MA38253A1 - Compositions comprenant de la vortioxétine et du donépézil - Google Patents
Compositions comprenant de la vortioxétine et du donépézilInfo
- Publication number
- MA38253A1 MA38253A1 MA38253A MA38253A MA38253A1 MA 38253 A1 MA38253 A1 MA 38253A1 MA 38253 A MA38253 A MA 38253A MA 38253 A MA38253 A MA 38253A MA 38253 A1 MA38253 A1 MA 38253A1
- Authority
- MA
- Morocco
- Prior art keywords
- compositions
- vortioxetine
- donepezil
- treatment
- relates
- Prior art date
Links
- ADEBPBSSDYVVLD-UHFFFAOYSA-N donepezil Chemical compound O=C1C=2C=C(OC)C(OC)=CC=2CC1CC(CC1)CCN1CC1=CC=CC=C1 ADEBPBSSDYVVLD-UHFFFAOYSA-N 0.000 title abstract 4
- 229960003530 donepezil Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- YQNWZWMKLDQSAC-UHFFFAOYSA-N vortioxetine Chemical compound CC1=CC(C)=CC=C1SC1=CC=CC=C1N1CCNCC1 YQNWZWMKLDQSAC-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002263 vortioxetine Drugs 0.000 title abstract 2
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
L'invention concerne des compositions pharmaceutiques comprenant de la vortioxétine et du donépézil, et l'utilisation de ces compositions pour le traitement de dysfonctionnements cognitifs.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261736799P | 2012-12-13 | 2012-12-13 | |
| PCT/EP2013/076337 WO2014090929A1 (fr) | 2012-12-13 | 2013-12-12 | Compositions comprenant de la vortioxétine et du donépézil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA38253A1 true MA38253A1 (fr) | 2017-02-28 |
| MA38253B1 MA38253B1 (fr) | 2017-10-31 |
Family
ID=49943326
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA38253A MA38253B1 (fr) | 2012-12-13 | 2013-12-12 | Compositions comprenant de la vortioxétine et du donépézil |
Country Status (44)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105218482B (zh) * | 2014-06-24 | 2018-04-06 | 杭州和泽医药科技有限公司 | 沃替西汀氢溴酸盐β晶型的制备方法 |
| CN104610195B (zh) * | 2015-01-30 | 2017-06-27 | 上虞京新药业有限公司 | 沃替西汀的天冬氨酸盐或其水合物及其制备方法和用途 |
| CN105315184B (zh) * | 2015-06-26 | 2017-03-29 | 上海医药工业研究院 | 一种沃替西汀的制备方法及其中间体 |
| EP3324952B1 (fr) * | 2015-07-17 | 2020-12-16 | Institut Pasteur | Agent récepteur-stimulant 5-hydroxytryptamine1b destiné à être utilisé comme promoteur de l'autorenouvellement de cellules et/ou la différenciation par satellite |
| CN105534933A (zh) * | 2016-01-19 | 2016-05-04 | 美吉斯制药(厦门)有限公司 | 一种沃替西汀口腔崩解片及其制备方法 |
| JP2019524682A (ja) | 2016-07-01 | 2019-09-05 | ハー・ルンドベック・アクチエゼルスカベット | 抗うつ作用の速い発現のためのボルチオキセチン投与計画 |
| US20190216803A1 (en) | 2017-03-30 | 2019-07-18 | Rundle Research, LLC | Methods of treating depression with vortioxetine |
| WO2018182639A1 (fr) | 2017-03-30 | 2018-10-04 | Rundle Research, LLC | Méthodes de traitement de la dépression |
| US10398691B2 (en) | 2017-03-30 | 2019-09-03 | Rundle Research, LLC | Methods of treating depression |
