MA33743B1 - Compositions comprenant du tramadol et du célécoxib dans le traitement de la douleur - Google Patents
Compositions comprenant du tramadol et du célécoxib dans le traitement de la douleurInfo
- Publication number
- MA33743B1 MA33743B1 MA34860A MA34860A MA33743B1 MA 33743 B1 MA33743 B1 MA 33743B1 MA 34860 A MA34860 A MA 34860A MA 34860 A MA34860 A MA 34860A MA 33743 B1 MA33743 B1 MA 33743B1
- Authority
- MA
- Morocco
- Prior art keywords
- tramadol
- celecoxib
- treatment
- pain
- combinations
- Prior art date
Links
- TVYLLZQTGLZFBW-ZBFHGGJFSA-N (R,R)-tramadol Chemical compound COC1=CC=CC([C@]2(O)[C@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-ZBFHGGJFSA-N 0.000 title abstract 2
- RZEKVGVHFLEQIL-UHFFFAOYSA-N celecoxib Chemical compound C1=CC(C)=CC=C1C1=CC(C(F)(F)F)=NN1C1=CC=C(S(N)(=O)=O)C=C1 RZEKVGVHFLEQIL-UHFFFAOYSA-N 0.000 title abstract 2
- 229960000590 celecoxib Drugs 0.000 title abstract 2
- 229960004380 tramadol Drugs 0.000 title abstract 2
- TVYLLZQTGLZFBW-GOEBONIOSA-N tramadol Natural products COC1=CC=CC([C@@]2(O)[C@@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-GOEBONIOSA-N 0.000 title abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
- A61K31/015—Hydrocarbons carbocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La présente invention concerne des compositions pharmaceutiques comprenant du tramadol et du célécoxib et leurs utilisations en tant que médicaments ou analgésiques, plus particulièrement pour le traitement de fortes douleurs afin de modérer celles-ci au moyen d'un composant pour l'inflammation.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09384004A EP2311446A1 (fr) | 2009-10-16 | 2009-10-16 | Compositions comprenant du Tramadol et du Célécoxib pour le traitement de la douleur |
| PCT/EP2010/006317 WO2011045075A1 (fr) | 2009-10-16 | 2010-10-15 | Compositions comprenant du tramadol et du célécoxib dans le traitement de la douleur |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA33743B1 true MA33743B1 (fr) | 2012-11-01 |
Family
ID=41566149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA34860A MA33743B1 (fr) | 2009-10-16 | 2012-05-11 | Compositions comprenant du tramadol et du célécoxib dans le traitement de la douleur |
Country Status (33)
| Country | Link |
|---|---|
| US (3) | US8569271B2 (fr) |
| EP (3) | EP2311446A1 (fr) |
| JP (2) | JP5579858B2 (fr) |
| KR (1) | KR101688996B1 (fr) |
| CN (2) | CN107050006A (fr) |
| AR (1) | AR078653A1 (fr) |
| AU (1) | AU2010306114B2 (fr) |
| BR (1) | BR112012005044B8 (fr) |
| CA (1) | CA2771651C (fr) |
| CO (1) | CO6511249A2 (fr) |
| CY (1) | CY1114960T1 (fr) |
| DK (1) | DK2488170T3 (fr) |
| EC (1) | ECSP12011735A (fr) |
| ES (1) | ES2450615T3 (fr) |
| HR (1) | HRP20140157T1 (fr) |
| IL (1) | IL218096A (fr) |
| IN (1) | IN2012DN01434A (fr) |
| MA (1) | MA33743B1 (fr) |
| MX (1) | MX2012003051A (fr) |
| MY (1) | MY156275A (fr) |
| NZ (1) | NZ598361A (fr) |
| PL (1) | PL2488170T3 (fr) |
| PT (1) | PT2488170E (fr) |
| RS (1) | RS53202B (fr) |
| RU (2) | RU2707752C2 (fr) |
| SG (1) | SG178833A1 (fr) |
| SI (1) | SI2488170T1 (fr) |
| SM (1) | SMT201400035B (fr) |
| TN (1) | TN2012000059A1 (fr) |
| TW (1) | TWI466668B (fr) |
| UA (1) | UA108213C2 (fr) |
| WO (1) | WO2011045075A1 (fr) |
