MA34832B1 - Compositions biodegradables d'administration de medicaments - Google Patents
Compositions biodegradables d'administration de medicamentsInfo
- Publication number
- MA34832B1 MA34832B1 MA36118A MA36118A MA34832B1 MA 34832 B1 MA34832 B1 MA 34832B1 MA 36118 A MA36118 A MA 36118A MA 36118 A MA36118 A MA 36118A MA 34832 B1 MA34832 B1 MA 34832B1
- Authority
- MA
- Morocco
- Prior art keywords
- drug delivery
- delivery compositions
- biodegradable drug
- polyester
- polyethylene glycol
- Prior art date
Links
- 238000012377 drug delivery Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 2
- 229920000728 polyester Polymers 0.000 abstract 2
- 229920001223 polyethylene glycol Polymers 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229920000359 diblock copolymer Polymers 0.000 abstract 1
- 229920000428 triblock copolymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
- A01N25/10—Macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/66—Polyesters containing oxygen in the form of ether groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
- C08L67/04—Polyesters derived from hydroxycarboxylic acids, e.g. lactones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Polymers & Plastics (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Endocrinology (AREA)
- Dentistry (AREA)
- Immunology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
Abstract
L'invention concerne des compositions biodégradables d'administration de médicaments comprenant un copolymère tribloc contenant un polyester et un polyéthylène glycol et un copolymère dibloc contenant un polyester et un polyéthylène glycol coiffé aux extrémités, ainsi qu'un principe pharmaceutiquement actif.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201061428007P | 2010-12-29 | 2010-12-29 | |
| PCT/IB2011/003323 WO2012090070A2 (fr) | 2010-12-29 | 2011-12-29 | Compositions biodégradables d'administration de médicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA34832B1 true MA34832B1 (fr) | 2014-01-02 |
Family
ID=45809329
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA36118A MA34832B1 (fr) | 2010-12-29 | 2011-12-29 | Compositions biodegradables d'administration de medicaments |
Country Status (36)
| Country | Link |
|---|---|
| US (9) | US9023897B2 (fr) |
| EP (3) | EP2658525B1 (fr) |
| JP (2) | JP6134269B2 (fr) |
| KR (1) | KR101741055B1 (fr) |
| CN (1) | CN103491946B (fr) |
| AU (1) | AU2011350898B2 (fr) |
| BR (1) | BR112013016662B1 (fr) |
| CA (1) | CA2822854C (fr) |
| CL (1) | CL2013001942A1 (fr) |
| CO (1) | CO6751290A2 (fr) |
| CU (1) | CU24203B1 (fr) |
| CY (1) | CY1119829T1 (fr) |
| DK (1) | DK2658525T3 (fr) |
| EA (1) | EA027046B1 (fr) |
| ES (3) | ES2647614T3 (fr) |
| FI (1) | FI3586825T3 (fr) |
| HR (1) | HRP20171810T1 (fr) |
| HU (1) | HUE037349T2 (fr) |
| IL (1) | IL227235A (fr) |
| LT (1) | LT2658525T (fr) |
| MA (1) | MA34832B1 (fr) |
| ME (1) | ME02915B (fr) |
| MX (1) | MX347090B (fr) |
| MY (1) | MY165655A (fr) |
| NO (1) | NO2658525T3 (fr) |
| NZ (1) | NZ612326A (fr) |
| PL (3) | PL2658525T3 (fr) |
| PT (1) | PT2658525T (fr) |
| RS (1) | RS56550B1 (fr) |
| SG (2) | SG10201508568VA (fr) |
| SI (1) | SI2658525T1 (fr) |
| SM (1) | SMT201700550T1 (fr) |
| TN (1) | TN2013000267A1 (fr) |
| UA (1) | UA112069C2 (fr) |
| WO (1) | WO2012090070A2 (fr) |
| ZA (1) | ZA201304687B (fr) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102189442B1 (ko) * | 2012-06-27 | 2020-12-11 | 메딘셀 에스.에이. | 소수성 조성물용 생분해성 약물 전달 |
| EP3907237A1 (fr) | 2012-12-20 | 2021-11-10 | Amgen Inc. | Agonistes du récepteur apj et leurs utilisations |
| EP2896402A1 (fr) | 2014-01-20 | 2015-07-22 | Vect-Horus | Molécules de neurotensine activés et leurs utilisations |
| CA2938019A1 (fr) | 2014-01-27 | 2015-07-30 | Centre National De La Recherche Scientifique | Analogues retro-inverso de spadine a effets antidepresseurs accrus |