| EP3870292A4 (fr) | 2018-10-26 | 2022-11-09 | The Research Foundation for The State University of New York | Combinaison d'un inhibiteur de réabsorption spécifique de la sérotonine et d'un agoniste partiel du récepteur de la sérotonine 1a pour réduire la dyskinésie induite par l-dopa |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0268871A1 (fr) | 1986-10-31 | 1988-06-01 | Sumitomo Pharmaceuticals Company, Limited | Dérivés de quinoléine |
| IT1225462B (it) | 1987-04-03 | 1990-11-14 | Mediolanum Farmaceutici Srl | Sali organici di derivati della fisostigmina |
| KR100195399B1 (ko) | 1987-05-04 | 1999-06-15 | 보니데이비스 | 알쯔하이머 병 치료용 의약 |
| EP0403713A1 (fr) | 1989-06-22 | 1990-12-27 | Merrell Dow Pharmaceuticals Inc. | Inhibiteurs d'acétylcholinestérase |
| US4914102A (en) | 1989-09-28 | 1990-04-03 | Hoechst Roussel Pharmaceuticals, Inc. | N-aminocarbamates related to physostigmine, pharmacentical compositions and use |
| TW200462B (fr) | 1990-09-27 | 1993-02-21 | Hoechst Roussel Pharma | |
| US5246947A (en) | 1991-09-23 | 1993-09-21 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted pyridinylamino-1,2-benzisothiazoles and their use for treating depression |
| US5231093A (en) | 1991-10-01 | 1993-07-27 | Hoechst-Roussel Pharmaceuticals Incorporated | Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs |
| ES2042384B1 (es) | 1991-12-26 | 1994-06-01 | Boehringer Ingelheim Espana | Procedimiento para obtener derivados bis-piridinicos. |
| SE9302080D0 (sv) | 1993-06-16 | 1993-06-16 | Ab Astra | New compounds |
| WO1997038993A1 (fr) | 1996-04-12 | 1997-10-23 | Hoechst Marion Roussel, Inc. | Derives d'isatine utilises comme inhibiteurs d'acetylcholinesterase et comme analgesiques |
| UA81749C2 (uk) | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| JP4405811B2 (ja) | 2002-03-29 | 2010-01-27 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | (1−インダノン)−(1,2,3,6−テトラヒドロピリジン)誘導体 |
| WO2003101458A1 (fr) * | 2002-05-31 | 2003-12-11 | H. Lundbeck A/S | Combinaison d'un antagoniste de n-methyl d-aspartate et d'inhibiteurs de l'esterase d'acetylcholine pour le traitement de la maladie d'alzheimer |
| NZ541282A (en) * | 2002-12-24 | 2009-02-28 | Bellus Health International Ltd | Therapeutic formulations for the treatment of beta-amyloid related diseases |
| IN266817B (fr) * | 2006-05-08 | 2015-06-03 | Teikoku Seiyaku Kk | |
| JP2009539850A (ja) * | 2006-06-09 | 2009-11-19 | ワイス | 認知機能を増強する方法 |
| KR20090028712A (ko) * | 2006-06-16 | 2009-03-19 | 하. 룬트벡 아크티에 셀스카브 | 인지기능 장애의 치료를 위한, 세로토닌 재흡수, 5-ht3 및 5-ht1a 활성이 조합된 화합물로서의 1-[2-(2,4-디메틸페닐술파닐)-페닐]피페라진 |
| WO2009005519A1 (fr) * | 2007-06-29 | 2009-01-08 | Accera, Inc. | Combinaisons de triglycérides à chaîne moyenne et d'agents thérapeutiques pour le traitement et la prévention de la maladie d'alzheimer et d'autres maladies résultant d'un métabolisme neuronal réduit |
| TW200932233A (en) | 2007-11-13 | 2009-08-01 | Lundbeck & Co As H | Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity |
| TW201033181A (en) | 2009-02-17 | 2010-09-16 | Lundbeck & Co As H | Purification of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine |
-
2013
- 2013-12-12 CN CN201380065034.2A patent/CN104853755B/zh active Active
