MA41790A - Dérivé de morphinane - Google Patents

Dérivé de morphinane

Info

Publication number: MA41790A
Authority: MA; Morocco
Prior art keywords: morphinane derivative; morphinane; derivative
Prior art date: 2015-03-17

Application number

MA041790A

Other languages

English (en)

Other versions

MA41790B1 (fr

Inventor

Hideaki Fujii

Kohei Hayashida

Masaaki Hirose

Hiroshi Nagase

Eriko Nakata

Isao Ooi

Akiyoshi Saitoh

Original Assignee

Nippon Chemiphar Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-03-17

Filing date

2016-03-17

Publication date

2021-06-02

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56919074&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA41790(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2016-03-17 Application filed by Nippon Chemiphar Co filed Critical Nippon Chemiphar Co

2021-06-02 Publication of MA41790A publication Critical patent/MA41790A/fr

2022-02-28 Publication of MA41790B1 publication Critical patent/MA41790B1/fr

Links

150000003809 morphinane derivatives Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Ophthalmology & Optometry (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Psychology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

MA41790A 2015-03-17 2016-03-17 Dérivé de morphinane MA41790B1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2015054079		2015-03-17
PCT/JP2016/058475 WO2016148232A1 (fr)	2015-03-17	2016-03-17	Dérivé de morphinane

Publications (2)

Publication Number	Publication Date
MA41790A true MA41790A (fr)	2021-06-02
MA41790B1 MA41790B1 (fr)	2022-02-28

Family

ID=56919074

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA41790A MA41790B1 (fr)	2015-03-17	2016-03-17	Dérivé de morphinane

Country Status (23)

