MA39059A1 - Système d'administration de médicament. - Google Patents

Système d'administration de médicament.

Info

Publication number
MA39059A1
MA39059A1 MA39059A MA39059A MA39059A1 MA 39059 A1 MA39059 A1 MA 39059A1 MA 39059 A MA39059 A MA 39059A MA 39059 A MA39059 A MA 39059A MA 39059 A1 MA39059 A1 MA 39059A1
Authority
MA
Morocco
Prior art keywords
therapeutic agent
thermoplastic polymer
delivery system
drug delivery
core
Prior art date
Application number
MA39059A
Other languages
English (en)
Inventor
Willy J H Verhoeven
Graaff Wouter De
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of MA39059A1 publication Critical patent/MA39059A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne un système intravaginal d'administration de médicament comprenant (i) un noyau comprenant un premier polymère thermoplastique et un premier agent thérapeutique, le premier agent thérapeutique étant dissous dans le premier polymère thermoplastique et (ii) une pellicule entourant le noyau comprenant un deuxième polymère thermoplastique, le premier agent thérapeutique étant moins perméable dans le deuxième polymère thermoplastique que dans le premier polymère thermoplastique, et un deuxième agent thérapeutique sous forme solide, le deuxième agent thérapeutique étant chargé dans une partie de la pellicule.
MA39059A 2013-12-11 2014-12-08 Système d'administration de médicament. MA39059A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13196737 2013-12-11
PCT/EP2014/076823 WO2015086491A1 (fr) 2013-12-11 2014-12-08 Système d'administration de médicament.

Publications (1)

Publication Number Publication Date
MA39059A1 true MA39059A1 (fr) 2018-08-31

Family

ID=49759119

Family Applications (1)

Application Number Title Priority Date Filing Date
MA39059A MA39059A1 (fr) 2013-12-11 2014-12-08 Système d'administration de médicament.

Country Status (23)

Country Link
US (1) US10413504B2 (fr)
EP (1) EP3079660B1 (fr)
JP (1) JP6251396B2 (fr)
KR (1) KR101808977B1 (fr)
CN (1) CN105979930B (fr)
AP (1) AP2016009223A0 (fr)
AU (1) AU2014363724B2 (fr)
BR (1) BR112016013325B1 (fr)
CA (1) CA2931559C (fr)
CR (1) CR20160261A (fr)
DO (1) DOP2016000132A (fr)
EA (1) EA031802B1 (fr)
HK (1) HK1224208A1 (fr)
IL (1) IL245544A0 (fr)
MA (1) MA39059A1 (fr)
MD (1) MD20160079A2 (fr)
MX (1) MX2016007681A (fr)
PE (1) PE20160680A1 (fr)
PH (1) PH12016501083A1 (fr)
SG (1) SG11201604660VA (fr)
SV (1) SV2016005214A (fr)
TW (1) TW201607563A (fr)
WO (1) WO2015086491A1 (fr)

Families Citing this family (24)