- 2013-12-12 MY MYPI2015001479A patent/MY171802A/en unknown
- 2013-12-12 LT LTEP13818702.6T patent/LT2931276T/lt unknown
- 2013-12-12 JP JP2015547020A patent/JP6257641B2/ja active Active
- 2013-12-12 US US14/649,087 patent/US9211288B2/en active Active
- 2013-12-12 CA CA2893468A patent/CA2893468C/fr active Active
- 2013-12-12 PL PL13818702T patent/PL2931276T3/pl unknown
- 2013-12-12 PT PT138187026T patent/PT2931276T/pt unknown
- 2013-12-12 EP EP13818702.6A patent/EP2931276B1/fr active Active
- 2013-12-12 SG SG11201504483YA patent/SG11201504483YA/en unknown
- 2013-12-12 AR ARP130104651A patent/AR093939A1/es not_active Application Discontinuation
- 2013-12-12 EA EA201590932A patent/EA028300B1/ru not_active IP Right Cessation
- 2013-12-12 HR HRP20180333TT patent/HRP20180333T1/hr unknown
- 2013-12-12 AU AU2013357308A patent/AU2013357308B2/en not_active Ceased
- 2013-12-12 BR BR112015013675-3A patent/BR112015013675B1/pt not_active IP Right Cessation
- 2013-12-12 NZ NZ708595A patent/NZ708595A/en not_active IP Right Cessation
- 2013-12-12 GE GEAP201313850A patent/GEP201706739B/en unknown
- 2013-12-12 KR KR1020157015715A patent/KR102171152B1/ko not_active Expired - Fee Related
- 2013-12-12 MX MX2015007269A patent/MX362886B/es active IP Right Grant
- 2013-12-12 PE PE2015000879A patent/PE20151026A1/es active IP Right Grant
- 2013-12-12 AP AP2015008498A patent/AP2015008498A0/xx unknown
- 2013-12-12 SM SM20180135T patent/SMT201800135T1/it unknown
- 2013-12-12 UA UAA201506381A patent/UA114016C2/uk unknown
- 2013-12-12 RS RS20180285A patent/RS56949B1/sr unknown
- 2013-12-12 SI SI201330970T patent/SI2931276T1/en unknown
- 2013-12-12 DK DK13818702.6T patent/DK2931276T3/en active
- 2013-12-12 ME MEP-2018-66A patent/ME03029B/fr unknown
- 2013-12-12 RU RU2015122256A patent/RU2635528C2/ru active
- 2013-12-12 MA MA38253A patent/MA38253B1/fr unknown
- 2013-12-12 HU HUE13818702A patent/HUE036280T2/hu unknown
- 2013-12-12 ES ES13818702.6T patent/ES2663680T3/es active Active
- 2013-12-12 WO PCT/EP2013/076337 patent/WO2014090929A1/fr not_active Ceased
-
2014
- 2014-03-05 NO NO14709546A patent/NO2970700T3/no unknown
-
2015
- 2015-05-27 TN TNP2015000235A patent/TN2015000235A1/fr unknown
- 2015-06-03 IL IL239192A patent/IL239192B/en active IP Right Grant
- 2015-06-03 DO DO2015000133A patent/DOP2015000133A/es unknown
- 2015-06-08 PH PH12015501302A patent/PH12015501302A1/en unknown
- 2015-06-08 GT GT201500143A patent/GT201500143A/es unknown
- 2015-06-09 CR CR20150303A patent/CR20150303A/es unknown
- 2015-06-09 EC ECIEPI201523182A patent/ECSP15023182A/es unknown
- 2015-06-09 NI NI201500078A patent/NI201500078A/es unknown
- 2015-06-10 CL CL2015001615A patent/CL2015001615A1/es unknown
- 2015-06-12 ZA ZA2015/04274A patent/ZA201504274B/en unknown
-
2018
- 2018-03-27 CY CY20181100347T patent/CY1120098T1/el unknown
-
2022
- 2022-05-19 AR ARP220101337A patent/AR125920A2/es not_active Application Discontinuation
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