MA39481A - Thérapies ciblées - Google Patents
Thérapies cibléesInfo
- Publication number
- MA39481A MA39481A MA039481A MA39481A MA39481A MA 39481 A MA39481 A MA 39481A MA 039481 A MA039481 A MA 039481A MA 39481 A MA39481 A MA 39481A MA 39481 A MA39481 A MA 39481A
- Authority
- MA
- Morocco
- Prior art keywords
- targeted therapies
- therapies
- targeted
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/545—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Immunology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461947108P | 2014-03-03 | 2014-03-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA39481A true MA39481A (fr) | 2015-09-11 |
Family
ID=54055980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA039481A MA39481A (fr) | 2014-03-03 | 2015-03-03 | Thérapies ciblées |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10232049B2 (fr) |
| EP (1) | EP3129064B1 (fr) |
| JP (2) | JP6576942B6 (fr) |
| KR (1) | KR20160126078A (fr) |
| CN (1) | CN106456795A (fr) |
| AU (1) | AU2015224576A1 (fr) |
| CA (1) | CA2941618A1 (fr) |
| IL (1) | IL247624A0 (fr) |
| MA (1) | MA39481A (fr) |
| WO (1) | WO2015134464A2 (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015143004A1 (fr) | 2014-03-18 | 2015-09-24 | Synta Pharmaceuticals Corp. | Agents thérapeutiques cibles |
| IL318681A (en) | 2016-10-11 | 2025-03-01 | Arvinas Operations Inc | Compounds and methods for targeted reduction of androgen receptor |
| US11377447B2 (en) * | 2017-06-20 | 2022-07-05 | Madrigal Pharmaceuticals, Inc. | Targeted therapeutics |
| KR20200016874A (ko) * | 2017-06-20 | 2020-02-17 | 마드리갈 파마슈티칼스 인코포레이티드 | 표적화 치료제를 포함하는 병용 요법 |
| EP3641767A4 (fr) * | 2017-06-20 | 2021-03-10 | Tarveda Therapeutics, Inc. | Polythérapies comprenant des agents thérapeutiques ciblés |
| CN109512821B (zh) * | 2017-09-18 | 2021-06-08 | 无锡富泽药业有限公司 | 一种克唑替尼与17-aag复合聚合物纳米胶束注射剂、其制备方法及其应用 |
| EP3723811A4 (fr) * | 2017-12-14 | 2021-09-01 | Tarveda Therapeutics, Inc. | Conjugués ciblant hsp90 et formulations de ces derniers |
| CN112566666A (zh) | 2018-05-14 | 2021-03-26 | 努瓦申生物公司 | 靶向抗癌核激素受体的化合物 |
| WO2019232366A1 (fr) * | 2018-06-01 | 2019-12-05 | Tarveda Therapeutics, Inc. | Polythérapie |
| CN109575044A (zh) * | 2018-12-21 | 2019-04-05 | 西安交通大学 | 2-(喜树碱-10-氧基)乙酰胺类化合物和应用 |
| CN114026106B (zh) | 2019-03-06 | 2025-01-21 | 普洛拉治疗公司 | 阿比特龙前药 |
| EP3952863A4 (fr) * | 2019-04-10 | 2023-05-03 | Dana-Farber Cancer Institute, Inc. | Agents de dégradation du récepteur 2 du facteur de croissance des fibroblastes (fgfr2) |
| JP2022532342A (ja) | 2019-05-14 | 2022-07-14 | ニューベイション・バイオ・インコーポレイテッド | 抗がん核内ホルモン受容体標的化化合物 |
| CN110003181B (zh) * | 2019-05-22 | 2020-08-28 | 北京凯恩梅格医药科技有限公司 | 一种基于克唑替尼结构的c-Met/HDAC双靶点抑制剂及其合成方法与应用 |
| EP4126833A1 (fr) * | 2020-03-23 | 2023-02-08 | Helmholtz-Zentrum für Infektionsforschung GmbH | Dérivés de n-phényl-3-mercaptopropanamide en tant qu'inhibiteurs de métallo-bêta-lactamase pour le traitement d'infections bactériennes |
| CN111499623B (zh) * | 2020-04-01 | 2022-07-08 | 南京缘聚医药科技有限公司 | 一类非核苷抗肿瘤药物的噻唑酮脲衍生物及其药物用途 |
| TW202208345A (zh) | 2020-05-09 | 2022-03-01 | 美商亞文納營運公司 | 雙官能性化合物的製造方法、該雙官能性化合物的超純形式、及含彼之劑型 |