Country	Link
US (4)	US10442802B2 (fr)
EP (2)	EP3272750B1 (fr)
JP (5)	JP6692345B2 (fr)
KR (2)	KR102813010B1 (fr)
CN (3)	CN113292558A (fr)
AU (2)	AU2016234222C1 (fr)
BR (1)	BR112017019805B1 (fr)
CA (1)	CA2979023C (fr)
CY (1)	CY1124908T1 (fr)
DK (1)	DK3272750T3 (fr)
ES (1)	ES2904511T3 (fr)
HU (1)	HUE057266T2 (fr)
IL (1)	IL254473B (fr)
MA (1)	MA41790B1 (fr)
MX (2)	MX2021008741A (fr)
MY (1)	MY197742A (fr)
PH (1)	PH12017501655B1 (fr)
PL (1)	PL3272750T3 (fr)
RU (1)	RU2762567C2 (fr)
SG (2)	SG11201707427TA (fr)
TW (2)	TWI775723B (fr)
WO (1)	WO2016148232A1 (fr)
ZA (1)	ZA201706882B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI775723B (zh) *	2015-03-17	2022-09-01	日商日本化美化股份有限公司	嗎啡喃衍生物
WO2018030382A1 (fr)	2016-08-09	2018-02-15	国立大学法人筑波大学	Dérivé de morphinane
JP6840155B6 (ja) *	2016-09-16	2025-06-17	日本ケミファ株式会社	モルヒナン誘導体のオピオイドδ受容体アゴニスト関連疾患の治療のための使用
JP7283711B2 (ja) *	2016-10-03	2023-05-30	学校法人星薬科大学	モルヒナン誘導体を含む医薬組成物及びその鎮痛剤への使用
WO2021015108A1 (fr)	2019-07-19	2021-01-28	日本ケミファ株式会社	Procédé de production d'un dérivé de morphinane
WO2021015109A1 (fr)	2019-07-19	2021-01-28	日本ケミファ株式会社	Procédé de production d'un dérivé du phénol
KR102937451B1 (ko)	2020-08-28	2026-03-10	닛뽕 케미파 가부시키가이샤	신규한 구리 촉매를 사용하여 디아릴 에테르 골격을 갖는 모르피난 유도체를 제조하는 방법
CN116997360A (zh) *	2021-02-26	2023-11-03	学校法人东京理科大学	应激相关障碍的治疗或预防用医药组合物
IL305423A (en) *	2021-02-26	2023-10-01	Univ Tokyo Science Found	Pharmaceutical composition for treatment or prevention of stress-related disorders
TW202547487A (zh) *	2024-03-18	2025-12-16	學校法人東京理科大學	失樂症的治療或預防用醫藥組成物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2005231995A (ja)	1999-12-22	2005-09-02	Meiji Seika Kaisha Ltd	オピオイドδ受容体アゴニスト／アンタゴニストとして有用なスピロ化合物
DE10161963A1 (de)	2001-12-17	2003-07-03	Johannes Schuetz	6-Aminomorphinanderivate, Herstellungsverfahren dafür und deren Verwendung
AR044010A1 (es)	2003-04-11	2005-08-24	Janssen Pharmaceutica Nv	Uso de derivados de 4-fenil-4- [1h-imidazol-2-il]- piperidina sustituidos como agonistas delta opioideos no peptidos selectivos, con actividad antidepresiva y ansiolitica
JP2008534679A (ja)	2005-04-04	2008-08-28	アストラゼネカ・アクチエボラーグ	新規ジアザスピロアルカン類およびｃｃｒ８介在疾患の処置のためのそれらの使用
WO2008001859A1 (fr)	2006-06-30	2008-01-03	School Juridical Person Kitasato Gakuen	AGONISTE DES RÉCEPTEURS δ DES OPIOÏDES
WO2009033084A1 (fr)	2007-09-06	2009-03-12	Array Biopharma Inc.	Pyrazolo-pyridines en tant qu'inhibiteurs de tyrosine kinase
US8183371B2 (en)	2009-10-30	2012-05-22	Janssen Pharmaceutica Nv	Pyrazines as delta opioid receptor modulators
US9227971B2 (en)	2010-01-19	2016-01-05	Merck Sharp & Dohme Corp.	Pyrazolo[1,5-a]pyrimidine compounds as mTOR inhibitors
US8987293B2 (en)	2010-12-23	2015-03-24	Phoenix Pharmalabs, Inc.	Morphinans useful as analgesics
JP2014073964A (ja)	2011-01-28	2014-04-24	Kitasato Institute	モルヒナン誘導体
JP6061857B2 (ja)	2011-09-09	2017-01-18	学校法人北里研究所	モルヒナン誘導体
WO2014021273A1 (fr)	2012-07-30	2014-02-06	学校法人北里研究所	Dérivés morphinane
US8937084B2 (en)	2012-12-14	2015-01-20	Purdue Pharma L.P.	Nitrogen containing morphinan derivatives and the use thereof
US9624223B2 (en)	2013-03-08	2017-04-18	The Kitasato Institute	Morphinan derivative
TWI775723B (zh) *	2015-03-17	2022-09-01	日商日本化美化股份有限公司	嗎啡喃衍生物
JP6840155B6 (ja)	2016-09-16	2025-06-17	日本ケミファ株式会社	モルヒナン誘導体のオピオイドδ受容体アゴニスト関連疾患の治療のための使用