| FR3027522B1 (fr) | 2014-10-27 | 2016-12-09 | I Ceram | Composition poreuse chargee en principe actif |
| WO2016144182A1 (fr) * | 2015-03-12 | 2016-09-15 | Xpand Biotechnology B.V. | Matériaux composites biocompatibles anhydres |
| US20170079985A1 (en) | 2015-09-21 | 2017-03-23 | Teva Pharmaceuticals International Gmbh | Sustained release olanzapine formulations |
| AU2016355236C1 (en) * | 2015-11-16 | 2022-09-22 | Medincell | A method for morselizing and/or targeting pharmaceutically active principles to synovial tissue |
| US20190343761A1 (en) | 2016-11-16 | 2019-11-14 | Persica Pharmaceuticals Ltd. | Antibiotic formulations for lower back pain |
| EP3600258A1 (fr) | 2017-03-20 | 2020-02-05 | Teva Pharmaceuticals International GmbH | Formulations d'olanzapine à libération prolongée |
| LT3655038T (lt) * | 2017-07-17 | 2025-02-10 | Medincell S.A. | Farmacinė kompozicija |
| CA3077037C (fr) | 2017-10-04 | 2024-01-23 | Fashion Chemicals Gmbh & Co. Kg | Esters d'acide polylactique et compositions connexes |
| GB201900258D0 (en) * | 2019-01-08 | 2019-02-27 | Medincell | Pharmaceutical composition |
| SI4027973T1 (sl) * | 2019-09-13 | 2026-02-27 | Medincell S.A. | Formulacije za dostavo zdravil |
| CN110638963A (zh) * | 2019-11-01 | 2020-01-03 | 慧生医学科技(徐州)有限公司 | 一种可降解缓释药物组合物及制备方法 |
| GB202010340D0 (en) | 2020-07-06 | 2020-08-19 | Medincell | Pharmaceutical composition |
| CN116847827A (zh) | 2020-12-16 | 2023-10-03 | 美蒂森股份公司 | 用于预防性治疗SARS-CoV-2病毒(COVID-19)的方法和组合物 |
| EP4014963A1 (fr) * | 2020-12-16 | 2022-06-22 | Medincell | Composition pharmaceutique |
| US20240100012A1 (en) | 2021-01-18 | 2024-03-28 | Mark Hasleton | Pharmaceutical dosage form |
| US20240148641A1 (en) | 2021-03-17 | 2024-05-09 | Medincell S.A. | Long Acting Injectable Formulation Comprising Risperidone and Biodegradable Polymers |
| CN116997323A (zh) * | 2021-03-17 | 2023-11-03 | 美蒂森股份公司 | 包含利培酮和可生物降解的聚合物的长效可注射制剂 |
| US20240325294A1 (en) * | 2021-04-30 | 2024-10-03 | Medincell Sa | Etonogestrel formulation |
| EP4366726A1 (fr) | 2021-07-06 | 2024-05-15 | Mark Hasleton | Traitement du syndrome de sevrage aux inhibiteurs de recapture de la sérotonine |
| MX2024001681A (es) | 2021-08-05 | 2024-03-04 | Medincell S A | Composicion farmaceutica. |
| WO2024052920A1 (fr) * | 2022-09-08 | 2024-03-14 | Ramot At Tel-Aviv University Ltd. | Formulations polymères programmables sensibles aux stimuli |
| CA3266264A1 (fr) | 2023-01-10 | 2024-07-18 | Medincell Sa | Compositions d'olanzapine et méthodes d'utilisation |
| AU2024381207A1 (en) | 2023-11-17 | 2026-05-14 | Institut National de la Santé et de la Recherche Médicale | Antineoplastic combinations |
| WO2025224317A1 (fr) * | 2024-04-25 | 2025-10-30 | Medincell S.A. | Procédé de ciblage de principe pharmaceutiquement actif dans le remplacement total du genou |
| WO2026013080A1 (fr) | 2024-07-08 | 2026-01-15 | InnoCore Technologies Holding B.V. | Composition pharmaceutique à base de polymères biodégradables comprenant de la polyoxazoline |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0092918B1 (fr) | 1982-04-22 | 1988-10-19 | Imperial Chemical Industries Plc | Formulations à libération continue |
| US5071643A (en) | 1986-10-17 | 1991-12-10 | R. P. Scherer Corporation | Solvent system enhancing the solubility of pharmaceuticals for encapsulation |
| EP0343850B1 (fr) * | 1988-05-23 | 1994-07-20 | The Procter & Gamble Company | Structures absorbantes obtenues à partir de pâtes mélangées |
| US4938763B1 (en) | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
| US5632727A (en) | 1988-10-03 | 1997-05-27 | Atrix Laboratories, Inc. | Biodegradable film dressing and method for its formation |
| US5221534A (en) * | 1989-04-26 | 1993-06-22 | Pennzoil Products Company | Health and beauty aid compositions |
| US5077049A (en) | 1989-07-24 | 1991-12-31 | Vipont Pharmaceutical, Inc. | Biodegradable system for regenerating the periodontium |