| MX2023008296A (es) | 2021-01-13 | 2023-09-29 | Monte Rosa Therapeutics Inc | Compuestos de isoindolinona. |
| WO2022174134A1 (fr) | 2021-02-15 | 2022-08-18 | Propella Therapeutics, Inc. | Promédicaments d'abiratérone |
| TW202304928A (zh) | 2021-03-23 | 2023-02-01 | 美商諾維雪碧歐公司 | 抗癌核荷爾蒙受體標靶化合物 |
| US12006314B2 (en) | 2021-05-03 | 2024-06-11 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| CN114933584B (zh) * | 2021-08-09 | 2022-12-27 | 上海贵之言医药科技有限公司 | 一种二氢-2h-异吲哚酯类化合物 |
| CN116354933B (zh) * | 2021-12-27 | 2025-06-20 | 青岛普泰科生物医药科技有限公司 | 作为雄激素受体调节剂的杂环化合物及其应用 |
| CN115650975B (zh) * | 2022-08-23 | 2024-07-02 | 四川大学华西医院 | 一种靶向降解人表皮生长因子受体2的蛋白降解靶向嵌合体化合物及其应用 |
| WO2024197429A1 (fr) * | 2023-03-24 | 2024-10-03 | 青岛普泰科生物医药科技有限公司 | Composé hétérocyclique servant de modulateur du récepteur des androgènes et utilisation d'un composé hétérocyclique |
| CN121487739A (zh) * | 2023-03-31 | 2026-02-06 | 珃诺生物医药科技(杭州)有限公司 | 用于靶向蛋白降解的方法和组合物 |
| US12496301B2 (en) | 2023-12-08 | 2025-12-16 | Arvinas Operations, Inc. | Use of androgen receptor degrader for the treatment of spinal and bulbar muscular atrophy |
| WO2025199665A1 (fr) * | 2024-03-23 | 2025-10-02 | Ranok Therapeutics (Hangzhou) Co. Ltd. | Procédés et compositions pour la dégradation ciblée de protéines |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6214345B1 (en) | 1993-05-14 | 2001-04-10 | Bristol-Myers Squibb Co. | Lysosomal enzyme-cleavable antitumor drug conjugates |
| ATE473759T1 (de) | 1998-05-22 | 2010-07-15 | Univ Leland Stanford Junior | Bifunktionelle moleküle sowie darauf basierende therapien. |
| US8617514B2 (en) | 1999-02-22 | 2013-12-31 | Georgetown University | Tumor-targeted nanodelivery systems to improve early MRI detection of cancer |
| WO2000061578A1 (fr) | 1999-04-09 | 2000-10-19 | Sloan-Kettering Institute For Cancer Research | Procedes et compositions permettant la degradation et/ou l'inhibition des tyrosine kinases appartenant a la famille her |
| AU2877202A (en) | 2000-11-02 | 2002-05-15 | Sloan Kettering Inst Cancer | Methods for enhancing the efficacy of cytotoxic agents through the use of hsp90 inhibitors |
| US7671010B2 (en) | 2002-08-30 | 2010-03-02 | The Board Of Regents Of The University Of Texas System | Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer |
| WO2003050295A2 (fr) | 2001-12-12 | 2003-06-19 | Conforma Therapeutics Corporation | Essais et mises en oeuvre permettant de determiner et de moduler une activite de liaison hsp90 |
| GB0211578D0 (en) | 2002-05-21 | 2002-06-26 | Univ Belfast | Medicaments |
| US6759416B2 (en) | 2002-08-06 | 2004-07-06 | Panorama Research, Inc. | Anticancer conjugates of camptothecin and unsaturated fatty acids |
| US7769423B2 (en) | 2002-09-11 | 2010-08-03 | Duke University | MRI imageable liposomes for the evaluation of treatment efficacy, thermal distribution, and demonstration of dose painting |
| AU2003303058A1 (en) | 2002-12-12 | 2004-07-09 | Conforma Therapeutics Corporation | Cytotoxins and diagnostic imaging agents comprising hsp90 ligands |
| EP1737825A1 (fr) | 2004-03-26 | 2007-01-03 | Van Andel Research Institute | Geldanamycine et ses derives pouvant inhiber une proliferation cancereuse et identifier de nouvelles cibles |
