PL3272750T3 - Pochodna morfinanu - Google Patents

Pochodna morfinanu

Info

Publication number: PL3272750T3
Authority: PL; Poland
Prior art keywords: morphinan derivative; morphinan; derivative
Prior art date: 2015-03-17

Application number

PL16765061T

Other languages

English (en)

Inventor

Hiroshi Nagase

Hideaki Fujii

Akiyoshi Saitoh

Eriko Nakata

Masaaki Hirose

Isao OOI

Kohei HAYASHIDA

Original Assignee

Nippon Chemiphar Co., Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-03-17

Filing date

2016-03-17

Publication date

2022-03-07

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56919074&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3272750(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2016-03-17 Application filed by Nippon Chemiphar Co., Ltd. filed Critical Nippon Chemiphar Co., Ltd.

2022-03-07 Publication of PL3272750T3 publication Critical patent/PL3272750T3/pl

Links

INAXVFBXDYWQFN-XHSDSOJGSA-N morphinan Chemical class C1C2=CC=CC=C2[C@]23CCCC[C@H]3[C@@H]1NCC2 INAXVFBXDYWQFN-XHSDSOJGSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Psychology (AREA)
Psychiatry (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Plural Heterocyclic Compounds (AREA)

PL16765061T 2015-03-17 2016-03-17 Pochodna morfinanu PL3272750T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP2015054079		2015-03-17
PCT/JP2016/058475 WO2016148232A1 (ja)	2015-03-17	2016-03-17	モルヒナン誘導体
EP16765061.3A EP3272750B1 (en)	2015-03-17	2016-03-17	Morphinan derivative

Publications (1)

Publication Number	Publication Date
PL3272750T3 true PL3272750T3 (pl)	2022-03-07

Family

ID=56919074

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL16765061T PL3272750T3 (pl)	2015-03-17	2016-03-17	Pochodna morfinanu

Country Status (23)

Country	Link
US (4)	US10442802B2 (pl)
EP (2)	EP3272750B1 (pl)
JP (5)	JP6692345B2 (pl)
KR (2)	KR102813010B1 (pl)
CN (3)	CN107614500B (pl)
AU (2)	AU2016234222C1 (pl)
BR (1)	BR112017019805B1 (pl)
CA (1)	CA2979023C (pl)
CY (1)	CY1124908T1 (pl)
DK (1)	DK3272750T3 (pl)
ES (1)	ES2904511T3 (pl)
HU (1)	HUE057266T2 (pl)
IL (1)	IL254473B (pl)
MA (1)	MA41790B1 (pl)
MX (2)	MX384744B (pl)
MY (1)	MY197742A (pl)
PH (1)	PH12017501655B1 (pl)
PL (1)	PL3272750T3 (pl)
RU (1)	RU2762567C2 (pl)
SG (2)	SG11201707427TA (pl)
TW (2)	TWI778933B (pl)
WO (1)	WO2016148232A1 (pl)
ZA (1)	ZA201706882B (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2979023C (en) *	2015-03-17	2023-09-26	University Of Tsukuba	Morphinan derivative
US20210371422A1 (en)	2016-08-09	2021-12-02	Nippon Chemiphar Co., Ltd.	Morphinan derivative
CN117122598A (zh) *	2016-09-16	2023-11-28	日本化学药品株式会社	吗啡喃衍生物的在阿片δ受体激动剂相关疾病的治疗中的应用
WO2018066532A1 (ja) *	2016-10-03	2018-04-12	学校法人星薬科大学	モルヒナン誘導体を含む医薬組成物及びその鎮痛剤への使用
US20220289748A1 (en)	2019-07-19	2022-09-15	Nippon Chemiphar Co., Ltd.	Method for producing phenol derivative
EP3984982A4 (en)	2019-07-19	2023-01-18	Nippon Chemiphar Co., Ltd.	PROCESS FOR THE PRODUCTION OF A MORPHINANE DERIVATIVE
AU2021332768B2 (en)	2020-08-28	2024-04-18	Nippon Chemiphar Co., Ltd.	Method for preparing morphinan derivative having diaryl ether skeleton using novel copper catalyst
MX2023009942A (es) *	2021-02-26	2023-10-19	Univ Tokyo Science Found	Composicion farmaceutica para el tratamiento o la prevencion de trastornos relacionados con el estres.
CN116997360A (zh) *	2021-02-26	2023-11-03	学校法人东京理科大学	应激相关障碍的治疗或预防用医药组合物
TW202547487A (zh) *	2024-03-18	2025-12-16	學校法人東京理科大學	失樂症的治療或預防用醫藥組成物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2005231995A (ja)	1999-12-22	2005-09-02	Meiji Seika Kaisha Ltd	オピオイドδ受容体アゴニスト／アンタゴニストとして有用なスピロ化合物
DE10161963A1 (de) *	2001-12-17	2003-07-03	Johannes Schuetz	6-Aminomorphinanderivate, Herstellungsverfahren dafür und deren Verwendung
AR044010A1 (es)	2003-04-11	2005-08-24	Janssen Pharmaceutica Nv	Uso de derivados de 4-fenil-4- [1h-imidazol-2-il]- piperidina sustituidos como agonistas delta opioideos no peptidos selectivos, con actividad antidepresiva y ansiolitica
WO2006107254A1 (en)	2005-04-04	2006-10-12	Astrazeneca Ab	Novel diazaspiroalkanes and their use for treatment of ccr8 mediated diseases
JPWO2008001859A1 (ja)	2006-06-30	2009-11-26	学校法人北里研究所	オピオイドδ受容体アゴニスト
CN101918403A (zh)	2007-09-06	2010-12-15	阵列生物制药公司	作为酪氨酸激酶抑制剂的吡唑并吡啶类化合物
AU2010313392B2 (en)	2009-10-30	2015-07-09	Janssen Pharmaceutica Nv	Pyrazines as delta opioid receptor modulators
EP2525659B1 (en)	2010-01-19	2019-02-27	Merck Sharp & Dohme Corp.	PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS
ES2604931T3 (es)	2010-12-23	2017-03-10	Phoenix Pharmalabs, Inc.	Nuevos morfinanos útiles como analgésicos
JP2014073964A (ja)	2011-01-28	2014-04-24	Kitasato Institute	モルヒナン誘導体
HUE032470T2 (en)	2011-09-09	2017-09-28	The Kitasato Inst	Morphinan derivative
WO2014021273A1 (ja) *	2012-07-30	2014-02-06	学校法人北里研究所	モルヒナン誘導体
EP2931725B1 (en)	2012-12-14	2017-02-15	Purdue Pharma LP	Nitrogen containing morphinan derivatives and the use thereof
CA2908805A1 (en)	2013-03-08	2014-09-12	The Kitasato Institute	Morphinan derivative
CA2979023C (en) *	2015-03-17	2023-09-26	University Of Tsukuba	Morphinan derivative
CN117122598A (zh)	2016-09-16	2023-11-28	日本化学药品株式会社	吗啡喃衍生物的在阿片δ受体激动剂相关疾病的治疗中的应用

