 2019-07-03 | 2021-01-07 | Atossa Therapeutics, Inc. | Compositions d'endoxifène à libération prolongée |
| CN111388744B (zh) * | 2020-01-15 | 2021-05-18 | 华中科技大学 | 一种凝胶贮库及其制法与制备术后止血制剂的应用 |
| CN116669717A (zh) * | 2020-08-17 | 2023-08-29 | 美国人福制药公司 | 长效原位成型/胶凝组合物 |
| CN111956599B (zh) * | 2020-09-29 | 2023-02-17 | 江苏集萃新型药物制剂技术研究所有限公司 | 皮下植入药剂及其组合物和制备方法 |
| KR102266384B1 (ko) * | 2021-01-25 | 2021-06-21 | 주식회사 울트라브이 | 필러용 생분해성 고분자 미세입자, 이를 포함한 필러용 동결건조체, 그 제조방법 및 상기 동결건조체를 포함하는 필러용 주사제 |
| US12318387B2 (en) | 2021-07-16 | 2025-06-03 | Laboratorios Farmaceuticos Rovi, S.A. | Method of treating acute exacerbation of schizophrenia with long-acting injectable depot composition |
| US12594236B2 (en) | 2021-07-16 | 2026-04-07 | Laboratorios Farmaceuticos Rovi, S.A. | Method of treating acute exacerbation of schizophrenia with long-acting injectable depot composition |
| KR102652905B1 (ko) * | 2021-08-09 | 2024-04-01 | 주식회사 메디폴리머 | 주사용 사전-제형 및 이를 이용한 도네페질 초기방출 억제형 키트 |
| TW202313047A (zh) | 2021-09-21 | 2023-04-01 | 西班牙商禾霏藥品實驗室有限公司 | 抗精神病可注射儲積型組合物 |
| WO2023233051A1 (fr) | 2022-05-18 | 2023-12-07 | Laboratorios Farmacéuticos Rovi, S.A. | Compositions injectables à libération prolongée destinées à être utilisées dans le cadre du traitement par rispéridone en association avec des inhibiteurs de l'enzyme cyp2d6 |
| WO2024151625A1 (fr) * | 2023-01-10 | 2024-07-18 | Georgetown University | Compositions de plga non toxiques et leurs procédés de fabrication et d'utilisation |
| CN116850146B (zh) * | 2023-05-22 | 2024-05-14 | 济南大学 | 伏硫西汀自由碱或其药用盐长效缓释制剂及其制备方法 |
| WO2025153747A1 (fr) | 2024-01-17 | 2025-07-24 | Laboratorios Farmacéuticos Rovi, S.A. | Compositions et schémas posologiques d'inhibiteurs d'aromatase améliorés |
| USD1137672S1 (en) | 2024-08-27 | 2026-07-28 | Glaukos Corporation | Drug eluting ocular implant |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5242910A (en) * | 1992-10-13 | 1993-09-07 | The Procter & Gamble Company | Sustained release compositions for treating periodontal disease |
| EP0669128B1 (fr) * | 1992-11-17 | 2000-01-05 | Yoshitomi Pharmaceutical Industries, Ltd. | Microsphere a liberation prolongee contenant un antipshychotique et procede de production |
| US5650173A (en) * | 1993-11-19 | 1997-07-22 | Alkermes Controlled Therapeutics Inc. Ii | Preparation of biodegradable microparticles containing a biologically active agent |
| GB9718986D0 (en) * | 1997-09-09 | 1997-11-12 | Danbiosyst Uk | Controlled release microsphere delivery system |
| WO2002058672A2 (fr) * | 2001-01-26 | 2002-08-01 | Debio Recherche Pharmaceutique S.A. | Microparticules de polymere biodegradable encapsulant une substance biologiquement active et formulations pharmaceutiques a liberation prolongee contenant lesdites particules |
| ES2541908T3 (es) * | 2001-10-10 | 2015-07-28 | Pierre Fabre Medicament | Microesferas biodegradables de liberación prolongada y su procedimiento de preparación |
| TW200719903A (en) * | 2005-04-19 | 2007-06-01 | Combinatorx Inc | Compositions for the treatment of neoplasms |
-
2007
- 2007-10-03 US US12/444,257 patent/US20100098735A1/en not_active Abandoned
- 2007-10-03 CA CA002665101A patent/CA2665101A1/fr not_active Abandoned
