MA33374B1 - Composition de surfactant reconstitué améliorée contenant des analogues de la protéine b du surfactant (sp-b) et de la protéine c du surfactant (sp-c) - Google Patents
Composition de surfactant reconstitué améliorée contenant des analogues de la protéine b du surfactant (sp-b) et de la protéine c du surfactant (sp-c)Info
- Publication number
- MA33374B1 MA33374B1 MA34471A MA34471A MA33374B1 MA 33374 B1 MA33374 B1 MA 33374B1 MA 34471 A MA34471 A MA 34471A MA 34471 A MA34471 A MA 34471A MA 33374 B1 MA33374 B1 MA 33374B1
- Authority
- MA
- Morocco
- Prior art keywords
- surfactant
- surfactant protein
- protein
- analogues
- composition containing
- Prior art date
Links
- 239000004094 surface-active agent Substances 0.000 title abstract 3
- 101001086862 Homo sapiens Pulmonary surfactant-associated protein B Proteins 0.000 title 2
- 101000612671 Homo sapiens Pulmonary surfactant-associated protein C Proteins 0.000 title 2
- 102100032617 Pulmonary surfactant-associated protein B Human genes 0.000 title 2
- 102100040971 Pulmonary surfactant-associated protein C Human genes 0.000 title 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 abstract 1
- 102000007620 Pulmonary Surfactant-Associated Protein C Human genes 0.000 abstract 1
- 108010007125 Pulmonary Surfactant-Associated Protein C Proteins 0.000 abstract 1
- 208000013616 Respiratory Distress Syndrome Diseases 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 239000003580 lung surfactant Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/395—Alveolar surfactant peptides; Pulmonary surfactant peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0082—Lung surfactant, artificial mucus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- General Preparation And Processing Of Foods (AREA)
- Cosmetics (AREA)
Abstract
LA PRÉSENTE INVENTION A POUR OBJET UN SURFACTANT PULMONAIRE RECONSTITUÉ COMPRENANT UN SUPPORT LIPIDIQUE, UNE COMBINAISON D'UN ANALOGUE POLYPEPTIDIQUE DE LA PROTÉINE DE SURFACTANT NATIVE SP-C AVEC UN ANALOGUE POLYPEPTIDIQUE PARTICULIER DE LA PROTÉINE DE SURFACTANT NATIVE SP-B. LA PRÉSENTE INVENTION CONCERNE ÉGALEMENT LEURS FORMULATIONS PHARMACEUTIQUES ET LEUR UTILISATION POUR LE TRAITEMENT OU LA PROPHYLAXIE DU SYNDROME DE DÉTRESSE RESPIRATOIRE ET D'AUTRES TROUBLES RESPIRATOIRES.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09162052 | 2009-06-05 | ||
| PCT/EP2010/003293 WO2010139442A1 (fr) | 2009-06-05 | 2010-05-31 | Composition de surfactant reconstitué améliorée contenant des analogues de la protéine b du surfactant (sp-b) et de la protéine c du surfactant (sp-c) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA33374B1 true MA33374B1 (fr) | 2012-06-01 |
Family
ID=41055357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA34471A MA33374B1 (fr) | 2009-06-05 | 2010-05-31 | Composition de surfactant reconstitué améliorée contenant des analogues de la protéine b du surfactant (sp-b) et de la protéine c du surfactant (sp-c) |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US8399406B2 (fr) |
| EP (1) | EP2438086B1 (fr) |
| JP (1) | JP5666569B2 (fr) |
| KR (1) | KR101668137B1 (fr) |
| CN (1) | CN102459327B (fr) |
| AR (1) | AR076973A1 (fr) |
| AU (1) | AU2010256066B2 (fr) |
| BR (1) | BRPI1010120B1 (fr) |
| CA (1) | CA2764454C (fr) |
| CL (1) | CL2011003003A1 (fr) |
| CO (1) | CO6470858A2 (fr) |
| CY (1) | CY1118676T1 (fr) |
| DK (1) | DK2438086T3 (fr) |
| EA (1) | EA021163B1 (fr) |
| ES (1) | ES2621974T3 (fr) |
| GE (1) | GEP20135967B (fr) |
| HR (1) | HRP20170445T1 (fr) |
| HU (1) | HUE034053T2 (fr) |
| IL (1) | IL216718A (fr) |
| JO (1) | JO3226B1 (fr) |
| LT (1) | LT2438086T (fr) |
| MA (1) | MA33374B1 (fr) |
| ME (1) | ME01279B (fr) |
| MX (1) | MX2011012951A (fr) |
| MY (1) | MY159464A (fr) |
| NZ (1) | NZ596848A (fr) |
| PE (1) | PE20120541A1 (fr) |
| PL (1) | PL2438086T3 (fr) |
| PT (1) | PT2438086T (fr) |
