MA41387A1 - Production of oversized adeno-associated vectors - Google Patents

Production of oversized adeno-associated vectors

Info

Publication number
MA41387A1
MA41387A1 MA41387A MA41387A MA41387A1 MA 41387 A1 MA41387 A1 MA 41387A1 MA 41387 A MA41387 A MA 41387A MA 41387 A MA41387 A MA 41387A MA 41387 A1 MA41387 A1 MA 41387A1
Authority
MA
Morocco
Prior art keywords
oversized
adeno
production
relates
aav
Prior art date
Application number
MA41387A
Other languages
French (fr)
Other versions
MA41387B1 (en
Inventor
Sirkka Kyostio-Moore
David Souza
Karen Vincent
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Priority claimed from PCT/US2016/026486 external-priority patent/WO2016164609A2/en
Publication of MA41387A1 publication Critical patent/MA41387A1/en
Publication of MA41387B1 publication Critical patent/MA41387B1/en

Links

Landscapes

  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne des méthodes de production d'une particule de virus adéno-associé (aav) comprenant un génome aav recombinant surdimensionné (par exemple, supérieur à 4,7 kb). Dans certains aspects, l'invention concerne des particules aav et des vecteurs aav comprenant des génomes aavr surdimensionnés. L'invention concerne également des lignées cellulaires productrices pour produire des particules aav comprenant des génomes surdimensionnés.The present invention relates to methods for producing an adeno-associated virus (aav) particle comprising an oversized recombinant αv genome (e.g., greater than 4.7 kb). In some aspects, the invention relates to aav particles and aav vectors comprising oversized aavr genomes. The invention also relates to producing cell lines for producing aav particles comprising oversized genomes.

MA41387A 2015-04-08 2016-04-07 Production of oversized adeno-associated vectors MA41387B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562144862P 2015-04-08 2015-04-08
PCT/US2016/026486 WO2016164609A2 (en) 2015-04-08 2016-04-07 Production of oversized adeno-associated vectors

Publications (2)

Publication Number Publication Date
MA41387A1 true MA41387A1 (en) 2018-10-31
MA41387B1 MA41387B1 (en) 2021-04-30

Family

ID=59487577

Family Applications (1)

Application Number Title Priority Date Filing Date
MA41387A MA41387B1 (en) 2015-04-08 2016-04-07 Production of oversized adeno-associated vectors

Country Status (2)

Country Link
AR (1) AR104216A1 (en)
MA (1) MA41387B1 (en)

Also Published As

Publication number Publication date
AR104216A1 (en) 2017-07-05
MA41387B1 (en) 2021-04-30

Similar Documents

Publication Publication Date Title
PH12017501836A1 (en) Production of oversized adeno-associated vectors
WO2018204803A8 (en) Compositions and methods of treating huntington's disease
PH12018500594A1 (en) Adeno-associated virus factor viii vectors, associated viral particles and therapeutic formulations comprising the same
WO2017066764A3 (en) Modification of n-terminal region of capsid proteins for enhanced properties of adeno-associated viruses
MX2023009081A (en) Methods for detecting aav.
PH12018501055A1 (en) Cpg reduced factor viii variants, compositions and methods and uses for treatment of hemostasis disorders
MX363533B (en) Fusion proteins comprising pdgf and vegf binding portions and methods of using thereof.
PE20150163A1 (en) COMPOSITION AND METHODS FOR A HIGHLY EFFICIENT GENE TRANSFER USING CAPSID AAV VARIANTS
MX2009011064A (en) Sulfur compounds as inhiibitors of hepatitis c virus ns3 serine protease.
EP4219727A3 (en) Products and methods for treatment of amyotrophic lateral sclerosis
MX388264B (en) ENHANCED DELIVERY OF VIRAL PARTICLES TO THE STRIATAL CORPORATION AND CORTEX.
EA201690403A1 (en) COMPOSITIONS AND METHODS FOR RNA MODULATION
GEAP202114672A (en) Antibodies specific for hyperphosphorylated tau and methods of use thereof
EP4234691A3 (en) Engineered meganucleases specific for recognition sequences in the hepatitis b virus genome
WO2014191521A3 (en) New compact scaffold of cas9 in the type ii crispr system
WO2014145599A3 (en) Recombinant virus and preparations thereof
IN2014DN10288A (en)
IN2014KN02672A (en)
MX2020011586A (en) Synthetic chimeric vaccinia virus.
EA201992688A1 (en) MEANS, WAYS OF APPLICATION AND METHODS OF TREATMENT
WO2016119052A8 (en) Compositions and methods for enhancing oncolytic virus efficacy
SA515360200B1 (en) Hepatocyte growth factor mimics as therapeutic agents
MX2018007330A (en) Adeno-associated viral vectors for treating mucolipidosis type ii.
MA41387A1 (en) Production of oversized adeno-associated vectors
PH12017500816A1 (en) Long acting pharmaceutical compositions for hepatitis c