MA32397B1 - Agonistes mixtes basés sur gip destinés au traitement de troubles métaboliques et de l'obésité - Google Patents

Agonistes mixtes basés sur gip destinés au traitement de troubles métaboliques et de l'obésité

Info

Publication number
MA32397B1
MA32397B1 MA33430A MA33430A MA32397B1 MA 32397 B1 MA32397 B1 MA 32397B1 MA 33430 A MA33430 A MA 33430A MA 33430 A MA33430 A MA 33430A MA 32397 B1 MA32397 B1 MA 32397B1
Authority
MA
Morocco
Prior art keywords
gip
obesity
treatment
metabolic disorders
based mixed
Prior art date
Application number
MA33430A
Other languages
Arabic (ar)
English (en)
Inventor
Richard D Dimarchi
Ma Tao
Original Assignee
Univ Indiana Res & Tech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41570802&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA32397(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Indiana Res & Tech Corp filed Critical Univ Indiana Res & Tech Corp
Publication of MA32397B1 publication Critical patent/MA32397B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention concerne des peptides de glucagon qui présentent une activité agoniste de GIP outre une activité du glucagon et/ou de GLP I. La présente invention concerne également des compositions pharmaceutiques comprenant ces peptides de glucagon et des procédés thérapeutiques d'utilisation de ces peptides.
MA33430A 2008-06-17 2010-12-15 Agonistes mixtes basés sur gip destinés au traitement de troubles métaboliques et de l'obésité MA32397B1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7327408P 2008-06-17 2008-06-17
US7817108P 2008-07-03 2008-07-03
US9044808P 2008-08-20 2008-08-20
US15134909P 2009-02-10 2009-02-10
PCT/US2009/047447 WO2010011439A2 (fr) 2008-06-17 2009-06-16 Agonistes mixtes basés sur gip destinés au traitement de troubles métaboliques et de l’obésité

Publications (1)

Publication Number Publication Date
MA32397B1 true MA32397B1 (fr) 2011-06-01

Family

ID=41570802

Family Applications (1)

Application Number Title Priority Date Filing Date
MA33430A MA32397B1 (fr) 2008-06-17 2010-12-15 Agonistes mixtes basés sur gip destinés au traitement de troubles métaboliques et de l'obésité

Country Status (27)

Country Link
US (2) US9062124B2 (fr)
EP (2) EP2300035B1 (fr)
JP (2) JP6108659B2 (fr)
KR (1) KR20110040760A (fr)
CN (2) CN104945500B (fr)
AR (1) AR072159A1 (fr)
AU (1) AU2009274425B2 (fr)
BR (1) BRPI0915282A2 (fr)
CA (1) CA2729296A1 (fr)
CL (1) CL2009001425A1 (fr)
CO (1) CO6280539A2 (fr)
CR (1) CR11849A (fr)
DK (1) DK2300035T3 (fr)
EA (1) EA020326B9 (fr)
EC (1) ECSP10010684A (fr)
ES (2) ES2558842T3 (fr)
HU (1) HUE028072T2 (fr)
IL (1) IL209666A (fr)
MA (1) MA32397B1 (fr)
MX (1) MX2010013453A (fr)
NZ (2) NZ603445A (fr)
PE (1) PE20100056A1 (fr)
PL (1) PL2300035T3 (fr)
SG (1) SG192405A1 (fr)
TW (1) TWI474835B (fr)
WO (1) WO2010011439A2 (fr)
ZA (1) ZA201008807B (fr)

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* Cited by examiner, † Cited by third party
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AU2009274425B2 (en) 2014-05-15
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JP2011524420A (ja) 2011-09-01
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CR11849A (es) 2011-07-18
ES2650038T3 (es) 2018-01-16
ZA201008807B (en) 2011-09-28
CO6280539A2 (es) 2011-05-20
CA2729296A1 (fr) 2010-01-28
US20150322130A1 (en) 2015-11-12
NZ603445A (en) 2014-03-28
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US9062124B2 (en) 2015-06-23
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SG192405A1 (en) 2013-08-30
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WO2010011439A2 (fr) 2010-01-28
MX2010013453A (es) 2011-01-21
CL2009001425A1 (es) 2010-04-30
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IL209666A (en) 2015-02-26
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AU2009274425A1 (en) 2010-01-28
DK2300035T3 (en) 2015-11-16
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