MA38472A1 - Composé peptidique - Google Patents
Composé peptidiqueInfo
- Publication number
- MA38472A1 MA38472A1 MA38472A MA38472A MA38472A1 MA 38472 A1 MA38472 A1 MA 38472A1 MA 38472 A MA38472 A MA 38472A MA 38472 A MA38472 A MA 38472A MA 38472 A1 MA38472 A1 MA 38472A1
- Authority
- MA
- Morocco
- Prior art keywords
- peptide compound
- relates
- medicament
- receptors
- peptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
Abstract
La présente invention concerne un nouveau composé peptidique ayant pour effet d'activer les récepteurs au glp-1 et les récepteurs au gip, ainsi que l'utilisation dudit composé peptidique en tant que médicament. L'invention concerne, plus précisément, un peptide contenant une séquence partielle représentée par la formule (i), ou un sel de celui-ci et un médicament en contenant. P
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013111893 | 2013-05-28 | ||
| PCT/JP2014/002772 WO2014192284A1 (fr) | 2013-05-28 | 2014-05-27 | Composé peptidique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA38472A1 true MA38472A1 (fr) | 2018-01-31 |
| MA38472B1 MA38472B1 (fr) | 2018-09-28 |
Family
ID=50942304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA38472A MA38472B1 (fr) | 2013-05-28 | 2014-05-27 | Composé peptidique |
Country Status (35)
| Country | Link |
|---|---|
| US (2) | US9200051B2 (fr) |
| EP (1) | EP3004155B1 (fr) |
| JP (2) | JP6429799B2 (fr) |
| KR (1) | KR102229051B1 (fr) |
| CN (1) | CN105209485B (fr) |
| AP (1) | AP2015008781A0 (fr) |
| AR (1) | AR096440A1 (fr) |
| AU (1) | AU2014272500B2 (fr) |
| CA (1) | CA2908581C (fr) |
| CL (1) | CL2015003031A1 (fr) |
| CY (1) | CY1124790T1 (fr) |
| DK (1) | DK3004155T3 (fr) |
| DO (1) | DOP2015000261A (fr) |
| EA (2) | EA035813B1 (fr) |
| EC (1) | ECSP15044389A (fr) |
| ES (1) | ES2900744T3 (fr) |
| GE (1) | GEP201706762B (fr) |
| HR (1) | HRP20212014T1 (fr) |
| HU (1) | HUE057361T2 (fr) |
| IL (1) | IL242005B (fr) |
| LT (1) | LT3004155T (fr) |
| MA (1) | MA38472B1 (fr) |
| MX (2) | MX388826B (fr) |
| MY (1) | MY172744A (fr) |
| PE (1) | PE20151770A1 (fr) |
| PH (1) | PH12015502391B1 (fr) |
| PL (1) | PL3004155T3 (fr) |
| PT (1) | PT3004155T (fr) |
| SG (1) | SG11201507934PA (fr) |
| SI (1) | SI3004155T1 (fr) |
| TN (1) | TN2015000451A1 (fr) |
| TW (1) | TWI638831B (fr) |
| UA (1) | UA118558C2 (fr) |
| UY (1) | UY35589A (fr) |
| WO (1) | WO2014192284A1 (fr) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3004155T1 (sl) | 2013-05-28 | 2022-02-28 | Takeda Pharmaceutical Company Limited | Peptidna spojina |
| TWI582109B (zh) * | 2015-01-09 | 2017-05-11 | 美國禮來大藥廠 | Gip及glp-1共促效劑化合物 |
| CN104846061A (zh) * | 2015-05-07 | 2015-08-19 | 中国药科大学 | 一种glp-1受体激动剂的受体亲和力测定方法 |
| CN105388239B (zh) * | 2015-12-18 | 2018-01-05 | 兆科药业(合肥)有限公司 | 一种多肽固相合成的监测方法 |
| JP6995042B2 (ja) * | 2016-05-24 | 2022-02-04 | 武田薬品工業株式会社 | ペプチド化合物 |
| US11285180B2 (en) | 2016-12-06 | 2022-03-29 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods of enhancing the potency of incretin-based drugs in subjects in need thereof |
| JOP20190211A1 (ar) * | 2017-03-31 | 2019-09-15 | Takeda Pharmaceuticals Co | ببتيد منشط لمستقبل gip |
| WO2019140030A1 (fr) | 2018-01-12 | 2019-07-18 | Eli Lilly And Company | Polythérapie |
| WO2019147650A1 (fr) * | 2018-01-23 | 2019-08-01 | Gila Therapeutics, Inc. | Formulations pharmaceutiques de peptide yy, compositions et procédés |
| US11633459B2 (en) | 2018-05-04 | 2023-04-25 | Novo Nordisk A/S | GIP derivatives and uses thereof |
