MA35809B1 - Procédé de production de dérivés d'imidazole - Google Patents

Procédé de production de dérivés d'imidazole

Info

Publication number
MA35809B1
MA35809B1 MA36668A MA36668A MA35809B1 MA 35809 B1 MA35809 B1 MA 35809B1 MA 36668 A MA36668 A MA 36668A MA 36668 A MA36668 A MA 36668A MA 35809 B1 MA35809 B1 MA 35809B1
Authority
MA
Morocco
Prior art keywords
imidazole derivatives
compound
reagent
producing imidazole
producing
Prior art date
Application number
MA36668A
Other languages
English (en)
Inventor
Yoichi Kawabata
Yasuhiro Sawai
Kazuaki Kanno
Naotaka Sawada
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46458578&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA35809(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of MA35809B1 publication Critical patent/MA35809B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La présente invention concerne un procédé de production avantageux d'un dérivé d'imidazole qui est approprié pour une production industrielle. Un composé (vi) est produit par la réaction d'un composé (i) avec un réactif de grignard ou un réactif du magnésium, et un réactif du lithium, puis par la réaction du composant résultant avec un composé (v).
MA36668A 2011-06-15 2014-01-10 Procédé de production de dérivés d'imidazole MA35809B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011133712 2011-06-15
PCT/JP2012/065795 WO2012173280A1 (fr) 2011-06-15 2012-06-14 Procédé de production de dérivés d'imidazole

Publications (1)

Publication Number Publication Date
MA35809B1 true MA35809B1 (fr) 2014-12-01

Family

ID=46458578

Family Applications (1)

Application Number Title Priority Date Filing Date
MA36668A MA35809B1 (fr) 2011-06-15 2014-01-10 Procédé de production de dérivés d'imidazole

Country Status (27)

Country Link
US (2) US9278938B2 (fr)
EP (1) EP2721010B1 (fr)
JP (1) JP6082353B2 (fr)
KR (1) KR20140028069A (fr)
CN (1) CN103608334B (fr)
AR (1) AR086926A1 (fr)
AU (1) AU2012270496A1 (fr)
BR (1) BR112013030888A2 (fr)
CA (1) CA2838971C (fr)
CL (1) CL2013003492A1 (fr)
CO (1) CO6852075A2 (fr)
CR (1) CR20130655A (fr)
DO (1) DOP2013000287A (fr)
EA (1) EA201490019A1 (fr)
EC (1) ECSP14013128A (fr)
ES (1) ES2554454T3 (fr)
IL (1) IL229566A0 (fr)
MA (1) MA35809B1 (fr)
MX (1) MX2013014009A (fr)
PE (1) PE20141326A1 (fr)
PH (1) PH12013502567A1 (fr)
SG (1) SG195036A1 (fr)
TN (1) TN2013000481A1 (fr)
TW (1) TW201307295A (fr)
UY (1) UY34130A (fr)
WO (1) WO2012173280A1 (fr)
ZA (1) ZA201308884B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10864460B2 (en) * 2014-09-30 2020-12-15 Unm Rainforest Innovations Graphene-based inorganic-organic hybrid materials and separation of racemic mixtures
US20200033307A1 (en) * 2018-07-25 2020-01-30 Honeywell International Inc. Method of determining an amount of water in a sample using a derivative of imidazole and a hydrogen halide donor
KR102253950B1 (ko) * 2019-07-24 2021-05-20 (주)에니켐텍 신규한 메데토미딘 제조방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5832880A (ja) * 1981-08-24 1983-02-25 Isukura Sangyo Kk ハリントニンの部分合成方法
WO2000078727A1 (fr) 1999-06-22 2000-12-28 Takeda Chemical Industries, Ltd. Methode de preparation de derives d'imidazole
PE20010781A1 (es) 1999-10-22 2001-08-08 Takeda Chemical Industries Ltd Compuestos 1-(1h-imidazol-4-il)-1-(naftil-2-sustituido)etanol, su produccion y utilizacion
DE10031604A1 (de) 2000-06-29 2002-01-17 Consortium Elektrochem Ind Verfahren zur Herstellung von beta-Hydroxy- und beta-Aminocarbonylverbindungen
JP3753971B2 (ja) * 2000-11-17 2006-03-08 武田薬品工業株式会社 新規イミダゾール誘導体、その製造法および用途
WO2003059839A1 (fr) 2002-01-04 2003-07-24 Koninklijke Philips Electronics N.V. Element fritte et lampe electrique
EP1471056B1 (fr) 2002-01-10 2012-07-11 Takeda Pharmaceutical Company Limited Procede relatif a l'elaboration de compose d'imidazole fondu, reactif de reformatsky sous forme stable, et procede d'elaboration correspondant
EP1394140A1 (fr) * 2002-08-14 2004-03-03 Consortium für elektrochemische Industrie GmbH Procede enantioselectif reformatsky de preparation d'alcohols, d'amines optiqument actif et leur derive
CN101795630B (zh) 2007-06-29 2013-03-06 阿瑟罗迈德公司 旋切术装置、系统和方法

Also Published As

Publication number Publication date
ES2554454T3 (es) 2015-12-21
TN2013000481A1 (en) 2015-03-30
CN103608334B (zh) 2015-12-23
US10005780B2 (en) 2018-06-26
DOP2013000287A (es) 2014-02-16
CA2838971A1 (fr) 2012-12-20
EP2721010A1 (fr) 2014-04-23
US9278938B2 (en) 2016-03-08
US20140100373A1 (en) 2014-04-10
UY34130A (es) 2013-01-31
AR086926A1 (es) 2014-01-29
CR20130655A (es) 2014-03-03
CL2013003492A1 (es) 2014-07-18
EA201490019A1 (ru) 2014-04-30
KR20140028069A (ko) 2014-03-07
PE20141326A1 (es) 2014-10-16
EP2721010B1 (fr) 2015-09-09
IL229566A0 (en) 2014-01-30
TW201307295A (zh) 2013-02-16
US20160244454A1 (en) 2016-08-25
BR112013030888A2 (pt) 2017-03-21
CA2838971C (fr) 2019-07-30
ZA201308884B (en) 2015-02-25
MX2013014009A (es) 2014-03-12
JP2014520066A (ja) 2014-08-21
JP6082353B2 (ja) 2017-02-15
CO6852075A2 (es) 2014-01-30
AU2012270496A1 (en) 2013-12-19
ECSP14013128A (es) 2014-02-28
WO2012173280A1 (fr) 2012-12-20
PH12013502567A1 (en) 2014-01-27
CN103608334A (zh) 2014-02-26
SG195036A1 (en) 2013-12-30

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