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Publication number Priority date Publication date Assignee Title
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
WO2015086489A1 (fr) 2013-12-11 2015-06-18 Merck Sharp & Dohme B.V. Système de délivrance de médicament pour la délivrance d'antiviraux
WO2015094759A1 (fr) 2013-12-19 2015-06-25 The Procter & Gamble Company Façonnage de fibres de kératine utilisant un principe actif comprenant au moins deux groupes fonctionnels choisis entre -c(oh)- et -c(=o)oh
EP3082735B1 (fr) 2013-12-19 2018-05-02 The Procter and Gamble Company Formage de fibres de kératine au moyen d'acide oxo-éthanoïque et/ou de dérivés de celui-ci
MX361100B (es) 2013-12-19 2018-11-27 Procter & Gamble Modelado de fibras de queratina mediante el uso de un azucar.
MX376963B (es) 2013-12-19 2025-03-07 Procter & Gamble Modelado de fibras de queratina mediante el uso de éster de carbonato.
CN105828786B (zh) 2013-12-19 2020-07-07 宝洁公司 使用包含选自-c(＝o)-、-c(＝o)-h和-c(＝o)-o-的官能团的an活性剂使角蛋白纤维成形
EP3082750A1 (fr) 2013-12-19 2016-10-26 The Procter & Gamble Company Mise en forme de fibres de kératine au moyen d'une composition réductrice et d'une composition de fixation
MX357743B (es) 2013-12-19 2018-07-23 Procter & Gamble Formacion de fibras de queratina con 2-hidroxipropano-1,2,3-acido tricarboxilico y/o 1,2,3,4-acido butanetetracarboxilico.
EP3017809A1 (fr) * 2014-11-07 2016-05-11 Ferring B.V. Unité de dispositif de médicaments contenant de la quinagolide
EP3297731A1 (fr) 2014-12-19 2018-03-28 The Procter and Gamble Company Modelage de fibres de kératine à l'aide d'arabinose et de carbonate d'éthylène
EP3297730A1 (fr) 2014-12-19 2018-03-28 The Procter and Gamble Company Procédé de mise en forme de fibres de kératine
US10945931B2 (en) 2015-06-18 2021-03-16 The Procter And Gamble Company Shaping keratin fibres using dialdehyde compounds
US20180228942A1 (en) * 2015-08-11 2018-08-16 Ptt Holding Aps A delivery device
EP3395335A1 (fr) * 2017-04-24 2018-10-31 Kern Pharma, S.L. Anneau vaginal pour la libération simultanée de deux principes actifs
DE102017113166A1 (de) * 2017-06-14 2018-12-20 Amw Gmbh Depotform zur Abgabe eines Östrogen-Wirkstoffs
EP3803866A4 (fr) 2018-05-24 2022-03-16 Nureva Inc. Procédé, appareil et supports lisibles par ordinateur pour gérer des sources sonores semi-constantes (persistantes) dans des zones de capture/foyer de microphones
MX2020012459A (es) 2018-05-24 2021-04-28 Celanese Eva Performance Polymers Llc Dispositivo implantable para liberacion sostenida de un compuesto de farmaco macromolecular.
KR20260007295A (ko) 2018-05-24 2026-01-13 셀라니즈 이브이에이 퍼포먼스 폴리머스 엘엘씨 거대 분자 약물 화합물의 지속적인 방출을 위한 이식가능 장치
US10918649B2 (en) 2019-06-21 2021-02-16 The Population Council, Inc. System for providing birth control
BR112023022439A2 (pt) 2021-04-26 2023-12-26 Celanese Eva Performance Polymers Llc Dispositivo implantável para liberação sustentada de um composto de fármaco macromolecular
EP4215180A1 (fr) * 2022-01-21 2023-07-26 Sever Pharma Solutions Système d'administration de médicaments
EP4465939A4 (fr) * 2022-01-21 2026-01-07 The Population Council Inc Anneaux intravaginaux de thérapie combinée
WO2024115763A1 (fr) 2022-12-02 2024-06-06 Vari Bioscience Gmbh Anneau vaginal libérant de l'estriol

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EP0162492B1 (fr) 1984-04-11 1989-08-02 Thiemann Arzneimittel GmbH Unités de dosage pour la libération contrôlée d'une substance active
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Also Published As

Publication number Publication date
EP3079660B1 (fr) 2021-03-03
AU2014363724A1 (en) 2016-05-26
PH12016501083A1 (en) 2016-07-25
SV2016005214A (es) 2016-11-21
CN105979930B (zh) 2019-11-19
US10413504B2 (en) 2019-09-17
HK1224208A1 (zh) 2017-08-18
PE20160680A1 (es) 2016-07-31
US20150157561A1 (en) 2015-06-11
DOP2016000132A (es) 2016-07-31
CA2931559A1 (fr) 2015-06-18
JP6251396B2 (ja) 2017-12-20
BR112016013325B1 (pt) 2022-11-29
AU2014363724B2 (en) 2017-02-23
SG11201604660VA (en) 2016-07-28
MX2016007681A (es) 2016-10-14
EA201691193A1 (ru) 2016-09-30
WO2015086491A1 (fr) 2015-06-18
IL245544A0 (en) 2016-06-30
EA031802B1 (ru) 2019-02-28
EP3079660A1 (fr) 2016-10-19
JP2016539991A (ja) 2016-12-22
CN105979930A (zh) 2016-09-28
CR20160261A (es) 2016-08-16
BR112016013325A2 (fr) 2017-08-08
MD20160079A2 (ro) 2016-10-31
TW201607563A (zh) 2016-03-01
KR101808977B1 (ko) 2017-12-13
AP2016009223A0 (en) 2016-05-31
KR20160095110A (ko) 2016-08-10
CA2931559C (fr) 2018-03-13

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