MA32175B1 - Oxadiazoanthracènes pour le traitement du diabète - Google Patents

Oxadiazoanthracènes pour le traitement du diabète

Info

Publication number
MA32175B1
MA32175B1 MA33212A MA33212A MA32175B1 MA 32175 B1 MA32175 B1 MA 32175B1 MA 33212 A MA33212 A MA 33212A MA 33212 A MA33212 A MA 33212A MA 32175 B1 MA32175 B1 MA 32175B1
Authority
MA
Morocco
Prior art keywords
derivatives
diabetes
treatment
oxadiazo
oxadiazoanthracenes
Prior art date
Application number
MA33212A
Other languages
Arabic (ar)
English (en)
Inventor
Adnan M M Mjalli
Dharma Rao Polisetti
Thomas Scott Yokum
Kalpathy Santhosh
Mustafa Guzel
Christopher Behme
Stephen Thomas Davis
Original Assignee
Transtech Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transtech Pharma Inc filed Critical Transtech Pharma Inc
Publication of MA32175B1 publication Critical patent/MA32175B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La présente invention concerne des dérivés de l'oxadiazoanthracène de formule (i) dans laquelle a, b, c, r, r1, r2, r3, r4 et r5 sont tels que décrits dans la description, des compositions pharmaceutiques comprenant les dérivés de l'oxadiazoanthracène, l'utilisation des dérivés de l'oxadiazoanthracène pour la préparation de compositions pharmaceutiques, des procédés de leur utilisation pour le traitement et/ou la prévention de maladies et de troubles tels que le diabète et des intermédiaires utiles pour la préparation des dérivés de l'oxadiazoanthracène de formule (i).
MA33212A 2008-03-07 2010-09-30 Oxadiazoanthracènes pour le traitement du diabète MA32175B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3459908P 2008-03-07 2008-03-07
PCT/US2009/036333 WO2009111700A2 (fr) 2008-03-07 2009-03-06 Oxadiazoanthracènes pour le traitement du diabète

Publications (1)

Publication Number Publication Date
MA32175B1 true MA32175B1 (fr) 2011-03-01

Family

ID=41056666

Family Applications (1)

Application Number Title Priority Date Filing Date
MA33212A MA32175B1 (fr) 2008-03-07 2010-09-30 Oxadiazoanthracènes pour le traitement du diabète

Country Status (17)

Country Link
US (7) US7727983B2 (fr)
EP (1) EP2262364B1 (fr)
JP (1) JP5382952B2 (fr)
KR (1) KR101616737B1 (fr)
CN (1) CN101959405B (fr)
AU (1) AU2009221722B2 (fr)
BR (1) BRPI0910282A2 (fr)
CA (1) CA2716664C (fr)
DK (1) DK2262364T3 (fr)
EA (1) EA018225B1 (fr)
ES (1) ES2567451T3 (fr)
IL (1) IL207570A (fr)
MA (1) MA32175B1 (fr)
MX (1) MX2010009752A (fr)
NZ (1) NZ587343A (fr)
WO (1) WO2009111700A2 (fr)
ZA (1) ZA201006367B (fr)

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TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
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PT2673260T (pt) 2011-02-08 2016-10-24 Pfizer Modulador do recetor de glucagon
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JP7558267B2 (ja) 2019-10-25 2024-09-30 ギリアード サイエンシーズ， インコーポレイテッド Ｇｌｐ－１ｒ調節化合物
JP2023528565A (ja) 2020-04-01 2023-07-05 ハンジョウ ジョンメイ フアドン ファーマシューティカル シーオー．，エルティーディー． Ｇｌｐ－１受容体アゴニストの結晶形ａおよびその調製法
WO2021196951A1 (fr) 2020-04-01 2021-10-07 杭州中美华东制药有限公司 Sel d'acide pharmaceutiquement acceptable de base libre d'agoniste du récepteur glp-1, et son procédé de préparation
TW202144340A (zh) 2020-04-03 2021-12-01 大陸商江蘇恆瑞醫藥股份有限公司 稠合咪唑類衍生物、其製備方法及其在醫藥上的應用
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Also Published As

Publication number Publication date
IL207570A0 (en) 2010-12-30
WO2009111700A2 (fr) 2009-09-11
US20100324033A1 (en) 2010-12-23
JP5382952B2 (ja) 2014-01-08
US20140187769A1 (en) 2014-07-03
IL207570A (en) 2014-03-31
CA2716664C (fr) 2016-10-11
ES2567451T3 (es) 2016-04-22
US20150087640A1 (en) 2015-03-26
US20110039837A1 (en) 2011-02-17
AU2009221722A1 (en) 2009-09-11
US8524708B2 (en) 2013-09-03
US20130317015A1 (en) 2013-11-28
EA201071045A1 (ru) 2011-02-28
US8933222B2 (en) 2015-01-13
BRPI0910282A2 (pt) 2015-09-01
AU2009221722B2 (en) 2014-12-18
CA2716664A1 (fr) 2009-09-11
EP2262364A4 (fr) 2012-04-04
ZA201006367B (en) 2011-05-25
US7906507B2 (en) 2011-03-15
DK2262364T3 (en) 2016-03-21
JP2011513431A (ja) 2011-04-28
EP2262364B1 (fr) 2016-03-02
EP2262364A2 (fr) 2010-12-22
EA018225B1 (ru) 2013-06-28
WO2009111700A3 (fr) 2010-03-04
US9120813B2 (en) 2015-09-01
CN101959405B (zh) 2014-07-02
US8703766B2 (en) 2014-04-22
KR20100131455A (ko) 2010-12-15
US7790714B2 (en) 2010-09-07
MX2010009752A (es) 2010-09-30
KR101616737B1 (ko) 2016-05-02
CN101959405A (zh) 2011-01-26
HK1148435A1 (en) 2011-09-09
US20100197677A1 (en) 2010-08-05
US20090306063A1 (en) 2009-12-10
NZ587343A (en) 2012-05-25
US7727983B2 (en) 2010-06-01

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