| RS52642B (sr) | 2004-11-18 | 2013-06-28 | Synta Pharmaceuticals Corp. | Jedinjenja triazola koja modulišu aktivnost hsp90 |
| US7834181B2 (en) | 2005-02-01 | 2010-11-16 | Slaon-Kettering Institute For Cancer Research | Small-molecule Hsp90 inhibitors |
| WO2007053792A2 (fr) | 2005-11-05 | 2007-05-10 | Amplyx Pharmaceuticals, Inc. | Amelioration des proprietes pharmacocinetiques d'inhibiteurs de proteases et d'autres medicaments |
| CA2632903C (fr) | 2005-12-02 | 2015-11-24 | Vianova Labs, Inc. | Traitement du cancer et d'autres maladies |
| GB0526615D0 (en) | 2005-12-30 | 2006-02-08 | Novartis Ag | Organic compounds |
| CA2653332A1 (fr) | 2006-05-25 | 2007-12-06 | Synta Pharmaceuticals Corp. | Composes de triazole qui modulent l'activite de la hsp90 |
| JP5599610B2 (ja) | 2006-06-30 | 2014-10-01 | スローン − ケッタリング インスティチュート フォー キャンサー リサーチ | Hsp90の阻害による神経変性疾患の処置 |
| JP5721949B2 (ja) | 2006-10-12 | 2015-05-20 | アステックス、セラピューティックス、リミテッドAstex Therapeutics Limited | 複合薬剤 |
| WO2008057246A2 (fr) | 2006-10-26 | 2008-05-15 | Synta Pharmaceuticals Corp. | Procédé de traitement de troubles inflammatoires |
| TW200901960A (en) * | 2007-03-05 | 2009-01-16 | Kyowa Hakko Kogyo Kk | Pharmaceutical composition |
| US20120003160A1 (en) | 2007-06-29 | 2012-01-05 | Amag Pharmaceuticals, Inc. | Macrophage-Enhanced MRI (MEMRI) in a Single Imaging Session |
| US20100203114A1 (en) | 2007-07-09 | 2010-08-12 | Warf - Wisconsin Alumni Research Foundation | Micelle encapsulation of therapeutic agents |
| JP2011501731A (ja) | 2007-09-10 | 2011-01-13 | ユニバーシティ オブ マサチューセッツ | ミトコンドリア標的化抗腫瘍剤 |
| US20110270151A1 (en) | 2008-09-08 | 2011-11-03 | The Methodist Hospital Research Institute | Image-guided energy deposition for targeted drug delivery |
| WO2011116181A1 (fr) | 2010-03-17 | 2011-09-22 | Caris Life Sciences, Inc. | Procédés théranostiques et diagnostiques utilisant sparc et hsp90 |
| ES3029483T3 (en) | 2008-09-17 | 2025-06-24 | Endocyte Inc | Folate receptor binding conjugates of antifolates |
| WO2010056590A2 (fr) | 2008-11-14 | 2010-05-20 | University Of Maryland, Baltimore | Conjugués de traceurs d'imagerie par résonance magnétique au 19f à utiliser en imagerie irm multichrome |
| MX2012002014A (es) * | 2009-08-17 | 2012-06-13 | Roche Glycart Ag | Inmunoconjugados dirigidos. |
| US20110268722A1 (en) | 2010-04-22 | 2011-11-03 | Siegelin Markus D | Combination therapies with mitochondrial-targeted anti-tumor agents |
| AU2011319685B2 (en) | 2010-10-22 | 2016-02-04 | Le Centre National De La Recherche Scientifique | Pochoxime conjugates useful for the treatment of HSP90 related pathologies |
| US20130331357A1 (en) * | 2011-01-11 | 2013-12-12 | Synta Pharmaceuticals Corp. | Combination therapy of hsp90 inhibitory compounds with proteasome inhibitors |
| GB201106814D0 (en) * | 2011-04-21 | 2011-06-01 | Astex Therapeutics Ltd | New compounds |
| JP2014532184A (ja) * | 2011-10-12 | 2014-12-04 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルThe University Of North Carolina At Chapel Hill | 多重化キナーゼ阻害剤ビーズ及びその使用 |
