MA34176B1 - Composition pharmaceutique d'ibuprofène pour injection - Google Patents

Composition pharmaceutique d'ibuprofène pour injection

Info

Publication number
MA34176B1
MA34176B1 MA35330A MA35330A MA34176B1 MA 34176 B1 MA34176 B1 MA 34176B1 MA 35330 A MA35330 A MA 35330A MA 35330 A MA35330 A MA 35330A MA 34176 B1 MA34176 B1 MA 34176B1
Authority
MA
Morocco
Prior art keywords
ibuprofen
injection
pharmaceutical composition
containers
autoclave
Prior art date
Application number
MA35330A
Other languages
English (en)
Inventor
Andechaga Ignacio Ortuzar
Gutierrez Mario Ortuzar
Original Assignee
Spain Pharma S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43589415&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA34176(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Spain Pharma S A filed Critical Spain Pharma S A
Publication of MA34176B1 publication Critical patent/MA34176B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention sur une composition pharmaceutique d'ibuprofène pour injection qui comprend une solution aqueuse d'ibuprofène et de trométamol. Ces compositions présentent une perte minimale de principe actif et une augmentation acceptable d'impuretés après stérilisation en autoclave, des propriétés qui ont été prouvées dans divers types de récipients, tels que des récipients en matières plastiques telles que le polypropylène, le PVC et le polyéthylène, ainsi que dans des récipients en verre. Ces compositions, après avoir subi une stérilisation en autoclave, sont encore conformes aux spécifications techniques s'y rapportant de la pharmacopée européenne et de la pharmacopée US.
MA35330A 2010-05-18 2011-05-18 Composition pharmaceutique d'ibuprofène pour injection MA34176B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/ES2010/070330 WO2011144766A1 (fr) 2010-05-18 2010-05-18 Composition pharmaceutique à base d'ibuprofène à injecter
PCT/EP2011/058087 WO2011144677A1 (fr) 2010-05-18 2011-05-18 Composition pharmaceutique d'ibuprofène pour injection

Publications (1)

Publication Number Publication Date
MA34176B1 true MA34176B1 (fr) 2013-04-03

Family

ID=43589415

Family Applications (1)

Application Number Title Priority Date Filing Date
MA35330A MA34176B1 (fr) 2010-05-18 2011-05-18 Composition pharmaceutique d'ibuprofène pour injection

Country Status (35)

Country Link
US (1) US9114165B2 (fr)
EP (1) EP2571488B2 (fr)
JP (1) JP6018048B2 (fr)
KR (1) KR101770808B1 (fr)
CN (1) CN102892410B (fr)
AU (1) AU2011254583B2 (fr)
BR (1) BR112012029171B1 (fr)
CA (1) CA2798575C (fr)
CL (1) CL2012003119A1 (fr)
CO (1) CO6650419A2 (fr)
CR (1) CR20120559A (fr)
CY (1) CY1115394T1 (fr)
DK (1) DK2571488T4 (fr)
EC (1) ECSP12012274A (fr)
ES (1) ES2478491T5 (fr)
HR (1) HRP20140622T4 (fr)
IL (1) IL222497A0 (fr)
MA (1) MA34176B1 (fr)
ME (1) ME01834B (fr)
MX (1) MX2012013402A (fr)
MY (1) MY160302A (fr)
NZ (1) NZ602957A (fr)
PE (1) PE20130374A1 (fr)
PH (1) PH12012502274A1 (fr)
PL (1) PL2571488T5 (fr)
PT (1) PT2571488E (fr)
RS (1) RS53408B2 (fr)
RU (1) RU2012154628A (fr)
SG (1) SG185061A1 (fr)
SI (1) SI2571488T2 (fr)
SM (1) SMT201400103B (fr)
TN (1) TN2012000487A1 (fr)
UA (1) UA103290C2 (fr)
WO (2) WO2011144766A1 (fr)
ZA (1) ZA201207948B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9072710B2 (en) * 2012-03-16 2015-07-07 Cumberland Pharmaceuticals Inc. Injectable ibuprofen formulation
CN104323988A (zh) * 2014-11-27 2015-02-04 北京蓝丹医药科技有限公司 一种用于注射的右旋布洛芬药物组合物
CN105055389B (zh) * 2015-08-03 2018-08-10 北京蓝丹医药科技有限公司 一种用于早产儿先天性心脏病的布洛芬药物组合物
CN105997901A (zh) * 2016-07-27 2016-10-12 济南东方开元医药新技术有限公司 小儿注射用布洛芬氨丁三醇冻干粉针组合物及制备方法
EP3893840B1 (fr) * 2018-12-14 2025-07-09 Fresenius Kabi Austria GmbH Compositions pharmaceutiques pour administration parentérale comprenant de l'ibuprofène et tampon de phosphate
CN112526013B (zh) * 2020-11-20 2022-09-06 人福普克药业（武汉）有限公司 超高液相色谱法检测布洛芬药物中有关物质浓度方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19912436A1 (de) * 1999-03-19 2000-09-21 Merckle Gmbh Ibuprofen-Lösung
US20040132823A1 (en) 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
DE60114249T2 (de) 2001-11-02 2006-05-18 Cumberland Pharmaceuticals Inc., Nashville Pharmazeutische zusammensetzung mit 2-(4-isobutylphenyl) propionsäure
ITMI20040235A1 (it) 2004-02-13 2004-05-13 Therapicon Srl Preparazione farmaceutica per il cavo orale