| USRE37950E1 (en) | 1990-04-24 | 2002-12-31 | Atrix Laboratories | Biogradable in-situ forming implants and methods of producing the same |
| US5565215A (en) | 1993-07-23 | 1996-10-15 | Massachusettes Institute Of Technology | Biodegradable injectable particles for imaging |
| ATE288270T1 (de) * | 1993-11-19 | 2005-02-15 | Janssen Pharmaceutica Nv | Mikroverkapselte 1,2-benzazole |
| KR0148704B1 (ko) | 1994-01-10 | 1998-08-17 | 김상응 | 생체분해성 약물전달용 고분자 |
| EP1125577B1 (fr) | 1994-04-08 | 2006-02-15 | QLT USA, Inc. | Compositions liquides pour la délivrance de médicaments |
| AU4652596A (en) | 1995-01-09 | 1996-07-31 | Atrix Laboratories, Inc. | Liquid polymer delivery system |
| DE19545257A1 (de) | 1995-11-24 | 1997-06-19 | Schering Ag | Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln |
| FR2741628B1 (fr) | 1995-11-29 | 1998-02-06 | Centre Nat Rech Scient | Nouveaux hydrogels a base de copolymeres trisequences et leur application notamment a la liberation progressive de principes actifs |
| US5792477A (en) * | 1996-05-07 | 1998-08-11 | Alkermes Controlled Therapeutics, Inc. Ii | Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent |
| IL118235A0 (en) | 1996-05-13 | 1996-09-12 | Univ Ben Gurion | Composition and method for forming biodegradable implants in situ and uses of these implants |
| US5711958A (en) * | 1996-07-11 | 1998-01-27 | Life Medical Sciences, Inc. | Methods for reducing or eliminating post-surgical adhesion formation |
| US6541033B1 (en) | 1998-06-30 | 2003-04-01 | Amgen Inc. | Thermosensitive biodegradable hydrogels for sustained delivery of leptin |
| US6261583B1 (en) | 1998-07-28 | 2001-07-17 | Atrix Laboratories, Inc. | Moldable solid delivery system |
| US6143314A (en) | 1998-10-28 | 2000-11-07 | Atrix Laboratories, Inc. | Controlled release liquid delivery compositions with low initial drug burst |
| US6565874B1 (en) | 1998-10-28 | 2003-05-20 | Atrix Laboratories | Polymeric delivery formulations of leuprolide with improved efficacy |
| US7374779B2 (en) * | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
| KR100416242B1 (ko) | 1999-12-22 | 2004-01-31 | 주식회사 삼양사 | 약물전달체용 생분해성 블록 공중합체의 액체 조성물 및이의 제조방법 |
| KR100446101B1 (ko) | 2000-12-07 | 2004-08-30 | 주식회사 삼양사 | 수난용성 약물의 서방성 제형 조성물 |
| US6592899B2 (en) | 2001-10-03 | 2003-07-15 | Macromed Incorporated | PLA/PLGA oligomers combined with block copolymers for enhancing solubility of a drug in water |
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| US7160551B2 (en) | 2002-07-09 | 2007-01-09 | The Board Of Trustees Of The University Of Illinois | Injectable system for controlled drug delivery |
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| AR064286A1 (es) * | 2006-12-13 | 2009-03-25 | Quiceno Gomez Alexandra Lorena | Produccion de dispositivos oftalmicos basados en la polimerizacion por crecimiento escalonado fotoinducida |
| US20090004243A1 (en) | 2007-06-29 | 2009-01-01 | Pacetti Stephen D | Biodegradable triblock copolymers for implantable devices |
| WO2009060473A2 (fr) | 2007-11-06 | 2009-05-14 | Panacea Biotec Limited | Compositions injectables, procédés et utilisations correspondantes |
| JP2010215562A (ja) | 2009-03-17 | 2010-09-30 | Kansai Univ | 膨隆剤組成物および膨隆剤製造方法 |
-
2011
- 2011-12-29 MY MYPI2013002458A patent/MY165655A/en unknown
- 2011-12-29 ES ES11822867.5T patent/ES2647614T3/es active Active
- 2011-12-29 BR BR112013016662-2A patent/BR112013016662B1/pt active IP Right Grant
- 2011-12-29 FI FIEP19169971.9T patent/FI3586825T3/fi active
- 2011-12-29 SG SG10201508568VA patent/SG10201508568VA/en unknown
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2013
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2020
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2022
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