- 2007-10-03 BR BRPI0718288-0A2A patent/BRPI0718288A2/pt not_active Application Discontinuation
- 2007-10-03 KR KR1020097009284A patent/KR20090087441A/ko not_active Ceased
- 2007-10-03 RU RU2009116933/15A patent/RU2009116933A/ru not_active Application Discontinuation
- 2007-10-03 CL CL2007002851A patent/CL2007002851A1/es unknown
- 2007-10-03 MX MX2009003735A patent/MX2009003735A/es unknown
- 2007-10-03 AR ARP070104388A patent/AR063120A1/es unknown
- 2007-10-03 CN CNA2007800441089A patent/CN101541313A/zh active Pending
- 2007-10-03 KR KR1020097009289A patent/KR20090094811A/ko not_active Abandoned
- 2007-10-03 WO PCT/IN2007/000454 patent/WO2008041245A2/fr not_active Ceased
- 2007-10-03 MX MX2009003737A patent/MX2009003737A/es not_active Application Discontinuation
- 2007-10-03 CA CA002665105A patent/CA2665105A1/fr not_active Abandoned
- 2007-10-03 AU AU2007303793A patent/AU2007303793A1/en not_active Abandoned
- 2007-10-03 WO PCT/IN2007/000473 patent/WO2008041246A2/fr not_active Ceased
- 2007-10-03 BR BRPI0720346-2A2A patent/BRPI0720346A2/pt not_active IP Right Cessation
- 2007-10-03 JP JP2009531014A patent/JP2010505819A/ja not_active Withdrawn
- 2007-10-03 EP EP07827594A patent/EP2089000A2/fr not_active Withdrawn
- 2007-10-03 JP JP2009531016A patent/JP2010505821A/ja not_active Withdrawn
- 2007-10-03 EP EP07827598A patent/EP2086505A2/fr not_active Withdrawn
- 2007-10-03 US US12/444,197 patent/US20100015195A1/en not_active Abandoned
- 2007-10-03 CN CNA2007800441356A patent/CN101541316A/zh active Pending
- 2007-10-03 AU AU2007303794A patent/AU2007303794A1/en not_active Abandoned
- 2007-10-03 EA EA200970348A patent/EA200970348A1/ru unknown
-
2009
- 2009-04-03 TN TNP2009000124A patent/TN2009000124A1/fr unknown
- 2009-04-03 TN TNP2009000125A patent/TN2009000125A1/fr unknown
- 2009-04-05 IL IL197947A patent/IL197947A0/en unknown
- 2009-04-05 IL IL197946A patent/IL197946A0/en unknown
- 2009-04-27 MA MA31821A patent/MA30814B1/fr unknown
- 2009-04-27 MA MA31824A patent/MA30817B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008041245A2 (fr) | 2008-04-10 |
| IL197947A0 (en) | 2009-12-24 |
| CA2665105A1 (fr) | 2008-04-10 |
| MA30814B1 (fr) | 2009-10-01 |
| AU2007303793A1 (en) | 2008-04-10 |
| RU2009116933A (ru) | 2010-11-10 |
| KR20090087441A (ko) | 2009-08-17 |
| EA200970348A1 (ru) | 2009-10-30 |
| MX2009003737A (es) | 2009-06-16 |
| WO2008041246A2 (fr) | 2008-04-10 |
| KR20090094811A (ko) | 2009-09-08 |
| WO2008041245A3 (fr) | 2008-05-22 |
| BRPI0718288A2 (pt) | 2013-11-19 |
| CN101541313A (zh) | 2009-09-23 |
| JP2010505821A (ja) | 2010-02-25 |
| WO2008041246A3 (fr) | 2008-05-29 |
| IL197946A0 (en) | 2009-12-24 |
| JP2010505819A (ja) | 2010-02-25 |
| BRPI0720346A2 (pt) | 2014-06-24 |
| CN101541316A (zh) | 2009-09-23 |
| US20100015195A1 (en) | 2010-01-21 |
| CA2665101A1 (fr) | 2008-04-10 |
| TN2009000125A1 (en) | 2010-10-18 |
| TN2009000124A1 (en) | 2010-10-18 |
| US20100098735A1 (en) | 2010-04-22 |
| MX2009003735A (es) | 2009-04-22 |
| EP2086505A2 (fr) | 2009-08-12 |
| AU2007303794A1 (en) | 2008-04-10 |
| CL2007002851A1 (es) | 2008-01-18 |
| EP2089000A2 (fr) | 2009-08-19 |
| AR063120A1 (es) | 2008-12-30 |
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