MA40403A - Méthodes de traitement de paramyxovirus - Google Patents

Méthodes de traitement de paramyxovirus

Info

Publication number
MA40403A
MA40403A MA040403A MA40403A MA40403A MA 40403 A MA40403 A MA 40403A MA 040403 A MA040403 A MA 040403A MA 40403 A MA40403 A MA 40403A MA 40403 A MA40403 A MA 40403A
Authority
MA
Morocco
Prior art keywords
treating
methods
paramyxoviruses
methylpropanoate
cytidine
Prior art date
Application number
MA040403A
Other languages
English (en)
Inventor
Lawrence M Blatt
Sushmita Mukherjee Chanda
John Fry
Qingling Zhang
Original Assignee
Alios Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alios Biopharma Inc filed Critical Alios Biopharma Inc
Publication of MA40403A publication Critical patent/MA40403A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

La présente invention concerne des procédés pour l'amélioration et/ou le traitement d'une infection à paramyxovirus, ou l'inhibition de la réplication d'un paramyxovirus, par l'utilisation de 3',5'-(2-méthylpropanoate-4'-c-(chlorométhyl)-2'-désoxy-2'-fluoro-cytidine (composé a)), le composé (a) ou son sel pharmaceutiquement acceptable pouvant fournir 4'-c-chlorométhyl-2'-désoxy-2'-fluoro-5'- (tétrahydrogène triphosphate)-cytidine ou son sel pharmaceutiquement acceptable (composé (b)).
MA040403A 2014-07-22 2015-07-20 Méthodes de traitement de paramyxovirus MA40403A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462027719P 2014-07-22 2014-07-22

Publications (1)

Publication Number Publication Date
MA40403A true MA40403A (fr) 2017-05-31

Family

ID=55163588

Family Applications (1)

Application Number Title Priority Date Filing Date
MA040403A MA40403A (fr) 2014-07-22 2015-07-20 Méthodes de traitement de paramyxovirus

Country Status (13)

Country Link
US (1) US20160022724A1 (fr)
EP (1) EP3171878A4 (fr)
JP (1) JP2017525681A (fr)
KR (1) KR20170031231A (fr)
AU (1) AU2015294343A1 (fr)
BR (1) BR112017001162A2 (fr)
CA (1) CA2955604A1 (fr)
CL (1) CL2017000156A1 (fr)
MA (1) MA40403A (fr)
MX (1) MX2017000983A (fr)
RU (1) RU2017105470A (fr)
TW (1) TW201609104A (fr)
WO (1) WO2016014398A1 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201610936RA (en) 2011-12-22 2017-02-27 Alios Biopharma Inc Substituted nucleosides, nucleotides and analogs thereof
US8980865B2 (en) 2011-12-22 2015-03-17 Alios Biopharma, Inc. Substituted nucleotide analogs
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
US8916538B2 (en) 2012-03-21 2014-12-23 Vertex Pharmaceuticals Incorporated Solid forms of a thiophosphoramidate nucleotide prodrug
US9598457B2 (en) 2012-12-21 2017-03-21 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
GEP201706757B (en) 2012-12-21 2017-10-25 Alios Biopharma Inc Substituted nucleosides, nucleotides and analogs thereof
AU2014248116A1 (en) 2013-04-05 2015-11-12 Alios Biopharma, Inc. Hepatitis C viral infection treatment using a combination of compounds
EP3424938B1 (fr) 2013-06-26 2020-07-22 Janssen BioPharma, Inc. Nucléosides, nucléotides et leurs analogues substitués par 4'-azidoalkyl
HK1224229A1 (zh) 2013-06-26 2017-08-18 Alios Biopharma, Inc. 取代的核苷，核苷酸及其类似物
JP6562908B2 (ja) 2013-10-11 2019-08-21 ヤンセン バイオファーマ インク． 置換ヌクレオシド、置換ヌクレオチドおよびその類似体
HUE051986T2 (hu) 2014-06-24 2021-04-28 Janssen Biopharma Inc Helyettesített nukleozidok, nukleotidek és analógjaik virális fertõzés kezelésére való alkalmazásra
TN2016000566A1 (en) 2014-06-24 2018-04-04 Alios Biopharma Inc Substituted nucleosides, nucleotides and analogs thereof
JP2017523988A (ja) * 2014-08-05 2017-08-24 アリオス バイオファーマ インク． パラミクソウイルスを治療するための併用療法
HK1243714A1 (zh) 2014-10-28 2018-07-20 Alios Biopharma, Inc. 制备取代的核苷类似物的方法
MA41441A (fr) 2014-12-19 2017-12-12 Alios Biopharma Inc Nucléosides substitués, nucléotides et analogues de ceux-ci
MA41213A (fr) 2014-12-19 2017-10-24 Alios Biopharma Inc Nucléosides substitués, nucléotides et analogues de ceux-ci
EA036776B1 (ru) 2015-03-11 2020-12-21 Янссен Байофарма, Инк. Соединения азапиридона и способы их применения
WO2018081449A1 (fr) * 2016-10-27 2018-05-03 Alios Biopharma, Inc. Méthode pour le traitement d'une infection par le virus respiratoire syncytial
WO2018222774A1 (fr) * 2017-05-30 2018-12-06 Alios Biopharma, Inc. Méthodes de traitement des pneumovirus
CN113462656B (zh) * 2021-03-24 2022-09-30 兰州生物制品研究所有限责任公司 一种人三型副流感病毒冷适应温度敏感株及其应用
EP4493573A1 (fr) 2022-03-15 2025-01-22 Rome Therapeutics, Inc. Composés et méthodes pour traiter une maladie

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ244102A (en) * 1991-08-26 1996-12-20 Scripps Research Inst Peptides inducing cytotoxic t lymphocyte responses against hbv antigen and their use
JPH0859508A (ja) * 1994-08-16 1996-03-05 Teijin Ltd サイトメガロウイルス網膜炎予防または治療剤
MX2012015292A (es) * 2010-06-24 2013-05-30 Gilead Sciences Inc Pirazolo[1, 5]pirimidinas en la forma de agentes antivirales.
SG10201610936RA (en) * 2011-12-22 2017-02-27 Alios Biopharma Inc Substituted nucleosides, nucleotides and analogs thereof
RS58437B1 (sr) * 2012-03-21 2019-04-30 Alios Biopharma Inc Supstituisani nukleozidi, nukleotidi i njihovi analozi

Also Published As

Publication number Publication date
KR20170031231A (ko) 2017-03-20
AU2015294343A1 (en) 2017-02-02
MX2017000983A (es) 2017-09-01
EP3171878A4 (fr) 2018-03-14
CA2955604A1 (fr) 2016-01-28
CL2017000156A1 (es) 2017-11-03
BR112017001162A2 (pt) 2017-11-14
TW201609104A (zh) 2016-03-16
RU2017105470A (ru) 2018-08-22
RU2017105470A3 (fr) 2019-02-28
US20160022724A1 (en) 2016-01-28
JP2017525681A (ja) 2017-09-07
WO2016014398A1 (fr) 2016-01-28
EP3171878A1 (fr) 2017-05-31

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