MA39929A - Comprimé multicouche comprenant de la metformine et du pioglitazone - Google Patents
Comprimé multicouche comprenant de la metformine et du pioglitazoneInfo
- Publication number
- MA39929A MA39929A MA039929A MA39929A MA39929A MA 39929 A MA39929 A MA 39929A MA 039929 A MA039929 A MA 039929A MA 39929 A MA39929 A MA 39929A MA 39929 A MA39929 A MA 39929A
- Authority
- MA
- Morocco
- Prior art keywords
- pioglitazone
- tablet containing
- layer tablet
- containing metformin
- layer
- Prior art date
Links
- 229940035736 metformin and pioglitazone Drugs 0.000 title 1
- 239000010410 layer Substances 0.000 abstract 2
- GHUUBYQTCDQWRA-UHFFFAOYSA-N Pioglitazone hydrochloride Chemical compound Cl.N1=CC(CC)=CC=C1CCOC(C=C1)=CC=C1CC1C(=O)NC(=O)S1 GHUUBYQTCDQWRA-UHFFFAOYSA-N 0.000 abstract 1
- 239000011247 coating layer Substances 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229960004329 metformin hydrochloride Drugs 0.000 abstract 1
- OETHQSJEHLVLGH-UHFFFAOYSA-N metformin hydrochloride Chemical compound Cl.CN(C)C(=N)N=C(N)N OETHQSJEHLVLGH-UHFFFAOYSA-N 0.000 abstract 1
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin hydrochloride Natural products CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 abstract 1
- 229960002827 pioglitazone hydrochloride Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention concerne un comprimé multicouche comprenant un noyau comprenant du chlorhydrate de metformine, une couche de libération contrôlée, d'une couche inerte et d'un chlorhydrate de pioglitazone couche de revêtement comprenant. Le comprimé multicouche est administré une fois par jour à un être humain dans le traitement de la maladie du diabète sucré.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR201414137 | 2014-11-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA39929A true MA39929A (fr) | 2016-06-01 |
Family
ID=52737379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA039929A MA39929A (fr) | 2014-11-27 | 2015-11-26 | Comprimé multicouche comprenant de la metformine et du pioglitazone |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP3025707A1 (fr) |
| MA (1) | MA39929A (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201828932A (zh) * | 2016-11-09 | 2018-08-16 | 美商諾沃麥迪斯有限責任公司 | 1,1-二甲基雙胍之亞硝酸鹽、醫藥組合物及使用方法 |
| CA3107945A1 (fr) * | 2018-08-02 | 2020-02-06 | Hospital Sant Joan De Deu | Formulation a liberation immediate d'une triple combinaison d'ingredients pharmaceutiques actifs utile dans le traitement du syndrome des ovaires polykystiques |
| CN114469896B (zh) * | 2020-10-26 | 2024-11-08 | 江苏万邦生化医药集团有限责任公司 | 一种盐酸二甲双胍缓释恩格列净速释微丸及其制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3174901A (en) | 1963-01-31 | 1965-03-23 | Jan Marcel Didier Aron Samuel | Process for the oral treatment of diabetes |
| AR240698A1 (es) | 1985-01-19 | 1990-09-28 | Takeda Chemical Industries Ltd | Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales |
| DE69100282T3 (de) | 1990-02-09 | 2001-01-11 | Pharmacia & Upjohn Co., Kalamazoo | Verwendung insulin-sensiblisierender wirkstoffe zur behandlung von hypertonie. |
| EA003101B1 (ru) | 1998-03-19 | 2002-12-26 | Бристол-Майерз Сквибб Компани | Двухфазная система доставки с регулируемым высвобождением для фармацевтических средств с высокой растворимостью и способ лечения диабета с помощью этой системы |
| EP1515701B1 (fr) | 2002-06-17 | 2014-09-17 | Inventia Healthcare Private Limited | Procédé de fabrication de comprimés multicouches comprenant de la thiazolidinedione et du biguanide |
| JP4694841B2 (ja) * | 2002-09-20 | 2011-06-08 | アンドルックス ラボズ リミテッド ライアビリティ カンパニー | ビグアニドおよびチアゾリジンジオン誘導体を含有する多段階製剤 |
| US9060941B2 (en) * | 2002-09-20 | 2015-06-23 | Actavis, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US20120093878A1 (en) * | 2010-07-30 | 2012-04-19 | Ranbaxy Laboratories Limited | Pharmaceutical compositions containing a biguanide and a thiazolidinedione |
| US20130251795A1 (en) * | 2010-07-30 | 2013-09-26 | Ranbaxy Laboratories Limited | Pharmaceutical compositions containing a biguanide and a low dose antidiabetic agent |
| JP2013538807A (ja) * | 2010-09-01 | 2013-10-17 | ルピン・リミテッド | メトホルミンおよびピオグリタゾンを含む医薬組成物 |
| CN102008472B (zh) * | 2010-10-18 | 2012-08-22 | 中国科学院上海药物研究所 | 一种复方盐酸吡格列酮/盐酸二甲双胍双层渗透泵控释制剂及其制备方法 |
| EP2638898A1 (fr) * | 2012-03-16 | 2013-09-18 | Sanovel Ilac Sanayi ve Ticaret A.S. | Formulation de pioglitazone et metformine avec différents profils de libération |
-
2015
- 2015-11-26 MA MA039929A patent/MA39929A/fr unknown
- 2015-11-26 EP EP15196487.1A patent/EP3025707A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP3025707A1 (fr) | 2016-06-01 |
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