| WO2013071163A2 (fr) * | 2011-11-11 | 2013-05-16 | Millennium Pharamaceuticals, Inc. | Biomarqueurs de la sensibilité vis-à-vis d'inhibiteurs du protéasome |
| ES2581065T3 (es) * | 2012-02-23 | 2016-08-31 | Bayer Intellectual Property Gmbh | Benzotienil-pirrolotriazinas sustituidas y usos de las mismas |
| US20140079636A1 (en) * | 2012-04-16 | 2014-03-20 | Dinesh U. Chimmanamada | Targeted therapeutics |
| HK1208216A1 (en) | 2012-05-15 | 2016-02-26 | Concortis Biosystems, Corp | Drug-conjugates, conjugation methods, and uses thereof |
| CA2891280C (fr) | 2012-11-24 | 2018-03-20 | Hangzhou Dac Biotech Co., Ltd. | Lieurs hydrophiles et leurs utilisations pour la conjugaison de medicaments a des molecules se liant aux cellules |
| WO2015038649A1 (fr) | 2013-09-10 | 2015-03-19 | Synta Pharmaceuticals Corp. | Thérapeutique ciblée |
| CA2926586C (fr) | 2013-10-11 | 2020-04-07 | Mersana Therapeutics, Inc. | Echafaudage polymere fonde sur le phf pour la liberation de medicaments a cible definie |
| AU2014337317A1 (en) | 2013-10-15 | 2016-09-15 | Sorrento Therapeutics Inc. | Drug-conjugates with a targeting molecule and two different drugs |
| WO2015066053A2 (fr) | 2013-10-28 | 2015-05-07 | Synta Pharmaceuticals Corp. | Thérapies ciblées |
| AU2014368916B2 (en) | 2013-12-20 | 2020-04-30 | Biomed Valley Discoveries, Inc. | Cancer treatments using combinations of PI3K/Akt pathway and ERK inhibitors |
| EP3099332A4 (fr) * | 2014-01-29 | 2017-06-21 | Madrigal Pharmaceuticals, Inc. | Agents thérapeutiques cibles |
-
2015
- 2015-03-03 JP JP2016555457A patent/JP6576942B6/ja not_active Expired - Fee Related
- 2015-03-03 KR KR1020167027259A patent/KR20160126078A/ko not_active Withdrawn
- 2015-03-03 WO PCT/US2015/018442 patent/WO2015134464A2/fr not_active Ceased
- 2015-03-03 EP EP15758717.1A patent/EP3129064B1/fr active Active
- 2015-03-03 CN CN201580022696.0A patent/CN106456795A/zh active Pending
- 2015-03-03 MA MA039481A patent/MA39481A/fr unknown
- 2015-03-03 CA CA2941618A patent/CA2941618A1/fr not_active Abandoned
- 2015-03-03 AU AU2015224576A patent/AU2015224576A1/en not_active Abandoned
-
2016
- 2016-08-30 US US15/251,255 patent/US10232049B2/en active Active
- 2016-09-04 IL IL247624A patent/IL247624A0/en unknown
-
2018
- 2018-10-25 US US16/170,733 patent/US10675360B2/en not_active Expired - Fee Related
-
2019
- 2019-08-21 JP JP2019151197A patent/JP2019196406A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3129064B1 (fr) | 2020-01-01 |
| JP2017507150A (ja) | 2017-03-16 |
| EP3129064A2 (fr) | 2017-02-15 |
| EP3129064A4 (fr) | 2017-10-25 |
| US10675360B2 (en) | 2020-06-09 |
| US20170049899A1 (en) | 2017-02-23 |
| CA2941618A1 (fr) | 2015-09-11 |
| JP6576942B2 (ja) | 2019-09-18 |
| AU2015224576A1 (en) | 2016-09-22 |
| CN106456795A (zh) | 2017-02-22 |
| JP6576942B6 (ja) | 2019-11-27 |
| US20190060478A1 (en) | 2019-02-28 |
| IL247624A0 (en) | 2016-11-30 |
| JP2019196406A (ja) | 2019-11-14 |
| WO2015134464A2 (fr) | 2015-09-11 |
| KR20160126078A (ko) | 2016-11-01 |
| US10232049B2 (en) | 2019-03-19 |
| WO2015134464A3 (fr) | 2015-10-29 |
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