2016
- 2016-03-17 TW TW105108248A patent/TWI775723B/zh active
- 2016-03-17 HU HUE16765061A patent/HUE057266T2/hu unknown
- 2016-03-17 ES ES16765061T patent/ES2904511T3/es active Active
- 2016-03-17 KR KR1020237022162A patent/KR102813010B1/ko active Active
- 2016-03-17 CN CN202110577382.4A patent/CN113292558A/zh active Pending
- 2016-03-17 CN CN201680016083.0A patent/CN107614500B/zh active Active
- 2016-03-17 JP JP2017506606A patent/JP6692345B2/ja active Active
- 2016-03-17 PL PL16765061T patent/PL3272750T3/pl unknown
- 2016-03-17 BR BR112017019805-3A patent/BR112017019805B1/pt active IP Right Grant
- 2016-03-17 MX MX2021008741A patent/MX2021008741A/es unknown
- 2016-03-17 CN CN202110578658.0A patent/CN113292559B/zh active Active
- 2016-03-17 MA MA41790A patent/MA41790B1/fr unknown
- 2016-03-17 RU RU2017134286A patent/RU2762567C2/ru active
- 2016-03-17 WO PCT/JP2016/058475 patent/WO2016148232A1/fr not_active Ceased
- 2016-03-17 CA CA2979023A patent/CA2979023C/fr active Active
- 2016-03-17 DK DK16765061.3T patent/DK3272750T3/da active
- 2016-03-17 AU AU2016234222A patent/AU2016234222C1/en active Active
- 2016-03-17 EP EP16765061.3A patent/EP3272750B1/fr active Active
- 2016-03-17 TW TW111126713A patent/TWI778933B/zh active
- 2016-03-17 US US15/558,026 patent/US10442802B2/en active Active
- 2016-03-17 MY MYPI2017703345A patent/MY197742A/en unknown
- 2016-03-17 KR KR1020177029778A patent/KR102551969B1/ko active Active
- 2016-03-17 EP EP21203556.2A patent/EP3974430A1/fr active Pending
- 2016-03-17 SG SG11201707427TA patent/SG11201707427TA/en unknown
- 2016-03-17 MX MX2017011824A patent/MX384744B/es unknown
- 2016-03-17 SG SG10201907667RA patent/SG10201907667RA/en unknown
2017
- 2017-09-11 PH PH12017501655A patent/PH12017501655B1/en unknown
- 2017-09-13 IL IL254473A patent/IL254473B/en unknown
- 2017-10-11 ZA ZA2017/06882A patent/ZA201706882B/en unknown
2019
- 2019-07-19 US US16/517,081 patent/US10995092B2/en active Active
2020
- 2020-04-10 JP JP2020071041A patent/JP2020117533A/ja not_active Ceased
- 2020-10-13 US US17/069,589 patent/US11643411B2/en active Active
- 2020-11-18 AU AU2020270503A patent/AU2020270503C9/en active Active
2022
- 2022-01-18 CY CY20221100041T patent/CY1124908T1/el unknown
- 2022-03-18 JP JP2022044083A patent/JP7375076B2/ja active Active
2023
- 2023-01-09 US US18/094,687 patent/US20230159530A1/en active Pending
- 2023-10-25 JP JP2023183221A patent/JP2024010098A/ja active Pending
2025
- 2025-06-10 JP JP2025096247A patent/JP2025131782A/ja active Pending

Also Published As

Publication number	Publication date
CA2979023C (fr)	2023-09-26
AU2020270503C9 (en)	2024-02-29
JP2024010098A (ja)	2024-01-23
KR102813010B1 (ko)	2025-05-26
TW202244044A (zh)	2022-11-16
KR102551969B1 (ko)	2023-07-05
KR20180002616A (ko)	2018-01-08
IL254473B (en)	2022-05-01
AU2020270503C1 (en)	2023-08-10
ES2904511T3 (es)	2022-04-05
US20210040094A1 (en)	2021-02-11
NZ735939A (en)	2024-09-27
ZA201706882B (en)	2022-02-23
RU2762567C2 (ru)	2021-12-21
MX2021008741A (es)	2022-11-01
BR112017019805B1 (pt)	2023-01-31
RU2017134286A (ru)	2019-04-05
DK3272750T3 (en)	2022-01-03
WO2016148232A1 (fr)	2016-09-22
AU2020270503A1 (en)	2020-12-17
RU2017134286A3 (fr)	2019-04-19
JPWO2016148232A1 (ja)	2018-03-08
CN107614500B (zh)	2021-06-15
SG11201707427TA (en)	2017-10-30
TW201638089A (zh)	2016-11-01
PH12017501655A1 (en)	2018-03-12
EP3272750A4 (fr)	2018-08-08
KR20230104767A (ko)	2023-07-10
US20230159530A1 (en)	2023-05-25
CY1124908T1 (el)	2023-01-05
CA2979023A1 (fr)	2016-09-22
MX384744B (es)	2025-03-14
CN113292559B (zh)	2024-04-02
EP3974430A1 (fr)	2022-03-30
HUE057266T2 (hu)	2022-05-28
SG10201907667RA (en)	2019-09-27
JP2020117533A (ja)	2020-08-06
CN113292558A (zh)	2021-08-24
AU2016234222A1 (en)	2017-10-26
US20200079775A1 (en)	2020-03-12
IL254473A0 (en)	2017-11-30
US10995092B2 (en)	2021-05-04
JP2025131782A (ja)	2025-09-09
AU2016234222B2 (en)	2020-08-27
US10442802B2 (en)	2019-10-15
TWI775723B (zh)	2022-09-01
CN113292559A (zh)	2021-08-24
BR112017019805A2 (pt)	2018-05-29
TWI778933B (zh)	2022-09-21
JP7375076B2 (ja)	2023-11-07
HK1249900A1 (en)	2018-11-16
PH12017501655B1 (en)	2022-07-22
JP6692345B2 (ja)	2020-05-13
JP2022081656A (ja)	2022-05-31
PL3272750T3 (pl)	2022-03-07
MA41790B1 (fr)	2022-02-28
AU2020270503B2 (en)	2023-02-02
EP3272750B1 (fr)	2021-11-03
EP3272750A1 (fr)	2018-01-24
MY197742A (en)	2023-07-12
MX2017011824A (es)	2018-04-20
US11643411B2 (en)	2023-05-09
CN107614500A (zh)	2018-01-19
AU2020270503B9 (en)	2023-10-12
AU2016234222C1 (en)	2021-02-11
US20180057493A1 (en)	2018-03-01

Publication	Publication Date	Title
DK3319956T3 (da)	2021-03-29	Substituerede oxopyridinderivater
DK3283625T3 (da)	2020-03-02	Nukleasemedieret genomeditering
PT3157915T (pt)	2019-05-16	Compostos de dihidroisoquinolinona substituídos
DK3277719T3 (da)	2022-05-02	Polypeptider
DK3305788T3 (da)	2020-09-28	Janus-kinase-hæmmer
PT3298027T (pt)	2022-01-26	Compostos depsipéptidos antelmínticos
EP3219592C0 (fr)	2024-08-21	Fixation
LT3402792T (lt)	2021-12-10	Chinolin-2-ono dariniai
MA41790A (fr)	2021-06-02	Dérivé de morphinane
DK3270930T3 (da)	2021-10-04	Præeklampsi
LT3457851T (lt)	2021-10-11	Sobetiromo dariniai
LT3371168T (lt)	2020-10-12	Indolin-2-ono dariniai
CL2016002165A1 (es)	2017-06-09	Compuestos de aminocarbonilcarbamato
EP3309163A4 (fr)	2019-01-09	Dérivé de dihydropyrrolopyrazole substitué
PT3131898T (pt)	2020-06-17	Derivados de fluoroalquilfluoreno
LT3256486T (lt)	2020-06-25	Grifitzino mutantai
LT3362444T (lt)	2021-06-25	Junginiai
DK3597189T3 (da)	2022-06-27	Krystallinske forbindelser
DK3292136T3 (da)	2021-03-22	Penicillin-g-acylaser
EP2966074A4 (fr)	2016-09-14	Dérivé de morphinane
DE112015006486A5 (de)	2018-01-04	Inkubationsrinne
DK3274482T3 (da)	2020-01-06	Stenborsknop
EP3444345C0 (fr)	2024-07-10	Dérivé d'arnmicro-143
EP3372589A4 (fr)	2019-04-24	Dérivé pyrimidine
EP3346592A4 (fr)	2019-04-24	Machine tournante