PL376577A1 - Wielowarstwowe tabletki zawierające tiazolidinedion i biguanidy oraz metody ich wytwarzania - Google Patents
Wielowarstwowe tabletki zawierające tiazolidinedion i biguanidy oraz metody ich wytwarzaniaInfo
- Publication number
- PL376577A1 PL376577A1 PL376577A PL37657702A PL376577A1 PL 376577 A1 PL376577 A1 PL 376577A1 PL 376577 A PL376577 A PL 376577A PL 37657702 A PL37657702 A PL 37657702A PL 376577 A1 PL376577 A1 PL 376577A1
- Authority
- PL
- Poland
- Prior art keywords
- biguanides
- producing
- methods
- tablets containing
- multilayer tablets
- Prior art date
Links
- ZOBPZXTWZATXDG-UHFFFAOYSA-N 1,3-thiazolidine-2,4-dione Chemical compound O=C1CSC(=O)N1 ZOBPZXTWZATXDG-UHFFFAOYSA-N 0.000 title 1
- 229940123208 Biguanide Drugs 0.000 title 1
- 229940123464 Thiazolidinedione Drugs 0.000 title 1
- 150000004283 biguanides Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN533MU2002 | 2002-06-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL376577A1 true PL376577A1 (pl) | 2006-01-09 |
Family
ID=29727210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL376577A PL376577A1 (pl) | 2002-06-17 | 2002-10-14 | Wielowarstwowe tabletki zawierające tiazolidinedion i biguanidy oraz metody ich wytwarzania |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8911781B2 (pl) |
| EP (1) | EP1515701B1 (pl) |
| KR (1) | KR100897890B1 (pl) |
| AU (1) | AU2002356419A1 (pl) |
| PL (1) | PL376577A1 (pl) |
| WO (1) | WO2003105809A1 (pl) |
Families Citing this family (37)
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| US20040102486A1 (en) * | 1998-11-12 | 2004-05-27 | Smithkline Beecham Corporation | Novel method of treatment |
| US20030153607A1 (en) * | 1998-11-12 | 2003-08-14 | Smithkline Beecham P.L.C. | Novel composition and use |
| US9060941B2 (en) | 2002-09-20 | 2015-06-23 | Actavis, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US7959946B2 (en) | 2002-09-20 | 2011-06-14 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US8084058B2 (en) * | 2002-09-20 | 2011-12-27 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US7785627B2 (en) * | 2002-09-20 | 2010-08-31 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| WO2004067001A1 (ja) | 2003-01-29 | 2004-08-12 | Takeda Pharmaceutical Company Limited | 被覆製剤の製造法 |
| US20060280794A1 (en) * | 2003-06-06 | 2006-12-14 | Naoru Hamaguchi | Solid pharmaceutical preparation |
| DE60331236D1 (de) * | 2003-07-24 | 2010-03-25 | Eswaran Krishnan Iyer | Orale zusammensetzungen zur behandlung von diabetes |
| US20070191815A1 (en) | 2004-09-13 | 2007-08-16 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery |
| WO2005092293A1 (en) * | 2004-03-22 | 2005-10-06 | Ranbaxy Laboratories Limited | Formulations of metformin |
| BRPI0612802A2 (pt) | 2005-07-07 | 2010-11-30 | Farnam Co Inc | composições farmacêuticas de liberação sustentada para medicamentos extremamente hidrossolúveis |
| EP1970055B1 (en) | 2005-12-29 | 2010-11-24 | Osmotica Kereskedelmi És Szolgáltató Kft | Multi-layered tablet with triple release combination |
| EP1977746B8 (en) | 2007-04-02 | 2014-09-24 | Parkinson's Institute | Methods and compositions for reduction of side effects of therapeutic treatments |
| KR101107432B1 (ko) * | 2007-04-13 | 2012-01-19 | 주식회사 한독약품 | 반투과성 막에 수용성 활성성분을 포함하는 서방형약제학적 조성물 |
| US20080286344A1 (en) * | 2007-05-16 | 2008-11-20 | Olivia Darmuzey | Solid form |
| US20110009347A1 (en) | 2009-07-08 | 2011-01-13 | Yin Liang | Combination therapy for the treatment of diabetes |
| CA3002948C (en) | 2009-11-13 | 2020-10-27 | Astrazeneca Uk Limited | Immediate release tablet formulations |
| AU2014218385B2 (en) * | 2009-11-13 | 2016-02-25 | Astrazeneca Ab | Bilayer tablet formulations |
| CN102711739B (zh) | 2009-11-13 | 2015-12-16 | 阿斯利康(瑞典)有限公司 | 双层片剂 |
| BR112012011274A2 (pt) * | 2009-11-13 | 2016-04-12 | Astrazeneca Uk Ltd | formulação de metformina de massa reduzida e sua combinação |
| KR101248804B1 (ko) * | 2010-05-14 | 2013-03-29 | 한미사이언스 주식회사 | HMG-CoA 환원효소 억제제 및 이베살탄을 포함하는 이층정 약제학적 복합제제 |
| US20120093878A1 (en) * | 2010-07-30 | 2012-04-19 | Ranbaxy Laboratories Limited | Pharmaceutical compositions containing a biguanide and a thiazolidinedione |