| CN119499352A (zh) * | 2018-07-23 | 2025-02-25 | 伊莱利利公司 | 使用gip/glp1共激动剂用于糖尿病的方法 |
| CN110818771B (zh) * | 2018-08-14 | 2023-01-17 | 陈铭 | 使用氨基酸离子液体的羰基硫介导多肽合成 |
| US12122815B2 (en) | 2018-09-24 | 2024-10-22 | Takeda Pharmaceutical Company Limited | GIP receptor agonist peptide compounds and uses thereof |
| EP3856339A1 (fr) * | 2018-09-24 | 2021-08-04 | Takeda Pharmaceutical Company Limited | Composés peptidiques agonistes du récepteur gip et leurs utilisations |
| KR102812908B1 (ko) * | 2019-08-19 | 2025-05-28 | 일라이 릴리 앤드 캄파니 | 인크레틴 유사체의 제조 방법 |
| KR20210040818A (ko) | 2019-10-04 | 2021-04-14 | 한미약품 주식회사 | 글루카곤, 및 glp-1 수용체 및 gip 수용체 이중 작용제를 포함하는 조성물 및 이의 치료학적 용도 |
| CN110684082B (zh) | 2019-10-08 | 2021-12-10 | 江苏诺泰澳赛诺生物制药股份有限公司 | Gip和glp-1双激动多肽化合物及药学上可接受的盐与用途 |
| CN115335395A (zh) * | 2020-03-25 | 2022-11-11 | 武田药品工业株式会社 | Gip受体激动剂肽化合物的qd给药及其用途 |
| WO2021198229A1 (fr) * | 2020-03-31 | 2021-10-07 | Antaros Medical Ab | Agonistes sélectifs du récepteur de gip comprenant une fraction chélatante à des fins d'imagerie et de thérapie |
| US20230346961A1 (en) | 2020-07-22 | 2023-11-02 | Novo Nordisk A/S | Glp-1 and gip receptor co-agonists |
| EP4185607A1 (fr) | 2020-07-22 | 2023-05-31 | Novo Nordisk A/S | Co-agonistes au niveau des récepteurs de glp-1 et de gip appropriés pour une administration par voie orale |
| US12029718B2 (en) | 2021-11-09 | 2024-07-09 | Cct Sciences, Llc | Process for production of essentially pure delta-9-tetrahydrocannabinol |
| EP4345105A4 (fr) | 2021-06-01 | 2025-04-23 | Nanjing Zhihe Medicine Technology Co., Ltd | Dérivé polypeptidique ayant un effet d'activation à double cible de glp-1r et de gipr, procédé de préparation associé et son utilisation |
| TW202330584A (zh) | 2022-01-20 | 2023-08-01 | 丹麥商諾佛 儂迪克股份有限公司 | 前藥及其用途 |
| EP4556487A1 (fr) | 2022-07-13 | 2025-05-21 | Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. | Agoniste double de glp-1/gip, son procédé de préparation et son utilisation |
| WO2024020388A1 (fr) * | 2022-07-20 | 2024-01-25 | Viking Therapeutics, Inc. | Formulations pharmaceutiques et méthodes pour le traitement de troubles métaboliques et hépatiques |
| CN119894921A (zh) | 2022-09-15 | 2025-04-25 | 伊莱利利公司 | Gip和glp-1双重激动剂化合物 |
| JP2026502943A (ja) | 2022-12-30 | 2026-01-27 | アルギファルマ エーエス | 経口投与されるポリペプチド治療剤の全身バイオアベイラビリティを高める組成物および方法 |
| WO2024165571A2 (fr) | 2023-02-06 | 2024-08-15 | E-Therapeutics Plc | Inhibiteurs d'expression et/ou de fonction |
| EP4714434A1 (fr) | 2023-05-19 | 2026-03-25 | Aulbio Co., Ltd. | Microsphère comprenant du tirzépatide, son procédé de préparation, et composition pharmaceutique la comprenant |
| KR20260022948A (ko) | 2023-06-09 | 2026-02-20 | 썬 파마슈티컬 인더스트리스 리미티드 | Glp-1/gip 이중 수용체 작용제, glp-1/gcg 이중 수용체 작용제, 및 glp-1/gip/gcg 삼중 수용체 작용제 |
| TW202517291A (zh) | 2023-06-30 | 2025-05-01 | 丹麥商西蘭製藥公司 | 組合療法 |
| TW202529796A (zh) * | 2023-11-22 | 2025-08-01 | 大陸商杭州中美華東製藥有限公司 | Glp-1r/gipr雙標靶激動劑在製備動物藥的用途 |
| TW202540155A (zh) | 2023-11-30 | 2025-10-16 | 丹麥商諾佛 儂迪克股份有限公司 | Glp-1、gip及澱粉素受體之三重促效劑 |
| WO2025125576A2 (fr) | 2023-12-15 | 2025-06-19 | E-Therapeutics Plc | Inhibiteurs d'expression et/ou de fonction |
| EP4686757A1 (fr) | 2024-07-31 | 2026-02-04 | e-therapeutics PLC | Inhibiteurs d expression et/ou de fonction |
| WO2025133348A1 (fr) | 2023-12-22 | 2025-06-26 | E-Therapeutics Plc | Inhibiteurs d'expression et/ou de fonction |
| TW202542174A (zh) * | 2023-12-29 | 2025-11-01 | 大陸商杭州中美華東製藥有限公司 | Glp-1/gip雙激動劑的固相合成方法 |