| ZA (1) | ZA201202151B (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2177215A1 (fr) | 2008-10-17 | 2010-04-21 | Laboratorios Del. Dr. Esteve, S.A. | Co-cristaux de tramadol et NSAID |
| US8746719B2 (en) * | 2010-08-03 | 2014-06-10 | Polaris Industries Inc. | Side-by-side vehicle |
| WO2012136969A2 (fr) * | 2011-04-05 | 2012-10-11 | Anant Sharma | Traitements ophtalmiques |
| PL2811833T3 (pl) | 2012-02-06 | 2016-05-31 | William L Pridgen | Połączenie famcyklowiru i celekoksybu na czynnościowe zespoły somatyczne |
| WO2016116942A1 (fr) | 2015-01-20 | 2016-07-28 | Anlon Chemical Research Organization | Nouveaux composés pharmaceutiques comprenant du ticagrélor avec des sels d'aspirine |
| RU2708254C2 (ru) * | 2015-05-28 | 2019-12-05 | Др. Редди'С Лабораториз Лтд. | Пероральная композиция целекоксиба для лечения боли |
| KR101710792B1 (ko) * | 2015-07-14 | 2017-02-28 | 주식회사 유영제약 | 세레콕시브 및 트라마돌을 함유하는 약제학적 조성물 |
| MX2016006464A (es) * | 2016-05-18 | 2017-11-17 | Laboratorios Liomont S A De C V | Composicion farmaceutica de una combinacion de clorhidrato de tramadol-etoricoxib para el tratamiento del dolor. |
| BR112018074486A2 (pt) * | 2016-05-27 | 2019-05-28 | Dr Reddy´S Laboratories Ltd | composição oral de celecoxib para tratamento da dor |
| WO2018186650A2 (fr) * | 2017-04-03 | 2018-10-11 | 주식회사 킴스헬스케어 | Comprimé composite double pour administration orale contenant du tramadol et du célécoxib |
| US20200323780A1 (en) | 2017-04-03 | 2020-10-15 | Kims Healthcare Co., Ltd. | Bilayer combination tablet for oral administration containing tramadol and celecoxib |
| KR102631399B1 (ko) | 2018-03-30 | 2024-02-01 | 씨지인바이츠 주식회사 | 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물 |
| BR112021020893A2 (pt) * | 2019-05-14 | 2022-04-19 | Esteve Pharmaceuticals Sa | Uso de cocristais de tramadol e celecoxib para o tratamento de dor, ao mesmo tempo que reduzindo a suscetibilidade a abuso do tramadol |
| CN112007024A (zh) * | 2019-05-28 | 2020-12-01 | 江苏恒瑞医药股份有限公司 | 艾瑞昔布与曲马多联合在制备治疗疼痛的药物中的用途 |
| CN114681470A (zh) | 2020-12-28 | 2022-07-01 | 雷迪博士实验室有限公司 | 治疗疼痛的方法 |
| WO2025125888A1 (fr) * | 2023-12-15 | 2025-06-19 | Centro De Investigación Y De Estudios Avanzados Del I.P.N. | Compositions d'aripiprazole et de tramadol ayant des effets de potentialisation et une efficacité analgésique élevée utiles pour le traitement de la douleur neuropathique |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU661723B2 (en) | 1991-10-30 | 1995-08-03 | Mcneilab, Inc. | Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug |
| US5516803A (en) | 1991-10-30 | 1996-05-14 | Mcneilab, Inc. | Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug |
| RS49982B (sr) * | 1997-09-17 | 2008-09-29 | Euro-Celtique S.A., | Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2 |
| MXPA01008903A (es) * | 1999-03-01 | 2003-07-21 | Johnson & Jonhson | Composicion que comprende un material de tramadol y un farmaco inhibidor de cox-2 selectivo. |
| DE19927688A1 (de) | 1999-06-17 | 2000-12-21 | Gruenenthal Gmbh | Mehrschichttablette zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac |
| US7790905B2 (en) * | 2002-02-15 | 2010-09-07 | Mcneil-Ppc, Inc. | Pharmaceutical propylene glycol solvate compositions |