| SG (1) | SG176305A1 (fr) |
| SI (1) | SI2438086T1 (fr) |
| TN (1) | TN2011000558A1 (fr) |
| TW (1) | TWI457132B (fr) |
| UA (1) | UA103526C2 (fr) |
| WO (1) | WO2010139442A1 (fr) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2170283B1 (fr) | 2007-06-22 | 2019-01-09 | Board of Regents, The University of Texas System | Formation de particules de peptide ou de protéine submicroniques stables par congélation de film mince |
| JP2014514275A (ja) * | 2011-03-10 | 2014-06-19 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | タンパク質ナノ粒子分散系 |
| US9815869B2 (en) | 2012-02-09 | 2017-11-14 | University Of Rochester | SP-B and SP-C peptides, synthetic lung surfactants, and use thereof |
| AR093569A1 (es) | 2012-11-21 | 2015-06-10 | Chiesi Farm Spa | Tensioactivos pulmonares reconstituidos |
| CN104382942A (zh) * | 2014-11-05 | 2015-03-04 | 烟台东诚药业集团股份有限公司 | 一种猪肺表面活性物质混悬液制备新工艺 |
| EP3106090A1 (fr) | 2015-06-15 | 2016-12-21 | CHIESI FARMACEUTICI S.p.A. | Système pour une administration efficace, synchronisée avec la respiration, d'un médicament aux poumons |
| HK1247140A1 (zh) | 2015-04-22 | 2018-09-21 | 奇斯药制品公司 | 用於药物有效地呼吸同步递送到肺部的方法和系统 |
| US11311691B2 (en) | 2015-04-28 | 2022-04-26 | Chiesi Farmaceutici S.P.A | Device for facilitating the administration of a medicament to the lung by a catheter |
| CA3016810C (fr) * | 2016-03-07 | 2024-04-02 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Compositions et procedes pour l'administration d'agonistes de pparv, peptides tensioactifs et phopholipides |
| CN109496159A (zh) | 2016-07-28 | 2019-03-19 | 奇斯药制品公司 | 用于递送雾化药剂的方法和系统 |
| RU2748417C2 (ru) * | 2016-08-24 | 2021-05-25 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Стабильная фармацевтическая композиция, включающая восстановленную композицию легочного сурфактанта |
| WO2018077623A1 (fr) | 2016-10-26 | 2018-05-03 | Chiesi Farmaceutici S.P.A. | Dispositif permettant de faciliter l'administration d'un médicament aux poumons par l'intermédiaire d'un cathéter |
| KR102470549B1 (ko) * | 2016-12-22 | 2022-11-25 | 키에시 파르마슈티시 엣스. 피. 에이. | 발달하는 bpd의 치료를 위한 폐 계면활성제 및 스테로이드를 포함하는 치료 조합물 |
| TW201927286A (zh) | 2017-12-15 | 2019-07-16 | 義大利商凱西製藥公司 | 用於噴霧投藥之包含肺表面張力素的藥學調配物 |
| WO2019115771A1 (fr) | 2017-12-15 | 2019-06-20 | Pari Pharma Gmbh | Système de nébuliseur, système de maintien, combinaison comprenant un système de nébuliseur et un système de maintien, et procédé d'administration d'aérosol |
| MX2020011127A (es) | 2018-04-23 | 2021-01-15 | Chiesi Farm Spa | Combinacion terapeutica que comprende agente tensioactivo pulmonar y esteroide para la profilaxis de displasia broncopulmonar (bpd). |
| EP3666315A1 (fr) | 2018-12-14 | 2020-06-17 | PARI Pharma GmbH | Dispositif d'administration d'aérosol et procédé de fonctionnement du dispositif d'administration d'aérosol |
| EP3666316A1 (fr) | 2018-12-14 | 2020-06-17 | PARI Pharma GmbH | Dispositif d'administration d'aérosol et procédé pour faire fonctionner un dispositif d'administration d'aérosol |
| EP3843105A1 (fr) | 2019-12-23 | 2021-06-30 | PARI Pharma GmbH | Dispositif de commande pour système nébuliseur d'aérosol |
| EP4097128A1 (fr) | 2020-01-28 | 2022-12-07 | Chiesi Farmaceutici S.p.A. | Polypeptides ayant des propriétés améliorées |
| AR126368A1 (es) | 2021-07-05 | 2023-10-11 | Chiesi Farm Spa | Proceso para la preparación de un tensioactivo pulmonar |
| EP4411745A1 (fr) | 2023-02-01 | 2024-08-07 | Pari Medical Holding GmbH | Procédé d'évaluation médicale, nébuliseur d'aérosol et système d'évaluation médicale |
| EP4464236A1 (fr) | 2023-05-15 | 2024-11-20 | Pari Medical Holding GmbH | Procédé de fonctionnement d'un dispositif d'inhalation, dispositif d'inhalation et système de dispositif d'inhalation pour fournir une rétroaction de processus d'inhalation |
| EP4464354A1 (fr) | 2023-05-15 | 2024-11-20 | Pari Medical Holding GmbH | Procédé de fonctionnement d'un dispositif d'inhalation, dispositif d'inhalation et système de dispositif d'inhalation pour fournir un processus d'inhalation/guidage de respiration |