| WO2025149039A1 (fr) * | 2024-01-12 | 2025-07-17 | 杭州中美华东制药有限公司 | Composition pharmaceutique d'agoniste double de glp-1/gip à action prolongée |
| TW202535912A (zh) * | 2024-01-12 | 2025-09-16 | 大陸商杭州中美華東製藥有限公司 | 長效glp-1/gip雙激動劑的鼻腔遞送藥物組合物 |
| WO2025196502A1 (fr) | 2024-03-20 | 2025-09-25 | North Carolina Agricultural & Technical State University | Inhibiteurs de choline kinase utilisés en tant que traitement thérapeutique contre l'obésité |
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|---|---|---|---|---|
| UA65549C2 (uk) | 1996-11-05 | 2004-04-15 | Елі Ліллі Енд Компані | Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція |
| DE69732572T2 (de) | 1996-11-12 | 2005-12-29 | Novo Nordisk A/S | Verwendung von glp-1 peptiden |
| WO1999047161A1 (fr) | 1998-03-19 | 1999-09-23 | Bionebraska, Inc. | Regulation de l'appetit chez les humains par un compose se liant a un recepteur de peptide de type glucagon |
| ATE251465T1 (de) | 1998-07-31 | 2003-10-15 | Novo Nordisk As | In-vitro stimulation von beta zellen vermehrung |
| EP1992641A3 (fr) | 1998-12-07 | 2009-07-29 | Ipsen Pharma | Analogues GLP-1 |
| AU5675701A (en) | 2000-05-16 | 2001-11-26 | Sanwa Kagaku Kenkyusho Co | Agents for preventing or ameliorating insulin resistance and/or obesity |
| WO2004005342A1 (fr) | 2002-07-04 | 2004-01-15 | Zealand Pharma A/S | Glp-1 et methodes de traitement du diabete |
| JP2007536214A (ja) | 2003-12-16 | 2007-12-13 | ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス | Glp−1類似体 |
| WO2006049681A2 (fr) | 2004-08-30 | 2006-05-11 | Bayer Pharmaceuticals Corporation | Agonistes recepteur y2 neuropeptidiques selectifs |
| KR20070115947A (ko) | 2005-02-11 | 2007-12-06 | 아밀린 파마슈티칼스, 인크. | 선택가능한 특성들을 가지는 gip 유사체 및 하이브리드폴리펩타이드 |
| WO2006136374A2 (fr) | 2005-06-20 | 2006-12-28 | Develogen Aktiengesellschaft | Utilisation du gip et/ou de la vitamine d3 et d'analogues correspondants pour ameliorer la differenciation de cellules souches ou progenitrices en cellules productrices d'insuline |
| JP2009542813A (ja) | 2006-07-11 | 2009-12-03 | ハルクネスス プハルマセウティカルス,インコーポレイテッド | 飽食因子を使用して肥満を治療する方法 |
| WO2008021560A2 (fr) | 2006-08-17 | 2008-02-21 | Amylin Pharmaceuticals, Inc. | Analogue du gip et polypeptides hybrides possédant des propriétés sélectives |
| TWI430806B (zh) | 2006-09-13 | 2014-03-21 | Smithkline Beecham Corp | 用於投與長效降血糖藥劑之方法 |
| EP1972349A1 (fr) | 2007-03-21 | 2008-09-24 | Biocompatibles UK Limited | Peptides à fusion GLP-1 associée à un/plusieurs polymères, leur production et utilisation |
| US8710002B2 (en) | 2007-11-23 | 2014-04-29 | Michael Rothkopf | Methods of enhancing diabetes resolution |
| CN102105159B (zh) | 2008-06-17 | 2015-07-08 | 印第安纳大学研究及科技有限公司 | 基于gip的混合激动剂用于治疗代谢紊乱和肥胖症 |
| AU2009280021B2 (en) | 2008-08-07 | 2012-10-04 | Ipsen Pharma S.A.S. | Analogues of glucose-dependent insulinotropic polypeptide (GIP) modified at N-terminal |
| PT2373681T (pt) | 2008-12-10 | 2017-04-11 | Glaxosmithkline Llc | Composições farmacêuticas de albiglutida |
| EP2443146B1 (fr) | 2009-06-16 | 2016-10-05 | Indiana University Research And Technology Corporation | Composés de glucagon actifs sur le récepteur gip |
| US9260500B2 (en) | 2009-07-02 | 2016-02-16 | Takeda Pharmaceutical Company Limited | Peptide and use thereof |
| KR20120123443A (ko) | 2010-01-27 | 2012-11-08 | 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 | 대사 장애 및 비만 치료용 글루카곤 길항제-gip 항진제 콘쥬게이트 |