| EP2611434A1 (en) | 2010-09-01 | 2013-07-10 | Lupin Limited | Pharmaceutical composition comprising metformin and pioglitazone |
| WO2013077824A1 (en) * | 2011-11-23 | 2013-05-30 | Mahmut Bilgic | Preparation process for a formulation comprising metformin |
| EP2638898A1 (en) | 2012-03-16 | 2013-09-18 | Sanovel Ilac Sanayi ve Ticaret A.S. | Metformin and Pioglitazone Formulation with Different Release Profiles |
| US10105487B2 (en) | 2013-01-24 | 2018-10-23 | Chrono Therapeutics Inc. | Optimized bio-synchronous bioactive agent delivery system |
| KR101597004B1 (ko) * | 2013-07-25 | 2016-02-23 | 씨제이헬스케어 주식회사 | 서방형 메트포르민과 속방형 HMG-CoA 환원효소 억제제를 포함하는 복합제제 |
| EP3025707A1 (en) | 2014-11-27 | 2016-06-01 | Arven Ilac Sanayi Ve Ticaret A.S. | A multilayer tablet comprising metformin and pioglitazone |
| JP2018511355A (ja) | 2015-01-28 | 2018-04-26 | クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. | 薬剤送達方法及びシステム |
| JP6860922B2 (ja) * | 2016-02-12 | 2021-04-21 | 国立大学法人 岡山大学 | 免疫機能の検査方法、がん患者の選別方法、がんの治療効果予測方法、細胞内カルシウムイオン濃度上昇剤、腫瘍組織におけるエフェクター・メモリー(EM)とエフェクター(eff)の選択的機能向上剤、がん治療薬の効果のモニタリング方法 |
| CA2937365C (en) | 2016-03-29 | 2018-09-18 | F. Hoffmann-La Roche Ag | Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same |
| WO2018129304A1 (en) | 2017-01-06 | 2018-07-12 | Chrono Therapeutics Inc. | Transdermal drug delivery devices and methods |
| AU2019279884B2 (en) | 2018-05-29 | 2025-01-30 | Morningside Venture Investments Limited | Drug delivery methods and systems |
| JP2022507660A (ja) | 2018-11-16 | 2022-01-18 | モーニングサイド ベンチャー インベストメンツ リミテッド | 温度によって調節される経皮薬剤送達システム |
| KR20230086370A (ko) | 2021-12-08 | 2023-06-15 | 주식회사 유영제약 | 다파글리플로진과 피오글리타존을 포함하는 약제학적 복합제제 및 이의 제조방법 |
| US12303604B1 (en) | 2024-10-16 | 2025-05-20 | Currax Pharmaceuticals Llc | Pharmaceutical formulations comprising naltrexone and/or bupropion |
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| US20030187074A1 (en) | 2002-03-04 | 2003-10-02 | Javed Hussain | Oral compositions for treatment of diabetes |
| US20030171407A1 (en) | 2002-03-07 | 2003-09-11 | Upsher-Smith Laboratories, Inc. | Composition for reducing blood glucose and cholesterol |
| US20030219482A1 (en) | 2002-03-21 | 2003-11-27 | Chaudhari Sunil Sudhakar | Multiparticulate compositions for once-a-day administration |
| AU2003241537A1 (en) | 2002-05-23 | 2003-12-12 | Andrx Corporation | Biguanide formulations |
| US20030224046A1 (en) | 2002-06-03 | 2003-12-04 | Vinay Rao | Unit-dose combination composition for the simultaneous delivery of a short-acting and a long-acting oral hypoglycemic agent |
| US6830759B2 (en) | 2002-06-28 | 2004-12-14 | Ajinomoto Co., Inc. | Antidiabetic preparation for oral administration |
| US7985422B2 (en) | 2002-08-05 | 2011-07-26 | Torrent Pharmaceuticals Limited | Dosage form |
| US9060941B2 (en) | 2002-09-20 | 2015-06-23 | Actavis, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US20040086566A1 (en) | 2002-11-04 | 2004-05-06 | Alpharma, Inc. | Waxy matrix dosage forms |
| WO2004082591A2 (en) | 2003-02-17 | 2004-09-30 | Sun Pharmaceutical Industries Limited | Pharmaceutical composition for treatment of diabetes mellitus |
| KR100772980B1 (ko) | 2004-04-01 | 2007-11-02 | 한미약품 주식회사 | 메트포르민의 경구투여용 서방성 제제 |
-
2002
- 2002-10-14 PL PL376577A patent/PL376577A1/pl not_active Application Discontinuation
- 2002-10-14 AU AU2002356419A patent/AU2002356419A1/en not_active Abandoned
- 2002-10-14 WO PCT/IN2002/000207 patent/WO2003105809A1/en not_active Ceased
- 2002-10-14 EP EP02807523.2A patent/EP1515701B1/en not_active Expired - Lifetime
- 2002-10-14 US US10/518,044 patent/US8911781B2/en not_active Expired - Fee Related
- 2002-10-14 KR KR1020047020533A patent/KR100897890B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002356419A1 (en) | 2003-12-31 |
| EP1515701A1 (en) | 2005-03-23 |
| KR20050016574A (ko) | 2005-02-21 |
| WO2003105809A1 (en) | 2003-12-24 |
| US20060057202A1 (en) | 2006-03-16 |
| EP1515701B1 (en) | 2014-09-17 |
| KR100897890B1 (ko) | 2009-05-18 |
| US8911781B2 (en) | 2014-12-16 |
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| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |