MA41387B1 - Production of oversized adeno-associated vectors - Google Patents

Production of oversized adeno-associated vectors

Info

Publication number
MA41387B1
MA41387B1 MA41387A MA41387A MA41387B1 MA 41387 B1 MA41387 B1 MA 41387B1 MA 41387 A MA41387 A MA 41387A MA 41387 A MA41387 A MA 41387A MA 41387 B1 MA41387 B1 MA 41387B1
Authority
MA
Morocco
Prior art keywords
oversized
adeno
aav
production
relates
Prior art date
Application number
MA41387A
Other languages
French (fr)
Other versions
MA41387A1 (en
Inventor
Sirkka Kyostio-Moore
David Souza
Karen Vincent
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Priority claimed from PCT/US2016/026486 external-priority patent/WO2016164609A2/en
Publication of MA41387A1 publication Critical patent/MA41387A1/en
Publication of MA41387B1 publication Critical patent/MA41387B1/en

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Abstract

La présente invention concerne des méthodes de production d'une particule de virus adéno-associé (aav) comprenant un génome aav recombinant surdimensionné (par exemple, supérieur à 4,7 kb). Dans certains aspects, l'invention concerne des particules aav et des vecteurs aav comprenant des génomes aavr surdimensionnés. L'invention concerne également des lignées cellulaires productrices pour produire des particules aav comprenant des génomes surdimensionnés.The present invention relates to methods of producing an adeno-associated virus (aav) particle comprising an oversized recombinant aav genome (eg, greater than 4.7 kb). In certain aspects, the invention relates to aav particles and aav vectors comprising oversized aavr genomes. The invention also relates to producer cell lines for producing aav particles comprising oversized genomes.

MA41387A 2015-04-08 2016-04-07 Production of oversized adeno-associated vectors MA41387B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562144862P 2015-04-08 2015-04-08
PCT/US2016/026486 WO2016164609A2 (en) 2015-04-08 2016-04-07 Production of oversized adeno-associated vectors

Publications (2)

Publication Number Publication Date
MA41387A1 MA41387A1 (en) 2018-10-31
MA41387B1 true MA41387B1 (en) 2021-04-30

Family

ID=59487577

Family Applications (1)

Application Number Title Priority Date Filing Date
MA41387A MA41387B1 (en) 2015-04-08 2016-04-07 Production of oversized adeno-associated vectors

Country Status (2)

Country Link
AR (1) AR104216A1 (en)
MA (1) MA41387B1 (en)

Also Published As

Publication number Publication date
AR104216A1 (en) 2017-07-05
MA41387A1 (en) 2018-10-31

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