| WO2025024609A1 (fr) * | 2023-07-25 | 2025-01-30 | Biosuperior Technology, Inc. | Polypeptides pour compositions de tensioactifs pulmonaires |
| WO2025245275A1 (fr) * | 2024-05-21 | 2025-11-27 | Molecular Express, Inc. | Préparations tensioactives pour administration pulmonaire, et leurs procédés de préparation et leurs méthodes d'utilisation |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000076535A1 (fr) | 1999-06-11 | 2000-12-21 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Preparation pharmaceutique contenant des modifications de la proteine b du surfactant (sp-b) et de la proteine c du surfactant (sp-c) |
| ITMI20021058A1 (it) * | 2002-05-17 | 2003-11-17 | Chiesi Farma Spa | Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito |
| EP1481665A1 (fr) * | 2003-05-30 | 2004-12-01 | CHIESI FARMACEUTICI S.p.A. | Nouveaux mélanges lipidiques pour tensioactifs synthétiques |
| CA2619079C (fr) * | 2005-05-11 | 2013-08-06 | Yamasa Corporation | Procede de stabilisation d'une proteine surfactante pulmonaire |
| CA2658478C (fr) | 2006-07-20 | 2018-02-13 | University Of Rochester | Tensioactif pulmonaire synthetique et utilisation associee |
| GEP20125531B (en) * | 2006-10-13 | 2012-05-25 | Chiesi Farma Spa | Reconstituted surfactants having improved properties |
| EP1997502A1 (fr) * | 2007-06-01 | 2008-12-03 | CHIESI FARMACEUTICI S.p.A. | Agents tensioactifs reconstitués dotés de propriétés améliorées |
-
2010
- 2010-05-27 US US12/788,480 patent/US8399406B2/en active Active
- 2010-05-31 PT PT107247082T patent/PT2438086T/pt unknown
- 2010-05-31 NZ NZ596848A patent/NZ596848A/xx unknown
- 2010-05-31 MY MYPI2011005866A patent/MY159464A/en unknown
- 2010-05-31 PL PL10724708T patent/PL2438086T3/pl unknown
- 2010-05-31 JP JP2012513503A patent/JP5666569B2/ja active Active
- 2010-05-31 MX MX2011012951A patent/MX2011012951A/es active IP Right Grant
- 2010-05-31 EP EP10724708.2A patent/EP2438086B1/fr active Active
- 2010-05-31 WO PCT/EP2010/003293 patent/WO2010139442A1/fr not_active Ceased
- 2010-05-31 AU AU2010256066A patent/AU2010256066B2/en active Active
- 2010-05-31 MA MA34471A patent/MA33374B1/fr unknown
- 2010-05-31 ME MEP-2011-197A patent/ME01279B/fr unknown
- 2010-05-31 SG SG2011089299A patent/SG176305A1/en unknown
- 2010-05-31 PE PE2011002046A patent/PE20120541A1/es active IP Right Grant
- 2010-05-31 HR HRP20170445TT patent/HRP20170445T1/hr unknown
- 2010-05-31 CN CN201080024545.6A patent/CN102459327B/zh active Active
- 2010-05-31 BR BRPI1010120-9A patent/BRPI1010120B1/pt active IP Right Grant
- 2010-05-31 EA EA201190292A patent/EA021163B1/ru unknown
- 2010-05-31 LT LTEP10724708.2T patent/LT2438086T/lt unknown
- 2010-05-31 CA CA2764454A patent/CA2764454C/fr active Active
- 2010-05-31 ES ES10724708.2T patent/ES2621974T3/es active Active
- 2010-05-31 DK DK10724708.2T patent/DK2438086T3/en active
- 2010-05-31 GE GEAP201012486A patent/GEP20135967B/en unknown
- 2010-05-31 HU HUE10724708A patent/HUE034053T2/en unknown
- 2010-05-31 UA UAA201114285A patent/UA103526C2/ru unknown
- 2010-05-31 KR KR1020117028394A patent/KR101668137B1/ko active Active
- 2010-05-31 SI SI201031433A patent/SI2438086T1/sl unknown
- 2010-06-03 JO JOP/2010/0185A patent/JO3226B1/ar active
- 2010-06-03 TW TW099117884A patent/TWI457132B/zh active
- 2010-06-03 AR ARP100101970A patent/AR076973A1/es not_active Application Discontinuation
-
2011
- 2011-11-04 TN TNP2011000558A patent/TN2011000558A1/en unknown
- 2011-11-25 CL CL2011003003A patent/CL2011003003A1/es unknown
- 2011-12-01 IL IL216718A patent/IL216718A/en active IP Right Grant
- 2011-12-02 CO CO11166483A patent/CO6470858A2/es active IP Right Grant
-
2017
- 2017-02-24 CY CY20171100262T patent/CY1118676T1/el unknown
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