Also Published As

Publication number Publication date
US20130231390A1 (en) 2013-09-05
ZA201207948B (en) 2013-06-26
WO2011144766A1 (fr) 2011-11-24
AU2011254583A1 (en) 2012-11-08
JP6018048B2 (ja) 2016-11-02
EP2571488A1 (fr) 2013-03-27
CL2012003119A1 (es) 2013-06-07
EP2571488B1 (fr) 2014-06-18
PT2571488E (pt) 2014-07-25
KR101770808B1 (ko) 2017-08-23
PL2571488T3 (pl) 2014-12-31
EP2571488B2 (fr) 2017-07-26
HRP20140622T1 (en) 2014-09-26
HRP20140622T4 (hr) 2017-10-06
SI2571488T1 (sl) 2014-09-30
ME01834B (me) 2014-12-20
DK2571488T3 (da) 2014-07-14
ECSP12012274A (es) 2013-02-28
AU2011254583B2 (en) 2014-04-10
IL222497A0 (en) 2012-12-31
SI2571488T2 (sl) 2017-09-29
CY1115394T1 (el) 2017-01-04
PL2571488T5 (pl) 2018-07-31
BR112012029171B1 (pt) 2021-05-25
JP2013529205A (ja) 2013-07-18
HK1177424A1 (en) 2013-08-23
BR112012029171A2 (pt) 2017-07-18
SMT201400103B (it) 2014-09-08
WO2011144677A1 (fr) 2011-11-24
CA2798575C (fr) 2018-08-28
RS53408B (sr) 2014-10-31
ES2478491T3 (es) 2014-07-22
RS53408B2 (sr) 2018-06-29
ES2478491T5 (es) 2017-11-21
TN2012000487A1 (en) 2014-04-01
MY160302A (en) 2017-02-28
DK2571488T4 (en) 2017-08-28
US9114165B2 (en) 2015-08-25
KR20130109007A (ko) 2013-10-07
SG185061A1 (en) 2012-12-28
PH12012502274A1 (en) 2013-02-04
PE20130374A1 (es) 2013-03-30
CO6650419A2 (es) 2013-04-15
CR20120559A (es) 2013-02-15
CA2798575A1 (fr) 2011-11-24
CN102892410A (zh) 2013-01-23
CN102892410B (zh) 2014-12-10
MX2012013402A (es) 2013-01-17
RU2012154628A (ru) 2014-06-27
UA103290C2 (ru) 2013-09-25
NZ602957A (en) 2014-09-26

Similar Documents

Publication Publication Date Title
MA34176B1 (fr) Composition pharmaceutique d'ibuprofène pour injection
WO2007144770A3 (fr) Bactérie
EA201290498A1 (ru) Терапевтические полимерные наночастицы, включающие эпотилон, и способы их получения и применения
NZ591146A (en) Composition comprising mesenchymal stem cell aggregates wherein the D90 of said aggregates is less than 150 micomills
MA40571A (fr) Composition comprenant un melange d'extraits vegetaux ou un melange de molecules contenues dans ces vegetaux et utilisation pour agir sur le metabolisme glucidique et/ou lipidique
MX2016006147A (es) Suplemento alimenticio.
CL2009000879A1 (es) Metodo para fabricar un producto en un biorreactor que comprende cultivar microorganismos que son adaptados o mutagenizados para que exhiban por lo menos un 150% de tolerancia al producto; sistema para fabricar un producto; biorreactor.
EP2392579A4 (fr) Dérivé d'acide hyaluronique polysulfaté de faible masse moléculaire et médicament le contenant
WO2008089268A3 (fr) Méthodes et compositions destinées au traitement de troubles associés à une infection et/ou à une inflammation
EP4467160A3 (fr) Formulations liquides stabilisées et lyophilisées d'adamts13
NZ705384A (en) Composition for treating hyperlipidemia comprising oxyntomodulin derivative
MX350088B (es) Composicion farmaceutica estable y metodos de uso de la misma.
MA33220B1 (fr) Composition pharmaceutique a proprietes anti-inflammatoires
MX362168B (es) Composiciones estables que comprenden tiabendazol y fungicidas que contienen yodo.
IN2015DN02751A (fr)
BR112017014649A2 (pt) ?isolado intestinal humano, e, composição?
MX2017007675A (es) Composiciones de polietileno con propiedades opticas mejoradas.
BR112014010642A2 (pt) polinucleotídeos, polipeptídeos e métodos para melhorar a fotoassimilação em plantas
MX2010005270A (es) Proceso de acido isoftalico simplificado para modificar pet.
WO2016033572A8 (fr) Procédé pour renforcer les numérations viables de ferments lactiques, et compositions utiles de ce procédé
BRPI1008802A2 (pt) composição, vetor e formulação farmacêutica para o uso na prevenção ou tratamento de alergia a pólen de grama por tolerização, produto, e, método in vitro para determinar se as células t reconhecem uma composição
MX390196B (es) Metodo para fabricar una composicion que comprende un anestesico local, un heparinoide y un regulador de ph.
EP4282972A3 (fr) Production d'acides gras à chaîne ramifiée et de leurs dérivés dans des cellules microbiennes recombinantes
MX2012007587A (es) Composiciones nutricionales que comprenden hojuelas de frutas que incluyen acido docosahexaenoico.
PT2477503E (pt) Processo de preparação de um produto lácteo pasteurizado e fermentado, suplementado com cálcio e vitamina d