2016
- 2016-03-17 CA CA2979023A patent/CA2979023C/en active Active
- 2016-03-17 ES ES16765061T patent/ES2904511T3/es active Active
- 2016-03-17 EP EP16765061.3A patent/EP3272750B1/en active Active
- 2016-03-17 AU AU2016234222A patent/AU2016234222C1/en active Active
- 2016-03-17 HU HUE16765061A patent/HUE057266T2/hu unknown
- 2016-03-17 SG SG11201707427TA patent/SG11201707427TA/en unknown
- 2016-03-17 SG SG10201907667RA patent/SG10201907667RA/en unknown
- 2016-03-17 TW TW111126713A patent/TWI778933B/zh active
- 2016-03-17 TW TW105108248A patent/TWI775723B/zh active
- 2016-03-17 CN CN201680016083.0A patent/CN107614500B/zh active Active
- 2016-03-17 PL PL16765061T patent/PL3272750T3/pl unknown
- 2016-03-17 DK DK16765061.3T patent/DK3272750T3/da active
- 2016-03-17 US US15/558,026 patent/US10442802B2/en active Active
- 2016-03-17 EP EP21203556.2A patent/EP3974430A1/en active Pending
- 2016-03-17 BR BR112017019805-3A patent/BR112017019805B1/pt active IP Right Grant
- 2016-03-17 MY MYPI2017703345A patent/MY197742A/en unknown
- 2016-03-17 WO PCT/JP2016/058475 patent/WO2016148232A1/ja not_active Ceased
- 2016-03-17 MX MX2017011824A patent/MX384744B/es unknown
- 2016-03-17 KR KR1020237022162A patent/KR102813010B1/ko active Active
- 2016-03-17 RU RU2017134286A patent/RU2762567C2/ru active
- 2016-03-17 MA MA41790A patent/MA41790B1/fr unknown
- 2016-03-17 KR KR1020177029778A patent/KR102551969B1/ko active Active
- 2016-03-17 CN CN202110578658.0A patent/CN113292559B/zh active Active
- 2016-03-17 JP JP2017506606A patent/JP6692345B2/ja active Active
- 2016-03-17 CN CN202110577382.4A patent/CN113292558A/zh active Pending
- 2016-03-17 MX MX2021008741A patent/MX2021008741A/es unknown
2017
- 2017-09-11 PH PH12017501655A patent/PH12017501655B1/en unknown
- 2017-09-13 IL IL254473A patent/IL254473B/en unknown
- 2017-10-11 ZA ZA2017/06882A patent/ZA201706882B/en unknown
2019
- 2019-07-19 US US16/517,081 patent/US10995092B2/en active Active
2020
- 2020-04-10 JP JP2020071041A patent/JP2020117533A/ja not_active Ceased
- 2020-10-13 US US17/069,589 patent/US11643411B2/en active Active
- 2020-11-18 AU AU2020270503A patent/AU2020270503C9/en active Active
2022
- 2022-01-18 CY CY20221100041T patent/CY1124908T1/el unknown
- 2022-03-18 JP JP2022044083A patent/JP7375076B2/ja active Active
2023
- 2023-01-09 US US18/094,687 patent/US20230159530A1/en active Pending
- 2023-10-25 JP JP2023183221A patent/JP2024010098A/ja active Pending
2025
- 2025-06-10 JP JP2025096247A patent/JP2025131782A/ja active Pending