| NZ535500A (en) * | 2002-02-19 | 2006-09-29 | Adcock Ingram Ltd | Pharmaceutical combinations of COX-2 inhibitors i.e. meloxicam, opiates i.e. codeine and centrally acting cox inhibitors i.e. paracetamol |
| US20080031950A1 (en) * | 2007-04-27 | 2008-02-07 | Nectid Inc. | Novel anelgesic combination |
| CN104817501B (zh) * | 2009-10-16 | 2017-09-22 | 埃斯蒂文博士实验室股份有限公司 | 曲马多与昔布类的共晶体 |
| EP2392319A1 (fr) * | 2010-06-04 | 2011-12-07 | Laboratorios Del. Dr. Esteve, S.A. | Composition pharmaceutique contenant des co-cristaux de tramadol et d'un coxib |
-
2009
- 2009-10-16 EP EP09384004A patent/EP2311446A1/fr not_active Withdrawn
-
2010
- 2010-10-14 TW TW99134996A patent/TWI466668B/zh active
- 2010-10-15 CN CN201611195215.9A patent/CN107050006A/zh active Pending
- 2010-10-15 RU RU2016125895A patent/RU2707752C2/ru active
- 2010-10-15 KR KR1020127009600A patent/KR101688996B1/ko not_active Ceased
- 2010-10-15 HR HRP20140157AT patent/HRP20140157T1/hr unknown
- 2010-10-15 SI SI201030545T patent/SI2488170T1/sl unknown
- 2010-10-15 MY MYPI2012000614A patent/MY156275A/en unknown
- 2010-10-15 CA CA2771651A patent/CA2771651C/fr active Active
- 2010-10-15 MX MX2012003051A patent/MX2012003051A/es active IP Right Grant
- 2010-10-15 SG SG2012010898A patent/SG178833A1/en unknown
- 2010-10-15 EP EP10765762.9A patent/EP2488170B1/fr active Active
- 2010-10-15 BR BR112012005044A patent/BR112012005044B8/pt active IP Right Grant
- 2010-10-15 EP EP13005822.5A patent/EP2737898A1/fr not_active Withdrawn
- 2010-10-15 JP JP2012533530A patent/JP5579858B2/ja active Active
- 2010-10-15 IN IN1434DEN2012 patent/IN2012DN01434A/en unknown
- 2010-10-15 AU AU2010306114A patent/AU2010306114B2/en active Active
- 2010-10-15 ES ES10765762.9T patent/ES2450615T3/es active Active
- 2010-10-15 AR ARP100103776A patent/AR078653A1/es not_active Application Discontinuation
- 2010-10-15 US US13/394,995 patent/US8569271B2/en active Active
- 2010-10-15 RU RU2012120087/15A patent/RU2012120087A/ru unknown
- 2010-10-15 WO PCT/EP2010/006317 patent/WO2011045075A1/fr not_active Ceased
- 2010-10-15 UA UAA201205897A patent/UA108213C2/uk unknown
- 2010-10-15 RS RS20140100A patent/RS53202B/sr unknown
- 2010-10-15 PT PT107657629T patent/PT2488170E/pt unknown
- 2010-10-15 PL PL10765762T patent/PL2488170T3/pl unknown
- 2010-10-15 DK DK10765762.9T patent/DK2488170T3/en active
- 2010-10-15 NZ NZ598361A patent/NZ598361A/en unknown
- 2010-10-15 CN CN2010800463605A patent/CN102573824A/zh active Pending
-
2012
- 2012-02-10 TN TNP2012000059A patent/TN2012000059A1/en unknown
- 2012-02-14 IL IL218096A patent/IL218096A/en active IP Right Grant
- 2012-03-16 CO CO12046133A patent/CO6511249A2/es active IP Right Grant
- 2012-03-19 EC ECSP12011735 patent/ECSP12011735A/es unknown
- 2012-03-23 ZA ZA2012/02151A patent/ZA201202151B/en unknown
- 2012-05-11 MA MA34860A patent/MA33743B1/fr unknown
-
2013
- 2013-09-25 US US14/036,828 patent/US20140024622A1/en not_active Abandoned
-
2014
- 2014-03-10 CY CY20141100195T patent/CY1114960T1/el unknown
- 2014-03-20 SM SM201400035T patent/SMT201400035B/xx unknown
- 2014-07-09 JP JP2014141720A patent/JP2014221797A/ja not_active Withdrawn
-
2015
- 2015-02-04 US US14/613,475 patent/US20150150889A1/en not_active Abandoned
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