MA39958B1 - Procédé d'expansion de cellules souches adultes à partir de sang total - Google Patents

Procédé d'expansion de cellules souches adultes à partir de sang total

Info

Publication number
MA39958B1
MA39958B1 MA39958A MA39958A MA39958B1 MA 39958 B1 MA39958 B1 MA 39958B1 MA 39958 A MA39958 A MA 39958A MA 39958 A MA39958 A MA 39958A MA 39958 B1 MA39958 B1 MA 39958B1
Authority
MA
Morocco
Prior art keywords
stem cells
whole blood
adult stem
blood
blood sample
Prior art date
Application number
MA39958A
Other languages
English (en)
Other versions
MA39958A (fr
Inventor
Marco Polettini
Original Assignee
Thankstem S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thankstem S R L filed Critical Thankstem S R L
Publication of MA39958A publication Critical patent/MA39958A/fr
Publication of MA39958B1 publication Critical patent/MA39958B1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/40Peroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/02Atmosphere, e.g. low oxygen conditions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/22Colony stimulating factors (G-CSF, GM-CSF)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Procédé d'expansion de cellules souches adultes à partir de sang comprenant la culture et la déprogrammation des cellules souches de sang adultes d'un échantillon de sang pris lors d'un traitement in vitro de l'échantillon de sang par mcsf et ozonisation de l'échantillon de sang.
MA39958A 2014-05-09 2015-05-08 Procédé d'expansion de cellules souches adultes à partir de sang total MA39958B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITUD20140075 2014-05-09
PCT/IB2015/053379 WO2015170291A1 (fr) 2014-05-09 2015-05-08 Procédé d'expansion de cellules souches adultes à partir de sang total

Publications (2)

Publication Number Publication Date
MA39958A MA39958A (fr) 2017-03-15
MA39958B1 true MA39958B1 (fr) 2018-10-31

Family

ID=51136668

Family Applications (1)

Application Number Title Priority Date Filing Date
MA39958A MA39958B1 (fr) 2014-05-09 2015-05-08 Procédé d'expansion de cellules souches adultes à partir de sang total

Country Status (21)

Country Link
US (1) US20170152482A1 (fr)
EP (1) EP3140396B1 (fr)
JP (1) JP6664382B2 (fr)
KR (1) KR20170002568A (fr)
CN (1) CN106574247A (fr)
AR (1) AR101442A1 (fr)
AU (1) AU2015257334B2 (fr)
CA (1) CA2948096A1 (fr)
DK (1) DK3140396T3 (fr)
EA (1) EA035104B1 (fr)
ES (1) ES2690253T3 (fr)
HR (1) HRP20181542T1 (fr)
HU (1) HUE040661T2 (fr)
IL (1) IL248805A0 (fr)
MA (1) MA39958B1 (fr)
MX (1) MX369097B (fr)
PL (1) PL3140396T3 (fr)
RS (1) RS57793B1 (fr)
SG (1) SG11201609306UA (fr)
SI (1) SI3140396T1 (fr)
WO (1) WO2015170291A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020277774A1 (en) * 2019-05-22 2021-12-09 Thankstem S.R.L. Method for expanding adult stem cells from whole blood
JP2022078971A (ja) * 2020-11-13 2022-05-25 レネロファーマ株式会社 皮膚炎及び皮膚状態改善用オゾンバブリング装置及び皮膚炎及び皮膚状態改善方法
JP7403771B2 (ja) * 2020-11-13 2023-12-25 レネロファーマ株式会社 外傷性炎症改善用オゾンバブリング装置及び外傷性炎症改善方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1243278E (pt) * 1992-02-07 2007-04-30 Vasogen Ireland Ltd Utilização de sangue tendo uma concentração aumentada de óxido nítrico para o fabrico de um medicamento
US5591457A (en) * 1992-02-07 1997-01-07 Vasogen Inc Method of inhibiting the aggregation of blood platelets and stimulating the immune systems of a human
TWI288779B (en) 2002-03-28 2007-10-21 Blasticon Biotech Forschung Dedifferentiated, programmable stem cells of monocytic origin, and their production and use
US20040136973A1 (en) 2002-11-07 2004-07-15 Eliezer Huberman Human stem cell materials and methods
EP2357223A3 (fr) 2002-11-07 2012-11-07 University Of Chicago CELLULES SOUCHES HUMAINES et PROCÉDÉ DE UTILISATION
CA2651331A1 (fr) 2006-05-05 2007-11-15 Opexa Therapeutics Cellules souches derivees de monocytes
CN100471085C (zh) 2006-08-22 2009-03-18 华为技术有限公司 上行物理信道的功率控制方法及装置
ITRM20060498A1 (it) * 2006-09-20 2008-03-21 Alessandra Gambacurta Metodo di espansione di cellule staminali adulte da sangue periferico e relativi usi in campo medico
WO2008036374A2 (fr) 2006-09-21 2008-03-27 Medistem Laboratories, Inc. Allogreffes de cellules souches chez des receveurs non conditionnes
WO2009046377A2 (fr) * 2007-10-04 2009-04-09 Medistem Laboratories, Inc. Compositions et procédés de thérapie par cellules souches pour l'autisme
ITUD20080058A1 (it) * 2008-03-18 2009-09-19 Thankstem S R L Kit per la raccolta di sangue, preferibilmente periferico, per la produzione di cellule staminali

Also Published As

Publication number Publication date
IL248805A0 (en) 2017-01-31
PL3140396T3 (pl) 2019-01-31
KR20170002568A (ko) 2017-01-06
EP3140396B1 (fr) 2018-08-01
HRP20181542T1 (hr) 2018-11-30
AU2015257334B2 (en) 2021-02-25
JP2017521088A (ja) 2017-08-03
MX2016014628A (es) 2017-05-02
EA035104B1 (ru) 2020-04-28
EA201650059A1 (ru) 2017-05-31
MA39958A (fr) 2017-03-15
EP3140396A1 (fr) 2017-03-15
DK3140396T3 (en) 2018-11-12
HUE040661T2 (hu) 2019-03-28
RS57793B1 (sr) 2018-12-31
ES2690253T3 (es) 2018-11-20
US20170152482A1 (en) 2017-06-01
SI3140396T1 (sl) 2018-11-30
JP6664382B2 (ja) 2020-03-13
WO2015170291A1 (fr) 2015-11-12
CA2948096A1 (fr) 2015-11-12
AU2015257334A1 (en) 2016-12-15
AR101442A1 (es) 2016-12-21
SG11201609306UA (en) 2016-12-29
CN106574247A (zh) 2017-04-19
MX369097B (es) 2019-10-29

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