Also Published As

Publication number	Publication date
EP3272750A1 (en)	2018-01-24
CN107614500A (zh)	2018-01-19
TW201638089A (zh)	2016-11-01
TWI778933B (zh)	2022-09-21
MX2017011824A (es)	2018-04-20
TW202244044A (zh)	2022-11-16
CN113292558A (zh)	2021-08-24
KR102813010B1 (ko)	2025-05-26
EP3272750B1 (en)	2021-11-03
IL254473B (en)	2022-05-01
MX2021008741A (es)	2022-11-01
MA41790A (fr)	2021-06-02
JP2020117533A (ja)	2020-08-06
JP2024010098A (ja)	2024-01-23
MX384744B (es)	2025-03-14
JPWO2016148232A1 (ja)	2018-03-08
PH12017501655B1 (en)	2022-07-22
SG10201907667RA (en)	2019-09-27
ES2904511T3 (es)	2022-04-05
AU2016234222A1 (en)	2017-10-26
JP2025131782A (ja)	2025-09-09
PH12017501655A1 (en)	2018-03-12
KR20180002616A (ko)	2018-01-08
JP6692345B2 (ja)	2020-05-13
MA41790B1 (fr)	2022-02-28
CN107614500B (zh)	2021-06-15
KR20230104767A (ko)	2023-07-10
AU2020270503B2 (en)	2023-02-02
RU2017134286A (ru)	2019-04-05
AU2020270503B9 (en)	2023-10-12
US20210040094A1 (en)	2021-02-11
JP2022081656A (ja)	2022-05-31
CN113292559A (zh)	2021-08-24
EP3974430A1 (en)	2022-03-30
AU2020270503C1 (en)	2023-08-10
AU2020270503A1 (en)	2020-12-17
AU2020270503C9 (en)	2024-02-29
US11643411B2 (en)	2023-05-09
MY197742A (en)	2023-07-12
CA2979023C (en)	2023-09-26
ZA201706882B (en)	2022-02-23
US20200079775A1 (en)	2020-03-12
KR102551969B1 (ko)	2023-07-05
US10442802B2 (en)	2019-10-15
JP7375076B2 (ja)	2023-11-07
DK3272750T3 (en)	2022-01-03
CY1124908T1 (el)	2023-01-05
WO2016148232A1 (ja)	2016-09-22
RU2762567C2 (ru)	2021-12-21
US20180057493A1 (en)	2018-03-01
AU2016234222B2 (en)	2020-08-27
HUE057266T2 (hu)	2022-05-28
HK1249900A1 (en)	2018-11-16
US10995092B2 (en)	2021-05-04
EP3272750A4 (en)	2018-08-08
IL254473A0 (en)	2017-11-30
BR112017019805A2 (pt)	2018-05-29
TWI775723B (zh)	2022-09-01
AU2016234222C1 (en)	2021-02-11
US20230159530A1 (en)	2023-05-25
CA2979023A1 (en)	2016-09-22
CN113292559B (zh)	2024-04-02
BR112017019805B1 (pt)	2023-01-31
NZ735939A (en)	2024-09-27
RU2017134286A3 (pl)	2019-04-19
SG11201707427TA (en)	2017-10-30

Publication	Publication Date	Title
ZA201800826B (en)	2021-08-25	Substituted oxopyridine derivatives
PL3204359T3 (pl)	2021-03-22	Pochodne tetrahydroizochinoliny
IL253381B (en)	2020-10-29	History of h9–pyrrolo–dipyridine
ZA201706882B (en)	2022-02-23	Morphinan derivative
ZA201704602B (en)	2018-08-29	Dihydroindolizinone derivative
PL3418273T3 (pl)	2022-08-01	Pochodne flawaglin
HUE050450T2 (hu)	2020-12-28	Fluoralkil-fluorén-származékok
IL248773A0 (en)	2017-01-31	History of naphthyridinedione
IL251005B (en)	2020-03-31	Pyrido-oxazinone derivatives
AP2016009530A0 (en)	2016-10-31	Cycloalkyl-linked diheterocycle derivatives
PL3119744T3 (pl)	2019-07-31	Pochodne 2-cyjano-3-cyklopropylo-3-hydroksy-N-arylo-tioakryloamidu
IL248772A0 (en)	2017-01-31	A consequence of cyclohexyl pyridine
GB2537912B (en)	2019-02-13	Anti-ligature bracket
SG10201510721SA (en)	2016-08-30	Bracket
ZA201802194B (en)	2019-01-30	Aminoazole derivative
GB2533834B (en)	2017-11-08	Locator
GB201617732D0 (en)	2016-12-07	Corbel-Pro
GB201510068D0 (en)	2015-07-22	Flexi-wing bracket
GB201508516D0 (en)	2015-07-01	Bracket
AU361522S (en)	2015-04-30	Bracket