MA32969B1 - Compositions pharmaceutiques presentant de remarquables performances et entrainant une excellente adhesion du patient a son traitement - Google Patents
Compositions pharmaceutiques presentant de remarquables performances et entrainant une excellente adhesion du patient a son traitementInfo
- Publication number
- MA32969B1 MA32969B1 MA34019A MA34019A MA32969B1 MA 32969 B1 MA32969 B1 MA 32969B1 MA 34019 A MA34019 A MA 34019A MA 34019 A MA34019 A MA 34019A MA 32969 B1 MA32969 B1 MA 32969B1
- Authority
- MA
- Morocco
- Prior art keywords
- treatment
- pharmaceutical compositions
- remarkable performance
- excellent patient
- patient membership
- Prior art date
Links
- 230000002708 enhancing effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000007906 compression Methods 0.000 abstract 2
- 230000006835 compression Effects 0.000 abstract 2
- KQNPFQTWMSNSAP-UHFFFAOYSA-N isobutyric acid Chemical compound CC(C)C(O)=O KQNPFQTWMSNSAP-UHFFFAOYSA-N 0.000 abstract 2
- -1 4-amino-2-oxo-2H-pyrimidin-1-yl Chemical group 0.000 abstract 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 abstract 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La présente invention concerne de nouvelles formulations de l'ester (2R,3R,4R,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-4-fluoro-2-isobutyryloxyméthyl-4-méthyl-tétrahydro-furan-3-ylique de l'acide isobutyrique et de l'hydroxypropylcellulose, caractérisées par une masse volumique apparente élevée, par une faible taille des particules permettant une meilleure compression et une fluidité améliorée, par une bonne compression et par des profils de dissolution rapides.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14599909P | 2009-01-21 | 2009-01-21 | |
| PCT/EP2010/050182 WO2010084041A2 (fr) | 2009-01-21 | 2010-01-11 | Compositions pharmaceutiques présentant de remarquables performances et entraînant une excellente adhésion du patient à son traitement |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA32969B1 true MA32969B1 (fr) | 2012-01-02 |
Family
ID=42026386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA34019A MA32969B1 (fr) | 2009-01-21 | 2010-01-11 | Compositions pharmaceutiques presentant de remarquables performances et entrainant une excellente adhesion du patient a son traitement |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US8222230B2 (fr) |
| EP (1) | EP2389164B1 (fr) |
| JP (1) | JP5415561B2 (fr) |
| KR (1) | KR101331723B1 (fr) |
| CN (1) | CN102292075B (fr) |
| AR (1) | AR075037A1 (fr) |
| AU (1) | AU2010206224B2 (fr) |
| BR (1) | BRPI1006924A2 (fr) |
| CA (1) | CA2748895C (fr) |
| CL (1) | CL2011001764A1 (fr) |
| CO (1) | CO6440558A2 (fr) |
| DK (1) | DK2389164T3 (fr) |
| EC (1) | ECSP11011191A (fr) |
| ES (1) | ES2513415T3 (fr) |
| IL (1) | IL213804A0 (fr) |
| MA (1) | MA32969B1 (fr) |
| MX (1) | MX2011007771A (fr) |
| NZ (1) | NZ593795A (fr) |
| PE (1) | PE20120020A1 (fr) |
| PL (1) | PL2389164T3 (fr) |
| RU (1) | RU2489153C2 (fr) |
| SG (1) | SG173001A1 (fr) |
| SI (1) | SI2389164T1 (fr) |
| TW (1) | TWI414295B (fr) |
| UA (1) | UA100937C2 (fr) |
| WO (1) | WO2010084041A2 (fr) |
| ZA (1) | ZA201104882B (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201300106A (zh) * | 2010-11-09 | 2013-01-01 | Hoffmann La Roche | 治療hcv感染之醫藥組合物 |
| US10835495B2 (en) | 2012-11-14 | 2020-11-17 | W. R. Grace & Co.-Conn. | Compositions containing a biologically active material and a non-ordered inorganic oxide material and methods of making and using the same |
| DE102013215831A1 (de) * | 2013-08-09 | 2015-02-12 | Beiersdorf Ag | Gelförmiges, alkoholisches Sonnenschutzmittel |
| JP6697402B2 (ja) * | 2015-01-30 | 2020-05-20 | 協和発酵バイオ株式会社 | 機能性物質を高含有する錠剤及びその製造方法 |
| EP3417857B1 (fr) * | 2016-02-19 | 2023-07-19 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Composition pharmaceutique contenant un dérivé d'imidazoline |
| JP6323846B2 (ja) * | 2016-04-07 | 2018-05-16 | 塩野義製薬株式会社 | オピオイドを含有する乱用防止製剤 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA03006514A (es) * | 2001-01-22 | 2004-12-02 | Merck & Co Inc | Derivados de nucleosidos como inhibidores de polimerasa de acido ribonucleico viral dependiente de acido ribonucleico. |
| JP4408340B2 (ja) * | 2002-03-22 | 2010-02-03 | 武田薬品工業株式会社 | 速崩壊性固形製剤 |
| TWI332507B (en) * | 2002-11-19 | 2010-11-01 | Hoffmann La Roche | Antiviral nucleoside derivatives |
| ZA200711048B (en) * | 2005-06-22 | 2009-05-27 | Takeda Pharmaceutical | Tablet containing hardly soluble active incredient |
| JP2008230967A (ja) * | 2005-06-23 | 2008-10-02 | Kowa Co | 医薬組成物 |
| BRPI0619563A2 (pt) * | 2005-12-09 | 2011-10-04 | Pharmasset Inc | nucleosìdeos antivirais |
| EP1962808B1 (fr) * | 2005-12-14 | 2010-09-29 | F. Hoffmann-La Roche AG | Formule de promédicament contre le vhc |
-
2010
- 2010-01-11 PL PL10700233T patent/PL2389164T3/pl unknown
- 2010-01-11 JP JP2011546733A patent/JP5415561B2/ja not_active Expired - Fee Related
- 2010-01-11 UA UAA201110008A patent/UA100937C2/uk unknown
- 2010-01-11 SG SG2011051240A patent/SG173001A1/en unknown
- 2010-01-11 DK DK10700233.9T patent/DK2389164T3/da active
- 2010-01-11 EP EP10700233.9A patent/EP2389164B1/fr active Active
- 2010-01-11 CN CN2010800050195A patent/CN102292075B/zh not_active Expired - Fee Related
- 2010-01-11 ES ES10700233.9T patent/ES2513415T3/es active Active
- 2010-01-11 PE PE2011001307A patent/PE20120020A1/es not_active Application Discontinuation
- 2010-01-11 NZ NZ593795A patent/NZ593795A/xx not_active IP Right Cessation
- 2010-01-11 MA MA34019A patent/MA32969B1/fr unknown
- 2010-01-11 BR BRPI1006924A patent/BRPI1006924A2/pt not_active IP Right Cessation
- 2010-01-11 RU RU2011134713/15A patent/RU2489153C2/ru not_active IP Right Cessation
- 2010-01-11 MX MX2011007771A patent/MX2011007771A/es active IP Right Grant
- 2010-01-11 KR KR1020117019277A patent/KR101331723B1/ko not_active Expired - Fee Related
- 2010-01-11 WO PCT/EP2010/050182 patent/WO2010084041A2/fr not_active Ceased
- 2010-01-11 CA CA2748895A patent/CA2748895C/fr not_active Expired - Fee Related
- 2010-01-11 AU AU2010206224A patent/AU2010206224B2/en not_active Ceased
- 2010-01-11 SI SI201030785T patent/SI2389164T1/sl unknown
- 2010-01-18 TW TW099101246A patent/TWI414295B/zh not_active IP Right Cessation
- 2010-01-18 US US12/689,004 patent/US8222230B2/en not_active Expired - Fee Related
- 2010-01-20 AR ARP100100124A patent/AR075037A1/es unknown
-
2011
- 2011-06-28 IL IL213804A patent/IL213804A0/en unknown
- 2011-06-30 CO CO11082167A patent/CO6440558A2/es not_active Application Discontinuation
- 2011-07-01 ZA ZA2011/04882A patent/ZA201104882B/en unknown
- 2011-07-07 EC EC2011011191A patent/ECSP11011191A/es unknown
- 2011-07-21 CL CL2011001764A patent/CL2011001764A1/es unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA33349B1 (fr) | Compositions pharmaceutiques solides et procedes pour leur production | |
| EA201170289A1 (ru) | Фармацевтические композиции и способы их получения при низкой концентрации примесей | |
| PH12015500301A1 (en) | A novel formulation of diclofenac | |
| MA33044B1 (fr) | Composition pharmaceutique contenant des derives de glucopyranosyl diphenylmethane, sa forme posologique galenique, son procede de preparation et ses utilisations pour une regulation glycemique amelioree chez un patient | |
| MX2011011233A (es) | Una formulacion novedosa de metaxalona. | |
| EA201171279A1 (ru) | Производство инкапсулированных наночастиц с высокой объемной долей | |
| EA201291168A1 (ru) | Фармацевтические композиции и способы их получения | |
| MA34169B1 (fr) | Dérivés d'acide 1-amino-2-cyclopropyléthylboronique | |
| GEP20156366B (en) | Iminothiadiazine dioxide compounds as bace inhibitors, compositions, and their use | |
| EA201500393A1 (ru) | Ингибиторы тирозинкиназы брутона | |
| PE20011268A1 (es) | Composiciones farmaceuticas que comprenden una dispersion de solidos amorfos de [(1s)-bencil-(2r)-hidroxi-3-((3r,4s)-dihidroxi-pirrolidin-1-il)-3-oxipropil]amida del acido 5-cloro-1h-indol-2-carboxilico en un polimero que aumenta la concentracion com | |
| EA201390409A1 (ru) | Составы с низкой дозой панкрелипазы и кишечно-растворимым покрытием | |
| MY159208A (en) | A novel formulation of indomethacin | |
| EA201171281A1 (ru) | Производство инкапсулированных наночастиц в коммерческих масшатабах | |
| PH12016500746A1 (en) | A novel formulation of meloxicam | |
| EA201171088A1 (ru) | Лечение дискинезии при различных расстройствах | |
| EA201200185A1 (ru) | Фармацевтическая композиция для пероральной доставки дииндолилметана | |
| EP2257161A4 (fr) | Inhibiteurs de l'ahcy hydrolase destinés au traitement de l'hyper-homocystéinémie | |
| EA201991341A1 (ru) | Фенитоин для местного применения для лечения периферической нейропатической боли | |
| WO2011115456A3 (fr) | Antagoniste double tnf-α et tweak pour la prophylaxie et le traitement des maladies autoimmunes | |
| RU2014149700A (ru) | Композиции для доставки активных ингредиентов | |
| MX2011007771A (es) | Composiciones farmaceuticas que comprenden un profarmaco inhibidor de la polimerasa del virus de la hepatitis c (hcv). | |
| GB0717442D0 (en) | Compositions and uses thereof | |
| AU2014208310B2 (en) | A Novel Formulation of Diclofenac | |
| MA38974A1 (fr) | Formes galéniques pharmaceutiques contenant du sodium 1-[6-{morpholine-4-yl)pyrimidine-4-yl]-4-(1h-1,2,3- triazol-1-yl)-1h-pyrazol-5-olate |