| AR080592A1 (es) | 2010-03-26 | 2012-04-18 | Lilly Co Eli | Peptido con actividad para el gip-r y glp-1-r, formulacion famaceutica que lo comprende, su uso para preparar un medicamento util para el tratamiento de diabetes mellitus y para inducir la perdida de peso |
| WO2012088379A2 (fr) | 2010-12-22 | 2012-06-28 | Marcadia Biotech, Inc. | Méthodes de traitement des affections métaboliques et de l'obésité faisant appel à des peptides associés au glucagon, actifs sur les récepteurs gip et glp-1 |
| DK2694095T3 (en) | 2011-04-05 | 2018-05-28 | Longevity Biotech Inc | COMPOSITIONS COMPREHENSIVE GLUCAGON ANALOGS AND METHODS FOR PREPARING AND USING THE SAME |
| JP6121992B2 (ja) | 2011-06-10 | 2017-04-26 | ノヴォ ノルディスク アー/エス | ポリペプチド |
| US9453062B2 (en) * | 2011-06-10 | 2016-09-27 | Beijing Hanmi Pharmaceutical Co., Ltd. | Glucose dependent insulinotropic polypeptide analogs, pharmaceutical compositions and use thereof |
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| CN105829339B (zh) | 2013-11-06 | 2021-03-12 | 西兰制药公司 | 胰高血糖素-glp-1-gip三重激动剂化合物 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物 |
| JP2018012644A (ja) | 2014-11-26 | 2018-01-25 | 武田薬品工業株式会社 | ペプチド化合物 |
-
2014
- 2014-05-27 SI SI201431933T patent/SI3004155T1/sl unknown
- 2014-05-27 EA EA201591891A patent/EA035813B1/ru unknown
- 2014-05-27 UA UAA201510946A patent/UA118558C2/uk unknown
- 2014-05-27 CN CN201480026613.0A patent/CN105209485B/zh active Active
- 2014-05-27 AR ARP140102090A patent/AR096440A1/es active IP Right Grant
- 2014-05-27 MX MX2019010531A patent/MX388826B/es unknown
- 2014-05-27 EA EA202090593A patent/EA202090593A3/ru unknown
- 2014-05-27 PT PT147299762T patent/PT3004155T/pt unknown
- 2014-05-27 ES ES14729976T patent/ES2900744T3/es active Active
- 2014-05-27 US US14/287,514 patent/US9200051B2/en active Active
- 2014-05-27 WO PCT/JP2014/002772 patent/WO2014192284A1/fr not_active Ceased
- 2014-05-27 EP EP14729976.2A patent/EP3004155B1/fr active Active
- 2014-05-27 MX MX2015015464A patent/MX373436B/es active IP Right Grant
- 2014-05-27 HR HRP20212014TT patent/HRP20212014T1/hr unknown
- 2014-05-27 GE GEAP201413984A patent/GEP201706762B/en unknown
- 2014-05-27 LT LTEPPCT/JP2014/002772T patent/LT3004155T/lt unknown
- 2014-05-27 AU AU2014272500A patent/AU2014272500B2/en active Active
- 2014-05-27 JP JP2015555470A patent/JP6429799B2/ja active Active
- 2014-05-27 TW TW103118374A patent/TWI638831B/zh active
- 2014-05-27 PL PL14729976T patent/PL3004155T3/pl unknown
- 2014-05-27 PE PE2015002124A patent/PE20151770A1/es unknown
- 2014-05-27 SG SG11201507934PA patent/SG11201507934PA/en unknown
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- 2014-05-27 UY UY0001035589A patent/UY35589A/es not_active Application Discontinuation
- 2014-05-27 HU HUE14729976A patent/HUE057361T2/hu unknown
- 2014-05-27 US US14/780,579 patent/US10087229B2/en active Active
- 2014-05-27 KR KR1020157032121A patent/KR102229051B1/ko active Active
- 2014-05-27 CA CA2908581A patent/CA2908581C/fr active Active
- 2014-05-27 MY MYPI2015703438A patent/MY172744A/en unknown
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- 2014-05-27 DK DK14729976.2T patent/DK3004155T3/da active
- 2014-05-27 MA MA38472A patent/MA38472B1/fr unknown
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2015
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2018
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2021
- 2021-12-15 CY CY20211101100T patent/CY1124790T1/el unknown
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